Published in Neuropharmacology on January 01, 2004
Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid receptors. Br J Pharmacol (2004) 1.04
The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels. Mol Pharmacol (2007) 1.97
Progress in the proxifan class: heterocyclic congeners as novel potent and selective histamine H(3)-receptor antagonists. Eur J Pharm Sci (2002) 1.53
Histamine and its receptors. Br J Pharmacol (2006) 1.53
Voltage gated ion channels: targets for anticonvulsant drugs. Curr Top Med Chem (2005) 1.10
Stem cell therapy for Alport syndrome: the hope beyond the hype. Nephrol Dial Transplant (2008) 1.07
Protean agonism at histamine H3 receptors in vitro and in vivo. Proc Natl Acad Sci U S A (2003) 1.04
Search for the pharmacophore in prazosin for Transport-P. Bioorg Med Chem (2005) 1.02
Seeking a mechanism of action for the novel anticonvulsant lacosamide. Neuropharmacology (2006) 1.00
Differential short-term plasticity at convergent inhibitory synapses to the substantia nigra pars reticulata. J Neurosci (2010) 0.96
Enhancement of hippocampal pyramidal cell excitability by the novel selective slow-afterhyperpolarization channel blocker 3-(triphenylmethylaminomethyl)pyridine (UCL2077). Mol Pharmacol (2006) 0.92
Aberrant GABA(A) receptor expression in the dentate gyrus of the epileptic mutant mouse stargazer. J Neurosci (2006) 0.90
Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR). Bioorg Med Chem Lett (2008) 0.89
The slow afterhyperpolarization: a target of β1-adrenergic signaling in hippocampus-dependent memory retrieval. J Neurosci (2013) 0.88
Anticonvulsant properties of saponins from Ficus platyphylla stem bark. Brain Res Bull (2008) 0.88
A double-blind placebo-controlled randomized trial of Melissa officinalis oil and donepezil for the treatment of agitation in Alzheimer's disease. Dement Geriatr Cogn Disord (2011) 0.86
Pharmacological profile of essential oils derived from Lavandula angustifolia and Melissa officinalis with anti-agitation properties: focus on ligand-gated channels. J Pharm Pharmacol (2008) 0.86
Tritylamino aromatic heterocycles and related carbinols as blockers of ca 2+-activated potassium ion channels underlying neuronal hyperpolarization. Arch Pharm (Weinheim) (2002) 0.83
The sleep hormone oleamide modulates inhibitory ionotropic receptors in mammalian CNS in vitro. Br J Pharmacol (2002) 0.83
Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity. J Med Chem (2002) 0.83
Modulation and function of the autaptic connections of layer V fast spiking interneurons in the rat neocortex. J Physiol (2010) 0.82
Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders. Med Sci Monit (2003) 0.80
Molecular features of the prazosin molecule required for activation of Transport-P. Bioorg Med Chem (2008) 0.80
GABAA alpha6-containing receptors are selectively compromised in cerebellar granule cells of the ataxic mouse, stargazer. J Biol Chem (2007) 0.79
Pharmacological profile of an essential oil derived from Melissa officinalis with anti-agitation properties: focus on ligand-gated channels. J Pharm Pharmacol (2008) 0.79
Refined docking as a valuable tool for lead optimization: application to histamine H3 receptor antagonists. Arch Pharm (Weinheim) (2008) 0.78
Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds. J Med Chem (2003) 0.78
Bis-quinolinium cyclophanes: toward a pharmacophore model for the blockade of apamin-sensitive SKCa channels in sympathetic neurons. Bioorg Med Chem Lett (2004) 0.78
Piperidino-hydrocarbon compounds as novel non-imidazole histamine H(3)-receptor antagonists. Bioorg Med Chem (2002) 0.77
Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SK(Ca)). Bioorg Med Chem (2007) 0.77
Partial structures of ketoconazole as modulators of the large conductance calcium-activated potassium channel (BK(Ca)). Bioorg Med Chem Lett (2005) 0.77
Structural variations of 1-(4-(phenoxymethyl)benzyl)piperidines as nonimidazole histamine H3 receptor antagonists. Bioorg Med Chem (2004) 0.77
Imidazole derivatives as a novel class of hybrid compounds with inhibitory histamine N-methyltransferase potencies and histamine hH3 receptor affinities. Bioorg Med Chem (2003) 0.77
Search for histamine H(3) receptor ligands with combined inhibitory potency at histamine N-methyltransferase: omega-piperidinoalkanamine derivatives. Arch Pharm (Weinheim) (2004) 0.76
Further studies on bis-charged tetraazacyclophanes as potent inhibitors of small conductance Ca(2+)-activated K+ channels. Eur J Med Chem (2013) 0.76
Tin protoporphyrin provides protection following cerebral hypoxia-ischemia: involvement of alternative pathways. J Neurosci Res (2011) 0.76
Inhibition of the antigen-induced activation of RBL-2H3 cells by cetiedil and some of its analogues. Eur J Pharmacol (2004) 0.75
The sleep lipid oleamide may represent an endogenous anticonvulsant: an in vitro comparative study in the 4-aminopyridine rat brain-slice model. Neuropharmacology (2004) 0.75
Reference intervals and age-related changes for venous biochemical, hematological, electrolytic, and blood gas variables using a point of care analyzer in 68 puppies. J Vet Emerg Crit Care (San Antonio) (2014) 0.75
Influence of bulky substituents on histamine h(3) receptor agonist/antagonist properties. J Med Chem (2002) 0.75
4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists. J Med Chem (2004) 0.75
Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry. Bioorg Med Chem Lett (2004) 0.75
Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain. J Med Chem (2004) 0.75