Published in Sci STKE on February 03, 2004
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The role of the TRP channel NompC in Drosophila larval and adult locomotion. Neuron (2010) 2.44
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Molecular pathways mediating mechanical signaling in bone. Gene (2005) 2.17
Molecular dynamics study of gating in the mechanosensitive channel of small conductance MscS. Biophys J (2004) 2.00
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TRP channels and mechanosensory transduction: insights into the arterial myogenic response. Pflugers Arch (2008) 1.24
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The mechanobiology of brain function. Nat Rev Neurosci (2012) 1.15
Disulfide trapping the mechanosensitive channel MscL into a gating-transition state. Biophys J (2006) 1.13
Surface changes of the mechanosensitive channel MscS upon its activation, inactivation, and closing. Biophys J (2005) 1.11
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Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators. Mol Biol Cell (2012) 1.10
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OCAM: a new tool for studying the oligomeric diversity of MscL channels. Protein Sci (2011) 1.04
Bubbles, gating, and anesthetics in ion channels. Biophys J (2008) 1.02
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Heterologously expressed fungal transient receptor potential channels retain mechanosensitivity in vitro and osmotic response in vivo. Eur Biophys J (2005) 0.94
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Bidirectional extracellular matrix signaling during tissue morphogenesis. Cytokine Growth Factor Rev (2009) 0.93
Lung ischemia: a model for endothelial mechanotransduction. Cell Biochem Biophys (2008) 0.91
Mechanical sensitivity of Piezo1 ion channels can be tuned by cellular membrane tension. Elife (2015) 0.90
Lysophosphatidyl choline modulates mechanosensitive L-type Ca2+ current in circular smooth muscle cells from human jejunum. Am J Physiol Gastrointest Liver Physiol (2009) 0.88
MscS-like mechanosensitive channels in plants and microbes. Biochemistry (2013) 0.88
Membrane tension, lipid adaptation, conformational changes, and energetics in MscL gating. Biophys J (2011) 0.85
Cell mechanosensitivity: mechanical properties and interaction with gravitational field. Biomed Res Int (2012) 0.84
Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3. Nat Commun (2016) 0.83
A virtual hair cell, II: evaluation of mechanoelectric transduction parameters. Biophys J (2007) 0.83
Energetics of gating MscS by membrane tension in azolectin liposomes and giant spheroplasts. Channels (Austin) (2014) 0.83
Cell biology of mechanotransduction in inner-ear hair cells. F1000 Biol Rep (2009) 0.83
Crocodylians evolved scattered multi-sensory micro-organs. Evodevo (2013) 0.82
Effect of high hydrostatic pressure on the bacterial mechanosensitive channel MscS. Eur Biophys J (2005) 0.82
Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy. Oncogene (2015) 0.81
The effect of local bending on gating of MscL using a representative volume element and finite element simulation. Channels (Austin) (2014) 0.81
Cadherin-11 regulates both mesenchymal stem cell differentiation into smooth muscle cells and the development of contractile function in vivo. J Cell Sci (2014) 0.80
Localized force application reveals mechanically sensitive domains of Piezo1. Nat Commun (2016) 0.79
Modulation of channel activity and gadolinium block of MscL by static magnetic fields. Eur Biophys J (2006) 0.79
Directed stem cell differentiation: the role of physical forces. Cell Commun Adhes (2010) 0.79
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Mechanical signaling in reproductive tissues: mechanisms and importance. Reprod Sci (2014) 0.77
Interactions of the Mechanosensitive Channels with Extracellular Matrix, Integrins, and Cytoskeletal Network in Osmosensation. Front Mol Neurosci (2017) 0.75
Effects of a skin-massaging device on the ex-vivo expression of human dermis proteins and in-vivo facial wrinkles. PLoS One (2017) 0.75
"INTEGRINating" the connexin hemichannel function in bone osteocytes through the action of integrin α5. Commun Integr Biol (2012) 0.75
Response of the human detrusor to stretch is regulated by TREK-1, a two-pore-domain (K2P) mechano-gated potassium channel. J Physiol (2014) 0.75
A Review on Brain Stimulation Using Low Intensity Focused Ultrasound. Basic Clin Neurosci (2016) 0.75
TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron (2006) 8.57
Lighting up the senses: FM1-43 loading of sensory cells through nonselective ion channels. J Neurosci (2003) 4.28
In search of the hair-cell gating spring elastic properties of ankyrin and cadherin repeats. Structure (2005) 3.36
A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells. Cell (2002) 3.34
An ion channel essential for sensing chemical damage. J Neurosci (2007) 3.03
Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science (2005) 2.81
TRP channels in mechanosensation: direct or indirect activation? Nat Rev Neurosci (2007) 2.81
Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia. Nature (2012) 2.52
The micromachinery of mechanotransduction in hair cells. Annu Rev Neurosci (2007) 2.17
TRPA1 modulates mechanotransduction in cutaneous sensory neurons. J Neurosci (2009) 2.07
Essential role of retinoblastoma protein in mammalian hair cell development and hearing. Proc Natl Acad Sci U S A (2006) 1.78
The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli. Gastroenterology (2009) 1.78
TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. Nat Neurosci (2011) 1.67
Ca2+ changes the force sensitivity of the hair-cell transduction channel. Biophys J (2005) 1.48
The PDZ domain protein PICK1 and the sodium channel BNaC1 interact and localize at mechanosensory terminals of dorsal root ganglion neurons and dendrites of central neurons. J Biol Chem (2001) 1.48
Vascular defects and sensorineural deafness in a mouse model of Norrie disease. J Neurosci (2002) 1.44
Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction. Nature (2012) 1.41
Structural determinants of cadherin-23 function in hearing and deafness. Neuron (2010) 1.36
Effects of genetic variations in the dystonia protein torsinA: identification of polymorphism at residue 216 as protein modifier. Hum Mol Genet (2006) 1.35
TRP channels in mechanosensation. Curr Opin Neurobiol (2005) 1.25
Mutant sodium channel for tumor therapy. Mol Ther (2009) 1.22
Hearing: tightrope act. Nature (2004) 1.16
The early onset dystonia protein torsinA interacts with kinesin light chain 1. J Biol Chem (2004) 1.16
Sliding adhesion confers coherent motion to hair cell stereocilia and parallel gating to transduction channels. J Neurosci (2010) 1.12
Burning cold: involvement of TRPA1 in noxious cold sensation. J Gen Physiol (2009) 1.11
An inner ear gene expression database. J Assoc Res Otolaryngol (2002) 0.94
The α1 subunit of nicotinic acetylcholine receptors in the inner ear: transcriptional regulation by ATOH1 and co-expression with the γ subunit in hair cells. J Neurochem (2007) 0.89
Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells. FEBS Lett (2007) 0.86
Noddy, a mouse harboring a missense mutation in protocadherin-15, reveals the impact of disrupting a critical interaction site between tip-link cadherins in inner ear hair cells. J Neurosci (2013) 0.85
Stringing the fiddle: the inner ear's two-part invention. Nat Neurosci (2007) 0.84
Understanding inner ear development with gene expression profiling. J Neurobiol (2002) 0.79
The force be with you: a mechanoreceptor channel in proprioception and touch. Neuron (2010) 0.76
A gradient of single-channel conductance in the cochlea: tuning the cochlea's strings? Neuron (2003) 0.75
Sensory systems: from molecules to percepts. Curr Opin Neurobiol (2008) 0.75