Published in Cell Motil Cytoskeleton on June 01, 2004
Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nat Rev Mol Cell Biol (2010) 7.27
Nanoscale architecture of integrin-based cell adhesions. Nature (2010) 5.88
Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner. Nat Cell Biol (2008) 5.87
Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array. BMC Genomics (2006) 5.59
Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes. Proc Natl Acad Sci U S A (2007) 5.36
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nat Cell Biol (2011) 4.59
ADVANCED IMAGING. Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics. Science (2015) 4.12
Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner. J Clin Invest (2005) 2.39
Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction. Am J Physiol Cell Physiol (2008) 2.24
Structural dynamics of alpha-actinin-vinculin interactions. Mol Cell Biol (2005) 2.12
Alpha-actinin is required for tightly regulated remodeling of the actin cortical network during cytokinesis. Dev Cell (2007) 2.10
Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesions. Curr Biol (2014) 1.75
The vertebrate muscle Z-disc: sarcomere anchor for structure and signalling. J Muscle Res Cell Motil (2009) 1.70
A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle. J Cell Biol (2007) 1.60
Disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity. Proc Natl Acad Sci U S A (2007) 1.53
ACTN1 mutations cause congenital macrothrombocytopenia. Am J Hum Genet (2013) 1.49
Targets of caspase-6 activity in human neurons and Alzheimer disease. Mol Cell Proteomics (2008) 1.48
An equatorial contractile mechanism drives cell elongation but not cell division. PLoS Biol (2014) 1.45
Intermediate-affinity LFA-1 binds alpha-actinin-1 to control migration at the leading edge of the T cell. EMBO J (2007) 1.39
CaMKII: claiming center stage in postsynaptic function and organization. Neuron (2014) 1.39
Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology. PLoS One (2009) 1.34
Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells. J Cell Biol (2008) 1.25
The role of palladin in actin organization and cell motility. Eur J Cell Biol (2008) 1.22
α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction. J Cell Biol (2012) 1.22
Dynamic association between alpha-actinin and beta-integrin regulates contraction of canine tracheal smooth muscle. J Physiol (2006) 1.15
Investigating complexity of protein-protein interactions in focal adhesions. Biochem Biophys Res Commun (2008) 1.11
α-actinin-4 is essential for maintaining the spreading, motility and contractility of fibroblasts. PLoS One (2010) 1.11
Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators. Mol Biol Cell (2012) 1.10
Alpha-actinin binding kinetics modulate cellular dynamics and force generation. Proc Natl Acad Sci U S A (2015) 1.10
The NPIY motif in the integrin beta1 tail dictates the requirement for talin-1 in outside-in signaling. J Cell Sci (2010) 1.10
Palladin interacts with SH3 domains of SPIN90 and Src and is required for Src-induced cytoskeletal remodeling. Exp Cell Res (2007) 1.09
Novel structures for alpha-actinin:F-actin interactions and their implications for actin-membrane attachment and tension sensing in the cytoskeleton. J Mol Biol (2007) 1.09
Functions of nonmuscle myosin II in assembly of the cellular contractile system. PLoS One (2012) 1.08
Photoactivated localization microscopy (PALM) of adhesion complexes. Curr Protoc Cell Biol (2008) 1.06
Autoantibodies and resident renal cells in the pathogenesis of lupus nephritis: getting to know the unknown. Clin Dev Immunol (2012) 1.05
easyExon--a Java-based GUI tool for processing and visualization of Affymetrix exon array data. BMC Bioinformatics (2008) 1.05
The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges. J Biol Chem (2008) 1.03
Phosphorylation of alpha-actinin 4 upon epidermal growth factor exposure regulates its interaction with actin. J Biol Chem (2009) 1.03
Mechanisms of talin-dependent integrin signaling and crosstalk. Biochim Biophys Acta (2013) 1.03
Cytoplasmic Ig-domain proteins: cytoskeletal regulators with a role in human disease. Cell Motil Cytoskeleton (2009) 1.02
Cell-matrix adhesion of podocytes in physiology and disease. Nat Rev Nephrol (2013) 1.02
Changes in gene expression and cellular architecture in an ovarian cancer progression model. PLoS One (2011) 1.01
The actin-binding protein, actinin alpha 4 (ACTN4), is a nuclear receptor coactivator that promotes proliferation of MCF-7 breast cancer cells. J Biol Chem (2010) 1.00
UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) binds to alpha-actinin 1: novel pathways in skeletal muscle? PLoS One (2008) 0.98
Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions. Mol Cell Biol (2008) 0.97
Regulation of TGF-beta1/MAPK-mediated PAI-1 gene expression by the actin cytoskeleton in human mesangial cells. Exp Cell Res (2007) 0.96
Ultrastructural localization of actin and actin-binding proteins in the nucleus. Histochem Cell Biol (2008) 0.93
Identification of a novel LXXLL motif in α-actinin 4-spliced isoform that is critical for its interaction with estrogen receptor α and co-activators. J Biol Chem (2012) 0.93
Neisseria meningitidis Opc invasin binds to the cytoskeletal protein alpha-actinin. Cell Microbiol (2008) 0.93
Crystal structure of the actin-binding domain of alpha-actinin-4 Lys255Glu mutant implicated in focal segmental glomerulosclerosis. J Mol Biol (2007) 0.93
Mechanotransduction at focal adhesions: integrating cytoskeletal mechanics in migrating cells. J Cell Mol Med (2013) 0.92
MICAL-family proteins: Complex regulators of the actin cytoskeleton. Antioxid Redox Signal (2013) 0.92
Sacs knockout mice present pathophysiological defects underlying autosomal recessive spastic ataxia of Charlevoix-Saguenay. Hum Mol Genet (2014) 0.91
The cytoskeletal protein alpha-actinin regulates acid-sensing ion channel 1a through a C-terminal interaction. J Biol Chem (2008) 0.91
Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis. Arthritis Res Ther (2006) 0.90
Stage-specific regulation of adhesion molecule expression segregates epithelial stem/progenitor cells in fetal and adult human livers. Hepatol Int (2007) 0.90
Combinatorial morphogenesis of dendritic spines and filopodia by SPAR and alpha-actinin2. Biochem Biophys Res Commun (2009) 0.89
A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells. J Cell Sci (2013) 0.89
The role of alpha-actinin-4 in human kidney disease. Cell Biosci (2015) 0.89
The biological role of actinin-4 (ACTN4) in malignant phenotypes of cancer. Cell Biosci (2015) 0.89
Remodeling of the sarcomeric cytoskeleton in cardiac ventricular myocytes during heart failure and after cardiac resynchronization therapy. J Mol Cell Cardiol (2014) 0.89
Downregulation of thrombomodulin, a novel target of Snail, induces tumorigenesis through epithelial-mesenchymal transition. Mol Cell Biol (2010) 0.88
Analysis of tarantula skeletal muscle protein sequences and identification of transcriptional isoforms. BMC Genomics (2009) 0.88
Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors. J Biol Chem (2012) 0.87
Regulation of structure and function of sarcomeric actin filaments in striated muscle of the nematode Caenorhabditis elegans. Anat Rec (Hoboken) (2014) 0.87
Tyrosine phosphorylation of CD13 regulates inflammatory cell-cell adhesion and monocyte trafficking. J Immunol (2013) 0.87
The switch-associated protein 70 (SWAP-70) bundles actin filaments and contributes to the regulation of F-actin dynamics. J Biol Chem (2013) 0.87
Cytoskeletal proteins in cortical development and disease: actin associated proteins in periventricular heterotopia. Front Cell Neurosci (2015) 0.86
Combining mechanical and optical approaches to dissect cellular mechanobiology. J Biomech (2009) 0.86
α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms. FASEB J (2012) 0.86
Translational strategies for neuroprotection in ischemic stroke--focusing on acid-sensing ion channel 1a. Transl Stroke Res (2014) 0.86
A strategy for full interrogation of prognostic gene expression patterns: exploring the biology of diffuse large B cell lymphoma. PLoS One (2011) 0.86
ACTN4 copy number increase as a predictive biomarker for chemoradiotherapy of locally advanced pancreatic cancer. Br J Cancer (2015) 0.85
Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction. Biochemistry (2010) 0.85
Podocyte-actin dynamics in health and disease. Nat Rev Nephrol (2016) 0.85
Contributions of talin-1 to glioma cell-matrix tensional homeostasis. J R Soc Interface (2011) 0.84
Targeted proteomics of isolated glomeruli from the kidneys of diabetic rats: sorbin and SH3 domain containing 2 is a novel protein associated with diabetic nephropathy. Exp Diabetes Res (2011) 0.84
A molecular trajectory of α-actinin activation. Biophys J (2012) 0.84
alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering. Mol Brain (2008) 0.84
The actinin family of actin cross-linking proteins - a genetic perspective. Cell Biosci (2015) 0.84
α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation. Exp Cell Res (2013) 0.83
Contribution of Filopodia to Cell Migration: A Mechanical Link between Protrusion and Contraction. Int J Cell Biol (2010) 0.83
Deposition of nonsarcomeric alpha-actinin in cardiomyocytes from patients with dilated cardiomyopathy or chronic pressure overload. Exp Clin Cardiol (2009) 0.83
Animal models of muscular dystrophy. Prog Mol Biol Transl Sci (2012) 0.83
The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain. J Cell Sci (2011) 0.83
LPS-induced genes in intestinal tissue of the sea cucumber Holothuria glaberrima. PLoS One (2009) 0.83
Rab13 small G protein and junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development. J Biol Chem (2012) 0.83
The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3. Mol Cancer (2008) 0.82
Sequence and expression of the zebrafish alpha-actinin gene family reveals conservation and diversification among vertebrates. Dev Dyn (2009) 0.82
Meta-analysis and profiling of cardiac expression modules. Physiol Genomics (2008) 0.82
Double reactivity against actin and alpha-actinin defines a severe form of autoimmune hepatitis type 1. J Clin Immunol (2006) 0.82
Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development. PLoS Genet (2015) 0.82
Structural characterization of the interactions between palladin and α-actinin. J Mol Biol (2011) 0.81
Differential proteomics in the aging Noble rat ventral prostate. Proteomics (2008) 0.81
Actin-associated Proteins in the Pathogenesis of Podocyte Injury. Curr Genomics (2013) 0.81
The carboxyl tail of alpha-actinin-4 regulates its susceptibility to m-calpain and thus functions in cell migration and spreading. Int J Biochem Cell Biol (2013) 0.81
Synaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturation. J Cell Biol (2015) 0.80
Podocyte Injury Associated with Mutant α-Actinin-4. J Signal Transduct (2011) 0.80
HAMLET binding to α-actinin facilitates tumor cell detachment. PLoS One (2011) 0.80
Evaluation of antiviral activities of four local Malaysian Phyllanthus species against herpes simplex viruses and possible antiviral target. Int J Med Sci (2013) 0.80
Human rhinovirus in bronchial epithelium of infants with recurrent respiratory symptoms. J Allergy Clin Immunol (2006) 1.68
The palladin/myotilin/myopalladin family of actin-associated scaffolds. Int Rev Cytol (2005) 1.35
A class III PDZ binding motif in the myotilin and FATZ families binds enigma family proteins: a common link for Z-disc myopathies. Mol Cell Biol (2008) 1.17
The proline-rich protein palladin is a binding partner for profilin. FEBS J (2006) 1.17
Palladin interacts with SH3 domains of SPIN90 and Src and is required for Src-induced cytoskeletal remodeling. Exp Cell Res (2007) 1.09
The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins. J Cell Sci (2005) 1.08
Involvement of palladin and alpha-actinin in targeting of the Abl/Arg kinase adaptor ArgBP2 to the actin cytoskeleton. Exp Cell Res (2005) 1.07
Analysis of cyclins A, B1, D1 and E in breast cancer in relation to tumour grade and other prognostic factors. BMC Res Notes (2009) 1.03
Ezrin in primary cutaneous melanoma. Mod Pathol (2005) 0.99
Ovarian carcinoma histotype determination is highly reproducible, and is improved through the use of immunohistochemistry. Histopathology (2014) 0.95
Telethonin protein expression in neuromuscular disorders. Biochim Biophys Acta (2002) 0.95
Myotilinopathy in a family with late onset myopathy. Neuromuscul Disord (2006) 0.92
Distribution of prolyl oligopeptidase in human peripheral tissues and in ovarian and colorectal tumors. J Histochem Cytochem (2012) 0.89
Different early pathogenesis in myotilinopathy compared to primary desminopathy. Neuromuscul Disord (2006) 0.86
Palladin promotes assembly of non-contractile dorsal stress fibers through VASP recruitment. J Cell Sci (2014) 0.84
Analysis of myotilin turnover provides mechanistic insight into the role of myotilinopathy-causing mutations. Biochem J (2011) 0.83
Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting. Acta Neuropathol (2011) 0.83
Detection of rhinovirus RNA in middle turbinate of patients with common colds by in situ hybridization. J Med Virol (2003) 0.80
Serum HE4 Profile During Primary Chemotherapy of Epithelial Ovarian Cancer. Int J Gynecol Cancer (2011) 0.80
Expression of ezrin, Bcl-2, and Ki-67 in chondrosarcomas. APMIS (2010) 0.76
A Selective Biomarker Panel Increases the Reproducibility and the Accuracy in Endometrial Biopsy Diagnosis. Int J Gynecol Pathol (2017) 0.75