Published in Int J Cancer on March 20, 2004
P-glycoprotein4 displays auxin efflux transporter-like action in Arabidopsis root hair cells and tobacco cells. Plant Cell (2007) 1.62
In situ localization of P-glycoprotein (ABCB1) in human and rat brain. J Histochem Cytochem (2006) 1.25
P-glycoprotein mediates drug resistance via a novel mechanism involving lysosomal sequestration. J Biol Chem (2013) 1.01
Intracellular trafficking of P-glycoprotein. Int J Biochem Cell Biol (2011) 0.96
P-Glycoprotein is not present in mitochondrial membranes. Exp Cell Res (2007) 0.89
Proteome analysis of multidrug-resistant, breast cancer-derived microparticles. J Extracell Vesicles (2014) 0.87
Cell structure and cytokinesis alterations in multidrug-resistant Leishmania (Leishmania) amazonensis. Parasitol Res (2004) 0.86
Where is it and How Does it Get There - Intracellular Localization and Traffic of P-glycoprotein. Front Oncol (2013) 0.83
Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier. Drug Metab Dispos (2013) 0.83
Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C. PLoS One (2014) 0.82
Ceramide 1-Phosphate Increases P-Glycoprotein Transport Activity at the Blood-Brain Barrier via Prostaglandin E2 Signaling. Mol Pharmacol (2017) 0.75
Visualizing lipid structure and raft domains in living cells with two-photon microscopy. Proc Natl Acad Sci U S A (2003) 3.17
An overview on biological mechanisms of PPARs. Pharmacol Res (2005) 2.43
Presence of Hoechst low side populations in multiple myeloma. Leuk Lymphoma (2008) 1.51
Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800. Pain (2006) 1.41
Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol (2004) 1.40
Fluticasone uptake across Calu-3 cells is mediated by salmeterol when deposited as a combination powder inhaler. Respirology (2013) 1.38
Activation of protein kinase C reverses capsaicin-induced calcium-dependent desensitization of TRPV1 ion channels. Cell Calcium (2004) 1.33
Anti-diabetic action of Punica granatum flower extract: activation of PPAR-gamma and identification of an active component. Toxicol Appl Pharmacol (2005) 1.27
Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. RNA Biol (2013) 1.26
Effective anti-platelet and COX-1 enzyme inhibitors from pungent constituents of ginger. Thromb Res (2003) 1.25
Punica granatum flower extract, a potent alpha-glucosidase inhibitor, improves postprandial hyperglycemia in Zucker diabetic fatty rats. J Ethnopharmacol (2005) 1.23
Mechanisms directing the nuclear localization of the CtBP family proteins. Mol Cell Biol (2006) 1.13
Microparticle-associated nucleic acids mediate trait dominance in cancer. FASEB J (2011) 1.13
Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol (2005) 1.11
Gingerols: a novel class of vanilloid receptor (VR1) agonists. Br J Pharmacol (2002) 1.11
A systematic review on the Rosa canina effect and efficacy profiles. Phytother Res (2008) 1.07
Actin disruption inhibits endosomal traffic of P-glycoprotein-EGFP and resistance to daunorubicin accumulation. Am J Physiol Cell Physiol (2006) 1.06
Pomegranate flower: a unique traditional antidiabetic medicine with dual PPAR-alpha/-gamma activator properties. Diabetes Obes Metab (2008) 1.06
Microparticle conferred microRNA profiles--implications in the transfer and dominance of cancer traits. Mol Cancer (2012) 1.05
Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy? Drug Metab Dispos (2014) 1.05
Culturable endophytes of medicinal plants and the genetic basis for their bioactivity. Microb Ecol (2012) 1.01
Salacia oblonga root improves cardiac lipid metabolism in Zucker diabetic fatty rats: modulation of cardiac PPAR-alpha-mediated transcription of fatty acid metabolic genes. Toxicol Appl Pharmacol (2005) 1.01
Protective effects of ethanolic extract of Zingiber officinale rhizome on the development of metabolic syndrome in high-fat diet-fed rats. Basic Clin Pharmacol Toxicol (2009) 0.99
Breast cancer-derived microparticles display tissue selectivity in the transfer of resistance proteins to cells. PLoS One (2013) 0.99
Herbal or natural medicines as modulators of peroxisome proliferator-activated receptors and related nuclear receptors for therapy of metabolic syndrome. Basic Clin Pharmacol Toxicol (2005) 0.97
Salacia oblonga root improves postprandial hyperlipidemia and hepatic steatosis in Zucker diabetic fatty rats: activation of PPAR-alpha. Toxicol Appl Pharmacol (2005) 0.97
Anti-hyperlipidemic and hypoglycemic effects of Gynostemma pentaphyllum in the Zucker fatty rat. J Pharm Pharm Sci (2006) 0.96
A comprehensive review on the stinging nettle effect and efficacy profiles. Part II: urticae radix. Phytomedicine (2007) 0.96
The pathophysiological function of peroxisome proliferator-activated receptor-gamma in lung-related diseases. Respir Res (2005) 0.96
Pomegranate flower improves cardiac lipid metabolism in a diabetic rat model: role of lowering circulating lipids. Br J Pharmacol (2005) 0.95
Phytopreventative anti-hyperlipidemic effects of gynostemma pentaphyllum in rats. J Pharm Pharm Sci (2005) 0.94
Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model. Drug Dev Ind Pharm (2010) 0.93
Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-kappaB-mediated iNOS protein expression. Nitric Oxide (2003) 0.93
ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1. Curr Neuropharmacol (2008) 0.93
Modulation of diabetic retinopathy pathophysiology by natural medicines through PPAR-γ-related pharmacology. Br J Pharmacol (2012) 0.92
Preventive and Protective Properties of Zingiber officinale (Ginger) in Diabetes Mellitus, Diabetic Complications, and Associated Lipid and Other Metabolic Disorders: A Brief Review. Evid Based Complement Alternat Med (2012) 0.92
Herbal medicines and nutraceuticals for diabetic vascular complications: mechanisms of action and bioactive phytochemicals. Curr Pharm Des (2010) 0.90
Regulation of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase expression by Zingiber officinale in the liver of high-fat diet-fed rats. Basic Clin Pharmacol Toxicol (2009) 0.90
Liposomal nanoparticles control the uptake of ciprofloxacin across respiratory epithelia. Pharm Res (2012) 0.89
Human and mouse mast cells use the tetraspanin CD9 as an alternate interleukin-16 receptor. Blood (2005) 0.88
Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via a PPAR-alpha-dependent pathway. J Biomed Sci (2006) 0.88
Gingerols of Zingiber officinale enhance glucose uptake by increasing cell surface GLUT4 in cultured L6 myotubes. Planta Med (2012) 0.87
Pomegranate flower extract diminishes cardiac fibrosis in Zucker diabetic fatty rats: modulation of cardiac endothelin-1 and nuclear factor-kappaB pathways. J Cardiovasc Pharmacol (2005) 0.87
Protein kinase C modulation of thermo-sensitive transient receptor potential channels: Implications for pain signaling. J Nat Sci Biol Med (2011) 0.86
Modulation of P-glycoprotein-mediated anticancer drug accumulation, cytotoxicity, and ATPase activity by flavonoid interactions. Nutr Cancer (2011) 0.86
Attenuation of Proinflammatory Responses by S-[6]-Gingerol via Inhibition of ROS/NF-Kappa B/COX2 Activation in HuH7 Cells. Evid Based Complement Alternat Med (2013) 0.86
Harpagoside suppresses lipopolysaccharide-induced iNOS and COX-2 expression through inhibition of NF-kappa B activation. J Ethnopharmacol (2005) 0.86
Salacia oblonga improves cardiac fibrosis and inhibits postprandial hyperglycemia in obese Zucker rats. Life Sci (2004) 0.86
Attenuation of liver pro-inflammatory responses by Zingiber officinale via inhibition of NF-kappa B activation in high-fat diet-fed rats. Basic Clin Pharmacol Toxicol (2011) 0.86
Evidence-based toxicity evaluation and scheduling of Chinese herbal medicines. J Ethnopharmacol (2012) 0.86
Chronic obstructive pulmonary disease: patho-physiology, current methods of treatment and the potential for simvastatin in disease management. Expert Opin Drug Deliv (2011) 0.85
A comprehensive review on nettle effect and efficacy profiles, Part I: herba urticae. Phytomedicine (2007) 0.85
Characterization of PXR mediated P-glycoprotein regulation in intestinal LS174T cells. Pharmacol Res (2010) 0.84
Gypenoside XLIX, a naturally occurring gynosaponin, PPAR-alpha dependently inhibits LPS-induced tissue factor expression and activity in human THP-1 monocytic cells. Toxicol Appl Pharmacol (2006) 0.84
Gingerol metabolite and a synthetic analogue Capsarol inhibit macrophage NF-kappaB-mediated iNOS gene expression and enzyme activity. Planta Med (2006) 0.84
Microparticles mediate MRP1 intercellular transfer and the re-templating of intrinsic resistance pathways. Pharmacol Res (2013) 0.84
Cell-derived microparticles: new targets in the therapeutic management of disease. J Pharm Pharm Sci (2013) 0.84
Epithelial profiling of antibiotic controlled release respiratory formulations. Pharm Res (2011) 0.83
Factors influencing the abundance of the side population in a human myeloma cell line. Bone Marrow Res (2011) 0.83
Pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects. Br J Clin Pharmacol (2010) 0.83
Cellular communication via microparticles: role in transfer of multidrug resistance in cancer. Future Oncol (2014) 0.82
Effectiveness of Harpagophytum extracts and clinical efficacy. Phytother Res (2004) 0.82
Methodologies for investigating natural medicines for the treatment of nonalcoholic fatty liver disease (NAFLD). Curr Pharm Biotechnol (2012) 0.82
Lycium barbarum (Goji Berry) extracts and its taurine component inhibit PPAR-γ-dependent gene transcription in human retinal pigment epithelial cells: Possible implications for diabetic retinopathy treatment. Biochem Pharmacol (2011) 0.82
Microparticle drug sequestration provides a parallel pathway in the acquisition of cancer drug resistance. Eur J Pharmacol (2013) 0.81
A novel LXR-alpha activator identified from the natural product Gynostemma pentaphyllum. Biochem Pharmacol (2005) 0.81
Bromelain improves decrease in defecation in postoperative rats: modulation of colonic gene expression of inducible nitric oxide synthase. Life Sci (2005) 0.81
Fabrication of Curcumin Micellar Nanoparticles with Enhanced Anti-Cancer Activity. J Biomed Nanotechnol (2015) 0.80
Gypenoside XLIX, a naturally occurring PPAR-alpha activator, inhibits cytokine-induced vascular cell adhesion molecule-1 expression and activity in human endothelial cells. Eur J Pharmacol (2007) 0.80
The effect of vitamin D3 and ketoconazole combination on VDR-mediated P-gp expression and function in human colon adenocarcinoma cells: implications in drug disposition and resistance. Basic Clin Pharmacol Toxicol (2011) 0.80
Deposition, diffusion and transport mechanism of dry powder microparticulate salbutamol, at the respiratory epithelia. Mol Pharm (2012) 0.80
Ciprofloxacin is actively transported across bronchial lung epithelial cells using a Calu-3 air interface cell model. Antimicrob Agents Chemother (2013) 0.80
Healing the diabetic heart: modulation of cardiometabolic syndrome through peroxisome proliferator activated receptors (PPARs). Curr Mol Pharmacol (2012) 0.80
The small GTPases Rab5 and RalA regulate intracellular traffic of P-glycoprotein. Biochim Biophys Acta (2007) 0.80
(S)-[6]-Gingerol enhances glucose uptake in L6 myotubes by activation of AMPK in response to [Ca2+]i. J Pharm Pharm Sci (2013) 0.79
Compound K modulates fatty acid-induced lipid droplet formation and expression of proteins involved in lipid metabolism in hepatocytes. Liver Int (2013) 0.78
Multiple dosing of simvastatin inhibits airway mucus production of epithelial cells: implications in the treatment of chronic obstructive airway pathologies. Eur J Pharm Biopharm (2013) 0.78
Light-to-moderate ethanol feeding augments AMPK-α phosphorylation and attenuates SREBP-1 expression in the liver of rats. J Pharm Pharm Sci (2013) 0.78
Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines. Oncol Rep (2004) 0.78
Preventative effect of Zingiber officinale on insulin resistance in a high-fat high-carbohydrate diet-fed rat model and its mechanism of action. Basic Clin Pharmacol Toxicol (2014) 0.77
ABCB1 (P-glycoprotein) reduces bacterial attachment to human gastrointestinal LS174T epithelial cells. Eur J Pharmacol (2012) 0.77
Identification of a Calcium Signalling Pathway of S-[6]-Gingerol in HuH-7 Cells. Evid Based Complement Alternat Med (2013) 0.76
Ca2+-ATPase isoforms are expressed in neuroprotection in rat, but not human, neurons. Neuroreport (2003) 0.76
A radioassay for synaptic core complex assembly: screening of herbal extracts for effectors. Anal Biochem (2006) 0.76
Identification and characterisation of the RalA-ERp57 interaction: evidence for GDI activity of ERp57. PLoS One (2012) 0.76
Modification of disodium cromoglycate passage across lung epithelium in vitro via incorporation into polymeric microparticles. AAPS J (2011) 0.76
Salbutamol sulfate absorption across Calu-3 bronchial epithelia cell monolayer is inhibited in the presence of common anionic NSAIDs. J Asthma (2013) 0.75
Chronic pain of spinal origin. Spine (Phila Pa 1976) (2003) 0.75
New methodology and approaches to intracellular lipid transport in atherosclerosis and cardiovascular disease. Curr Pharm Biotechnol (2012) 0.75
Effect of vitamin D3 supplementation on the pharmacokinetics of digoxin--a pilot study. Fundam Clin Pharmacol (2011) 0.75
Proceedings of conference on Mechanism-Based Development of Natural Products for Human Health. J Pharm Pharm Sci (2013) 0.75
An analysis of the therapeutic benefits of genotyping in pediatric hematopoietic stem cell transplantation. Future Oncol (2015) 0.75
Phytopreventative effects of Gynostemma pentaphyllum against acute Indomethacin-induced gastrointestinal and renal toxicity in rats. Phytother Res (2007) 0.75
An ethnopharmacological approach to the preliminary screening of native Australian herbal medicines for anticancer activity. J Complement Integr Med (2015) 0.75