Published in Nat Immunol on November 30, 2003
Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet (2008) 7.07
Antigen-independent memory CD8 T cells do not develop during chronic viral infection. Proc Natl Acad Sci U S A (2004) 4.56
Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection. Proc Natl Acad Sci U S A (2007) 2.48
Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination. J Virol (2005) 2.06
Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2. Nat Immunol (2009) 1.73
Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. J Immunol (2008) 1.63
A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis. Cancer Res (2009) 1.48
Memory CD8+ T cell differentiation. Ann N Y Acad Sci (2010) 1.47
IL-15 regulates both quantitative and qualitative features of the memory CD8 T cell pool. J Immunol (2009) 1.45
T-cell intrinsic and extrinsic mechanisms of p27Kip1 in the regulation of CD8 T-cell memory. Immunol Cell Biol (2012) 1.41
Avidity maturation of memory CD8 T cells is limited by self-antigen expression. J Exp Med (2008) 1.38
Diversity in CD8(+) T cell differentiation. Curr Opin Immunol (2009) 1.32
CD8 T cell recall responses are regulated by the tissue tropism of the memory cell and pathogen. J Immunol (2006) 1.24
An essential role for IFN-gamma in regulation of alloreactive CD8 T cells following allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant (2007) 1.12
CD8 T cell quiescence revisited. Trends Immunol (2012) 1.11
Reciprocal responsiveness to interleukin-12 and interferon-alpha specifies human CD8+ effector versus central memory T-cell fates. Blood (2009) 1.08
The CD8+ memory T-cell state of readiness is actively maintained and reversible. Blood (2009) 1.08
Cytoplasmic-nuclear trafficking of G1/S cell cycle molecules and adult human β-cell replication: a revised model of human β-cell G1/S control. Diabetes (2013) 1.06
Virtual memory CD8 T cells display unique functional properties. Proc Natl Acad Sci U S A (2013) 1.04
Enhanced expression of cell cycle regulatory genes in virus-specific memory CD8+ T cells. J Virol (2004) 1.04
Phenotype and functional characterization of long-term gp100-specific memory CD8+ T cells in disease-free melanoma patients before and after boosting immunization. Clin Cancer Res (2008) 1.02
CDK6 levels regulate quiescence exit in human hematopoietic stem cells. Cell Stem Cell (2015) 1.00
Real-time tracking of cell cycle progression during CD8+ effector and memory T-cell differentiation. Nat Commun (2015) 1.00
Human pancreatic β-cell G1/S molecule cell cycle atlas. Diabetes (2013) 0.99
Memory CD8+ T cells exhibit increased antigen threshold requirements for recall proliferation. J Exp Med (2014) 0.98
Regulation of memory CD8 T-cell differentiation by cyclin-dependent kinase inhibitor p27Kip1. Mol Cell Biol (2010) 0.93
The complex and central role of interferon-γ in graft-versus-host disease and graft-versus-tumor activity. Immunol Rev (2014) 0.91
Inflammatory IL-15 is required for optimal memory T cell responses. J Clin Invest (2015) 0.88
Balance between NF-κB p100 and p52 regulates T cell costimulation dependence. J Immunol (2012) 0.87
Early Decision: Effector and Effector Memory T Cell Differentiation in Chronic Infection. Curr Immunol Rev (2013) 0.85
Mitochondrial uncoupling protein 2 induces cell cycle arrest and necrotic cell death. Metab Syndr Relat Disord (2013) 0.79
Multifactorial relationships between intramammary invasion by Staphylococcus aureus and bovine leukocyte markers. Can J Vet Res (2007) 0.79
Gammaherpesvirus latency differentially impacts the generation of primary versus secondary memory CD8+ T cells during subsequent infection. J Virol (2014) 0.79
The Timing of T Cell Priming and Cycling. Front Immunol (2015) 0.78
Dysfunctional memory CD8+ T cells after priming in the absence of the cell cycle regulator E2F4. Cell Immunol (2009) 0.77
ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells. J Clin Invest (2016) 0.76
MicroRNA Expression Patterns of CD8+ T Cells in Acute and Chronic Brucellosis. PLoS One (2016) 0.75
Roscovitine suppresses CD4+ T cells and T cell-mediated experimental uveitis. PLoS One (2013) 0.75
The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells. Biol Direct (2016) 0.75
miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb. Cell Rep (2017) 0.75
A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory. Science (2002) 4.21
A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127. Nat Immunol (2006) 3.74
CD8 lethargy in the absence of CD4 help. Eur J Immunol (2002) 1.98
The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs. Nat Immunol (2005) 1.98
Quantification of multiple gene expression in individual cells. Genome Res (2004) 1.81
Homeostasis of T cell numbers: from thymus production to peripheral compartmentalization and the indexation of regulatory T cells. Semin Immunol (2005) 1.45
CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response. J Exp Med (2007) 1.41
A unique subpopulation of CD4+ regulatory T cells controls wasting disease, IL-10 secretion and T cell homeostasis. Eur J Immunol (2003) 1.28
A human postnatal lymphoid progenitor capable of circulating and seeding the thymus. J Exp Med (2007) 1.21
Characterization of T cell differentiation in the murine gut. J Exp Med (2002) 1.14
Thymocytes may persist and differentiate without any input from bone marrow progenitors. J Exp Med (2012) 1.12
Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse. J Immunol (2007) 1.11
Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors. Blood (2012) 1.02
Extrathymic hemopoietic progenitors committed to T cell differentiation in the adult mouse. J Immunol (2005) 0.99
Cartography of gene expression in CD8 single cells: novel CCR7- subsets suggest differentiation independent of CD45RA expression. Blood (2007) 0.98
Gamma(c) deficiency precludes CD8+ T cell memory despite formation of potent T cell effectors. Proc Natl Acad Sci U S A (2010) 0.95
CD8 and B cell memory: same strategy, same signals. Nat Immunol (2003) 0.94
Major T cell progenitor activity in bone marrow-derived spleen colonies. J Exp Med (2002) 0.86
Epitope specificity and relative clonal abundance do not affect CD8 differentiation patterns during lymphocytic choriomeningitis virus infection. J Virol (2009) 0.83
Role of TCR-restricting MHC density and thymic environment on selection and survival of cells expressing low-affinity T cell receptors. Eur J Immunol (2004) 0.82
Cell-to-cell interactions and signals involved in the reconstitution of peripheral CD8 T(CM) and T(EM) cell pools. PLoS One (2011) 0.81
Role of the gut as a primary lymphoid organ. Immunol Lett (2011) 0.80
Proximal changes in signal transduction that modify CD8+ T cell responsiveness in vivo. Eur J Immunol (2003) 0.80
Homeostasis of naive T cells: the Foxo that fixes. Nat Immunol (2009) 0.80
Single insulin-specific CD8+ T cells show characteristic gene expression profiles in human type 1 diabetes. Diabetes (2011) 0.79
Single-cell analysis of thymocyte differentiation: identification of transcription factor interactions and a major stochastic component in αβ-lineage commitment. PLoS One (2013) 0.76
Correction: Depletion of Regulatory T Cells Induces High Numbers of Dendritic Cells and Unmasks a Subset of Anti-Tumour CD8+CD11c+ PD-1lo Effector T Cells. PLoS One (2017) 0.75
Transcriptional regulation during CD8 T-cell immune responses. Adv Exp Med Biol (2010) 0.75