David H Broide

Author PubWeight™ 75.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inhibition of airway remodeling in IL-5-deficient mice. J Clin Invest 2004 3.06
2 Esophageal remodeling in pediatric eosinophilic esophagitis. J Allergy Clin Immunol 2007 2.95
3 Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. Cancer Cell 2010 2.89
4 Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma. J Immunol 2004 2.67
5 Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils. Blood 2007 2.20
6 The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling. Nat Med 2011 2.12
7 Inhibition of experimental asthma by indoleamine 2,3-dioxygenase. J Clin Invest 2004 1.98
8 Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF-β1, and increase esophageal smooth muscle contraction. J Allergy Clin Immunol 2010 1.97
9 Resolution of airway inflammation following ovalbumin inhalation: comparison of ISS DNA and corticosteroids. Am J Respir Cell Mol Biol 2003 1.80
10 Molecular determinants of T cell epitope recognition to the common Timothy grass allergen. J Immunol 2010 1.76
11 Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production. J Allergy Clin Immunol 2013 1.73
12 Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance. J Exp Med 2013 1.67
13 Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease. J Immunol 2009 1.67
14 Accumulation of peribronchial mast cells in a mouse model of ovalbumin allergen induced chronic airway inflammation: modulation by immunostimulatory DNA sequences. J Immunol 2003 1.52
15 Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice. Am J Physiol Lung Cell Mol Physiol 2006 1.46
16 MMPs-2 and -14 Are Elevated in Eosinophilic Esophagitis and Reduced Following Topical Corticosteroid Therapy. J Pediatr Gastroenterol Nutr 2015 1.43
17 Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling. J Immunol 2009 1.43
18 ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6. Proc Natl Acad Sci U S A 2012 1.42
19 Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice. J Immunol 2007 1.41
20 STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria. Am J Physiol Lung Cell Mol Physiol 2012 1.37
21 Anti-Siglec-F antibody inhibits oral egg allergen induced intestinal eosinophilic inflammation in a mouse model. Clin Immunol 2009 1.31
22 Alternaria induces STAT6-dependent acute airway eosinophilia and epithelial FIZZ1 expression that promotes airway fibrosis and epithelial thickness. J Immunol 2012 1.30
23 Immunostimulatory DNA inhibits transforming growth factor-beta expression and airway remodeling. Am J Respir Cell Mol Biol 2003 1.28
24 Analysis of T cell responses to the major allergens from German cockroach: epitope specificity and relationship to IgE production. J Immunol 2012 1.24
25 Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13. Respir Res 2010 1.24
26 Innate immunity. J Allergy Clin Immunol 2009 1.23
27 3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis. Proc Natl Acad Sci U S A 2007 1.20
28 Adiponectin-deficient mice are protected against tobacco-induced inflammation and increased emphysema. Am J Physiol Lung Cell Mol Physiol 2010 1.18
29 Siglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis. J Pediatr Gastroenterol Nutr 2011 1.15
30 PI3K gamma-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling. Am J Physiol Lung Cell Mol Physiol 2008 1.12
31 Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals. Proc Natl Acad Sci U S A 2013 1.09
32 Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma. J Immunol 2012 1.08
33 Anti-IL-5 therapy reduces mast cell and IL-9 cell numbers in pediatric patients with eosinophilic esophagitis. J Allergy Clin Immunol 2013 1.08
34 Myeloid differentiation primary response gene 88 is required for the resolution of otitis media. J Infect Dis 2008 1.08
35 CD4+ cells are required for chronic eosinophilic lung inflammation but not airway remodeling. Am J Physiol Lung Cell Mol Physiol 2008 1.07
36 Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P. Hum Genet 2002 1.07
37 Down-regulation of caveolin-1, an inhibitor of transforming growth factor-beta signaling, in acute allergen-induced airway remodeling. J Biol Chem 2007 1.06
38 Airway fibrosis and angiogenesis due to eosinophil trafficking in chronic asthma. Curr Mol Med 2008 1.05
39 ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma. J Immunol 2014 1.04
40 Immunostimulatory DNA inhibits allergen-induced peribronchial angiogenesis in mice. J Allergy Clin Immunol 2006 1.00
41 Corticosteroids prevent myofibroblast accumulation and airway remodeling in mice. Am J Physiol Lung Cell Mol Physiol 2006 0.99
42 Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema. J Allergy Clin Immunol 2007 0.95
43 Immunostimulatory DNA reverses established allergen-induced airway remodeling. J Immunol 2004 0.94
44 Histamine-releasing factor has a proinflammatory role in mouse models of asthma and allergy. J Clin Invest 2011 0.93
45 A murine model to study leukocyte rolling and intravascular trafficking in lung microvessels. Am J Pathol 2003 0.91
46 Chronic OVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling. Int Immunopharmacol 2011 0.90
47 Chronic allergen challenge induces bronchial mast cell accumulation in BALB/c but not C57BL/6 mice and is independent of IL-9. Immunogenetics 2010 0.88
48 Coexposure to environmental tobacco smoke increases levels of allergen-induced airway remodeling in mice. J Immunol 2007 0.87
49 Indoleamine-2,3-dioxygenase modulation of allergic immune responses. Curr Allergy Asthma Rep 2006 0.86
50 Allergen-induced coexpression of bFGF and TGF-β1 by macrophages in a mouse model of airway remodeling: bFGF induces macrophage TGF-β1 expression in vitro. Int Arch Allergy Immunol 2010 0.83
51 Constitutive overexpression of IL-5 induces extramedullary hematopoiesis in the spleen. Blood 2002 0.83
52 Remodeling associated expression of matrix metalloproteinase 9 but not tissue inhibitor of metalloproteinase 1 in airway epithelium: modulation by immunostimulatory DNA. J Allergy Clin Immunol 2006 0.83
53 Hypoxia potentiates allergen induction of HIF-1α, chemokines, airway inflammation, TGF-β1, and airway remodeling in a mouse model. Clin Immunol 2013 0.82
54 Combination of corticosteroid therapy and allergen avoidance reverses allergen-induced airway remodeling in mice. J Allergy Clin Immunol 2005 0.82
55 Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function. J Mol Med (Berl) 2012 0.81
56 Environmental tobacco smoke exposure does not prevent corticosteroids reducing inflammation, remodeling, and airway hyperreactivity in mice exposed to allergen. Am J Physiol Lung Cell Mol Physiol 2009 0.81
57 Toll-like receptor-9 agonist inhibits airway inflammation, remodeling and hyperreactivity in mice exposed to chronic environmental tobacco smoke and allergen. Int Arch Allergy Immunol 2009 0.80
58 Inactivation of I kappaB-kinase-beta dependent genes in airway epithelium reduces tobacco smoke induced acute airway inflammation. Int Immunopharmacol 2010 0.76
59 Plasmid DNA encoding the respiratory syncytial virus G protein protects against RSV-induced airway hyperresponsiveness. Vaccine 2002 0.75