| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
|
Nat Genet
|
2012
|
4.37
|
|
2
|
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
|
Nat Genet
|
2014
|
4.13
|
|
3
|
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.
|
PLoS Med
|
2011
|
3.94
|
|
4
|
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.
|
N Engl J Med
|
2016
|
3.88
|
|
5
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
6
|
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
|
PLoS Genet
|
2012
|
2.34
|
|
7
|
Natural competence in the hyperthermophilic archaeon Pyrococcus furiosus facilitates genetic manipulation: construction of markerless deletions of genes encoding the two cytoplasmic hydrogenases.
|
Appl Environ Microbiol
|
2011
|
1.81
|
|
8
|
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
|
Nat Genet
|
2013
|
1.72
|
|
9
|
Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors.
|
Eur J Epidemiol
|
2015
|
1.51
|
|
10
|
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry.
|
PLoS Genet
|
2013
|
1.51
|
|
11
|
Engineering a three-cysteine, one-histidine ligand environment into a new hyperthermophilic archaeal Rieske-type [2Fe-2S] ferredoxin from Sulfolobus solfataricus.
|
J Biol Chem
|
2004
|
1.32
|
|
12
|
Molecular insights into the metal selectivity of the copper(I)-sensing repressor CsoR from Bacillus subtilis.
|
Biochemistry
|
2009
|
1.29
|
|
13
|
Demographic characteristics of elite Kenyan endurance runners.
|
J Sports Sci
|
2006
|
1.28
|
|
14
|
The metalloregulatory zinc site in Streptococcus pneumoniae AdcR, a zinc-activated MarR family repressor.
|
J Mol Biol
|
2010
|
1.25
|
|
15
|
Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes.
|
Diabetes
|
2013
|
1.25
|
|
16
|
Biophysical characterization of the iron in mitochondria from Atm1p-depleted Saccharomyces cerevisiae.
|
Biochemistry
|
2009
|
1.23
|
|
17
|
Structural elements of metal selectivity in metal sensor proteins.
|
Proc Natl Acad Sci U S A
|
2003
|
1.20
|
|
18
|
Transcription factor B contacts promoter DNA near the transcription start site of the archaeal transcription initiation complex.
|
J Biol Chem
|
2003
|
1.17
|
|
19
|
Unnatural amino acid substitution as a probe of the allosteric coupling pathway in a mycobacterial Cu(I) sensor.
|
J Am Chem Soc
|
2009
|
1.14
|
|
20
|
Age at menarche and type 2 diabetes risk: the EPIC-InterAct study.
|
Diabetes Care
|
2013
|
1.13
|
|
21
|
Control of copper resistance and inorganic sulfur metabolism by paralogous regulators in Staphylococcus aureus.
|
J Biol Chem
|
2011
|
1.12
|
|
22
|
A cysteine-rich CCG domain contains a novel [4Fe-4S] cluster binding motif as deduced from studies with subunit B of heterodisulfide reductase from Methanothermobacter marburgensis.
|
Biochemistry
|
2007
|
1.12
|
|
23
|
Engineering metal ion coordination to regulate amyloid fibril assembly and toxicity.
|
Proc Natl Acad Sci U S A
|
2007
|
1.10
|
|
24
|
SurR: a transcriptional activator and repressor controlling hydrogen and elemental sulphur metabolism in Pyrococcus furiosus.
|
Mol Microbiol
|
2008
|
1.09
|
|
25
|
The ACTN3 R577X polymorphism in East and West African athletes.
|
Med Sci Sports Exerc
|
2007
|
1.08
|
|
26
|
Auranofin disrupts selenium metabolism in Clostridium difficile by forming a stable Au-Se adduct.
|
J Biol Inorg Chem
|
2009
|
1.06
|
|
27
|
Recombinogenic properties of Pyrococcus furiosus strain COM1 enable rapid selection of targeted mutants.
|
Appl Environ Microbiol
|
2012
|
1.05
|
|
28
|
Deletion strains reveal metabolic roles for key elemental sulfur-responsive proteins in Pyrococcus furiosus.
|
J Bacteriol
|
2011
|
1.03
|
|
29
|
Effects of single bout of very high-intensity exercise on metabolic health biomarkers in overweight/obese sedentary men.
|
Metabolism
|
2012
|
1.01
|
|
30
|
Kinetic and structural characterization of manganese(II)-loaded methionyl aminopeptidases.
|
Biochemistry
|
2002
|
1.00
|
|
31
|
Enteric coated HPMC capsules designed to achieve intestinal targeting.
|
Int J Pharm
|
2002
|
0.96
|
|
32
|
Mechanism of oxygen detoxification by the surprisingly oxygen-tolerant hyperthermophilic archaeon, Pyrococcus furiosus.
|
Proc Natl Acad Sci U S A
|
2012
|
0.96
|
|
33
|
A Cu(I)-sensing ArsR family metal sensor protein with a relaxed metal selectivity profile.
|
Biochemistry
|
2008
|
0.95
|
|
34
|
SurR regulates hydrogen production in Pyrococcus furiosus by a sulfur-dependent redox switch.
|
Mol Microbiol
|
2010
|
0.94
|
|
35
|
Structural studies of the interaction of S-adenosylmethionine with the [4Fe-4S] clusters in biotin synthase and pyruvate formate-lyase activating enzyme.
|
Protein Sci
|
2003
|
0.94
|
|
36
|
Br-rich tips of calcified crab claws are less hard but more fracture resistant: a comparison of mineralized and heavy-element biological materials.
|
J Struct Biol
|
2009
|
0.93
|
|
37
|
Mutational Analyses of the Enzymes Involved in the Metabolism of Hydrogen by the Hyperthermophilic Archaeon Pyrococcus furiosus.
|
Front Microbiol
|
2012
|
0.93
|
|
38
|
Modulating amyloid self-assembly and fibril morphology with Zn(II).
|
J Am Chem Soc
|
2006
|
0.93
|
|
39
|
The dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase from Haemophilus influenzae is a dinuclear metallohydrolase.
|
J Am Chem Soc
|
2003
|
0.91
|
|
40
|
Impact of peroxisome proliferator-activated receptors gamma and delta on adiposity in toddlers and preschoolers in the GENESIS Study.
|
Obesity (Silver Spring)
|
2008
|
0.90
|
|
41
|
Redox-dependent structural changes in archaeal and bacterial Rieske-type [2Fe-2S] clusters.
|
Protein Sci
|
2002
|
0.89
|
|
42
|
No association between ACE gene variation and endurance athlete status in Ethiopians.
|
Med Sci Sports Exerc
|
2011
|
0.87
|
|
43
|
Rational design of a mononuclear metal site into the archaeal Rieske-type protein scaffold.
|
J Biol Chem
|
2005
|
0.86
|
|
44
|
Structural basis for metal binding specificity: the N-terminal cadmium binding domain of the P1-type ATPase CadA.
|
J Mol Biol
|
2005
|
0.85
|
|
45
|
Molecular structure and biochemical properties of the HCCH-Zn2+ site in HIV-1 Vif.
|
Biochemistry
|
2009
|
0.85
|
|
46
|
Spectroscopic determination of the thermodynamics of cobalt and zinc binding to GATA proteins.
|
Biochemistry
|
2004
|
0.84
|
|
47
|
Thermal stability of the [Fe(SCys)(4)] site in Clostridium pasteurianum rubredoxin: contributions of the local environment and Cys ligand protonation.
|
J Biol Inorg Chem
|
2001
|
0.84
|
|
48
|
Novel [2Fe-2S]-type redox center C in SdhC of archaeal respiratory complex II from Sulfolobus tokodaii strain 7.
|
J Biol Chem
|
2002
|
0.84
|
|
49
|
In vitro and in vivo pharmacoscintigraphic evaluation of ibuprofen hypromellose and gelatin capsules.
|
Pharm Res
|
2004
|
0.83
|
|
50
|
Dipeptide-based models of nickel superoxide dismutase: solvent effects highlight a critical role to Ni-S bonding and active site stabilization.
|
Inorg Chem
|
2011
|
0.83
|
|
51
|
Mitochondrial haplogroups associated with elite Japanese athlete status.
|
Br J Sports Med
|
2010
|
0.83
|
|
52
|
Multiple metal binding domains enhance the Zn(II) selectivity of the divalent metal ion transporter AztA.
|
Biochemistry
|
2007
|
0.81
|
|
53
|
An age-dependent diet-modified effect of the PPARγ Pro12Ala polymorphism in children.
|
Metabolism
|
2010
|
0.80
|
|
54
|
The CCG-domain-containing subunit SdhE of succinate:quinone oxidoreductase from Sulfolobus solfataricus P2 binds a [4Fe-4S] cluster.
|
J Biol Inorg Chem
|
2008
|
0.80
|
|
55
|
Direct interaction of coenzyme M with the active-site Fe-S cluster of heterodisulfide reductase.
|
FEBS Lett
|
2005
|
0.80
|
|
56
|
Coordination and geometry of the nickel atom in active methyl-coenzyme M reductase from Methanothermobacter marburgensis as detected by X-ray absorption spectroscopy.
|
J Biol Inorg Chem
|
2002
|
0.80
|
|
57
|
A stable mercury-containing complex of the organomercurial lyase MerB: catalysis, product release, and direct transfer to MerA.
|
Biochemistry
|
2004
|
0.80
|
|
58
|
X-ray absorption spectroscopic analysis of reductive [2Fe-2S] cluster degradation in hyperthermophilic archaeal succinate:caldariellaquinone oxidoreductase subunits.
|
Biochemistry
|
2003
|
0.79
|
|
59
|
The long and short of telomere length and diabetes.
|
Diabetes
|
2014
|
0.79
|
|
60
|
Regulation of iron metabolism by Pyrococcus furiosus.
|
J Bacteriol
|
2013
|
0.78
|
|
61
|
Structural characterization of Zn(II)-, Co(II)-, and Mn(II)-loaded forms of the argE-encoded N-acetyl-L-ornithine deacetylase from Escherichia coli.
|
J Inorg Biochem
|
2012
|
0.77
|
|
62
|
Does a short breastfeeding period protect from FTO-induced adiposity in children?
|
Int J Pediatr Obes
|
2010
|
0.76
|
|
63
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
|
64
|
Engineered single-chain, antiparallel, coiled coil mimics the MerR metal binding site.
|
J Bacteriol
|
2004
|
0.75
|
|
65
|
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
PLoS Genet
|
2017
|
0.75
|
|
66
|
Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
|
Nat Commun
|
2015
|
0.75
|
|
67
|
Genetic markers of insulin sensitivity and insulin secretion are associated with spontaneous postnatal growth and response to growth hormone treatment in short SGA children: the North European SGA Study (NESGAS).
|
J Clin Endocrinol Metab
|
2014
|
0.75
|
|
68
|
Y chromosome haplogroups of elite Ethiopian endurance runners.
|
Hum Genet
|
2004
|
0.75
|
|
69
|
Corrigendum: Rare coding variants and X-linked loci associated with age at menarche.
|
Nat Commun
|
2015
|
0.75
|
|
70
|
Corrigendum: Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.
|
Nat Genet
|
2017
|
0.75
|