Published in J Am Chem Soc on March 03, 2004
Crystallization of bacteriorhodopsin from bicelle formulations at room temperature. Protein Sci (2005) 1.52
Carbon-oxygen hydrogen bonding in biological structure and function. J Biol Chem (2012) 1.35
Membrane protein folding: how important are hydrogen bonds? Curr Opin Struct Biol (2010) 1.19
Interaction and conformational dynamics of membrane-spanning protein helices. Protein Sci (2009) 1.19
Hydrogen-bonding and packing features of membrane proteins: functional implications. Biophys J (2007) 1.13
An unfolding story of helical transmembrane proteins. Biochemistry (2006) 1.10
Glycines: role in α-helical membrane protein structures and a potential indicator of native conformation. Biochemistry (2012) 1.01
A frequent, GxxxG-mediated, transmembrane association motif is optimized for the formation of interhelical Cα-H hydrogen bonds. Proc Natl Acad Sci U S A (2014) 0.98
Helical hairpin structure of influenza hemagglutinin fusion peptide stabilized by charge-dipole interactions between the N-terminal amino group and the second helix. J Am Chem Soc (2011) 0.94
Quantification of helix-helix binding affinities in micelles and lipid bilayers. Protein Sci (2004) 0.93
Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state. Biochim Biophys Acta (2011) 0.92
Computational studies of membrane proteins: models and predictions for biological understanding. Biochim Biophys Acta (2011) 0.88
Transmembrane helix-helix association: relative stabilities at low pH. Biochemistry (2006) 0.81
A Gly-zipper motif mediates homodimerization of the transmembrane domain of the mitochondrial kinase ADCK3. J Am Chem Soc (2014) 0.79
Marginally hydrophobic transmembrane α-helices shaping membrane protein folding. Protein Sci (2015) 0.75
Computational Approaches for Revealing the Structure of Membrane Transporters: Case Study on Bilitranslocase. Comput Struct Biotechnol J (2017) 0.75
The Database of Interacting Proteins: 2004 update. Nucleic Acids Res (2004) 23.67
Bicelle crystallization: a new method for crystallizing membrane proteins yields a monomeric bacteriorhodopsin structure. J Mol Biol (2002) 3.11
An architectural framework that may lie at the core of the postsynaptic density. Science (2006) 2.91
The many faces of SAM. Sci STKE (2005) 2.87
The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating. Proc Natl Acad Sci U S A (2008) 2.82
Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel. Nat Struct Mol Biol (2005) 2.38
Enhanced antibody half-life improves in vivo activity. Nat Biotechnol (2010) 2.33
The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors. Proc Natl Acad Sci U S A (2004) 2.19
Side-chain contributions to membrane protein structure and stability. J Mol Biol (2004) 2.13
Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins. Nature (2008) 2.03
SAM domains: uniform structure, diversity of function. Trends Biochem Sci (2003) 1.94
Transmembrane glycine zippers: physiological and pathological roles in membrane proteins. Proc Natl Acad Sci U S A (2005) 1.90
Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state. J Biol Chem (2004) 1.84
The SAM domain of polyhomeotic forms a helical polymer. Nat Struct Biol (2002) 1.73
A novel cytoplasmic tail MXXXL motif mediates the internalization of prostate-specific membrane antigen. Mol Biol Cell (2003) 1.60
Derepression by depolymerization; structural insights into the regulation of Yan by Mae. Cell (2004) 1.59
Probing membrane protein unfolding with pulse proteolysis. J Mol Biol (2010) 1.58
The molecular basis of the Caskin1 and Mint1 interaction with CASK. J Mol Biol (2011) 1.56
Crystallization of bacteriorhodopsin from bicelle formulations at room temperature. Protein Sci (2005) 1.52
A limited universe of membrane protein families and folds. Protein Sci (2006) 1.41
HotPatch: a statistical approach to finding biologically relevant features on protein surfaces. J Mol Biol (2007) 1.32
Methods for measuring the thermodynamic stability of membrane proteins. Methods Enzymol (2009) 1.29
Snorkeling preferences foster an amino acid composition bias in transmembrane helices. J Mol Biol (2004) 1.29
Regulation of enzyme localization by polymerization: polymer formation by the SAM domain of diacylglycerol kinase delta1. Structure (2008) 1.28
Post-translational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation. Mol Cell Proteomics (2010) 1.28
Proline substitutions are not easily accommodated in a membrane protein. J Mol Biol (2004) 1.27
Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer. J Biol Chem (2005) 1.26
A simple method for modeling transmembrane helix oligomers. J Mol Biol (2003) 1.19
Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants. BMC Neurosci (2008) 1.17
Dramatic destabilization of transmembrane helix interactions by features of natural membrane environments. J Am Chem Soc (2011) 1.17
The affinity of GXXXG motifs in transmembrane helix-helix interactions is modulated by long-range communication. J Biol Chem (2004) 1.16
Shifting hydrogen bonds may produce flexible transmembrane helices. Proc Natl Acad Sci U S A (2012) 1.16
Method to measure strong protein-protein interactions in lipid bilayers using a steric trap. Proc Natl Acad Sci U S A (2010) 1.15
Flip-flopping membrane proteins. Nat Struct Mol Biol (2006) 1.13
A role for zinc in postsynaptic density asSAMbly and plasticity? Trends Biochem Sci (2006) 1.10
Genetic selection system for improving recombinant membrane protein expression in E. coli. Protein Sci (2009) 1.10
Structural imperatives impose diverse evolutionary constraints on helical membrane proteins. Proc Natl Acad Sci U S A (2009) 1.08
Crystallizing membrane proteins using lipidic bicelles. Methods (2011) 1.08
Membrane channel structure of Helicobacter pylori vacuolating toxin: role of multiple GXXXG motifs in cylindrical channels. Proc Natl Acad Sci U S A (2004) 1.06
Similar energetic contributions of packing in the core of membrane and water-soluble proteins. J Am Chem Soc (2009) 1.06
A human sterile alpha motif domain polymerizome. Protein Sci (2011) 1.06
Identifying polymer-forming SAM domains. Proteins (2009) 1.06
Regulation of clathrin adaptor function in endocytosis: novel role for the SAM domain. EMBO J (2010) 1.06
Janus model of the Na,K-ATPase beta-subunit transmembrane domain: distinct faces mediate alpha/beta assembly and beta-beta homo-oligomerization. J Mol Biol (2006) 1.05
Construction of helix-bundle membrane proteins. Adv Protein Chem (2003) 1.05
Native interface of the SAM domain polymer of TEL. BMC Struct Biol (2002) 1.03
Point mutations in membrane proteins reshape energy landscape and populate different unfolding pathways. J Mol Biol (2007) 1.02
Analysis of side-chain rotamers in transmembrane proteins. Biophys J (2004) 1.00
Polymer-driven crystallization. Protein Sci (2007) 1.00
TMKink: a method to predict transmembrane helix kinks. Protein Sci (2011) 0.98
Dieselzymes: development of a stable and methanol tolerant lipase for biodiesel production by directed evolution. Biotechnol Biofuels (2013) 0.98
Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response. Genes Dev (2005) 0.96
Protein unfolding with a steric trap. J Am Chem Soc (2009) 0.96
Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK. Structure (2011) 0.94
G-protein-coupled receptor structures were not built in a day. Protein Sci (2009) 0.94
Mae inhibits Pointed-P2 transcriptional activity by blocking its MAPK docking site. EMBO J (2005) 0.93
SAM domains can utilize similar surfaces for the formation of polymers and closed oligomers. J Mol Biol (2004) 0.93
Oligomerization-dependent association of the SAM domains from Schizosaccharomyces pombe Byr2 and Ste4. J Biol Chem (2002) 0.92
Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state. Biochim Biophys Acta (2011) 0.92
Evidence of a novel mevalonate pathway in archaea. Biochemistry (2014) 0.92
A transmembrane segment mimic derived from Escherichia coli diacylglycerol kinase inhibits protein activity. J Biol Chem (2003) 0.92
Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffold. J Med Chem (2008) 0.91
A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates. Protein Sci (2014) 0.89
Revisiting the folding kinetics of bacteriorhodopsin. Protein Sci (2011) 0.89
A model of the closed form of the nicotinic acetylcholine receptor m2 channel pore. Biophys J (2004) 0.89
How to prepare membrane proteins for solid-state NMR: A case study on the alpha-helical integral membrane protein diacylglycerol kinase from E. coli. Chembiochem (2005) 0.89
Transmembrane domain of myelin protein zero can form dimers: possible implications for myelin construction. Biochemistry (2007) 0.88
Evaluation of C-H cdots, three dots, centered O hydrogen bonds in native and misfolded proteins. J Mol Biol (2002) 0.87
Zinc binding drives sheet formation by the SAM domain of diacylglycerol kinase δ. Biochemistry (2010) 0.87
Membrane proteins can have high kinetic stability. J Am Chem Soc (2013) 0.87
Network rewiring is an important mechanism of gene essentiality change. Sci Rep (2012) 0.86
Measuring membrane protein stability under native conditions. Proc Natl Acad Sci U S A (2013) 0.84
Structural differences between thermophilic and mesophilic membrane proteins. Protein Sci (2012) 0.83
Asymmetric amino acid compositions of transmembrane beta-strands. Protein Sci (2004) 0.82
Cell biology: border crossing. Nature (2005) 0.81
Bacteriorhodopsin folds through a poorly organized transition state. J Am Chem Soc (2014) 0.81
Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. Protein Sci (2014) 0.81
Crystal structure of the central coiled-coil domain from human liprin-β2. Biochemistry (2011) 0.81
Crystallization of membrane proteins in bicelles. Methods Mol Biol (2012) 0.79
Rampant exchange of the structure and function of extramembrane domains between membrane and water soluble proteins. PLoS Comput Biol (2013) 0.78
Measuring transmembrane helix interaction strengths in lipid bilayers using steric trapping. Methods Mol Biol (2013) 0.78
An energetic scale for equilibrium H/D fractionation factors illuminates hydrogen bond free energies in proteins. Protein Sci (2014) 0.77
Protein design by fusion: implications for protein structure prediction and evolution. Acta Crystallogr D Biol Crystallogr (2013) 0.77