Published in J Med Chem on February 26, 2004
Regulation of zebrafish sleep and arousal states: current and prospective approaches. Front Neural Circuits (2013) 0.84
Unique interaction pattern for a functionally biased ghrelin receptor agonist. J Biol Chem (2011) 0.81
Truncated Orexin Peptides: Structure-Activity Relationship Studies. ACS Med Chem Lett (2013) 0.77
Crucial role of the orexin-B C-terminus in the induction of OX1 receptor-mediated apoptosis: analysis by alanine scanning, molecular modelling and site-directed mutagenesis. Br J Pharmacol (2015) 0.76
Modeling of the OX1R-orexin-A complex suggests two alternative binding modes. BMC Struct Biol (2015) 0.75
Corticotropin releasing factor (CRF) receptor signaling in the central nervous system: new molecular targets. CNS Neurol Disord Drug Targets (2006) 1.97
International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands. Pharmacol Rev (2003) 1.79
GPR39 signaling is stimulated by zinc ions but not by obestatin. Endocrinology (2006) 1.60
Role of CRF receptor signaling in stress vulnerability, anxiety, and depression. Ann N Y Acad Sci (2009) 1.59
Isotope-labeled cross-linkers and Fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex. J Am Soc Mass Spectrom (2006) 1.31
Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. J Exp Med (2008) 1.27
Neuropeptide Y stimulates neuronal precursor proliferation in the post-natal and adult dentate gyrus. J Neurochem (2005) 1.26
Blocking melanin-concentrating hormone MCH1 receptor affects rat sleep-wake architecture. Eur J Pharmacol (2007) 1.13
Carboxyl-terminal and intracellular loop sites for CRF1 receptor phosphorylation and beta-arrestin-2 recruitment: a mechanism regulating stress and anxiety responses. Am J Physiol Regul Integr Comp Physiol (2007) 1.12
The anti-epileptic actions of neuropeptide Y in the hippocampus are mediated by Y and not Y receptors. Eur J Neurosci (2005) 1.10
Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers. Biophys J (2008) 1.10
Peptide drugs to target G protein-coupled receptors. Trends Pharmacol Sci (2010) 1.09
In vivo characterization of high Basal signaling from the ghrelin receptor. Endocrinology (2009) 1.08
Decoding the entry of two novel cell-penetrating peptides in HeLa cells: lipid raft-mediated endocytosis and endosomal escape. Biochemistry (2005) 1.08
Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors. Biol Chem (2010) 1.08
Characterization of the interaction of interleukin-8 with hyaluronan, chondroitin sulfate, dermatan sulfate and their sulfated derivatives by spectroscopy and molecular modeling. Glycobiology (2011) 1.07
Homodimerization of neuropeptide y receptors investigated by fluorescence resonance energy transfer in living cells. J Biol Chem (2003) 1.05
Expressed protein ligation. Method and applications. Eur J Biochem (2004) 1.04
Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior. J Biol Chem (2008) 1.02
Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine. Clin Sci (Lond) (2008) 1.00
Artificial chemokines: combining chemistry and molecular biology for the elucidation of interleukin-8 functionality. J Am Chem Soc (2008) 1.00
The third intracellular loop stabilizes the inactive state of the neuropeptide Y1 receptor. J Biol Chem (2008) 1.00
Biochemical characterisation and genetic analysis of aureocin A53, a new, atypical bacteriocin from Staphylococcus aureus. J Mol Biol (2002) 0.98
A Y2 receptor mimetic aptamer directed against neuropeptide Y. J Biol Chem (2001) 0.98
Metabolic cleavage of cell-penetrating peptides in contact with epithelial models: human calcitonin (hCT)-derived peptides, Tat(47-57) and penetratin(43-58). Biochem J (2004) 0.98
Blockade of neuropeptide Y(2) receptors and suppression of NPY's anti-epileptic actions in the rat hippocampal slice by BIIE0246. Br J Pharmacol (2002) 0.97
Agonist induced receptor internalization of neuropeptide Y receptor subtypes depends on third intracellular loop and C-terminus. Cell Signal (2008) 0.97
Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism. J Biol Chem (2007) 0.96
Glutamate release by neurons evokes a purinergic inhibitory mechanism of osmotic glial cell swelling in the rat retina: activation by neuropeptide Y. J Neurosci Res (2006) 0.96
Corticotropin-releasing factor receptor antagonists in affective disorders and drug dependence-- an update. CNS Neurol Disord Drug Targets (2006) 0.96
Molecular mechanisms of corticotropin-releasing factor receptor-induced calcium signaling. Mol Pharmacol (2008) 0.95
Type I Arginine Methyltransferases PRMT1 and PRMT-3 Act Distributively. J Biol Chem (2009) 0.95
Long-acting lipidated analogue of human pancreatic polypeptide is slowly released into circulation. J Med Chem (2011) 0.94
Therapeutic potential of group III metabotropic glutamate receptors. Curr Med Chem (2008) 0.94
Neuropeptide Y receptors: how to get subtype selectivity. Front Endocrinol (Lausanne) (2013) 0.94
Peptides and peptide conjugates: therapeutics on the upward path. Future Med Chem (2012) 0.93
Electron paramagnetic resonance backbone dynamics studies on spin-labelled neuropeptide Y analogues. J Pept Sci (2002) 0.92
Illuminating the life of GPCRs. Cell Commun Signal (2009) 0.92
Chemical and biological characterization of new Re(CO)3/[99mTc](CO)3 bombesin analogues. Nucl Med Biol (2006) 0.91
Proteome analysis to study signal transduction of G protein-coupled receptors. Pharmacol Ther (2006) 0.91
Mediation of corticotropin releasing factor type 1 receptor phosphorylation and desensitization by protein kinase C: a possible role in stress adaptation. J Pharmacol Exp Ther (2003) 0.90
Multiple NPY receptors Inhibit GABA(A) synaptic responses of rat medial parvocellular effector neurons in the hypothalamic paraventricular nucleus. Endocrinology (2002) 0.89
Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands. J Biol Chem (2007) 0.89
Molecular and cell signaling targets for PTSD pathophysiology and pharmacotherapy. Neuropharmacology (2011) 0.88
Neuropeptide Y receptors: ligand binding and trafficking suggest novel approaches in drug development. J Pept Sci (2011) 0.88
Ghrelin--a novel generation of anti-obesity drug: design, pharmacomodulation and biological activity of ghrelin analogues. J Pept Sci (2009) 0.88
Ghrelin receptor: high constitutive activity and methods for developing inverse agonists. Methods Enzymol (2010) 0.88
Pharmacological characterization of JNJ-40068782, a new potent, selective, and systemically active positive allosteric modulator of the mGlu2 receptor and its radioligand [3H]JNJ-40068782. J Pharmacol Exp Ther (2013) 0.88
Dimerization of adiponectin receptor 1 is inhibited by adiponectin. J Cell Sci (2010) 0.88
Ligand-induced internalization and recycling of the human neuropeptide Y2 receptor is regulated by its carboxyl-terminal tail. J Biol Chem (2010) 0.88
Molecular recognition of the NPY hormone family by their receptors. Nutrition (2008) 0.87
In vitro and in vivo evaluation of a 99mTc(I)-labeled bombesin analogue for imaging of gastrin releasing peptide receptor-positive tumors. Nucl Med Biol (2002) 0.87
Towards improved receptor targeting: anterograde transport, internalization and postendocytic trafficking of neuropeptide Y receptors. Biol Chem (2013) 0.86
A novel, biased-like SDF-1 derivative acts synergistically with starPEG-based heparin hydrogels and improves eEPC migration in vitro. J Control Release (2012) 0.86
Targeted tumor diagnosis and therapy with peptide hormones as radiopharmaceuticals. Anticancer Agents Med Chem (2008) 0.86
Novel chemically modified analogues of neuropeptide Y for tumor targeting. Bioconjug Chem (2008) 0.85
Central NPY receptor-mediated alteration of heart rate dynamics in mice during expression of fear conditioned to an auditory cue. Regul Pept (2004) 0.85
Analogues of neuropeptide Y containing beta-aminocyclopropane carboxylic acids are the shortest linear peptides that are selective for the Y1 receptor. Angew Chem Int Ed Engl (2003) 0.85
Novel hexahydrospiro[piperidine-4,1'-pyrrolo[3,4-c]pyrroles]: highly selective small-molecule nociceptin/orphanin FQ receptor agonists. J Med Chem (2003) 0.85
Tracking of human Y receptors in living cells--a fluorescence approach. Peptides (2007) 0.85
Structure-activity studies of RFamide peptides reveal subtype-selective activation of neuropeptide FF1 and FF2 receptors. ChemMedChem (2011) 0.84
Breast-cancer diagnosis by neuropeptide Y analogues: from synthesis to clinical application. Angew Chem Int Ed Engl (2010) 0.84
Large scale modification of biomolecules using immobilized sortase A from Staphylococcus aureus. Bioorg Med Chem (2013) 0.84
Vaspin inhibits kallikrein 7 by serpin mechanism. Cell Mol Life Sci (2013) 0.84
Developing novel hCT derived cell-penetrating peptides with improved metabolic stability. Biochim Biophys Acta (2005) 0.84
Cell-type specific calcium signaling by corticotropin-releasing factor type 1 (CRF1) and 2a (CRF2(a)) receptors: phospholipase C-mediated responses in human embryonic kidney 293 but not SK-N-MC neuroblastoma cells. Biochem Pharmacol (2004) 0.84
Cellular uptake but low permeation of human calcitonin-derived cell penetrating peptides and Tat(47-57) through well-differentiated epithelial models. Pharm Res (2004) 0.84
Identification of the key residue of calcitonin gene related peptide (CGRP) 27-37 to obtain antagonists with picomolar affinity at the CGRP receptor. J Med Chem (2006) 0.84
Processing, signaling, and physiological function of chemerin. IUBMB Life (2014) 0.83
Comparative analysis of the signaling capabilities of the insulin receptor-related receptor. Biochem Biophys Res Commun (2005) 0.83
The SK-N-MC cell line expresses an orexin binding site different from recombinant orexin 1-type receptor. Eur J Biochem (2002) 0.83
Protein kinase CK2 interacts with adiponectin receptor 1 and participates in adiponectin signaling. Cell Signal (2009) 0.83
Corticotropin releasing factor-induced ERK phosphorylation in AtT20 cells occurs via a cAMP-dependent mechanism requiring EPAC2. Neuropharmacology (2009) 0.83
Membrane interaction of neuropeptide Y detected by EPR and NMR spectroscopy. Biochim Biophys Acta (2005) 0.83
Specifically immobilised aldo/keto reductase AKR1A1 shows a dramatic increase in activity relative to the randomly immobilised enzyme. Chembiochem (2007) 0.83
Neuropeptide Y suppresses absence seizures in a genetic rat model primarily through effects on Y receptors. Eur J Neurosci (2007) 0.83
Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y2 receptor ligands. Eur J Pharmacol (2006) 0.83
Nociceptive and behavioural sensitisation by protein kinase Cepsilon signalling in the CNS. J Neurochem (2007) 0.83
Presence of neuropeptide Y and the Y1 receptor in the plasma membrane and nuclear envelope of human endocardial endothelial cells: modulation of intracellular calcium. Can J Physiol Pharmacol (2003) 0.83
Pyridone dipeptide backbone scan to elucidate structural properties of a flexible peptide segment. J Am Chem Soc (2008) 0.82
Semisynthesis and application of carboxyfluorescein-labelled biologically active human interleukin-8. Biol Chem (2003) 0.82
GPC receptors and not ligands decide the binding mode in neuropeptide Y multireceptor/multiligand system. Biochemistry (2008) 0.82
Strongly altered receptor binding properties in PP and NPY chimeras are accompanied by changes in structure and membrane binding. Biochemistry (2005) 0.82
Modulation of group II metabotropic glutamate receptor (mGlu2) elicits common changes in rat and mice sleep-wake architecture. Eur J Pharmacol (2008) 0.82
Nano-high-performance liquid chromatography in combination with nano-electrospray ionization Fourier transform ion-cyclotron resonance mass spectrometry for proteome analysis. Rapid Commun Mass Spectrom (2003) 0.82
Identification of neuropeptide Y cleavage products in human blood to improve metabolic stability. Biopolymers (2007) 0.82
Calcitonin-derived peptide carriers: mechanisms and application. Adv Drug Deliv Rev (2007) 0.82
A novel type of macrothrombocytopenia associated with a defect in α2,3-sialylation. Am J Pathol (2011) 0.82
Localization of novel adiponectin receptor constructs. J Recept Signal Transduct Res (2006) 0.81
Expressed enzymatic ligation for the semisynthesis of chemically modified proteins. Angew Chem Int Ed Engl (2003) 0.81
An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor. J Med Chem (2012) 0.81
First selective agonist of the neuropeptide Y1-receptor with reduced size. J Pept Sci (2009) 0.81
Expression, binding, and signaling properties of CRF2(a) receptors endogenously expressed in human retinoblastoma Y79 cells: passage-dependent regulation of functional receptors. J Neurochem (2007) 0.81
Molecular tools to characterize adiponectin activity. Vitam Horm (2012) 0.81
Urocortins of the South African clawed frog, Xenopus laevis: conservation of structure and function in tetrapod evolution. Endocrinology (2005) 0.81
Unique interaction pattern for a functionally biased ghrelin receptor agonist. J Biol Chem (2011) 0.81
Agonists for neuropeptide Y receptors Y1 and Y5 stimulate different phases of feeding in guinea pigs. Br J Pharmacol (2003) 0.81