Published in Arthritis Res Ther on February 19, 2004
Estrogen alone and joint symptoms in the Women's Health Initiative randomized trial. Menopause (2013) 1.42
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The effects of bone turnover rate on subchondral trabecular bone structure and cartilage damage in the osteoarthritis rat model. Rheumatol Int (2009) 0.85
Evidence of changes to skeletal muscle contractile properties during the initiation of disease in the ageing guinea pig model of osteoarthritis. Longev Healthspan (2013) 0.84
Tibolone inhibits bone resorption without secondary positive effects on cartilage degradation. BMC Musculoskelet Disord (2008) 0.84
Localization of estrogen receptors alpha and beta in the articular surface of the rat femur. Acta Histochem Cytochem (2007) 0.83
Effects of calcitonin on knee osteoarthritis and quality of life. Rheumatol Int (2012) 0.83
Effects of dietary isoflavones from Puerariae radix on lipid and bone metabolism in ovariectomized rats. Nutrients (2013) 0.82
Pulse electromagnetic fields effects on serum E2 levels, chondrocyte apoptosis, and matrix metalloproteinase-13 expression in ovariectomized rats. Rheumatol Int (2008) 0.82
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The influence of long-term treadmill exercise on bone mass and articular cartilage in ovariectomized rats. BMC Musculoskelet Disord (2010) 0.81
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Effects of pulsed electromagnetic fields on the mRNA expression of CAII and RANK in ovariectomized rats. Rheumatol Int (2011) 0.77
Anti-osteoporotic effects of Angelica sinensis (Oliv.) Diels extract on ovariectomized rats and its oral toxicity in rats. Nutrients (2014) 0.77
Calcitonin attenuates cartilage degeneration and nociception in an experimental rat model of osteoarthritis: role of TGF-β in chondrocytes. Sci Rep (2016) 0.76
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Adult mice lacking the type 2 iodothyronine deiodinase have increased subchondral bone but normal articular cartilage. Thyroid (2015) 0.76
Effect of age-related cartilage turnover on serum C-telopeptide of collagen type II and osteocalcin levels in growing rabbits with and without surgically induced osteoarthritis. Biomed Res Int (2014) 0.76
Early Detection of Tibial Cartilage Degradation and Cancellous Bone Loss in an Ovariectomized Rat Model. Biomed Res Int (2017) 0.75
Glucosamine and chondroitin sulfate association increases tibial epiphyseal growth plate proliferation and bone formation in ovariectomized rats. Clinics (Sao Paulo) (2014) 0.75
The biological effects of sex hormones on rabbit articular chondrocytes from different genders. Biomed Res Int (2014) 0.75
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The Evaluation of the Effect of Herbal Extract on Osteoarthritis: In Vitro and In Vivo Study. Prev Nutr Food Sci (2016) 0.75
A microarray analysis of full depth knee cartilage of ovariectomized rats. BMC Res Notes (2011) 0.75
Age dependent changes in cartilage matrix, subchondral bone mass, and estradiol levels in blood serum, in naturally occurring osteoarthritis in Guinea pigs. Int J Mol Sci (2014) 0.75
Effects of ultrasound on estradiol level, bone mineral density, bone biomechanics and matrix metalloproteinase-13 expression in ovariectomized rabbits. Exp Ther Med (2015) 0.75
L-Carnitine, but not coenzyme Q10, enhances the anti-osteoporotic effect of atorvastatin in ovariectomized rats. J Zhejiang Univ Sci B (2016) 0.75
Evaluation of the effect of oral administration of collagen peptides on an experimental rat osteoarthritis model. Exp Ther Med (2017) 0.75
Relationship between soy milk intake and radiographic knee joint space narrowing and osteophytes. Rheumatol Int (2016) 0.75
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Preventive effects of kudzu root on bone loss and cartilage degradation in ovariectomized rat. Am J Transl Res (2017) 0.75
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Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage. Ann Rheum Dis (2001) 2.18
The increasing impact of arthritis on public health. J Rheumatol Suppl (2000) 2.10
Collagen type II C-telopeptide fragments as an index of cartilage degradation. Bone (2001) 2.00
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Induction of osteoarthritis in the rat by surgical tear of the meniscus: Inhibition of joint damage by a matrix metalloproteinase inhibitor. Osteoarthritis Cartilage (2002) 1.67
Functional estrogen receptors in adult articular cartilage: estrogen replacement therapy increases chondrocyte synthesis of proteoglycans and insulin-like growth factor binding protein 2. Arthritis Rheum (2000) 1.63
Association of baseline levels of markers of bone and cartilage degradation with long-term progression of joint damage in patients with early rheumatoid arthritis: the COBRA study. Arthritis Rheum (2002) 1.55
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Cartilage turnover assessed with a newly developed assay measuring collagen type II degradation products: influence of age, sex, menopause, hormone replacement therapy, and body mass index. Ann Rheum Dis (2003) 1.40
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Transgenic mouse models for studying the role of cartilage macromolecules in osteoarthritis. Rheumatology (Oxford) (2002) 1.00
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Hormone replacement therapy and patterns of osteoarthritis: baseline data from the Ulm Osteoarthritis Study. Ann Rheum Dis (2000) 0.90
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Immunohistochemical analysis of several proteolytic enzymes as parameters of cartilage degradation. Pathol Res Pract (1998) 0.87
Idoxifene, a novel selective estrogen receptor modulator, is effective in a rat model of adjuvant-induced arthritis. J Pharmacol Exp Ther (1999) 0.84
Estrogens and receptors: an evolving concept. Climacteric (2002) 0.82
Development and application of a serum C-telopeptide and osteocalcin assay to measure bone turnover in an ovariectomized rat model. Calcif Tissue Int (2000) 0.79
Synthesis and pharmacological evaluation of novel cis-3,4-diaryl-hydroxychromanes as high affinity partial agonists for the estrogen receptor. Bioorg Med Chem (2002) 0.79
Efficacy of levormeloxifene in the prevention of postmenopausal bone loss and on the lipid profile compared to low dose hormone replacement therapy. J Clin Endocrinol Metab (2001) 0.78
Biomarkers predict radiographic progression in early rheumatoid arthritis and perform well compared with traditional markers. Arthritis Rheum (2007) 2.50
Early postmenopausal hormone therapy may prevent cognitive impairment later in life. Menopause (2005) 1.77
Suppression of elevated cartilage turnover in postmenopausal women and in ovariectomized rats by estrogen and a selective estrogen-receptor modulator (SERM). Menopause (2004) 1.66
Association of baseline levels of markers of bone and cartilage degradation with long-term progression of joint damage in patients with early rheumatoid arthritis: the COBRA study. Arthritis Rheum (2002) 1.55
P2X7 receptor-deficient mice are susceptible to bone cancer pain. Pain (2011) 1.53
Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities. Microsc Res Tech (2003) 1.34
A scrutiny of matrix metalloproteinases in osteoclasts: evidence for heterogeneity and for the presence of MMPs synthesized by other cells. Bone (2004) 1.29
Matrix metalloproteinase-dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosis. J Biol Chem (2002) 1.28
Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption. Am J Pathol (2005) 1.26
Transforming growth factor-beta controls human osteoclastogenesis through the p38 MAPK and regulation of RANK expression. J Biol Chem (2003) 1.21
Resveratrol inhibits myeloma cell growth, prevents osteoclast formation, and promotes osteoblast differentiation. Cancer Res (2005) 1.18
Alendronate has a residual effect on bone mass in postmenopausal Danish women up to 7 years after treatment withdrawal. Bone (2003) 1.16
Involvement of human endogenous retroviral syncytin-1 in human osteoclast fusion. Bone (2010) 1.13
Association of baseline levels of urinary glucosyl-galactosyl-pyridinoline and type II collagen C-telopeptide with progression of joint destruction in patients with early rheumatoid arthritis. Arthritis Rheum (2002) 1.12
Post-translational modifications of proteins: implications for aging, antigen recognition, and autoimmunity. Biogerontology (2004) 1.11
Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice. Clin Cancer Res (2002) 1.11
Associations between aortic calcification and components of body composition in elderly men. Obesity (Silver Spring) (2006) 1.11
The implications of body fat mass and fat distribution for cognitive function in elderly women. Obes Res (2004) 1.09
Differential activation of spinal cord glial cells in murine models of neuropathic and cancer pain. Eur J Pain (2008) 1.09
Effects of ovariectomy and estrogen therapy on type II collagen degradation and structural integrity of articular cartilage in rats: implications of the time of initiation. Arthritis Rheum (2006) 1.08
The relative use of eight collagenous and noncollagenous markers for diagnosis of skeletal metastases in breast, prostate, or lung cancer patients. Cancer Epidemiol Biomarkers Prev (2006) 1.08
The long-term predictive value of bone mineral density measurements for fracture risk is independent of the site of measurement and the age at diagnosis: results from the Prospective Epidemiological Risk Factors study. Osteoporos Int (2005) 1.06
New serum biochemical markers (Coll 2-1 and Coll 2-1 NO2) for studying oxidative-related type II collagen network degradation in patients with osteoarthritis and rheumatoid arthritis. Osteoarthritis Cartilage (2005) 1.06
The chloride channel inhibitor NS3736 [corrected] prevents bone resorption in ovariectomized rats without changing bone formation. J Bone Miner Res (2004) 1.06
Non-enzymatic covalent modifications of proteins: mechanisms, physiological consequences and clinical applications. Matrix Biol (2002) 1.04
Leptin receptor genotype at Gln223Arg is associated with body composition, BMD, and vertebral fracture in postmenopausal Danish women. J Bone Miner Res (2007) 1.02
Gonadotropin-releasing hormone blockers and cardiovascular disease risk: analysis of prospective clinical trials of degarelix. J Urol (2011) 1.00
Action of matrix metalloproteinases at restricted sites in colon anastomosis repair: an immunohistochemical and biochemical study. Surgery (2006) 0.99
Oral salmon calcitonin induced suppression of urinary collagen type II degradation in postmenopausal women: a new potential treatment of osteoarthritis. Bone (2005) 0.99
Variations in percentage of body fat within different BMI groups in young, middle-aged and old women. Clin Physiol Funct Imaging (2003) 0.97
Strontium diibuprofenate dihydrate, strontium malonate sesquihydrate, strontium diascorbate dihydrate and strontium 2-oxidobenzoate hydrate at 120 K. Acta Crystallogr C (2006) 0.97
Matrix metalloproteinase-12 (MMP-12) in osteoclasts: new lesson on the involvement of MMPs in bone resorption. Bone (2004) 0.96
Quantitative vertebral morphometry using neighbor-conditional shape models. Med Image Comput Comput Assist Interv (2006) 0.92
Biglycan deficiency increases osteoclast differentiation and activity due to defective osteoblasts. Bone (2005) 0.91
Biglycan deficiency interferes with ovariectomy-induced bone loss. J Bone Miner Res (2003) 0.90
Estrogen inhibits Dlk1/FA1 production: a potential mechanism for estrogen effects on bone turnover. J Bone Miner Res (2011) 0.89
Doxycycline-coated sutures improve mechanical strength of intestinal anastomoses. Int J Colorectal Dis (2007) 0.89
First-line treatment with bortezomib rapidly stimulates both osteoblast activity and bone matrix deposition in patients with multiple myeloma, and stimulates osteoblast proliferation and differentiation in vitro. Eur J Haematol (2010) 0.89
Optimising antiresorptive therapies in postmenopausal women: why do we need to give due consideration to the degree of suppression? Drugs (2006) 0.88
The response to oestrogen deprivation of the cartilage collagen degradation marker, CTX-II, is unique compared with other markers of collagen turnover. Arthritis Res Ther (2009) 0.87
An assessment of ADAMs in bone cells: absence of TACE activity prevents osteoclast recruitment and the formation of the marrow cavity in developing long bones. FEBS Lett (2003) 0.87
Premature loss of bone remodeling compartment canopies is associated with deficient bone formation: a study of healthy individuals and patients with Cushing's syndrome. J Bone Miner Res (2012) 0.87
Can we apply results from large to small arteries? Circ Res (2002) 0.87
The distribution pattern of critically short telomeres in human osteoarthritic knees. Arthritis Res Ther (2012) 0.87
Chronic administration of the selective P2X3, P2X2/3 receptor antagonist, A-317491, transiently attenuates cancer-induced bone pain in mice. Eur J Pharmacol (2012) 0.87
Multiple myeloma: changes in serum C-terminal telopeptide of collagen type I and bone-specific alkaline phosphatase can be used in daily practice to detect imminent osteolysis. Eur J Haematol (2010) 0.87
Endothelin 1 promotes osteoarthritic cartilage degradation via matrix metalloprotease 1 and matrix metalloprotease 13 induction. Arthritis Rheum (2003) 0.86
Estrogen receptor alpha and risk for cognitive impairment in postmenopausal women. Psychiatr Genet (2006) 0.86
Cartilage destruction in collagen induced arthritis assessed with a new biochemical marker for collagen type II C-telopeptide fragments. J Rheumatol (2004) 0.86
Ca2+-activated K+ channels in the endothelial cell layer involved in modulation of neurogenic contractions in rat penile arteries. Eur J Pharmacol (2003) 0.86
An immunoassay for measuring fragments of newly synthesized collagen type I produced during metastatic invasion of bone. Clin Lab (2004) 0.85
Nonselective matrix metalloproteinase but not tumor necrosis factor-α inhibition effectively preserves the early critical colon anastomotic integrity. Int J Colorectal Dis (2010) 0.84
Alpha CTX as a biomarker of skeletal invasion of breast cancer: immunolocalization and the load dependency of urinary excretion. Cancer Epidemiol Biomarkers Prev (2006) 0.84
The bone resorption inhibitors odanacatib and alendronate affect post-osteoclastic events differently in ovariectomized rabbits. Calcif Tissue Int (2013) 0.84
Steering the osteoclast through the demineralization-collagenolysis balance. Bone (2013) 0.84
Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain. Pharmacol Biochem Behav (2008) 0.84
The role of purinergic receptors in cancer-induced bone pain. J Osteoporos (2012) 0.83
The effect on cartilage of different forms of application of postmenopausal estrogen therapy: comparison of oral and transdermal therapy. Bone (2004) 0.83
Osteoclast fusion is based on heterogeneity between fusion partners. Calcif Tissue Int (2014) 0.83
Can the obesity paradox be explained by the protective effects of peripheral adiposity? Arch Intern Med (2005) 0.83
Uncoupling of collagen II metabolism in newly diagnosed, untreated rheumatoid arthritis is linked to inflammation and antibodies against cyclic citrullinated peptides. J Rheumatol (2010) 0.82
Glucocorticoids maintain human osteoclasts in the active mode of their resorption cycle. J Bone Miner Res (2010) 0.81
Pathogenic autoreactive B cells are not negatively selected toward matrix protein collagen II. J Immunol (2011) 0.81
Glucocorticoid-induced changes in the geometry of osteoclast resorption cavities affect trabecular bone stiffness. Calcif Tissue Int (2012) 0.81
Degarelix, a novel GnRH antagonist, causes minimal histamine release compared with cetrorelix, abarelix and ganirelix in an ex vivo model of human skin samples. Br J Clin Pharmacol (2010) 0.80
Palladium-catalyzed synthesis of aromatic carboxylic acids with silacarboxylic acids. Org Lett (2013) 0.80
Quantitative vertebral morphometry using neighbor-conditional shape models. Med Image Anal (2007) 0.80
Influence of sex differences on the progression of cancer-induced bone pain. Anticancer Res (2013) 0.79
Birth weight and adult bone metabolism are unrelated: results from birth weight-discordant monozygotic twins. J Bone Miner Res (2013) 0.78
Characterization of aged osteocalcin fragments derived from bone resorption. Clin Lab (2004) 0.78
Potential of resveratrol analogues as antagonists of osteoclasts and promoters of osteoblasts. Calcif Tissue Int (2010) 0.78
Application of inductively coupled plasma-mass spectrometry (ICP-MS) and quality assurance to study the incorporation of strontium into bone, bone marrow, and teeth of dogs after one month of treatment with strontium malonate. Anal Bioanal Chem (2008) 0.78
Cancer-induced bone loss and associated pain-related behavior is reduced by risedronate but not its phosphonocarboxylate analog NE-10790. Int J Cancer (2009) 0.78
Early elevation in circulating levels of C-telopeptides of type II collagen predicts structural damage in articular cartilage in the rodent model of collagen-induced arthritis. Arthritis Rheum (2006) 0.77
Hormone replacement therapy, calcium and vitamin D3 versus calcium and vitamin D3 alone decreases markers of cartilage and bone metabolism in rheumatoid arthritis: a randomized controlled trial [ISRCTN46523456]. Arthritis Res Ther (2004) 0.77
Posttranslational Protein Modifications in Type 1 Diabetes - Genetic Studies with PCMT1, the Repair Enzyme Protein Isoaspartate Methyltransferase (PIMT) Encoding Gene. Rev Diabet Stud (2009) 0.77
Quantifying calcification in the lumbar aorta on X-ray images. Med Image Comput Comput Assist Interv (2007) 0.77
Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain. Mol Pain (2013) 0.77
Breast cancer patients with bone metastases are characterised by increased levels of nonisomerised type I collagen fragments. Breast Cancer Res (2003) 0.76
Obesity susceptibility CART gene polymorphism contributes to bone remodeling in postmenopausal women. Osteoporos Int (2006) 0.76
Dosing related effects of zoledronic acid on bone markers and creatinine clearance in patients with multiple myeloma and metastatic breast cancer. Acta Oncol (2013) 0.76
Long-term risk of malignant neoplasm associated with gestational glucose intolerance. Cancer (2004) 0.75
Can confounding with fat-derived endogenous free estradiol explain the inverse correlation of bone mineral density with adiponectin? Bone (2004) 0.75
Cognitive impairment in elderly women: the relative importance of selected genes, lifestyle factors, and comorbidities. Neuropsychiatr Dis Treat (2006) 0.75
Correction: Bone Canopies in Pediatric Renal Osteodystrophy. PLoS One (2016) 0.75
Metabolite profiles of degarelix, a new gonadotropin-releasing hormone receptor antagonist, in rat, dog, and monkey. Drug Metab Dispos (2011) 0.75