PubRank

Seiichiro Ogawa

Author PubWeight™ 10.28‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Chemical chaperone therapy for brain pathology in G(M1)-gangliosidosis. Proc Natl Acad Sci U S A 2003 1.57
2 N-octyl-beta-valienamine up-regulates activity of F213I mutant beta-glucosidase in cultured cells: a potential chemical chaperone therapy for Gaucher disease. Biochim Biophys Acta 2004 1.05
3 Chaperone therapy for neuronopathic lysosomal diseases: competitive inhibitors as chemical chaperones for enhancement of mutant enzyme activities. Perspect Medicin Chem 2009 0.96
4 Total Synthesis of Natural PI-091, a New Platelet Aggregation Inhibitor of Microbial Origin. J Org Chem 1996 0.96
5 Chemical chaperone therapy: clinical effect in murine G(M1)-gangliosidosis. Ann Neurol 2007 0.93
6 Enzyme enhancement activity of N-octyl-beta-valienamine on beta-glucosidase mutants associated with Gaucher disease. Biochim Biophys Acta 2007 0.89
7 Fibroblast screening for chaperone therapy in beta-galactosidosis. Brain Dev 2006 0.88
8 Chemical chaperone therapy: chaperone effect on mutant enzyme and cellular pathophysiology in β-galactosidase deficiency. Hum Mutat 2011 0.85
9 Therapeutic chaperone effect of N-octyl 4-epi-β-valienamine on murine G(M1)-gangliosidosis. Mol Genet Metab 2012 0.82
10 Concise syntheses of potent chaperone drug candidates, N-octyl-4-epi-β-valinenamine (NOEV) and its 6-deoxy derivative, from (+)-proto-quercitol. Carbohydr Res 2012 0.77
11 A new, convenient cell-based screening method for small-molecule glycolytic inhibitors. Biosci Biotechnol Biochem 2011 0.76
12 Chemical chaperone therapy: luciferase assay for screening of β-galactosidase mutations. Mol Genet Metab 2010 0.75
13 The medicinal chemistry of Glycosidase Inhibitors. Curr Top Med Chem 2009 0.75
14 The effect of N-octyl-β-valienamine on β-glucosidase activity in tissues of normal mice. Brain Dev 2010 0.75
15 Transformation of quercitols into 4-methylenecyclohex-5-ene-1,2,3-triol derivatives, precursors for the chemical chaperones N-octyl-4-epi-β-valienamine (NOEV) and N-octyl-β-valienamine (NOV). Bioorg Med Chem Lett 2011 0.75
16 Potent and specific sialyltransferase inhibitors: imino-linked 5a'-carbadisaccharides. Org Biomol Chem 2003 0.75
17 5a-Carba-glycopyranoside primers: potential building blocks for biocombinatorial synthesis of glycosphingolipid analogues. Carbohydr Res 2009 0.75
18 The pharmacological chaperone effect of N-octyl-beta-valienamine on human mutant acid beta-glucosidases. Blood Cells Mol Dis 2009 0.75