Conducting research using the emergency exception from informed consent: the Public Access Defibrillation (PAD) Trial experience.

Burdens on research imposed by institutional review boards: the state of the evidence and its implications for regulatory reform. Milbank Q (2011) 2.29

Preliminary experience with social media for community consultation and public disclosure in exception from informed consent trials. Circulation (2013) 1.57

Why persons choose to opt out of an exception from informed consent cardiac arrest trial. Resuscitation (2013) 1.39

Regulatory challenges for the resuscitation outcomes consortium. Circulation (2008) 1.26

Emergency medical service providers' attitudes and experiences regarding enrolling patients in clinical research trials. Prehosp Emerg Care (2009) 1.25

Implementation of the exception from informed consent regulations in a large multicenter emergency clinical trials network: the RAMPART experience. Acad Emerg Med (2012) 1.23

Patients' perceptions of research in emergency settings: a study of survivors of sudden cardiac death. Soc Sci Med (2008) 1.14

A qualitative study of institutional review board members' experience reviewing research proposals using emergency exception from informed consent. J Med Ethics (2007) 0.92

Exploring ethical conflicts in emergency trauma research: the COMBAT (Control of Major Bleeding after Trauma) study experience. Surgery (2014) 0.82

Perceived challenges to obtaining informed consent for a time-sensitive emergency department study of pediatric status epilepticus: results of two focus groups. Acad Emerg Med (2009) 0.82

Variation of community consultation and public disclosure for a pediatric multi-centered "Exception from Informed Consent" trial. Clin Trials (2014) 0.79

Using social media for community consultation and public disclosure in exception from informed consent trials. J Trauma Acute Care Surg (2016) 0.75

Improving community understanding of medical research: audience response technology for community consultation for exception to informed consent. West J Emerg Med (2014) 0.75

Regional variation in out-of-hospital cardiac arrest incidence and outcome. JAMA (2008) 12.28

Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial. JAMA (2002) 6.75

Trial of Continuous or Interrupted Chest Compressions during CPR. N Engl J Med (2015) 6.66

The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study: approaches to control rate in atrial fibrillation. J Am Coll Cardiol (2004) 5.05

Part 1: executive summary: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 4.59

Ventricular tachyarrhythmias after cardiac arrest in public versus at home. N Engl J Med (2011) 4.26

Part 5: adult basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 4.16

Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study. Circulation (2004) 4.04

Emergency medical services intervals and survival in trauma: assessment of the "golden hour" in a North American prospective cohort. Ann Emerg Med (2009) 3.92

A trial of an impedance threshold device in out-of-hospital cardiac arrest. N Engl J Med (2011) 3.76

Out-of-hospital administration of intravenous glucose-insulin-potassium in patients with suspected acute coronary syndromes: the IMMEDIATE randomized controlled trial. JAMA (2012) 3.41

Guidelines for field triage of injured patients. Recommendations of the National Expert Panel on Field Triage. MMWR Recomm Rep (2009) 2.91

Chest compression fraction determines survival in patients with out-of-hospital ventricular fibrillation. Circulation (2009) 2.89

Part 4: CPR overview: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 2.82

Chest compression rates and survival following out-of-hospital cardiac arrest. Crit Care Med (2015) 2.77

Family presence during brain death evaluation: a randomized controlled trial*. Crit Care Med (2014) 2.68

Cardiopulmonary resuscitation quality: [corrected] improving cardiac resuscitation outcomes both inside and outside the hospital: a consensus statement from the American Heart Association. Circulation (2013) 2.49

Early versus later rhythm analysis in patients with out-of-hospital cardiac arrest. N Engl J Med (2011) 2.45

Part 3: ethics: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation (2010) 2.41

No assisted ventilation cardiopulmonary resuscitation and 24-hour neurological outcomes in a porcine model of cardiac arrest. Crit Care Med (2010) 2.39

Part 1: Executive summary: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation (2010) 2.31

Quality of life in atrial fibrillation: the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study. Am Heart J (2005) 2.31

Socioeconomic status and incidence of sudden cardiac arrest. CMAJ (2011) 2.31

Survival after application of automatic external defibrillators before arrival of the emergency medical system: evaluation in the resuscitation outcomes consortium population of 21 million. J Am Coll Cardiol (2010) 2.29

Relationship between chest compression rates and outcomes from cardiac arrest. Circulation (2012) 2.25

The out-of-hospital validation of the Canadian C-Spine Rule by paramedics. Ann Emerg Med (2009) 2.17

H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencing. Nat Struct Mol Biol (2007) 2.08

Emergency physicians' fear of malpractice in evaluating patients with possible acute cardiac ischemia. Ann Emerg Med (2005) 2.02

Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial. JAMA (2010) 2.00

Analysis of cause-specific mortality in the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study. Circulation (2004) 1.99

The impact of increased chest compression fraction on return of spontaneous circulation for out-of-hospital cardiac arrest patients not in ventricular fibrillation. Resuscitation (2011) 1.98

Examining the contextual effects of neighborhood on out-of-hospital cardiac arrest and the provision of bystander cardiopulmonary resuscitation. Resuscitation (2011) 1.94

Primary outcomes for resuscitation science studies: a consensus statement from the American Heart Association. Circulation (2011) 1.93

Effects of incomplete chest wall decompression during cardiopulmonary resuscitation on coronary and cerebral perfusion pressures in a porcine model of cardiac arrest. Resuscitation (2005) 1.89

The random dialing survey as a tool for community consultation for research involving the emergency medicine exception from informed consent. Ann Emerg Med (2008) 1.88

Percent right ventricular pacing predicts outcomes in the DAVID trial. Heart Rhythm (2005) 1.83

Regional systems of care for out-of-hospital cardiac arrest: A policy statement from the American Heart Association. Circulation (2010) 1.80

High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes. Nucleic Acids Res (2007) 1.80

Part 5: Adult basic life support: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation (2010) 1.80

Functional status in rate- versus rhythm-control strategies for atrial fibrillation: results of the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Functional Status Substudy. J Am Coll Cardiol (2005) 1.77

Manual chest compression vs use of an automated chest compression device during resuscitation following out-of-hospital cardiac arrest: a randomized trial. JAMA (2006) 1.77

Predicting survival after out-of-hospital cardiac arrest: role of the Utstein data elements. Ann Emerg Med (2009) 1.77

Alternative endpoints for mortality in studies of patients with atrial fibrillation: the AFFIRM study experience. Heart Rhythm (2004) 1.70

Confronting the Ethical Conduct of Resuscitation Research: a consensus opinion. Acad Emerg Med (2005) 1.68

Homeostatic regulation of supercoiling sensitivity coordinates transcription of the bacterial genome. EMBO Rep (2006) 1.66

Clinical and hemodynamic comparison of 15:2 and 30:2 compression-to-ventilation ratios for cardiopulmonary resuscitation. Crit Care Med (2006) 1.64

Reducing barriers for implementation of bystander-initiated cardiopulmonary resuscitation: a scientific statement from the American Heart Association for healthcare providers, policymakers, and community leaders regarding the effectiveness of cardiopulmonary resuscitation. Circulation (2008) 1.63

Attitudes of emergency department patients and visitors regarding emergency exception from informed consent in resuscitation research, community consultation, and public notification. Acad Emerg Med (2003) 1.63

Implementing the 2005 American Heart Association guidelines, including use of the impedance threshold device, improves hospital discharge rate after in-hospital cardiac arrest. Respir Care (2010) 1.63

Cardiac arrest survival did not increase in the Resuscitation Outcomes Consortium after implementation of the 2005 AHA CPR and ECC guidelines. Resuscitation (2011) 1.62

Survival increases with CPR by Emergency Medical Services before defibrillation of out-of-hospital ventricular fibrillation or ventricular tachycardia: observations from the Resuscitation Outcomes Consortium. Resuscitation (2009) 1.62

Take Heart America: A comprehensive, community-wide, systems-based approach to the treatment of cardiac arrest. Crit Care Med (2011) 1.61

Analysis of implantable cardioverter defibrillator therapy in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial. J Cardiovasc Electrophysiol (2003) 1.59

The legacy of the Tuskegee syphilis experiments for emergency exception from informed consent. Ann Emerg Med (2003) 1.55

Cost-effectiveness of rhythm versus rate control in atrial fibrillation. Ann Intern Med (2004) 1.52

Sodium nitroprusside-enhanced cardiopulmonary resuscitation improves resuscitation rates after prolonged untreated cardiac arrest in two porcine models. Crit Care Med (2011) 1.52

Reducing ventilation frequency during cardiopulmonary resuscitation in a porcine model of cardiac arrest. Respir Care (2005) 1.51

Association between Physician Orders for Life-Sustaining Treatment for Scope of Treatment and in-hospital death in Oregon. J Am Geriatr Soc (2014) 1.51

Variation in the type, rate, and selection of patients for out-of-hospital airway procedures among injured children and adults. Acad Emerg Med (2009) 1.46

Importance and implementation of training in cardiopulmonary resuscitation and automated external defibrillation in schools: a science advisory from the American Heart Association. Circulation (2011) 1.45

Gene order and chromosome dynamics coordinate spatiotemporal gene expression during the bacterial growth cycle. Proc Natl Acad Sci U S A (2011) 1.45

Level of concern and precaution taking among Australians regarding travel during pandemic (H1N1) 2009: results from the 2009 Queensland Social Survey. J Travel Med (2010) 1.44

Part 1: Executive summary: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Resuscitation (2010) 1.43

Cost-effectiveness of lay responder defibrillation for out-of-hospital cardiac arrest. Ann Emerg Med (2009) 1.42

Comparison of methods for the determination of cardiopulmonary resuscitation chest compression fraction. Resuscitation (2012) 1.40

Treatment of non-traumatic out-of-hospital cardiac arrest with active compression decompression cardiopulmonary resuscitation plus an impedance threshold device. Resuscitation (2013) 1.40

Factors affecting bleeding risk during anticoagulant therapy in patients with atrial fibrillation: observations from the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study. Am Heart J (2005) 1.40

Why persons choose to opt out of an exception from informed consent cardiac arrest trial. Resuscitation (2013) 1.39

Search is a time-critical event: when search and rescue missions may become futile. Wilderness Environ Med (2007) 1.39

Essential features of designating out-of-hospital cardiac arrest as a reportable event: a scientific statement from the American Heart Association Emergency Cardiovascular Care Committee; Council on Cardiopulmonary, Perioperative, and Critical Care; Council on Cardiovascular Nursing; Council on Clinical Cardiology; and Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation (2008) 1.38

The pre-hospital fibrinolysis experience in Europe and North America and implications for wider dissemination. JACC Cardiovasc Interv (2011) 1.38

ACC/AHA/HRS 2006 key data elements and definitions for electrophysiological studies and procedures: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (ACC/AHA/HRS Writing Committee to Develop Data Standards on Electrophysiology). Circulation (2006) 1.29

The National EMS Research Agenda executive summary. Emergency Medical Services. Ann Emerg Med (2002) 1.29

Effectiveness of a 30-min CPR self-instruction program for lay responders: a controlled randomized study. Resuscitation (2005) 1.28

Regulatory challenges for the resuscitation outcomes consortium. Circulation (2008) 1.26

Retention of CPR skills learned in a traditional AHA Heartsaver course versus 30-min video self-training: a controlled randomized study. Resuscitation (2007) 1.25

Executive summary: the 2005 AEM Consensus Conference on Ethical Conduct of Resuscitation Research. Acad Emerg Med (2005) 1.25

Career outcomes of the graduates of the American Board of Internal Medicine Research Pathway, 1995-2007. Acad Med (2013) 1.24

Level I versus Level II trauma centers: an outcomes-based assessment. J Trauma (2009) 1.23

Community consultation methods in a study using exception to informed consent. Prehosp Emerg Care (2008) 1.22

Scientific knowledge gaps and clinical research priorities for cardiopulmonary resuscitation and emergency cardiovascular care identified during the 2005 International Consensus Conference on ECC [corrected] and CPR science with treatment recommendations: a consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian Resuscitation Council, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, and the New Zealand Resuscitation Council); the American Heart Association Emergency Cardiovascular Care Committee; the Stroke Council; and the Cardiovascular Nursing Council.". Circulation (2007) 1.20

A conserved role but different partners for the transcriptional corepressor CoREST in fly and mammalian nervous system formation. J Neurosci (2004) 1.19

Pervasive regulation of nucleoid structure and function by nucleoid-associated proteins. Curr Opin Microbiol (2011) 1.19

Pulseless electric activity: definition, causes, mechanisms, management, and research priorities for the next decade: report from a National Heart, Lung, and Blood Institute workshop. Circulation (2013) 1.18

Underuse of prehospital strategies to reduce time to reperfusion for ST-elevation myocardial infarction patients in 5 Canadian provinces. CJEM (2009) 1.17

Remosomes: RSC generated non-mobilized particles with approximately 180 bp DNA loosely associated with the histone octamer. Proc Natl Acad Sci U S A (2010) 1.16

Left ventricular form and function: scientific priorities and strategic planning for development of new views of disease. Circulation (2004) 1.16

Emergency department treatment of viral gastritis using intravenous ondansetron or dexamethasone in children. Acad Emerg Med (2006) 1.16

Increasing cardiopulmonary resuscitation provision in communities with low bystander cardiopulmonary resuscitation rates: a science advisory from the American Heart Association for healthcare providers, policymakers, public health departments, and community leaders. Circulation (2013) 1.15

Increasing hospital volume is not associated with improved survival in out of hospital cardiac arrest of cardiac etiology. Resuscitation (2012) 1.15

Study design for the Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care (IMMEDIATE) Trial: A double-blind randomized controlled trial of intravenous glucose, insulin, and potassium for acute coronary syndromes in emergency medical services. Am Heart J (2012) 1.15

A meta-analysis of prehospital airway control techniques part II: alternative airway devices and cricothyrotomy success rates. Prehosp Emerg Care (2010) 1.14