Ken-ichi Fujita

Author PubWeight™ 35.86‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation. Curr Biol 2008 1.58
2 Pharmacogenetic impact of polymorphisms in the coding region of the UGT1A1 gene on SN-38 glucuronidation in Japanese patients with cancer. Cancer Sci 2006 1.31
3 Homogeneous catalytic system for reversible dehydrogenation-hydrogenation reactions of nitrogen heterocycles with reversible interconversion of catalytic species. J Am Chem Soc 2009 1.18
4 Cancer prevention by natural compounds. Drug Metab Pharmacokinet 2004 1.11
5 Studies on the interactions between drug and estrogen. II. On the inhibitory effect of 29 drugs reported to induce gynecomastia on the oxidation of estradiol at C-2 or C-17. Biol Pharm Bull 2003 0.96
6 Sorafenib and sunitinib, two anticancer drugs, inhibit CYP3A4-mediated and activate CY3A5-mediated midazolam 1'-hydroxylation. Drug Metab Dispos 2011 0.90
7 A phase I study of infusional 5-fluorouracil, leucovorin, oxaliplatin and irinotecan in Japanese patients with advanced colorectal cancer who harbor UGT1A1*1/*1,*1/*6 or *1/*28. Oncology 2012 0.89
8 Cancer prevention by bovine lactoferrin and underlying mechanisms--a review of experimental and clinical studies. Biochem Cell Biol 2002 0.89
9 Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: application of genetically engineered Salmonella expressing human CYP. Drug Metab Rev 2002 0.89
10 Antibacterial activity of akyl gallates against Bacillus subtilis. J Agric Food Chem 2004 0.88
11 Phase I/II study of FOLFIRI in Japanese patients with advanced colorectal cancer. Jpn J Clin Oncol 2010 0.88
12 Dehydrogenative oxidation of alcohols in aqueous media using water-soluble and reusable Cp*Ir catalysts bearing a functional bipyridine ligand. J Am Chem Soc 2012 0.86
13 Biosynthesis of poly-gamma-glutamic acid in plants: transient expression of poly-gamma-glutamate synthetase complex in tobacco leaves. J Biosci Bioeng 2005 0.86
14 The vacuole-targeting fungicidal activity of amphotericin B against the pathogenic fungus Candida albicans and its enhancement by allicin. J Antibiot (Tokyo) 2009 0.84
15 Transient inhibition of cyp3a in rats by star fruit juice. Drug Metab Dispos 2005 0.83
16 Enhancement of the fungicidal activity of amphotericin B by allicin, an allyl-sulfur compound from garlic, against the yeast Saccharomyces cerevisiae as a model system. Planta Med 2006 0.83
17 Pharmacokinetic study of S-1 in patients in whom inulin clearance was measured. Oncology 2012 0.82
18 A diclofenac suppository-nabumetone combination therapy for arthritic pain relief and a monitoring method for the diclofenac binding capacity of HSA site II in rheumatoid arthritis. Biopharm Drug Dispos 2013 0.82
19 Inhibition of human cytochrome P450 1B1, 1A1 and 1A2 by antigenotoxic compounds, purpurin and alizarin. Mutat Res 2002 0.82
20 Potent inhibition by star fruit of human cytochrome P450 3A (CYP3A) activity. Drug Metab Dispos 2004 0.81
21 A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface. Apoptosis 2011 0.80
22 Visualization analysis of the vacuole-targeting fungicidal activity of amphotericin B against the parent strain and an ergosterol-less mutant of Saccharomyces cerevisiae. Microbiology 2013 0.80
23 Possible application of human c-Ha-ras proto-oncogene transgenic rats in a medium-term bioassay model for carcinogens. Toxicol Pathol 2007 0.80
24 Clinical and economic evaluation of first-line therapy with FOLFIRI or modified FOLFOX6 for metastatic colorectal cancer. Jpn J Clin Oncol 2010 0.80
25 Molecular design of multifunctional antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA). Bioorg Med Chem 2003 0.80
26 Orally administered bovine lactoferrin induces caspase-1 and interleukin-18 in the mouse intestinal mucosa: a possible explanation for inhibition of carcinogenesis and metastasis. Cytokine 2004 0.80
27 Antibacterial activity of polygodial. Phytother Res 2005 0.80
28 Association of ABCC2 genotype with efficacy of first-line FOLFIRI in Japanese patients with advanced colorectal cancer. Drug Metab Pharmacokinet 2011 0.78
29 Antimycin A-induced cell death depends on AIF translocation through NO production and PARP activation and is not involved in ROS generation, cytochrome c release and caspase-3 activation in HL-60 cells. J Antibiot (Tokyo) 2009 0.78
30 Simple and versatile catalytic system for N-alkylation of sulfonamides with various alcohols. Org Lett 2010 0.78
31 Synergistic fungicidal activities of amphotericin B and N-methyl-N"-dodecylguanidine: a constituent of polyol macrolide antibiotic niphimycin. J Antibiot (Tokyo) 2007 0.77
32 Synergistic fungicidal activities of polymyxin B and ionophores, and their dependence on direct disruptive action of polymyxin B on fungal vacuole. J Antibiot (Tokyo) 2009 0.77
33 Imaging of heme/hemeproteins in nucleus of the living cells expressing heme-binding nuclear receptors. FEBS Lett 2013 0.77
34 Dependence of vacuole disruption and independence of potassium ion efflux in fungicidal activity induced by combination of amphotericin B and allicin against Saccharomyces cerevisiae. J Antibiot (Tokyo) 2010 0.77
35 Targeted yeast vacuole disruption by polyene antibiotics with a macrocyclic lactone ring. Int J Antimicrob Agents 2009 0.77
36 Aerobic oxidative amidation of aromatic and cinnamic aldehydes with secondary amines by CuI/2-pyridonate catalytic system. J Org Chem 2012 0.76
37 The cyclic organosulfur compound zwiebelane A from onion (Allium cepa) functions as an enhancer of polymyxin B in fungal vacuole disruption. Planta Med 2010 0.76
38 Efficient synthesis of biazoles by aerobic oxidative homocoupling of azoles catalyzed by a copper(I)/2-pyridonate catalytic system. Chem Commun (Camb) 2011 0.76
39 Multialkylation of aqueous ammonia with alcohols catalyzed by water-soluble Cp*Ir-ammine complexes. J Am Chem Soc 2010 0.76
40 Morphological changes of the filamentous fungus Mucor mucedo and inhibition of chitin synthase activity induced by anethole. Phytother Res 2011 0.76
41 Protective effects of α-tocopherol and ascorbic acid against cardol-induced cell death and reactive oxygen species generation in Staphylococcus aureus. Planta Med 2013 0.76
42 Re: UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters. J Natl Cancer Inst 2008 0.75
43 Synthesis of novel dendritic 2,2'-bipyridine ligands and their application to Lewis acid-catalyzed diels-alder and three-component condensation reactions. J Org Chem 2007 0.75
44 Establishment of an apoptosis-sensitive rat mammary carcinoma cell line with a mutation in the DNA-binding region of p53. Cancer Lett 2006 0.75
45 C-H activation on a diphosphine and hydrido-bridged diiridium complex: generation and detection of an active IrII-IrII species [(Cp*Ir)2(micro-dmpm)(micro-H)]+. Dalton Trans 2008 0.75
46 Cooperative catalysis by iridium complexes with a bipyridonate ligand: versatile dehydrogenative oxidation of alcohols and reversible dehydrogenation-hydrogenation between 2-propanol and acetone. Angew Chem Int Ed Engl 2012 0.75
47 Flocculating activity of cross-linked poly-gamma-glutamic acid against bentonite and Escherichia coli suspension pretreated with FeCl3 and its interaction with Fe3+. J Biosci Bioeng 2005 0.75
48 Inhibitory activity of 1-farnesylpyridinium on the spatial control over the assembly of cell wall polysaccharides in Schizosaccharomyces pombe. J Biochem 2006 0.75
49 Structure-activity relationship studies on UK-2A, a novel antifungal antibiotic from Streptomyces sp. 517-02. Part 5: Roles of the 9-membered dilactone-ring moiety in respiratory inhibition. Bioorg Med Chem Lett 2006 0.75
50 [Need for pharmaceutical skill in using displacement of protein binding]. Yakugaku Zasshi 2007 0.75
51 Three-dimensional structure of the inclusion complex between phloridzin and beta-cyclodextrin. Carbohydr Res 2002 0.75
52 Rapid induction of skin and mammary tumors in human c-Ha-ras proto-oncogene transgenic rats by treatment with 7,12-dimethylbenz[a]anthracene followed by 12-O-tetradecanoylphorbol 13-acetate. Cancer Sci 2004 0.75
53 Selective inhibition of embryonic development in starfish by long-chain alkyl derivatives of UMP, TMP and AMP. Nat Prod Res 2009 0.75
54 UK-2A, B, C, and D, novel antifungal antibiotics from Streptomyces sp. 517-02 VII. Membrane injury induced by C9-UK-2A, a derivative of UK-2A, in Rhodotorula mucilaginosa IFO 0001. J Antibiot (Tokyo) 2002 0.75