Shane T Grey

Author PubWeight™ 45.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression. J Exp Med 2009 3.78
2 BAFF and MyD88 signals promote a lupuslike disease independent of T cells. J Exp Med 2007 2.70
3 Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction. J Clin Invest 2003 2.35
4 Role for activating transcription factor 3 in stress-induced beta-cell apoptosis. Mol Cell Biol 2004 2.10
5 Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets. J Clin Invest 2010 1.70
6 Increased CD4+Foxp3+ T cells in BAFF-transgenic mice suppress T cell effector responses. J Immunol 2009 1.43
7 The BAFF/APRIL system: an important player in systemic rheumatic diseases. Curr Dir Autoimmun 2005 1.37
8 A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation. Blood 2004 1.37
9 BAFF augments certain Th1-associated inflammatory responses. J Immunol 2005 1.37
10 Potential antiinflammatory role of insulin via the preferential polarization of effector T cells toward a T helper 2 phenotype. Endocrinology 2006 1.31
11 Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells. Diabetes 2007 1.29
12 Nuclear factor-kappaB regulates beta-cell death: a critical role for A20 in beta-cell protection. Diabetes 2006 1.28
13 CD4(+)CD25(+) T-cells control autoimmunity in the absence of B-cells. Diabetes 2009 1.24
14 B cells in the spotlight: innocent bystanders or major players in the pathogenesis of type 1 diabetes. Trends Endocrinol Metab 2006 1.17
15 A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis. Hepatology 2002 1.17
16 A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia. FASEB J 2006 1.09
17 B cells as effectors and regulators of autoimmunity. Autoimmunity 2012 0.99
18 B cell-directed therapies in type 1 diabetes. Trends Immunol 2011 0.98
19 A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a p21waf1-dependent mechanism. Hepatology 2005 0.97
20 B-cell cross-presentation of autologous antigen precipitates diabetes. Diabetes 2012 0.96
21 A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis. Circulation 2003 0.96
22 IL-2/IL-2Ab complexes induce regulatory T cell expansion and protect against proteinuric CKD. J Am Soc Nephrol 2012 0.96
23 Functional dichotomy of A20 in apoptotic and necrotic cell death. Biochem J 2005 0.95
24 Depleting anti-CD4 monoclonal antibody cures new-onset diabetes, prevents recurrent autoimmune diabetes, and delays allograft rejection in nonobese diabetic mice. Transplantation 2004 0.92
25 Human islets express a marked proinflammatory molecular signature prior to transplantation. Cell Transplant 2012 0.90
26 Invasion of the killer B's in type 1 diabetes. Front Biosci 2007 0.90
27 Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells. Kidney Int 2005 0.87
28 Intrinsic molecular factors cause aberrant expansion of the splenic marginal zone B cell population in nonobese diabetic mice. J Immunol 2013 0.87
29 Expression of pro- and antiapoptotic molecules of the Bcl-2 family in human islets postisolation. Cell Transplant 2011 0.86
30 A preexistent hypoxic gene signature predicts impaired islet graft function and glucose homeostasis. Cell Transplant 2012 0.85
31 Sulindac activates NF-κB signaling in colon cancer cells. Cell Commun Signal 2013 0.85
32 A new role for an old player: do B cells unleash the self-reactive CD8+ T cell storm necessary for the development of type 1 diabetes? J Autoimmun 2008 0.83
33 BAFF regulates activation of self-reactive T cells through B-cell dependent mechanisms and mediates protection in NOD mice. Eur J Immunol 2014 0.82
34 Low-dose rapamycin unmasks the protective potential of targeting intragraft NF-κB for islet transplants. Cell Transplant 2012 0.78
35 Influence of chronic hyperglycemia on the loss of the unfolded protein response in transplanted islets. J Mol Endocrinol 2013 0.77
36 Mice deficient in GEM GTPase show abnormal glucose homeostasis due to defects in beta-cell calcium handling. PLoS One 2012 0.77
37 Emerging roles for A20 in islet biology and pathology. Adv Exp Med Biol 2014 0.76
38 IGF2: an endocrine hormone to improve islet transplant survival. J Endocrinol 2014 0.76
39 Awards in Transplantation Science Recognize the Best Manuscripts Published in Transplantation. Transplantation 2016 0.75
40 Finding a New Home for Islet Cell Transplants. Transplantation 2016 0.75
41 Equipping the islet graft for self defence: targeting nuclear factor κB and implications for tolerance. Curr Opin Organ Transplant 2017 0.75
42 Regulating inflammation: the ying and yang of NF-kappaB activation. Immunol Cell Biol 2008 0.75
43 A20 is an immune tolerance factor that can determine islet transplant outcomes. JCI Insight 2019 0.75
44 B-lymphocyte therapy for Type 2 diabetes: the 'B' side of diabetic medication? Immunotherapy 2013 0.75