Published in Trends Genet on October 01, 1992
Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev (2000) 3.85
BMP4 is essential for lens induction in the mouse embryo. Genes Dev (1998) 2.62
rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina. Proc Natl Acad Sci U S A (1997) 2.29
Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development. Genes Dev (2001) 2.18
Generation of functional eyes from pluripotent cells. PLoS Biol (2009) 1.98
Genetic and epigenetic mechanisms of gene regulation during lens development. Prog Retin Eye Res (2007) 1.56
Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus. PLoS Biol (2004) 1.52
Homozygous nonsense mutation in the FOXE3 gene as a cause of congenital primary aphakia in humans. Am J Hum Genet (2006) 1.40
Convergence of a head-field selector Otx2 and Notch signaling: a mechanism for lens specification. Development (2007) 1.33
Squid Pax-6 and eye development. Proc Natl Acad Sci U S A (1997) 1.31
The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation. Dev Biol (2009) 1.25
Epigenetic regulatory mechanisms in vertebrate eye development and disease. Heredity (Edinb) (2010) 1.16
A complex array of positive and negative elements regulates the chicken alpha A-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins. Mol Cell Biol (1994) 1.15
Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene. Proc Natl Acad Sci U S A (1995) 1.11
Fibroblast growth factor receptor 1 (Fgfr1) is not essential for lens fiber differentiation in mice. Mol Vis (2006) 1.08
The cellular and molecular mechanisms of vertebrate lens development. Development (2014) 1.04
Photoinduction of flower identity in vegetatively biased primordia. Plant Cell (1998) 1.01
Building the developmental oculome: systems biology in vertebrate eye development and disease. Wiley Interdiscip Rev Syst Biol Med (2010) 0.97
Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300. Nucleic Acids Res (2013) 0.95
Eyes absent: a gene family found in several metazoan phyla. Mamm Genome (1997) 0.94
Functions of crystallins in and out of lens: roles in elongated and post-mitotic cells. Prog Biophys Mol Biol (2014) 0.89
Xenopus gamma-crystallin gene expression: evidence that the gamma-crystallin gene family is transcribed in lens and nonlens tissues. Mol Cell Biol (1994) 0.87
The lens-regenerating competence in the outer cornea and epidermis of larval Xenopus laevis is related to pax6 expression. J Anat (2008) 0.81
LP2, a differentiation-associated lipid-binding protein expressed in bovine lens. Biochem J (1996) 0.80
The optic vesicle promotes cornea to lens transdifferentiation in larval Xenopus laevis. J Anat (2008) 0.76
Early stages of induction of anterior head ectodermal properties in Xenopus embryos are mediated by transcriptional cofactor ldb1. Dev Dyn (2014) 0.75
Defining progressive stages in the commitment process leading to embryonic lens formation. Genesis (2012) 0.75
Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. PLoS One (2016) 0.75
The molecular mechanisms underlying lens fiber elongation. Exp Eye Res (2016) 0.75
Signaling and Gene Regulatory Networks in Mammalian Lens Development. Trends Genet (2017) 0.75