Published in Nat Rev Cancer on January 01, 2004
Inflammation in prostate carcinogenesis. Nat Rev Cancer (2007) 9.08
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients. Proc Natl Acad Sci U S A (2008) 4.43
Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance. Cell Cycle (2009) 3.60
The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans. J Clin Invest (2009) 2.42
T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers. Breast Cancer Res (2009) 2.26
MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF. J Clin Invest (2007) 2.24
Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell (2016) 2.15
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression. Genome Res (2012) 2.10
An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis. PLoS One (2010) 2.08
Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation. Cancer Cell (2012) 2.01
Sleep duration associated with mortality in elderly, but not middle-aged, adults in a large US sample. Sleep (2008) 1.98
Role of infiltrated leucocytes in tumour growth and spread. Br J Cancer (2004) 1.98
Cancer-related inflammation. J Clin Immunol (2012) 1.91
Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity. Proc Natl Acad Sci U S A (2006) 1.88
Epidemiological evidence for the links between sleep, circadian rhythms and metabolism. Obes Rev (2009) 1.83
Immuno-oncology: understanding the function and dysfunction of the immune system in cancer. Ann Oncol (2012) 1.73
Differences in the tumor microenvironment between African-American and European-American breast cancer patients. PLoS One (2009) 1.72
Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing. Gastroenterology (2006) 1.68
Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival. Blood (2007) 1.63
MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma. Proc Natl Acad Sci U S A (2008) 1.59
Relation between common polymorphisms in genes related to inflammatory response and colorectal cancer. World J Gastroenterol (2006) 1.52
Retracted A Role for PPARgamma in the Regulation of Cytokines in Immune Cells and Cancer. PPAR Res (2008) 1.48
GK-1 improves the immune response induced by bone marrow dendritic cells loaded with MAGE-AX in mice with melanoma. J Immunol Res (2014) 1.48
Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II. Prostate (2009) 1.45
Retracted Therapeutic Effects of Umbilical Cord Blood Derived Mesenchymal Stem Cell-Conditioned Medium on Pulmonary Arterial Hypertension in Rats. J Pathol Transl Med (2015) 1.43
Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia. Blood (2010) 1.43
Combining radiation and immunotherapy: a new systemic therapy for solid tumors? Cancer Immunol Res (2014) 1.43
Regulation of IGF-I function by proinflammatory cytokines: at the interface of immunology and endocrinology. Cell Immunol (2008) 1.42
Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis. Mol Cancer (2010) 1.36
Nitric oxide is a key component in inflammation-accelerated tumorigenesis. Cancer Res (2008) 1.19
Trial Watch: Immunostimulatory cytokines. Oncoimmunology (2012) 1.19
Endotoxin and cancer. Environ Health Perspect (2009) 1.17
High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity. Anal Chem (2013) 1.16
Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms. J Exp Med (2009) 1.15
The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance. Cancer Cell Int (2014) 1.11
Knockdown of interferon-induced transmembrane protein 1 (IFITM1) inhibits proliferation, migration, and invasion of glioma cells. J Neurooncol (2010) 1.11
Chromosome 3p loss of heterozygosity is associated with a unique metabolic network in clear cell renal carcinoma. Proc Natl Acad Sci U S A (2014) 1.09
Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth. Mol Immunol (2007) 1.07
Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells. FASEB J (2009) 1.06
Inflammation and stem cells in gastrointestinal carcinogenesis. Physiology (Bethesda) (2008) 1.06
Cancer and innate immune system interactions: translational potentials for cancer immunotherapy. J Immunother (2012) 1.05
Pathway-based classification of cancer subtypes. Biol Direct (2012) 1.05
Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with α5β1 integrin in glioma. Oncogene (2012) 1.03
Tristetraprolin: roles in cancer and senescence. Ageing Res Rev (2012) 1.03
Ligation of the OX40 co-stimulatory receptor reverses self-Ag and tumor-induced CD8 T-cell anergy in vivo. Eur J Immunol (2009) 1.03
IL-6 stabilizes Twist and enhances tumor cell motility in head and neck cancer cells through activation of casein kinase 2. PLoS One (2011) 1.02
Cytokine plasma levels: reliable predictors for radiation pneumonitis? PLoS One (2008) 1.02
General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines. J Virol (2007) 1.01
Comparison of the Calibration Standards of Three Commercially Available Multiplex Kits for Human Cytokine Measurement to WHO Standards Reveals Striking Differences. Biomark Insights (2008) 1.00
Ionizing radiation stimulates secretion of pro-inflammatory cytokines: dose-response relationship, mechanisms and implications. Radiat Environ Biophys (2006) 1.00
Factors influencing the long-term survival in patients with esophageal cancer who underwent esophagectomy after chemoradiotherapy. World J Surg (2010) 0.99
Inflammatory and microRNA gene expression as prognostic classifier of Barrett's-associated esophageal adenocarcinoma. Clin Cancer Res (2010) 0.99
Interleukin-17D mediates tumor rejection through recruitment of natural killer cells. Cell Rep (2014) 0.98
Protein disulfide isomerases are antibody targets during immune-mediated tumor destruction. Blood (2008) 0.98
DawnRank: discovering personalized driver genes in cancer. Genome Med (2014) 0.98
Inflammation and the two-hit hypothesis of schizophrenia. Neurosci Biobehav Rev (2013) 0.98
Revisiting immunosurveillance and immunostimulation: Implications for cancer immunotherapy. J Transl Med (2005) 0.97
Aging and inflammation: etiological culprits of cancer. Curr Aging Sci (2009) 0.97
One cell, multiple roles: contribution of mesenchymal stem cells to tumor development in tumor microenvironment. Cell Biosci (2013) 0.97
Rationale for targeting the immune system through checkpoint molecule blockade in the treatment of non-small-cell lung cancer. Ann Oncol (2013) 0.96
PPARs Mediate Lipid Signaling in Inflammation and Cancer. PPAR Res (2008) 0.96
Trial Watch: Immunostimulatory cytokines. Oncoimmunology (2013) 0.96
Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation. Oncotarget (2015) 0.96
Trial watch: Immunostimulatory cytokines in cancer therapy. Oncoimmunology (2014) 0.95
AAV-mediated local delivery of interferon-beta for the treatment of retinoblastoma in preclinical models. Neuromolecular Med (2009) 0.95
Role of TLR2-dependent inflammation in metastatic progression. Ann N Y Acad Sci (2011) 0.94
The effects of mesenchymal stem cells injected via different routes on modified IL-12-mediated antitumor activity. Gene Ther (2011) 0.94
Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rβ2 or IL-18Rα. Gene Ther (2011) 0.93
Bcl-x(L)-mediated changes in metabolic pathways of breast cancer cells: from survival in the blood stream to organ-specific metastasis. Am J Pathol (2005) 0.93
Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation. Cancer Prev Res (Phila) (2013) 0.93
Association between tumor necrosis factor-alpha gene polymorphisms and prostate cancer risk: a meta-analysis. Diagn Pathol (2014) 0.92
Immunotherapy for liver tumors: present status and future prospects. J Biomed Sci (2009) 0.92
The role of funding and policies on innovation in cancer drug development. Ecancermedicalscience (2010) 0.92
Nanoparticles containing anti-inflammatory agents as chemotherapy adjuvants: optimization and in vitro characterization. AAPS J (2008) 0.92
The complex and central role of interferon-γ in graft-versus-host disease and graft-versus-tumor activity. Immunol Rev (2014) 0.91
Common gamma chain cytokines in combinatorial immune strategies against cancer. Immunol Lett (2015) 0.91
Promising novel immunotherapies and combinations for prostate cancer. Future Oncol (2009) 0.91
The biologic importance of tumor-infiltrating lymphocytes. J Cutan Pathol (2010) 0.90
Human breast fibroblasts inhibit growth of the MCF10AT xenograft model of proliferative breast disease. Am J Pathol (2007) 0.88
A mutant collagen XIII alters intestinal expression of immune response genes and predisposes transgenic mice to develop B-cell lymphomas. Cancer Res (2008) 0.88
Immunotherapy and tumor microenvironment. Cancer Lett (2015) 0.88
The transcriptional consequences of somatic amplifications, deletions, and rearrangements in a human lung squamous cell carcinoma. Neoplasia (2012) 0.88
Genome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancers. Genes Chromosomes Cancer (2011) 0.87
Diminished expression of transcription factors nuclear factor kappaB and CCAAT/enhancer binding protein underlies a novel tumor evasion mechanism affecting macrophages of mammary tumor-bearing mice. Cancer Res (2005) 0.87
An Eighteen Serum Cytokine Signature for Discriminating Glioma from Normal Healthy Individuals. PLoS One (2015) 0.87
The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function. Proc Natl Acad Sci U S A (2016) 0.87
High expression of Foxp3, IL-23p19 and survivin mRNA in colorectal carcinoma. Int J Colorectal Dis (2008) 0.87
TNF-alpha levels in cancer patients relate to social variables. Brain Behav Immun (2005) 0.87
The nuclear factor-κB correlates with increased expression of interleukin-6 and promotes progression of gastric carcinoma. Oncol Rep (2012) 0.86
Polymorphisms of ICAM-1 are associated with gastric cancer risk and prognosis. World J Gastroenterol (2012) 0.86
Clinical relevance of serum vascular endothelial growth factor and interleukin-6 in patients with colorectal cancer. Saudi J Gastroenterol (2011) 0.86
On evolutionary origin of cancer. Cancer Cell Int (2005) 0.86
Role of GM-CSF signaling in cell-based tumor immunization. Blood (2009) 0.86
Promoter hypermethylation in tumour suppressor genes and response to interleukin-2 treatment in bladder cancer: a pilot study. J Cancer Res Clin Oncol (2009) 0.85
The role of innate immune signals in immunity to Brucella abortus. Front Cell Infect Microbiol (2012) 0.85
The relationship between COPD and lung cancer. Lung Cancer (2015) 0.85
In silico tumor control induced via alternating immunostimulating and immunosuppressive phases. Virulence (2015) 0.84
Tumor microenvironment B cells increase bladder cancer metastasis via modulation of the IL-8/androgen receptor (AR)/MMPs signals. Oncotarget (2015) 0.84
Regulation of hemichannels and gap junction channels by cytokines in antigen-presenting cells. Mediators Inflamm (2014) 0.83