Published in Clin Cancer Res on April 15, 2004
Systems biology of cisplatin resistance: past, present and future. Cell Death Dis (2014) 1.74
Therapeutic Targeting of ATP7B in Ovarian Carcinoma. Clin Cancer Res (2009) 1.61
Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy. Lung Cancer (2011) 1.12
Novel strategies for reversing platinum resistance. Drug Resist Updat (2009) 1.00
Pharmacogenomics of platinum-based chemotherapy in NSCLC. Expert Opin Drug Metab Toxicol (2009) 0.97
The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy. Acta Pharmacol Sin (2013) 0.85
Pharmacogenomics of cisplatin sensitivity in non-small cell lung cancer. Genomics Proteomics Bioinformatics (2014) 0.85
Can pharmacogenetics explain efficacy and safety of cisplatin pharmacotherapy? Front Genet (2014) 0.83
Genetic variation in radiation and platinum pathways predicts severe acute radiation toxicity in patients with esophageal adenocarcinoma treated with cisplatin-based preoperative radiochemotherapy: results from the Eastern Cooperative Oncology Group. Cancer Chemother Pharmacol (2011) 0.81
Expression of the copper transporters hCtr1, ATP7A and ATP7B is associated with the response to chemotherapy and survival time in patients with resected non-small cell lung cancer. Oncol Lett (2015) 0.79
ATP7B expression is associated with in vitro sensitivity to cisplatin in non-small cell lung cancer. Oncol Lett (2010) 0.79
The association between copper transporters and the prognosis of cancer patients undergoing chemotherapy: a meta-analysis of literatures and datasets. Oncotarget (2016) 0.75
ATP7B expression confers multidrug resistance through drug sequestration. Oncotarget (2016) 0.75
Expression of ATP7B in human gastric cardiac carcinomas in comparison with distal gastric carcinomas. World J Gastroenterol (2006) 0.75
A Role for The ATP7A Copper Transporter in Tumorigenesis and Cisplatin Resistance. J Cancer (2017) 0.75
BRAF mutations in papillary carcinomas of the thyroid. Oncogene (2003) 2.94
Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas. Cancer Res (2011) 2.81
Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence. Cancer Res (2008) 2.45
Clinicopathologic and biological analysis of PIK3CA mutation in ovarian clear cell carcinoma. Hum Pathol (2012) 2.27
Thymidine phosphorylase gene mutation is not a primary cause of mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). Intern Med (2006) 2.09
Impact of exacerbations on emphysema progression in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2011) 2.03
Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4. Virology (2005) 2.03
Mutations in the SLC34A2 gene are associated with pulmonary alveolar microlithiasis. Am J Respir Crit Care Med (2006) 1.98
Changes in microRNA expression levels correlate with clinicopathological features and prognoses in endometrial serous adenocarcinomas. Cancer Sci (2009) 1.85
A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip. Nucleic Acids Res (2010) 1.83
Evaluation of acoustic radiation force impulse elastography for fibrosis staging of chronic liver disease: a pilot study. Liver Int (2009) 1.82
Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients. Hum Mol Genet (2007) 1.79
Multicenter phase II study of fertility-sparing treatment with medroxyprogesterone acetate for endometrial carcinoma and atypical hyperplasia in young women. J Clin Oncol (2007) 1.66
Sentinel lymph node detection in patients with endometrial cancer. Gynecol Oncol (2004) 1.64
Colon carcinoma metastasis to the thyroid gland: report of a case with a review of the literature. Tumori (2006) 1.63
Genetic significance of skewed X-chromosome inactivation in premature ovarian failure. Am J Med Genet A (2004) 1.63
Mature adipocytes, but not preadipocytes, promote the growth of breast carcinoma cells in collagen gel matrix culture through cancer-stromal cell interactions. J Pathol (2003) 1.56
RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes. J Biol Chem (2006) 1.52
Differential expression of Janus kinase 3 (JAK3), matrix metalloproteinase 13 (MMP13), heat shock protein 60 (HSP60), and mouse double minute 2 (MDM2) in human colorectal cancer progression using human cancer cDNA microarrays. Pathol Res Pract (2005) 1.51
Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc Natl Acad Sci U S A (2004) 1.50
Tumor progression through epigenetic gene silencing of O(6)-methylguanine-DNA methyltransferase in human biliary tract cancers. Ann Surg Oncol (2005) 1.47
Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer. Oncogene (2003) 1.47
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism. Adv Drug Deliv Rev (2009) 1.45
Inhibition of estrogen actions in human gynecological malignancies: new aspects of endocrine therapy for endometrial cancer and ovarian cancer. Mol Cell Endocrinol (2010) 1.45
Biological evaluation of paclitaxel-peptide conjugates as a model for MMP2-targeted drug delivery. Cancer Biol Ther (2010) 1.45
Outcomes of fertility-sparing surgery for stage I epithelial ovarian cancer: a proposal for patient selection. J Clin Oncol (2010) 1.43
Successful conservative treatment of a cesarean scar pregnancy with uterine artery embolization. Tohoku J Exp Med (2005) 1.41
Prostaglandin E2 via steroidogenic factor-1 coordinately regulates transcription of steroidogenic genes necessary for estrogen synthesis in endometriosis. J Clin Endocrinol Metab (2008) 1.41
A novel culture system for mouse spermatid maturation which produces elongating spermatids capable of inducing calcium oscillation during fertilization and embryonic development. J Assist Reprod Genet (2010) 1.40
Re-investigation and RNA sequencing-based identification of genes with placenta-specific imprinted expression. Hum Mol Genet (2011) 1.39
Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein. J Med Chem (2012) 1.39
Loss of ARID1A expression is related to shorter progression-free survival and chemoresistance in ovarian clear cell carcinoma. Mod Pathol (2011) 1.38
DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm. Eur J Hum Genet (2009) 1.36
Integrin targeted therapeutics. Theranostics (2011) 1.36
Small molecule inhibitors of Stat3 signaling pathway. Curr Cancer Drug Targets (2007) 1.35
Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrin-targeted drug delivery. J Med Chem (2005) 1.34
Mutations and deletions of the CBP gene in human lung cancer. Clin Cancer Res (2005) 1.34
Small molecule inhibitors of CXCR4. Theranostics (2013) 1.30
Hypoxia-inducible factor 1 alpha (HIF-1 alpha) gene expression in human ovarian carcinoma. Cancer Lett (2002) 1.29
The association of microRNA expression with prognosis and progression in early-stage, non-small cell lung adenocarcinoma: a retrospective analysis of three cohorts. Clin Cancer Res (2011) 1.29
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors. Retrovirology (2009) 1.29
Relationship between pulmonary emphysema and osteoporosis assessed by CT in patients with COPD. Chest (2008) 1.28
Tumor-stromal cell interaction under hypoxia increases the invasiveness of pancreatic cancer cells through the hepatocyte growth factor/c-Met pathway. Int J Cancer (2006) 1.28
18F-FPPRGD2 and 18F-FDG PET of response to Abraxane therapy. J Nucl Med (2010) 1.28
Fast scanning tomosynthesis for the detection of pulmonary nodules: diagnostic performance compared with chest radiography, using multidetector-row computed tomography as the reference. Invest Radiol (2011) 1.26
Spontaneous fractures and quality of life in cerebral palsy. Lancet (2004) 1.26
Structural determinants for HIV-1 integrase inhibition by beta-diketo acids. J Biol Chem (2002) 1.26
Synthesis and antitumor activities of a series of novel quinoxalinhydrazides. Bioorg Med Chem (2006) 1.25
Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors. J Med Chem (2002) 1.25
Expression of twist and wnt in human breast cancer. Anticancer Res (2005) 1.23
Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate. Dev Biol (2003) 1.23
Salivary gland progenitor cells induced by duct ligation differentiate into hepatic and pancreatic lineages. Hepatology (2003) 1.22
The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading. Bone (2009) 1.20
Biological roles of estrogen and progesterone in human endometrial carcinoma--new developments in potential endocrine therapy for endometrial cancer. Endocr J (2007) 1.20
Upregulation and overexpression of human X-box binding protein 1 (hXBP-1) gene in primary breast cancers. Breast Cancer (2003) 1.19
Comparison of a variable-number tandem-repeat (VNTR) method for typing Mycobacterium avium with mycobacterial interspersed repetitive-unit-VNTR and IS1245 restriction fragment length polymorphism typing. J Clin Microbiol (2009) 1.18
Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium. Genes Chromosomes Cancer (2009) 1.18
Parvovirus B19 and the pathogenesis of anaemia. Rev Med Virol (2003) 1.18
Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment. Proc Natl Acad Sci U S A (2012) 1.18
Identification of genes whose expression is upregulated in lung adenocarcinoma cells in comparison with type II alveolar cells and bronchiolar epithelial cells in vivo. Oncogene (2004) 1.16
Discovery of a small-molecule HIV-1 integrase inhibitor-binding site. Proc Natl Acad Sci U S A (2006) 1.16
Decreased expression of 14-3-3 sigma is associated with advanced disease in human epithelial ovarian cancer: its correlation with aberrant DNA methylation. Clin Cancer Res (2004) 1.16
Synthesis and biological evaluation of novel 5(H)-phenanthridin-6-ones, 5(H)-phenanthridin-6-one diketo acid, and polycyclic aromatic diketo acid analogs as new HIV-1 integrase inhibitors. Bioorg Med Chem (2006) 1.16
Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors. Bioorg Med Chem Lett (2007) 1.16
Endometrioid uterine cancer: histopathological risk factors of local and distant recurrence. Gynecol Oncol (2008) 1.15
CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer. Oncol Rep (2009) 1.15
Role of endocrine and paracrine factors in the adaptation of bone to mechanical loading. Curr Osteoporos Rep (2011) 1.13
Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors. Molecules (2008) 1.13
Comparison of multivisceral resection and standard operation for locally advanced colorectal cancer: analysis of prognostic factors for short-term and long-term outcome. Dis Colon Rectum (2004) 1.12
Clinical experience with combination paclitaxel and carboplatin therapy for advanced or recurrent carcinosarcoma of the uterus. Gynecol Oncol (2004) 1.12
Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes. Antiviral Res (2009) 1.12
Discovery of 3-acetyl-4-hydroxy-2-pyranone derivatives and their difluoridoborate complexes as a novel class of HIV-1 integrase inhibitors. Bioorg Med Chem (2008) 1.12
Estrogen receptor α mediates proliferation of osteoblastic cells stimulated by estrogen and mechanical strain, but their acute down-regulation of the Wnt antagonist Sost is mediated by estrogen receptor β. J Biol Chem (2013) 1.11
Substituted 2-pyrrolinone inhibitors of HIV-1 integrase. Bioorg Med Chem Lett (2007) 1.11
Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors. Bioorg Med Chem Lett (2008) 1.10
Circulating myeloid-derived suppressor cells are increased and correlate to immune suppression, inflammation and hypoproteinemia in patients with cancer. Oncol Rep (2012) 1.10
Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity. J Med Chem (2012) 1.10
Mining the NCI antiviral compounds for HIV-1 integrase inhibitors. Bioorg Med Chem (2006) 1.10
Decrease and senescence of endothelial progenitor cells in patients with preeclampsia. J Clin Endocrinol Metab (2005) 1.10
Rational design and synthesis of novel dimeric diketoacid-containing inhibitors of HIV-1 integrase: implication for binding to two metal ions on the active site of integrase. J Med Chem (2004) 1.10
Reviewing the current classification of inhibitor of growth family proteins. Cancer Sci (2009) 1.09
Evidence-based guidelines for treatment of cervical cancer in Japan: Japan Society of Gynecologic Oncology (JSGO) 2007 edition. Int J Clin Oncol (2010) 1.09
Copper-transporting P-type adenosine triphosphatase (ATP7B) as a cisplatin based chemoresistance marker in ovarian carcinoma: comparative analysis with expression of MDR1, MRP1, MRP2, LRP and BCRP. Int J Cancer (2002) 1.09
Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents. J Med Chem (2006) 1.09
Treatment for the decline of ionized calcium levels during peripheral blood progenitor cell harvesting. Transfusion (2002) 1.09
E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer. Int J Cancer (2002) 1.09
The Critical Impact of HIF-1a on Gastric Cancer Biology. Cancers (Basel) (2013) 1.08
The Tohoku Medical Megabank Project: Design and Mission. J Epidemiol (2016) 1.08