Published in J Am Chem Soc on April 21, 2004
Expedient Access to 2,3-Dihydropyridines from Unsaturated Oximes by Rh(III)-Catalyzed C-H Activation. J Am Chem Soc (2015) 0.86
Total synthesis of (+/-)-symbioimine. Org Lett (2006) 0.84
Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins. Nat Prod Rep (2015) 0.83
Exploratory research on bioactive natural products with a focus on biological phenomena. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.75
De novo transcriptome of the cosmopolitan dinoflagellate Amphidinium carterae to identify enzymes with biotechnological potential. Sci Rep (2017) 0.75
FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases. Cancer Res (2002) 2.90
The calcineurin/nuclear factor of activated T cells signaling pathway regulates osteoclastogenesis in RAW264.7 cells. J Biol Chem (2004) 1.94
Specific inhibition of hepatitis C virus replication by cyclosporin A. Biochem Biophys Res Commun (2004) 1.93
Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins. Gastroenterology (2005) 1.85
Negative regulation of intracellular hepatitis C virus replication by interferon regulatory factor 3. J Gastroenterol (2006) 1.41
Antisense reduction of tau in adult mice protects against seizures. J Neurosci (2013) 1.29
Major involvement of low-density lipoprotein receptor-related protein 1 in the clearance of plasma free amyloid beta-peptide by the liver. Pharm Res (2006) 1.28
Blarina toxin, a mammalian lethal venom from the short-tailed shrew Blarina brevicauda: Isolation and characterization. Proc Natl Acad Sci U S A (2004) 1.16
Suppression of osteoprotegerin expression by prostaglandin E2 is crucially involved in lipopolysaccharide-induced osteoclast formation. J Immunol (2004) 1.15
Stereochemistry of pteriatoxins A, B, and C. J Am Chem Soc (2006) 1.14
Complanine, an inflammation-inducing substance isolated from the marine fireworm Eurythoe complanata. Org Biomol Chem (2008) 1.14
Generation of hydrogen peroxide primarily contributes to the induction of Fe(II)-dependent apoptosis in Jurkat cells by (-)-epigallocatechin gallate. Carcinogenesis (2004) 1.13
Effects of astaxanthin in obese mice fed a high-fat diet. Biosci Biotechnol Biochem (2007) 1.13
Self-assembling of guanidine-type surfactant. Langmuir (2008) 1.12
Fenton reaction is primarily involved in a mechanism of (-)-epigallocatechin-3-gallate to induce osteoclastic cell death. Biochem Biophys Res Commun (2002) 1.07
Magnolol enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells. Life Sci (2009) 1.04
Lipopolysaccharide supports survival and fusion of preosteoclasts independent of TNF-alpha, IL-1, and RANKL. J Cell Physiol (2002) 1.02
Free radical scavenging and hepatoprotective actions of the medicinal herb, Crassocephalum crepidioides from the Okinawa Islands. Biol Pharm Bull (2005) 1.01
Symbioimine and neosymbioimine, amphoteric iminium metabolites from the symbiotic marine dinoflagellate Symbiodinium sp. Bioorg Med Chem (2005) 0.97
Preparation of quinoline hexose analogs as novel chloroquine-resistant malaria treatments (1). Synthesis of 4-hydroxyquinoline-beta-glucosides. Chem Pharm Bull (Tokyo) (2007) 0.97
Synthesis and structural revision of symbiodinolide C23-C34 fragment. J Org Chem (2009) 0.95
Enantioselective synthesis of the spirotetracyclic carbon core of mangicols by using a stereoselective transannular Diels-Alder strategy. Angew Chem Int Ed Engl (2004) 0.95
Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae. Tetrahedron Lett (2009) 0.94
Effects of Korean white ginseng extracts on obesity in high-fat diet-induced obese mice. Cytotechnology (2010) 0.93
Insulin-dependent adipogenesis in stromal ST2 cells derived from murine bone marrow. Biosci Biotechnol Biochem (2003) 0.92
Effects of astaxanthin supplementation on exercise-induced fatigue in mice. Biol Pharm Bull (2006) 0.92
Enantioselective synthesis of 15-epi-haterumalide NA methyl ester and revised structure of haterumalide NA. Org Lett (2003) 0.92
NPPC/NPR2 signaling is essential for oocyte meiotic arrest and cumulus oophorus formation during follicular development in the mouse ovary. Reproduction (2012) 0.91
Effects of fenugreek seeds (Trigonella foenum greaecum) extract on endurance capacity in mice. J Nutr Sci Vitaminol (Tokyo) (2006) 0.91
Stereoselective synthesis and absolute configuration of the C1'-C25' fragment of symbiodinolide. J Org Chem (2009) 0.90
Artepillin C, as a PPARγ ligand, enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells. Biochem Pharmacol (2011) 0.90
Water extract of Houttuynia cordata Thunb. leaves exerts anti-obesity effects by inhibiting fatty acid and glycerol absorption. J Nutr Sci Vitaminol (Tokyo) (2010) 0.89
Anti-hyperglycaemic effects of the Japanese red maple Acer pycnanthum and its constituents the ginnalins B and C. J Enzyme Inhib Med Chem (2010) 0.89
Quercetin, a flavonoid, inhibits the proliferation, differentiation, and mineralization of osteoblasts in vitro. Eur J Pharmacol (2004) 0.89
Curcumin inhibits the proliferation and mineralization of cultured osteoblasts. Eur J Pharmacol (2006) 0.89
Nobiletin improves obesity and insulin resistance in high-fat diet-induced obese mice. J Nutr Biochem (2012) 0.89
Synthetic approach to kendomycin: preparation of the C-glycosidic core. Chem Commun (Camb) (2004) 0.88
Haterumadysins A-D, sesquiterpenes from the Okinawan marine sponge Dysidea chlorea. J Nat Prod (2006) 0.88
Cardiovascular effects and lethality of venom from nematocysts of the box-jellyfish Chiropsalmus quadrigatus (Habu-kurage) in anaesthetized rats. Toxicon (2005) 0.88
Bioactive secondary metabolites from symbiotic marine dinoflagellates: symbiodinolide and durinskiols. Chem Rec (2010) 0.87
Whole structure-activity relationships of the fat-accumulation inhibitor (-)-ternatin: recognition of the importance of each amino acid residue. J Med Chem (2008) 0.87
Effects of a Citrus depressa Hayata (shiikuwasa) extract on obesity in high-fat diet-induced obese mice. Phytomedicine (2011) 0.87
Engineering the promiscuous racemase activity of an arylmalonate decarboxylase. Chemistry (2010) 0.86
N,N'-diphenethylurea isolated from Okinawan ascidian Didemnum molle enhances adipocyte differentiation in 3T3-L1 cells. J Antibiot (Tokyo) (2011) 0.85
Identification of proteins from venom of the paralytic spider wasp, Cyphononyx dorsalis. Insect Biochem Mol Biol (2007) 0.85
Inhibitory effects of bakuchiol, bavachin, and isobavachalcone isolated from Piper longum on melanin production in B16 mouse melanoma cells. Biosci Biotechnol Biochem (2010) 0.85
Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling. Biochem Biophys Res Commun (2011) 0.85
Nobiletin improves hyperglycemia and insulin resistance in obese diabetic ob/ob mice. Biochem Pharmacol (2010) 0.85
Purification and characterisation of blarinasin, a new tissue kallikrein-like protease from the short-tailed shrew Blarina brevicauda: comparative studies with blarina toxin. Biol Chem (2005) 0.85
Channel induction by palytoxin in yeast cells expressing Na+,K+-ATPase or its chimera with sarco/endoplasmic reticulum Ca2+-ATPase. FEBS Lett (2003) 0.84
Furosin, an ellagitannin, suppresses RANKL-induced osteoclast differentiation and function through inhibition of MAP kinase activation and actin ring formation. Biochem Biophys Res Commun (2004) 0.84
(-)-Complanine, an inflammatory substance of marine fireworm: a synthetic study. Beilstein J Org Chem (2009) 0.84
Prevalence of protozoa, viruses, coliphages and indicator bacteria in groundwater and river water in the Kathmandu Valley, Nepal. Trans R Soc Trop Med Hyg (2011) 0.83
Neocomplanines A and B, a complanine family isolated from the marine fireworm. J Nat Prod (2010) 0.83
Duck-billed platypus venom peptides induce Ca2+ influx in neuroblastoma cells. J Am Chem Soc (2009) 0.83
Harmine, a β-carboline alkaloid, inhibits osteoclast differentiation and bone resorption in vitro and in vivo. Eur J Pharmacol (2010) 0.83
Tributyltin and triphenyltin inhibit osteoclast differentiation through a retinoic acid receptor-dependent signaling pathway. Biochem Biophys Res Commun (2007) 0.83
Suppressive effects of Anoectochilus formosanus extract on osteoclast formation in vitro and bone resorption in vivo. J Bone Miner Metab (2008) 0.83
Berberine enhances defects in the establishment of leaf polarity in asymmetric leaves1 and asymmetric leaves2 of Arabidopsis thaliana. Plant Mol Biol (2012) 0.83
Synthesis and biological activities of reveromycin A and spirofungin A derivatives. Bioorg Med Chem Lett (2008) 0.83
Inhibitory effect of luteolin on osteoclast differentiation and function. Cytotechnology (2010) 0.83
Discovery of novel rules for G-quadruplex-forming sequences in plants by using bioinformatics methods. J Biosci Bioeng (2012) 0.83
Coptisine inhibits RANKL-induced NF-κB phosphorylation in osteoclast precursors and suppresses function through the regulation of RANKL and OPG gene expression in osteoblastic cells. J Nat Med (2011) 0.82
Biselyngbyaside, isolated from marine cyanobacteria, inhibits osteoclastogenesis and induces apoptosis in mature osteoclasts. J Cell Biochem (2012) 0.82
Alisol-B, a novel phyto-steroid, suppresses the RANKL-induced osteoclast formation and prevents bone loss in mice. Biochem Pharmacol (2010) 0.82
Hepatoprotective effect of a hot-water extract from the edible thorny oyster Spondylus varius on carbon tetrachloride-induced liver injury in mice. Biosci Biotechnol Biochem (2006) 0.82
Potential anti-osteoporotic effects of herbal extracts on osteoclasts, osteoblasts and chondrocytes in vitro. BMC Complement Altern Med (2014) 0.82
Osteogenic activity of diphenyl ether-type cyclic diarylheptanoids derived from Acer nikoense. Bioorg Med Chem Lett (2011) 0.82
Identification of oxytetracycline as a chondrogenic compound using a cell-based screening system. J Bone Miner Metab (2010) 0.81
Honokiol inhibits osteoclast differentiation and function in vitro. Biol Pharm Bull (2010) 0.81
Effects of a selective cyclooxygenase-2 inhibitor, celecoxib, on bone resorption and osteoclastogenesis in vitro. Biochem Pharmacol (2002) 0.81
Molecular shape of palytoxin in aqueous solution. Org Biomol Chem (2007) 0.81
ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-beta peptide (1-40) at the blood-brain barrier. Neurochem Int (2007) 0.81
Honokiol and magnolol stimulate glucose uptake by activating PI3K-dependent Akt in L6 myotubes. Biofactors (2012) 0.81
Honokiol increases ABCA1 expression level by activating retinoid X receptor beta. Biol Pharm Bull (2010) 0.81
Halichlorine reduces monocyte adhesion to endothelium through the suppression of nuclear factor-kappaB activation. J Pharmacol Sci (2010) 0.80
Identification of two biologically crucial hydroxyl groups of (-)-epigallocatechin gallate in osteoclast culture. Biochem Pharmacol (2006) 0.80
Suppressive effects of the leaf of Terminalia catappa L. on osteoclast differentiation in vitro and bone weight loss in vivo. J Nutr Sci Vitaminol (Tokyo) (2012) 0.80
Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells. Biol Pharm Bull (2010) 0.80
Nobiletin and tangeretin ameliorate scratching behavior in mice by inhibiting the action of histamine and the activation of NF-κB, AP-1 and p38. Int Immunopharmacol (2013) 0.80
An inhibitory effect of chrysoeriol on platelet-derived growth factor (PDGF)-induced proliferation and PDGF receptor signaling in human aortic smooth muscle cells. J Pharmacol Sci (2009) 0.80
Honokiol enhances adipocyte differentiation by potentiating insulin signaling in 3T3-L1 preadipocytes. J Nat Med (2011) 0.80
Asymmetric total synthesis of pinnaic acid. Angew Chem Int Ed Engl (2007) 0.80
Peach leaf contains multiflorin a as a potent inhibitor of glucose absorption in the small intestine in mice. Biol Pharm Bull (2012) 0.79
Symbiospirols: novel long carbon-chain compounds isolated from symbiotic marine dinoflagellate Symbiodinium sp. Org Lett (2009) 0.79
Enantioselective total synthesis of pinnaic acid and halichlorine. Chem Asian J (2013) 0.79
Laminaria japonica as a food for the prevention of obesity and diabetes. Adv Food Nutr Res (2011) 0.79
Anti-inflammatory effects of seeds of the tropical fruit camu-camu (Myrciaria dubia). J Nutr Sci Vitaminol (Tokyo) (2011) 0.79
Lymphocyte and plasma vitamin C levels in type 2 diabetic patients with and without diabetes complications. Diabetes Care (2004) 0.79