Published in Eur J Pharmacol on April 12, 2004
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes. Proc Natl Acad Sci U S A (2008) 1.93
G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension. Hypertension (2012) 1.59
Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6. Blood (2009) 1.44
GRK2 as a novel gene therapy target in heart failure. J Mol Cell Cardiol (2010) 1.31
G protein-coupled receptor kinases in normal and failing myocardium. Front Biosci (Landmark Ed) (2011) 1.17
G protein coupled receptor kinases as therapeutic targets in cardiovascular disease. Circ Res (2011) 1.14
Nuclear effects of G-protein receptor kinase 5 on histone deacetylase 5-regulated gene transcription in heart failure. Circ Heart Fail (2011) 1.12
Determining the absolute requirement of G protein-coupled receptor kinase 5 for pathological cardiac hypertrophy: short communication. Circ Res (2012) 1.09
Gi-biased β2AR signaling links GRK2 upregulation to heart failure. Circ Res (2011) 1.01
Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process. PLoS One (2013) 0.97
The evolving impact of g protein-coupled receptor kinases in cardiac health and disease. Physiol Rev (2015) 0.97
GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans. Pharmacogenomics (2009) 0.87
G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression. J Biol Chem (2012) 0.85
GRK5-mediated exacerbation of pathological cardiac hypertrophy involves facilitation of nuclear NFAT activity. Circ Res (2014) 0.83
GRK2 and β-arrestins in cardiovascular disease: Something old, something new. Am J Cardiovasc Dis (2011) 0.81
Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases. Nat Commun (2016) 0.80
"Canonical and non-canonical actions of GRK5 in the heart". J Mol Cell Cardiol (2016) 0.78
GRK2 in the heart: a GPCR kinase and beyond. Antioxid Redox Signal (2014) 0.78
Heart failure-specific changes in protein kinase signalling. Pflugers Arch (2014) 0.78
G protein-coupled receptor kinase 5: exploring its hype in cardiac hypertrophy. Circ Res (2012) 0.75
The expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development. Pharmacol Res (2016) 0.75
G protein-coupled Receptor Kinase 2 as a Therapeutic Target for Heart Failure. Drug Discov Today Ther Strateg (2012) 0.75
Surgical strategy to establish a dual-coronary system for the management of anomalous left coronary artery origin from the pulmonary artery. Ann Thorac Surg (2008) 1.60
Results of rapid-response extracorporeal cardiopulmonary resuscitation in children with refractory cardiac arrest following cardiac surgery. Eur J Cardiothorac Surg (2013) 1.45
The Ross procedure in children: preoperative haemodynamic manifestation has significant effect on late autograft re-operation. Eur J Cardiothorac Surg (2010) 1.42
Cardiac reoperations following the Ross procedure in children: spectrum of surgery and reoperation results. Eur J Cardiothorac Surg (2012) 1.39
The improvement of care for paediatric and congenital cardiac disease across the World: a challenge for the World Society for Pediatric and Congenital Heart Surgery. Cardiol Young (2008) 1.04
Characterization of lymphocyte beta 2-adrenoceptor signalling in patients with left ventricular volume overload disease. Clin Exp Pharmacol Physiol (2002) 0.99
Left ventricular global transcriptional profiling in human end-stage dilated cardiomyopathy. Genomics (2009) 0.98
A study of the role of the Myocyte-specific Enhancer Factor-2A gene in coronary artery disease. Atherosclerosis (2009) 0.90
Pregnancy has no effect on the rate of structural deterioration of bioprosthetic valves: long-term 18-year follow up results. J Heart Valve Dis (2005) 0.89
The rastelli procedure for transposition of the great arteries: resection of the infundibular septum diminishes recurrent left ventricular outflow tract obstruction risk. Ann Thorac Surg (2009) 0.88
Outcomes of Damus-Kaye-Stansel anastomosis at time of cavopulmonary connection in single ventricle patients at risk of developing systemic ventricular outflow tract obstruction. Eur J Cardiothorac Surg (2013) 0.86
Association of the angiotensinogen gene polymorphism with atherosclerosis and its risk traits in the Saudi population. BMC Cardiovasc Disord (2013) 0.86
Current outcomes of the Glenn bidirectional cavopulmonary connection for single ventricle palliation. Eur J Cardiothorac Surg (2012) 0.86
Results after mitral valve replacement with mechanical prostheses in young children. J Thorac Cardiovasc Surg (2010) 0.85
Does single ventricle physiology affect survival of children requiring extracorporeal membrane oxygenation support following cardiac surgery? World J Pediatr Congenit Heart Surg (2014) 0.84
Superior results following the Ross procedure in patients with congenital heart disease. J Heart Valve Dis (2010) 0.82
Myocardial hypertrophy is not a prerequisite for changes in early gene expression in left ventricular volume overload. Fundam Clin Pharmacol (2004) 0.82
The 3'-UTR of the adiponectin Q gene harbours susceptibility loci for atherosclerosis and its metabolic risk traits. BMC Med Genet (2013) 0.81
New susceptibility locus for obesity and dyslipidaemia on chromosome 3q22.3. Hum Genomics (2013) 0.80
Older children at the time of the Norwood operation have ongoing mortality vulnerability that continues after cavopulmonary connection. J Thorac Cardiovasc Surg (2011) 0.80
Determinants of short- and long-term outcomes following triple valve surgery. J Heart Valve Dis (2010) 0.80
Fontan completion without surgery. Eur J Cardiothorac Surg (2007) 0.79
Haplotypes encompassing the KIAA0391 and PSMA6 gene cluster confer a genetic link for myocardial infarction and coronary artery disease. Ann Hum Genet (2009) 0.79
Aortic and mitral valve replacement in children: is there any role for biologic and bioprosthetic substitutes? Eur J Cardiothorac Surg (2009) 0.78
Repair of atrioventricular valve regurgitation in the modified Fontan operation. Eur J Cardiothorac Surg (2004) 0.77
A study of the role of GATA4 polymorphism in cardiovascular metabolic disorders. Hum Genomics (2013) 0.77
Mechanical valves versus the Ross procedure for aortic valve replacement in children: propensity-adjusted comparison of long-term outcomes. J Thorac Cardiovasc Surg (2009) 0.76
Outcomes and associated risk factors for mitral valve replacement in children. Eur J Cardiothorac Surg (2011) 0.76
Hybrid management strategy for percutaneous Fontan completion without surgery: early results. Ann Thorac Surg (2011) 0.75
The fate of the neoaortic valve and root after the modified Ross-Konno procedure. J Thorac Cardiovasc Surg (2012) 0.75
An invitation to the medical students of the world to join the global coalition to improve care for children and adults with congenital heart disease across the world. Mcgill J Med (2008) 0.75
Assessment of the standard pediatric unfractionated heparin dosing protocol. Asian Cardiovasc Thorac Ann (2012) 0.75
Results of left atrioventricular valve reoperations following previous repair of atrioventricular septal defects. J Card Surg (2009) 0.75
The radial artery as a coronary bypass conduit: dealing with hypereactivity. Ann Saudi Med (2005) 0.75
Intermediate results following complex biventricular repair of left ventricular outflow tract obstruction in neonates and infants. Eur J Cardiothorac Surg (2010) 0.75
Is the ross procedure a suitable choice for aortic valve replacement in children with rheumatic aortic valve disease? World J Pediatr Congenit Heart Surg (2012) 0.75
Mitral valve replacement with the Quattro stentless pericardial bioprosthesis: mid-term clinical and echocardiographic follow up. J Heart Valve Dis (2010) 0.75
Fate of the remaining neo-aortic root after autograft valve replacement with a stented prosthesis for the failing ross procedure. Ann Thorac Surg (2013) 0.75
Simultaneous aortic and mitral valve replacement in children: time-related outcomes and risk factors. J Heart Valve Dis (2010) 0.75
Exploring the role of cyclosporine in reducing homograft degeneration post-Ross. Asian Cardiovasc Thorac Ann (2010) 0.75
Atrial septal defect with drainage of the inferior vena cava into the left atrium. Eur J Cardiothorac Surg (2011) 0.75
Aortic pseudoaneurysm with fistulization into the pulmonary artery: a cause of refractory heart failure after bentall procedure. J Am Soc Echocardiogr (2007) 0.75