|
1
|
Isothermal titration calorimetry: general formalism using binding polynomials.
|
Methods Enzymol
|
2009
|
1.29
|
|
2
|
Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria.
|
J Clin Invest
|
2008
|
1.26
|
|
3
|
Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro.
|
Biochemistry
|
2004
|
1.20
|
|
4
|
A structural and thermodynamic escape mechanism from a drug resistant mutation of the HIV-1 protease.
|
Proteins
|
2004
|
1.02
|
|
5
|
Structural basis for the interaction of unstructured neuron specific substrates neuromodulin and neurogranin with Calmodulin.
|
Sci Rep
|
2013
|
0.98
|
|
6
|
Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets.
|
Int J Biochem Cell Biol
|
2004
|
0.95
|
|
7
|
Structural analysis of the regulation of the DYNLL/LC8 binding to Nek9 by phosphorylation.
|
J Biol Chem
|
2013
|
0.91
|
|
8
|
Structural characterization of myotoxic ecarpholin S from Echis carinatus venom.
|
Biophys J
|
2008
|
0.90
|
|
9
|
Structure of GrlR-GrlA complex that prevents GrlA activation of virulence genes.
|
Nat Commun
|
2013
|
0.87
|
|
10
|
Plant tumour biocontrol agent employs a tRNA-dependent mechanism to inhibit leucyl-tRNA synthetase.
|
Nat Commun
|
2013
|
0.85
|
|
11
|
Conformational stability of hepatitis C virus NS3 protease.
|
Biophys J
|
2010
|
0.84
|
|
12
|
Thermodynamics of protein-cation interaction: Ca(+2) and Mg(+2) binding to the fifth binding module of the LDL receptor.
|
Proteins
|
2010
|
0.84
|
|
13
|
Thermodynamics of zinc binding to hepatitis C virus NS3 protease: a folding by binding event.
|
Proteins
|
2009
|
0.84
|
|
14
|
Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase.
|
Mol Pharm
|
2011
|
0.83
|
|
15
|
Contribution of disulfide bonds to stability, folding, and amyloid fibril formation: the PI3-SH3 domain case.
|
Antioxid Redox Signal
|
2011
|
0.83
|
|
16
|
Allosteric inhibitors of the NS3 protease from the hepatitis C virus.
|
PLoS One
|
2013
|
0.81
|
|
17
|
Studying the allosteric energy cycle by isothermal titration calorimetry.
|
Methods Mol Biol
|
2012
|
0.81
|
|
18
|
Identification and characterization of the lipid-binding property of GrlR, a locus of enterocyte effacement regulator.
|
Biochem J
|
2009
|
0.80
|
|
19
|
NS3 protease from hepatitis C virus: biophysical studies on an intrinsically disordered protein domain.
|
Int J Mol Sci
|
2013
|
0.78
|
|
20
|
Extending in silico mechanism-of-action analysis by annotating targets with pathways: application to cellular cytotoxicity readouts.
|
Future Med Chem
|
2014
|
0.77
|
|
21
|
Structural basis for dual-inhibition mechanism of a non-classical Kazal-type serine protease inhibitor from horseshoe crab in complex with subtilisin.
|
PLoS One
|
2011
|
0.77
|
|
22
|
Partition of amphiphilic molecules to lipid bilayers by isothermal titration calorimetry.
|
Anal Biochem
|
2009
|
0.75
|
|
23
|
Synthesis and characterization of a lipidic alpha amino acid: solubility and interaction with serum albumin and lipid bilayers.
|
J Phys Chem B
|
2013
|
0.75
|
|
24
|
Kinetics and thermodynamics of chlorpromazine interaction with lipid bilayers: effect of charge and cholesterol.
|
J Am Chem Soc
|
2012
|
0.75
|