| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity.
|
J Biol Chem
|
2005
|
3.51
|
|
2
|
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity.
|
Cell Metab
|
2010
|
3.11
|
|
3
|
Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages.
|
Cell Metab
|
2010
|
2.95
|
|
4
|
Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity.
|
Hepatology
|
2010
|
2.53
|
|
5
|
Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome.
|
Nat Med
|
2010
|
2.32
|
|
6
|
The G0/G1 switch gene 2 is a novel PPAR target gene.
|
Biochem J
|
2005
|
2.29
|
|
7
|
The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment.
|
J Biol Chem
|
2004
|
2.23
|
|
8
|
Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors.
|
Cancer Cell
|
2011
|
2.23
|
|
9
|
Nutrigenomics: goals and strategies.
|
Nat Rev Genet
|
2003
|
2.19
|
|
10
|
Peroxisome proliferator-activated receptor alpha target genes.
|
PPAR Res
|
2010
|
2.09
|
|
11
|
Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression.
|
Endocrinology
|
2005
|
1.90
|
|
12
|
Comprehensive analysis of PPARalpha-dependent regulation of hepatic lipid metabolism by expression profiling.
|
PPAR Res
|
2007
|
1.88
|
|
13
|
Peroxisome proliferator-activated receptor gamma activation promotes infiltration of alternatively activated macrophages into adipose tissue.
|
J Biol Chem
|
2008
|
1.81
|
|
14
|
PPARalpha governs glycerol metabolism.
|
J Clin Invest
|
2004
|
1.79
|
|
15
|
Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human.
|
PLoS One
|
2009
|
1.59
|
|
16
|
Angptl4 upregulates cholesterol synthesis in liver via inhibition of LPL- and HL-dependent hepatic cholesterol uptake.
|
Arterioscler Thromb Vasc Biol
|
2007
|
1.56
|
|
17
|
Peroxisome proliferator-activated receptor alpha protects against obesity-induced hepatic inflammation.
|
Endocrinology
|
2007
|
1.54
|
|
18
|
In vivo activation of PPAR target genes by RXR homodimers.
|
EMBO J
|
2004
|
1.53
|
|
19
|
Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity.
|
J Biol Chem
|
2012
|
1.53
|
|
20
|
Deletion of the gene encoding G0/G 1 switch protein 2 (G0s2) alleviates high-fat-diet-induced weight gain and insulin resistance, and promotes browning of white adipose tissue in mice.
|
Diabetologia
|
2014
|
1.49
|
|
21
|
Genome-wide analysis of PPARalpha activation in murine small intestine.
|
Physiol Genomics
|
2007
|
1.45
|
|
22
|
Mechanisms of inflammatory responses in obese adipose tissue.
|
Annu Rev Nutr
|
2012
|
1.45
|
|
23
|
Adipose tissue dysfunction signals progression of hepatic steatosis towards nonalcoholic steatohepatitis in C57BL/6 mice.
|
Diabetes
|
2010
|
1.43
|
|
24
|
PPARs, Obesity, and Inflammation.
|
PPAR Res
|
2007
|
1.42
|
|
25
|
Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver.
|
Mol Cell Biol
|
2009
|
1.41
|
|
26
|
Natural killer T cells in adipose tissue prevent insulin resistance.
|
J Clin Invest
|
2012
|
1.34
|
|
27
|
Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis.
|
Nucleic Acids Res
|
2010
|
1.34
|
|
28
|
ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters.
|
Blood
|
2011
|
1.33
|
|
29
|
G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase.
|
J Lipid Res
|
2012
|
1.32
|
|
30
|
Regulation of triglyceride metabolism by Angiopoietin-like proteins.
|
Biochim Biophys Acta
|
2011
|
1.32
|
|
31
|
Angiopoietin-like 4: a decade of research.
|
Biosci Rep
|
2012
|
1.31
|
|
32
|
The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria.
|
Histochem Cell Biol
|
2011
|
1.25
|
|
33
|
Modulation of plasma TG lipolysis by Angiopoietin-like proteins and GPIHBP1.
|
Biochim Biophys Acta
|
2010
|
1.19
|
|
34
|
Angiopoietin-like 4 interacts with matrix proteins to modulate wound healing.
|
J Biol Chem
|
2010
|
1.19
|
|
35
|
Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress.
|
Circ Res
|
2010
|
1.18
|
|
36
|
PPARalpha and dyslipidemia.
|
Biochim Biophys Acta
|
2007
|
1.18
|
|
37
|
Transcriptional profiling reveals divergent roles of PPARalpha and PPARbeta/delta in regulation of gene expression in mouse liver.
|
Physiol Genomics
|
2009
|
1.16
|
|
38
|
The glucocorticoid receptor controls hepatic dyslipidemia through Hes1.
|
Cell Metab
|
2008
|
1.15
|
|
39
|
Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics.
|
PLoS One
|
2008
|
1.15
|
|
40
|
Angiopoietin-like 4 interacts with integrins beta1 and beta5 to modulate keratinocyte migration.
|
Am J Pathol
|
2010
|
1.13
|
|
41
|
Mechanisms of gene regulation by fatty acids.
|
Adv Nutr
|
2012
|
1.11
|
|
42
|
Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels.
|
Diabetes
|
2012
|
1.11
|
|
43
|
Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity.
|
Prog Lipid Res
|
2011
|
1.09
|
|
44
|
Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain.
|
Endocrinology
|
2006
|
1.08
|
|
45
|
Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival.
|
Proc Natl Acad Sci U S A
|
2014
|
1.06
|
|
46
|
Pronounced effects of acute endurance exercise on gene expression in resting and exercising human skeletal muscle.
|
PLoS One
|
2012
|
1.02
|
|
47
|
Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ.
|
Mol Cell Biol
|
2013
|
0.99
|
|
48
|
Identification of human exercise-induced myokines using secretome analysis.
|
Physiol Genomics
|
2014
|
0.98
|
|
49
|
Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance.
|
Curr Opin Investig Drugs
|
2004
|
0.98
|
|
50
|
The Interleukin-1 receptor antagonist is a direct target gene of PPARalpha in liver.
|
J Hepatol
|
2006
|
0.97
|
|
51
|
Fight fat with DGAT.
|
J Lipid Res
|
2011
|
0.97
|
|
52
|
Exploration of PPAR functions by microarray technology--a paradigm for nutrigenomics.
|
Biochim Biophys Acta
|
2007
|
0.96
|
|
53
|
Energy-sensing factors coactivator peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) and AMP-activated protein kinase control expression of inflammatory mediators in liver: induction of interleukin 1 receptor antagonist.
|
J Biol Chem
|
2011
|
0.96
|
|
54
|
The ATP-P2X7 signaling axis is dispensable for obesity-associated inflammasome activation in adipose tissue.
|
Diabetes
|
2012
|
0.95
|
|
55
|
Design guidelines for the development of digital nutrigenomics learning material for heterogeneous target groups.
|
Adv Physiol Educ
|
2007
|
0.94
|
|
56
|
PPARalpha-dependent induction of the energy homeostasis-regulating nuclear receptor NR1i3 (CAR) in rat hepatocytes: potential role in starvation adaptation.
|
FEBS Lett
|
2007
|
0.94
|
|
57
|
Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue.
|
BMC Physiol
|
2012
|
0.93
|
|
58
|
Dietary modulation of plasma angiopoietin-like protein 4 concentrations in healthy volunteers and in patients with type 2 diabetes.
|
Am J Clin Nutr
|
2013
|
0.92
|
|
59
|
Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81).
|
J Biol Chem
|
2009
|
0.92
|
|
60
|
Sulfonylureas and glinides exhibit peroxisome proliferator-activated receptor gamma activity: a combined virtual screening and biological assay approach.
|
Mol Pharmacol
|
2006
|
0.89
|
|
61
|
Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise.
|
Proc Natl Acad Sci U S A
|
2014
|
0.88
|
|
62
|
Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart.
|
Physiol Genomics
|
2012
|
0.88
|
|
63
|
Regulation of lipid metabolism by angiopoietin-like proteins.
|
Curr Opin Lipidol
|
2016
|
0.87
|
|
64
|
Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion.
|
J Lipid Res
|
2012
|
0.87
|
|
65
|
Overexpression of angiopoietin-like protein 4 protects against atherosclerosis development.
|
Arterioscler Thromb Vasc Biol
|
2013
|
0.87
|
|
66
|
Analysis of the heat shock response in mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha).
|
BMC Genomics
|
2010
|
0.86
|
|
67
|
Comparative transcriptomic and metabolomic analysis of fenofibrate and fish oil treatments in mice.
|
Physiol Genomics
|
2011
|
0.85
|
|
68
|
The effects of long- or medium-chain fat diets on glucose tolerance and myocellular content of lipid intermediates in rats.
|
Obesity (Silver Spring)
|
2010
|
0.83
|
|
69
|
Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity.
|
Biochim Biophys Acta
|
2014
|
0.83
|
|
70
|
Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase.
|
Biochim Biophys Acta
|
2012
|
0.83
|
|
71
|
ANGPTL4 is produced by entero-endocrine cells in the human intestinal tract.
|
Histochem Cell Biol
|
2013
|
0.83
|
|
72
|
Perilipin 5 mediated lipid droplet remodelling revealed by coherent Raman imaging.
|
Integr Biol (Camb)
|
2015
|
0.81
|
|
73
|
Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.
|
J Biol Chem
|
2005
|
0.81
|
|
74
|
A role for the peroxisomal 3-ketoacyl-CoA thiolase B enzyme in the control of PPARα-mediated upregulation of SREBP-2 target genes in the liver.
|
Biochimie
|
2011
|
0.79
|
|
75
|
Adipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis.
|
Diabetes
|
2013
|
0.79
|
|
76
|
Omega-3 long-chain fatty acids strongly induce angiopoietin-like 4 in humans.
|
J Lipid Res
|
2013
|
0.79
|
|
77
|
Retracted
Peroxisome proliferator-activated receptor alpha controls hepatic heme biosynthesis through ALAS1.
|
J Mol Biol
|
2009
|
0.79
|
|
78
|
Plasma mannose-binding lectin is stimulated by PPARα in humans.
|
Am J Physiol Endocrinol Metab
|
2012
|
0.79
|
|
79
|
Molecular mechanisms underlying the potential antiobesity-related diseases effect of cocoa polyphenols.
|
Mol Nutr Food Res
|
2013
|
0.78
|
|
80
|
Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury.
|
Am J Physiol Renal Physiol
|
2012
|
0.77
|
|
81
|
PPARδ activation in human myotubes increases mitochondrial fatty acid oxidative capacity and reduces glucose utilization by a switch in substrate preference.
|
Arch Physiol Biochem
|
2013
|
0.77
|
|
82
|
Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology.
|
BMC Genomics
|
2014
|
0.76
|
|
83
|
Bioactivity screening and mass spectrometric confirmation for the detection of PPARδ agonists that increase type 1 muscle fibres.
|
Anal Bioanal Chem
|
2013
|
0.76
|
|
84
|
Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance.
|
Nat Commun
|
2015
|
0.75
|
|
85
|
Saturated fatty acids and snoRNAs: partners in crime.
|
Cell Metab
|
2011
|
0.75
|
|
86
|
The PPARgamma ligand rosiglitazone influences triacylglycerol metabolism in non-obese males, without increasing the transcriptional activity of PPARgamma in the subcutaneous adipose tissue.
|
Br J Nutr
|
2008
|
0.75
|
|
87
|
PPARS and Obesity.
|
PPAR Res
|
2007
|
0.75
|