Published in Neurology on February 10, 2004
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Cerebrospinal fluid Alzheimer's biomarker profiles in CNS infections. J Neurol (2012) 0.99
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Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis. J Neuroinflammation (2011) 0.81
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Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat Neurosci (2007) 6.23
Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain (2005) 5.29
The immunopathology of multiple sclerosis: an overview. Brain Pathol (2007) 4.23
Inflammatory cortical demyelination in early multiple sclerosis. N Engl J Med (2011) 4.02
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity (2008) 3.67
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway. Brain (2011) 3.38
Epstein-Barr virus infection is not a characteristic feature of multiple sclerosis brain. Brain (2009) 3.04
A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis. Nat Med (2011) 3.00
Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange. Lancet (2005) 2.68
CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain (2009) 2.59
Autologous haematopoietic stem cell transplantation fails to stop demyelination and neurodegeneration in multiple sclerosis. Brain (2007) 2.46
Remyelination is extensive in a subset of multiple sclerosis patients. Brain (2006) 2.43
Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci (2011) 2.31
Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. Brain (2002) 2.27
Microglial phenotype: is the commitment reversible? Trends Neurosci (2006) 2.18
Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis. J Clin Invest (2006) 2.17
Tissue preconditioning may explain concentric lesions in Baló's type of multiple sclerosis. Brain (2005) 2.07
Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis. Proc Natl Acad Sci U S A (2006) 1.79
Neuronal injury in bacterial meningitis: mechanisms and implications for therapy. Trends Neurosci (2002) 1.78
Mechanisms of acute axonal degeneration in the optic nerve in vivo. Proc Natl Acad Sci U S A (2010) 1.70
Association between pathological and MRI findings in multiple sclerosis. Lancet Neurol (2012) 1.70
Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosis. Neurology (2012) 1.67
Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice. Brain (2006) 1.63
Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage. Brain (2007) 1.63
Acute effects of intracranial hypertension and ARDS on pulmonary and neuronal damage: a randomized experimental study in pigs. Intensive Care Med (2011) 1.57
Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases. J Neuropathol Exp Neurol (2003) 1.55
PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation. Infect Immun (2005) 1.54
Microglia inflict delayed brain injury after subarachnoid hemorrhage. Acta Neuropathol (2015) 1.51
Widespread demyelination in the cerebellar cortex in multiple sclerosis. Brain Pathol (2007) 1.49
Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs. J Clin Invest (2008) 1.44
Iron and neurodegeneration in the multiple sclerosis brain. Ann Neurol (2013) 1.43
Extensive cortical remyelination in patients with chronic multiple sclerosis. Brain Pathol (2007) 1.41
IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system. Brain (2011) 1.37
A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination. Brain (2006) 1.35
BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells? Brain (2002) 1.33
Immunological and clinical consequences of treating a patient with natalizumab. Mult Scler (2011) 1.33
Targeting experimental autoimmune encephalomyelitis lesions to a predetermined axonal tract system allows for refined behavioral testing in an animal model of multiple sclerosis. Am J Pathol (2004) 1.31
Cortical pathology in multiple sclerosis. Curr Opin Neurol (2008) 1.31
Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase. Neurobiol Dis (2002) 1.28
Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin. J Neuroimmunol (2011) 1.27
T cell-dependence of Lassa fever pathogenesis. PLoS Pathog (2010) 1.25
Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone. Antimicrob Agents Chemother (2003) 1.25
Primary hypophysitis: clinical-pathological correlations. Eur J Endocrinol (2006) 1.25
Remodeling of axonal connections contributes to recovery in an animal model of multiple sclerosis. J Exp Med (2004) 1.25
Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis. Infect Immun (2002) 1.23
Inflammation, demyelination, and degeneration - recent insights from MS pathology. Biochim Biophys Acta (2010) 1.20
Multicontrast MRI of remyelination in the central nervous system. NMR Biomed (2005) 1.19
A new paraclinical CSF marker for hypoxia-like tissue damage in multiple sclerosis lesions. Brain (2003) 1.18
Toll-like receptor stimulation enhances phagocytosis and intracellular killing of nonencapsulated and encapsulated Streptococcus pneumoniae by murine microglia. Infect Immun (2009) 1.18
Dose-dependent activation of microglial cells by Toll-like receptor agonists alone and in combination. J Neuroimmunol (2004) 1.16
Therapeutic decisions in multiple sclerosis: moving beyond efficacy. JAMA Neurol (2013) 1.16
Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels, inflammatory demyelination and acute axonal damage in mice with experimental autoimmune encephalomyelitis. J Neuroimmunol (2010) 1.15
Cell type-specific Nrf2 expression in multiple sclerosis lesions. Acta Neuropathol (2015) 1.15
Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures. J Neurochem (2005) 1.14
Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease. Neurobiol Aging (2008) 1.12
Feasibility of prehospital teleconsultation in acute stroke--a pilot study in clinical routine. PLoS One (2012) 1.12
Pathology of immune reconstitution inflammatory syndrome in multiple sclerosis with natalizumab-associated progressive multifocal leukoencephalopathy. Acta Neuropathol (2011) 1.12
TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis. Nat Med (2012) 1.11
Negative impact of statins on oligodendrocytes and myelin formation in vitro and in vivo. J Neurosci (2008) 1.10
Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons. Acta Neuropathol (2013) 1.08
Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia. Glia (2012) 1.08
Specific central nervous system recruitment of HLA-G(+) regulatory T cells in multiple sclerosis. Ann Neurol (2009) 1.08
Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ cells. J Immunol (2005) 1.06
Assessment of lesion pathology in a new animal model of MS by multiparametric MRI and DTI. Neuroimage (2011) 1.06
Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation. Neurobiol Dis (2007) 1.05
Molecular changes in white matter adjacent to an active demyelinating lesion in early multiple sclerosis. Brain Pathol (2008) 1.02
Wallerian degeneration: a major component of early axonal pathology in multiple sclerosis. Brain Pathol (2010) 1.02
Differential upregulation of heme oxygenase-1 (HSP32) in glial cells after oxidative stress and in demyelinating disorders. J Mol Neurosci (2007) 1.02
Cerebral involvement in axonal Charcot-Marie-Tooth neuropathy caused by mitofusin2 mutations. J Neurol (2008) 1.01
Myelin-phagocytosing macrophages in isolated sciatic and optic nerves reveal a unique reactive phenotype. Glia (2008) 1.00
Neuronal apoptosis in the dentate gyrus in humans with subarachnoid hemorrhage and cerebral hypoxia. Brain Pathol (2002) 1.00
Differential regulation of Toll-like receptor mRNAs in experimental murine central nervous system infections. Neurosci Lett (2003) 0.99
The role of cytokines and adhesion molecules in axon degeneration after peripheral nerve axotomy: a study in different knockout mice. Brain Res (2003) 0.99
Diagnosis of inflammatory demyelination in biopsy specimens: a practical approach. Acta Neuropathol (2008) 0.99
Nogo-A is a reliable oligodendroglial marker in adult human and mouse CNS and in demyelinated lesions. J Neuropathol Exp Neurol (2007) 0.98
Axonal loss and neurofilament phosphorylation changes accompany lesion development and clinical progression in multiple sclerosis. Brain Pathol (2011) 0.98
CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS. Brain Behav Immun (2010) 0.98
In toxic demyelination oligodendroglial cell death occurs early and is FAS independent. Neurobiol Dis (2009) 0.98
Matrix metalloproteinase-9 deficiency impairs host defense mechanisms against Streptococcus pneumoniae in a mouse model of bacterial meningitis. Neurosci Lett (2003) 0.97
Selective neuronal vulnerability following mild focal brain ischemia in the mouse. Brain Pathol (2003) 0.96
TRPM3 is expressed in sphingosine-responsive myelinating oligodendrocytes. J Neurochem (2010) 0.96
Atypical chronic lymphocytic inflammation with pontocerebellar perivascular enhancement responsive to steroids (CLIPPERS), primary angiitis of the CNS mimicking CLIPPERS or overlap syndrome? A case report. J Neurol Sci (2012) 0.95
Natalizumab use in pediatric multiple sclerosis. Arch Neurol (2008) 0.94
Early loss of oligodendrocytes in human and experimental neuromyelitis optica lesions. Acta Neuropathol (2013) 0.94
Extensive acute axonal damage in pediatric multiple sclerosis lesions. Ann Neurol (2015) 0.94
Favourable response to plasma exchange in tumefactive CNS demyelination with delayed B-cell response. Mult Scler (2011) 0.93
Intracerebral human regulatory T cells: analysis of CD4+ CD25+ FOXP3+ T cells in brain lesions and cerebrospinal fluid of multiple sclerosis patients. PLoS One (2011) 0.93
TAT-Bcl-x(L) improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemia. Neurobiol Dis (2009) 0.92
Increased activin levels in cerebrospinal fluid of rabbits with bacterial meningitis are associated with activation of microglia. J Neurochem (2003) 0.92
Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis. Ann Neurol (2012) 0.92
Oligodendrocyte injury in multiple sclerosis: a role for p53. J Neurochem (2003) 0.92
Rapid microtubule bundling and stabilization by the Streptococcus pneumoniae neurotoxin pneumolysin in a cholesterol-dependent, non-lytic and Src-kinase dependent manner inhibits intracellular trafficking. Mol Microbiol (2008) 0.92
Intradural, extramedullary spinal sarcoidosis: report of a rare case and review of the literature. Spine J (2006) 0.92
Multiple sclerosis - remyelination failure as a cause of disease progression. Histol Histopathol (2012) 0.91
Streptococcus pneumoniae Infection aggravates experimental autoimmune encephalomyelitis via Toll-like receptor 2. Infect Immun (2006) 0.91
Pathologic heterogeneity persists in early active multiple sclerosis lesions. Ann Neurol (2014) 0.91
Isolated pituitary granuloma by atypical Mycobacterium in a nonimmunosuppressed woman. Clin Endocrinol (Oxf) (2002) 0.91