Published in Ann N Y Acad Sci on November 01, 2003
Human beta-cell precursors mature into functional insulin-producing cells in an immunoisolation device: implications for diabetes cell therapies. Transplantation (2009) 1.09
Role of the mitochondria in immune-mediated apoptotic death of the human pancreatic β cell line βLox5. PLoS One (2011) 0.91
Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model. Mol Pharm (2011) 0.88
Glucose-regulated insulin production in the liver improves glycemic control in type 1 diabetic mice. Mol Metab (2014) 0.77
Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell (2008) 4.63
A chemical platform for improved induction of human iPSCs. Nat Methods (2009) 4.54
Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc Natl Acad Sci U S A (2006) 3.90
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. Development (2011) 3.11
Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc Natl Acad Sci U S A (2010) 3.01
Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas. Nat Med (2006) 2.41
Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells (2009) 2.29
Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation. Proc Natl Acad Sci U S A (2009) 2.02
Pancreatic β-cell neogenesis by direct conversion from mature α-cells. Stem Cells (2010) 1.80
A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. Cell Stem Cell (2013) 1.59
A novel approach to increase human islet cell mass while preserving beta-cell function. Diabetes (2002) 1.43
Progenitor cell domains in the developing and adult pancreas. Cell Cycle (2011) 1.20
Cryopreservation by slow cooling with DMSO diminished production of Oct-4 pluripotency marker in human embryonic stem cells. Cryobiology (2006) 1.15
Human beta-cell precursors mature into functional insulin-producing cells in an immunoisolation device: implications for diabetes cell therapies. Transplantation (2009) 1.09
Prediction of the glass transition temperature of water solutions: comparison of different models. Cryobiology (2004) 1.06
Limited capacity of human adult islets expanded in vitro to redifferentiate into insulin-producing beta-cells. Diabetes (2007) 1.01
Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic beta-cells. Proc Natl Acad Sci U S A (2009) 0.98
Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells. J Biol Chem (2010) 0.96
Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells. Islets (2011) 0.94
Islet specific Wnt activation in human type II diabetes. Exp Diabetes Res (2009) 0.93
c-Myc controls proliferation versus differentiation in human pancreatic endocrine cells. J Clin Endocrinol Metab (2002) 0.92
Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes. BMC Endocr Disord (2002) 0.92
CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells. Aging (Albany NY) (2010) 0.89
Chronic treatment of mitochondrial disease patients with dichloroacetate. Mol Genet Metab (2004) 0.89
HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chem Biol (2012) 0.88
Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen. J Biomol Screen (2010) 0.88
NOTCH1 signaling promotes human T-cell acute lymphoblastic leukemia initiating cell regeneration in supportive niches. PLoS One (2012) 0.87
HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion. Biochem Biophys Res Commun (2007) 0.86
Adult pancreatic alpha-cells: a new source of cells for beta-cell regeneration. Rev Diabet Stud (2010) 0.86
Interleukin 7 and thymic stromal lymphopoietin: from immunity to leukemia. Cell Mol Life Sci (2013) 0.86
Telomere-independent cellular senescence in human fetal cardiomyocytes. Aging Cell (2005) 0.84
The Id3/E47 axis mediates cell-cycle control in human pancreatic ducts and adenocarcinoma. Mol Cancer Res (2011) 0.84
T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion. Islets (2011) 0.83
Efficient β-cell regeneration by a combination of neogenesis and replication following β-cell ablation and reversal of pancreatic duct ligation. Stem Cells (2013) 0.82
β-Cell replication and islet neogenesis following partial pancreatectomy. Islets (2011) 0.82
The SDF-1α/CXCR4 axis is required for proliferation and maturation of human fetal pancreatic endocrine progenitor cells. PLoS One (2012) 0.79
Induction of β-cell replication by a synthetic HNF4α antagonist. Stem Cells (2013) 0.78
Derivation of a retinoid X receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene. ChemMedChem (2009) 0.77
Identification of alverine and benfluorex as HNF4α activators. ACS Chem Biol (2013) 0.75
HIGH YIELD OF RODENT ISLETS WITH INTRADUCTAL COLLAGENASE AND STATIONARY DIGESTION-A COMPARISON WITH STANDARD TECHNIQUE. Cell Transplant (1996) 0.75
Sources of beta-cells for human cell-based therapies for diabetes. Cell Biochem Biophys (2004) 0.75
Thyrotoxic, hypokalemic periodic paralysis (THPP) in adolescents. J Pediatr Endocrinol Metab (2015) 0.75