Published in Toxicol Sci on February 19, 2004
Tissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice. Am J Physiol Gastrointest Liver Physiol (2009) 1.07
Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis. Clin Exp Gastroenterol (2008) 1.02
Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines. J Biol Chem (2008) 1.01
Bile acid dysregulation, gut dysbiosis, and gastrointestinal cancer. Exp Biol Med (Maywood) (2014) 0.90
Role of hepatic transporters in prevention of bile acid toxicity after partial hepatectomy in mice. Am J Physiol Gastrointest Liver Physiol (2009) 0.90
Deoxycholate, an endogenous cytotoxin/genotoxin, induces the autophagic stress-survival pathway: implications for colon carcinogenesis. J Toxicol (2009) 0.88
Molecular mechanisms of ursodeoxycholic acid toxicity & side effects: ursodeoxycholic acid freezes regeneration & induces hibernation mode. Int J Mol Sci (2012) 0.81
Bile acids as constituents for dental composites: in vitro cytotoxicity of (meth)acrylate and other ester derivatives of bile acids. J R Soc Interface (2007) 0.75
Possible Involvement of Nitric Oxide in Enhanced Liver Injury and Fibrogenesis during Cholestasis in Cytoglobin-deficient Mice. Sci Rep (2017) 0.75
The Impact of Sterile Inflammation in Acute Liver Injury. J Clin Transl Res (2017) 0.75
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab (2012) 3.69
Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress. Toxicol Appl Pharmacol (2006) 2.80
Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis. Free Radic Biol Med (2011) 2.34
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy. Aging (Albany NY) (2010) 2.27
Structure-activity relationships and human relevance for perfluoroalkyl acid-induced transcriptional activation of peroxisome proliferation in liver cell cultures. Toxicol Sci (2009) 1.62
Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs. Antimicrob Agents Chemother (2007) 1.27
Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action. Toxicol Sci (2007) 1.19
Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS). Toxicology (2007) 1.15
Perfluorooctanoate, perflourooctanesulfonate, and N-ethyl perfluorooctanesulfonamido ethanol; peroxisome proliferation and mitochondrial biogenesis. Toxicol Lett (2002) 1.15
Assessment of the toxicity of silver nanoparticles in vitro: a mitochondrial perspective. Toxicol In Vitro (2011) 1.10
Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets. Cell Biol Toxicol (2008) 1.08
Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis. Biochim Biophys Acta (2011) 1.05
Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity. Toxicol Appl Pharmacol (2004) 1.04
Calcium oxalate monohydrate, a metabolite of ethylene glycol, is toxic for rat renal mitochondrial function. Toxicol Sci (2004) 1.04
Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis. Toxicol Appl Pharmacol (2007) 1.03
Diabetes and mitochondrial bioenergetics: alterations with age. J Biochem Mol Toxicol (2003) 0.96
Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats. FEBS Lett (2003) 0.96
Persistent alterations to the gene expression profile of the heart subsequent to chronic Doxorubicin treatment. Cardiovasc Toxicol (2007) 0.95
Gestational and lactational exposure to potassium perfluorooctanesulfonate (K+PFOS) in rats: toxicokinetics, thyroid hormone status, and related gene expression. Reprod Toxicol (2009) 0.91
Differentiation-dependent doxorubicin toxicity on H9c2 cardiomyoblasts. Cardiovasc Toxicol (2012) 0.91
Negative bias from analog methods used in the analysis of free thyroxine in rat serum containing perfluorooctanesulfonate (PFOS). Toxicology (2007) 0.90
Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts. Cancer Chemother Pharmacol (2009) 0.89
Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death. BMC Cell Biol (2007) 0.89
Fatty liver and ischemia/reperfusion: are there drugs able to mitigate injury? Curr Med Chem (2011) 0.88
Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy. Toxicology (2010) 0.88
Diabetes induces metabolic adaptations in rat liver mitochondria: role of coenzyme Q and cardiolipin contents. Biochim Biophys Acta (2003) 0.88
Prevention of I/R injury in fatty livers by ischemic preconditioning is associated with increased mitochondrial tolerance: the key role of ATPsynthase and mitochondrial permeability transition. Transpl Int (2009) 0.87
Biosensor plates detect mitochondrial physiological regulators and mutations in vivo. Anal Biochem (2008) 0.87
Indirubin-3'-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction. Toxicol Appl Pharmacol (2008) 0.87
Direct effects of nucleoside reverse transcriptase inhibitors on rat cardiac mitochondrial bioenergetics. Mitochondrion (2004) 0.86
Mitochondrially mediated synergistic cell killing by bile acids. Biochim Biophys Acta (2003) 0.86
Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression. Mitochondrion (2008) 0.86
Indirubin-3'-oxime prevents hepatic I/R damage by inhibiting GSK-3beta and mitochondrial permeability transition. Mitochondrion (2010) 0.86
Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism. Toxicol Lett (2002) 0.85
Depletion of adenine nucleotide translocator protein in heart mitochondria from doxorubicin-treated rats--relevance for mitochondrial dysfunction. Toxicology (2006) 0.84
Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors. Toxicol Appl Pharmacol (2007) 0.84
Perfluorooctane sulfonate-induced changes in fetal rat liver gene expression. Toxicology (2008) 0.83
Impact of diabetes on induction of the mitochondrial permeability transition. Rev Port Cardiol (2002) 0.83
Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function. Rev Port Cardiol (2004) 0.82
Direct, DNA pol-gamma-independent effects of nucleoside reverse transcriptase inhibitors on mitochondrial bioenergetics. Cardiovasc Toxicol (2004) 0.82
Reduction in cardiac mitochondrial calcium loading capacity is observable during alpha-naphthylisothiocyanate-induced acute cholestasis: a clue for hepatic-derived cardiomyopathies? Biochim Biophys Acta (2003) 0.81
Mitochondrial permeability transition as the critical target of N-acetyl perfluorooctane sulfonamide toxicity in vitro. Toxicol Sci (2004) 0.81
Dose response considerations in risk assessment--an overview of recent ILSI activities. Toxicol Lett (2008) 0.81
The safety of genetically modified foods produced through biotechnology. Toxicol Sci (2003) 0.80
Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol. Mitochondrion (2003) 0.80
Bile acids are toxic for isolated cardiac mitochondria: a possible cause for hepatic-derived cardiomyopathies? Cardiovasc Toxicol (2005) 0.80
Exposure to dibenzofuran affects lung mitochondrial function in vitro. Toxicol Mech Methods (2011) 0.78
Exposure to dibenzofuran triggers autophagy in lung cells. Toxicol Lett (2011) 0.78
Regulation of mitochondrial biogenesis in metabolic syndrome. Curr Drug Targets (2011) 0.78
Disruption of mitochondrial calcium homeostasis after chronic alpha-naphthylisothiocyanate administration: relevance for cholestasis. J Investig Med (2002) 0.77
Esterification prevents induction of the mitochondrial permeability transition by N-acetyl perfluorooctane sulfonamides. Chem Res Toxicol (2006) 0.77
Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease? Rev Port Cardiol (2003) 0.77
Toxicological evaluation of ammonium perfluorobutyrate in rats: twenty-eight-day and ninety-day oral gavage studies. Reprod Toxicol (2011) 0.77
Carvedilol: relation between antioxidant activity and inhibition of the mitochondrial permeability transition. Rev Port Cardiol (2003) 0.76
Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats. Mitochondrion (2004) 0.76
Mitochondrial Bioenergetics, Diabetes, and Aging: Top-Down Analysis Using the Diabetic Goto-Kakizaki (GK) Rat as a Model. Toxicol Mech Methods (2006) 0.76
Carvedilol inhibits the mitochondrial permeability transition by an antioxidant mechanism. Cardiovasc Toxicol (2004) 0.75
Scientific significance on the basis of the quality of mitochondrial preparations with which the experiments were performed. Toxicol Appl Pharmacol (2002) 0.75
Decreased ANT content in Zucker fatty rats: relevance for altered hepatic mitochondrial bioenergetics in steatosis. FEBS Lett (2006) 0.75
High-fat and obesogenic diets: current and future strategies to fight obesity and diabetes. Genes Nutr (2014) 0.75
Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of alpha-naphthylisothiocyanate. Toxicol Appl Pharmacol (2002) 0.75
Mitochondrial function is not affected by renal morphological changes in diabetic goto-kakizaki rat. Toxicol Mech Methods (2005) 0.75
Inorganic arsenic-induced intramitochondrial granules in mouse urothelium. Toxicol Pathol (2008) 0.75
Inhibition of the adenine nucleotide translocator by N-acetyl perfluorooctane sulfonamides in vitro. Toxicol Appl Pharmacol (2007) 0.75
Multitrack system for superfusing isolated cardiac myocytes. Am J Physiol Heart Circ Physiol (2003) 0.75
Determination of oxidative phosphorylation complexes activities. Methods Mol Biol (2015) 0.75
Nerolidol effects on mitochondrial and cellular energetics. Toxicol In Vitro (2011) 0.75
Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats. J Investig Med (2003) 0.75
Mechanisms of pyrethroid neurotoxicity: implications for cumulative risk assessment. Toxicology (2002) 0.75
Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion? Rev Port Cardiol (2002) 0.75
[Birthday wishes to Prof. Dr. med. Hans Marquardt]. Toxicology (2003) 0.75