Selection in vitro of allosteric ribozymes.

A high-throughput screen for synthetic riboswitches reveals mechanistic insights into their function. Chem Biol (2007) 1.56

Engineering ligand-responsive gene-control elements: lessons learned from natural riboswitches. Gene Ther (2009) 1.11

The importance of peripheral sequences in determining the metal selectivity of an in vitro-selected Co(2+) -dependent DNAzyme. Chembiochem (2012) 0.77

In vitro selection of glmS ribozymes. Methods Mol Biol (2009) 0.75

Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression. Nature (2002) 8.14

Gene regulation by riboswitches. Nat Rev Mol Cell Biol (2004) 7.00

Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria. Cell (2003) 6.21

Control of gene expression by a natural metabolite-responsive ribozyme. Nature (2004) 6.04

Regulation of bacterial gene expression by riboswitches. Annu Rev Microbiol (2005) 5.66

Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs. Chem Biol (2004) 5.44

An mRNA structure that controls gene expression by binding FMN. Proc Natl Acad Sci U S A (2002) 5.02

A glycine-dependent riboswitch that uses cooperative binding to control gene expression. Science (2004) 4.91

Genetic control by a metabolite binding mRNA. Chem Biol (2002) 4.85

New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control. Proc Natl Acad Sci U S A (2004) 4.35

The structural and functional diversity of metabolite-binding riboswitches. Annu Rev Biochem (2009) 4.20

Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature (2006) 3.90

Control of alternative RNA splicing and gene expression by eukaryotic riboswitches. Nature (2007) 3.87

Adenine riboswitches and gene activation by disruption of a transcription terminator. Nat Struct Mol Biol (2003) 3.84

Riboswitches as versatile gene control elements. Curr Opin Struct Biol (2005) 3.83

The distributions, mechanisms, and structures of metabolite-binding riboswitches. Genome Biol (2007) 3.80

An mRNA structure that controls gene expression by binding S-adenosylmethionine. Nat Struct Biol (2003) 3.75

The speed of RNA transcription and metabolite binding kinetics operate an FMN riboswitch. Mol Cell (2005) 3.62

Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline. Nucleic Acids Res (2007) 3.59

Metabolite-binding RNA domains are present in the genes of eukaryotes. RNA (2003) 3.42

An mRNA structure in bacteria that controls gene expression by binding lysine. Genes Dev (2003) 3.37

Structural basis of ligand binding by a c-di-GMP riboswitch. Nat Struct Mol Biol (2009) 3.28

Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes. Genome Biol (2010) 3.19

Riboswitches as antibacterial drug targets. Nat Biotechnol (2006) 3.01

The kinetics of ligand binding by an adenine-sensing riboswitch. Biochemistry (2005) 2.98

Antibacterial lysine analogs that target lysine riboswitches. Nat Chem Biol (2006) 2.94

In-line probing analysis of riboswitches. Methods Mol Biol (2008) 2.76

Tandem riboswitch architectures exhibit complex gene control functions. Science (2006) 2.63

A riboswitch selective for the queuosine precursor preQ1 contains an unusually small aptamer domain. Nat Struct Mol Biol (2007) 2.52

Coenzyme B12 riboswitches are widespread genetic control elements in prokaryotes. Nucleic Acids Res (2004) 2.47

Genetic control by metabolite-binding riboswitches. Chembiochem (2003) 2.32

Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria. Genome Biol (2005) 2.32

6S RNA is a widespread regulator of eubacterial RNA polymerase that resembles an open promoter. RNA (2005) 2.28

Computational design and experimental validation of oligonucleotide-sensing allosteric ribozymes. Nat Biotechnol (2005) 2.22

Riboswitch control of gene expression in plants by splicing and alternative 3' end processing of mRNAs. Plant Cell (2007) 2.18

Thiamine pyrophosphate riboswitches are targets for the antimicrobial compound pyrithiamine. Chem Biol (2005) 2.00

Ligand binding and gene control characteristics of tandem riboswitches in Bacillus anthracis. RNA (2007) 1.96

Characteristics of the glmS ribozyme suggest only structural roles for divalent metal ions. RNA (2006) 1.81

Ribozyme speed limits. RNA (2003) 1.68

Confirmation of a second natural preQ1 aptamer class in Streptococcaceae bacteria. RNA (2008) 1.67

Unique glycine-activated riboswitch linked to glycine-serine auxotrophy in SAR11. Environ Microbiol (2009) 1.61

R2R--software to speed the depiction of aesthetic consensus RNA secondary structures. BMC Bioinformatics (2011) 1.60

Guanine riboswitch variants from Mesoplasma florum selectively recognize 2'-deoxyguanosine. Proc Natl Acad Sci U S A (2007) 1.54

Roseoflavin is a natural antibacterial compound that binds to FMN riboswitches and regulates gene expression. RNA Biol (2009) 1.50

Riboswitches in eubacteria sense the second messenger c-di-AMP. Nat Chem Biol (2013) 1.47

Exceptional structured noncoding RNAs revealed by bacterial metagenome analysis. Nature (2009) 1.43

The aptamer core of SAM-IV riboswitches mimics the ligand-binding site of SAM-I riboswitches. RNA (2008) 1.39

Riboswitches that sense S-adenosylhomocysteine and activate genes involved in coenzyme recycling. Mol Cell (2008) 1.38

Characteristics of ligand recognition by a glmS self-cleaving ribozyme. Angew Chem Int Ed Engl (2006) 1.38

Riboswitches that sense S-adenosylmethionine and S-adenosylhomocysteine. Biochem Cell Biol (2008) 1.35

A widespread riboswitch candidate that controls bacterial genes involved in molybdenum cofactor and tungsten cofactor metabolism. Mol Microbiol (2008) 1.33

A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria. RNA (2009) 1.32

Design and antimicrobial action of purine analogues that bind Guanine riboswitches. ACS Chem Biol (2009) 1.29

Identification of hammerhead ribozymes in all domains of life reveals novel structural variations. PLoS Comput Biol (2011) 1.29

Purine sensing by riboswitches. Biol Cell (2008) 1.24

Eukaryotic resistance to fluoride toxicity mediated by a widespread family of fluoride export proteins. Proc Natl Acad Sci U S A (2013) 1.22

Identification of candidate structured RNAs in the marine organism 'Candidatus Pelagibacter ubique'. BMC Genomics (2009) 1.21

Riboswitches: from ancient gene-control systems to modern drug targets. Future Microbiol (2009) 1.16

Finding non-coding RNAs through genome-scale clustering. J Bioinform Comput Biol (2009) 1.16

Challenges of ligand identification for riboswitch candidates. RNA Biol (2011) 1.16

A eubacterial riboswitch class that senses the coenzyme tetrahydrofolate. Chem Biol (2010) 1.14

Integron attI1 sites, not riboswitches, associate with antibiotic resistance genes. Cell (2013) 1.10

Identification of a large noncoding RNA in extremophilic eubacteria. Proc Natl Acad Sci U S A (2006) 1.08

Molecular-recognition characteristics of SAM-binding riboswitches. Angew Chem Int Ed Engl (2006) 1.06

Evidence for widespread gene control function by the ydaO riboswitch candidate. J Bacteriol (2010) 1.05

Ligating DNA with DNA. J Am Chem Soc (2004) 1.01

Engineered allosteric ribozymes that respond to specific divalent metal ions. Nucleic Acids Res (2005) 1.01

An expanded collection and refined consensus model of glmS ribozymes. RNA (2011) 1.00

Eukaryotic TPP riboswitch regulation of alternative splicing involving long-distance base pairing. Nucleic Acids Res (2013) 0.97

Bacterial aptamers that selectively bind glutamine. RNA Biol (2011) 0.95

Substrate specificity and reaction kinetics of an X-motif ribozyme. RNA (2003) 0.94

Association of OLE RNA with bacterial membranes via an RNA-protein interaction. Mol Microbiol (2010) 0.94

Mechanism for gene control by a natural allosteric group I ribozyme. RNA (2011) 0.93

Examination of the structural and functional versatility of glmS ribozymes by using in vitro selection. Nucleic Acids Res (2006) 0.92

Engineering high-speed allosteric hammerhead ribozymes. Biol Chem (2007) 0.92

Fluoride enhances the activity of fungicides that destabilize cell membranes. Bioorg Med Chem Lett (2012) 0.91

A plant 5S ribosomal RNA mimic regulates alternative splicing of transcription factor IIIA pre-mRNAs. Nat Struct Mol Biol (2009) 0.89

Small, highly active DNAs that hydrolyze DNA. J Am Chem Soc (2013) 0.89

Engineered allosteric ribozymes that sense the bacterial second messenger cyclic diguanosyl 5'-monophosphate. Anal Chem (2012) 0.88

In vitro selection and characterization of cellulose-binding DNA aptamers. Nucleic Acids Res (2007) 0.86

The power of riboswitches. Sci Am (2007) 0.80

Production of single-stranded DNAs by self-cleavage of rolling-circle amplification products. Biotechniques (2013) 0.80

Identification of ligand analogues that control c-di-GMP riboswitches. ACS Chem Biol (2012) 0.78

Ancient, giant riboswitches at atomic resolution. Nat Struct Mol Biol (2012) 0.77

Mechanism and distribution of glmS ribozymes. Methods Mol Biol (2012) 0.77

OLE RNA protects extremophilic bacteria from alcohol toxicity. Nucleic Acids Res (2012) 0.75

In vitro selection of glmS ribozymes. Methods Mol Biol (2009) 0.75

In vitro selection of allosteric ribozymes that sense the bacterial second messenger c-di-GMP. Methods Mol Biol (2014) 0.75