| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Linearized reference tissue parametric imaging methods: application to [11C]DASB positron emission tomography studies of the serotonin transporter in human brain.
|
J Cereb Blood Flow Metab
|
2003
|
3.77
|
|
2
|
Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography.
|
J Neurosci
|
2007
|
1.85
|
|
3
|
Decreased dopamine D2 receptor binding in the anterior cingulate cortex in schizophrenia.
|
Arch Gen Psychiatry
|
2002
|
1.75
|
|
4
|
Inhibitory effect of hippocampal 5-HT1A receptors on human explicit memory.
|
Am J Psychiatry
|
2003
|
1.53
|
|
5
|
Quantitative analyses of 18F-FEDAA1106 binding to peripheral benzodiazepine receptors in living human brain.
|
J Nucl Med
|
2006
|
1.36
|
|
6
|
Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies.
|
J Neurosci
|
2008
|
1.29
|
|
7
|
Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor.
|
Brain Res
|
2007
|
1.24
|
|
8
|
Remote control production of an aqueous solution of no-carrier-added 34mCl- via the 32S(alpha,pn) nuclear reaction.
|
Appl Radiat Isot
|
2007
|
1.21
|
|
9
|
Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [(11)C]DAA1106.
|
J Cereb Blood Flow Metab
|
2006
|
1.20
|
|
10
|
Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain.
|
Synapse
|
2004
|
1.20
|
|
11
|
In vivo evaluation of P-glycoprotein function at the blood-brain barrier in nonhuman primates using [11C]verapamil.
|
J Pharmacol Exp Ther
|
2005
|
1.19
|
|
12
|
Evaluation of in vivo P-glycoprotein function at the blood-brain barrier among MDR1 gene polymorphisms by using 11C-verapamil.
|
J Nucl Med
|
2006
|
1.15
|
|
13
|
[(11)C]DAA1106: radiosynthesis and in vivo binding to peripheral benzodiazepine receptors in mouse brain.
|
Nucl Med Biol
|
2003
|
1.12
|
|
14
|
Quantitative analysis of 11C-verapamil transfer at the human blood-brain barrier for evaluation of P-glycoprotein function.
|
J Nucl Med
|
2006
|
1.12
|
|
15
|
Development of a new radioligand, N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoroethyl-5-methoxybenzyl)acetamide, for pet imaging of peripheral benzodiazepine receptor in primate brain.
|
J Med Chem
|
2004
|
1.10
|
|
16
|
How to introduce radioactive chlorine into a benzene ring using [*Cl]Cl-?
|
Appl Radiat Isot
|
2008
|
1.09
|
|
17
|
A dose-finding study of duloxetine based on serotonin transporter occupancy.
|
Psychopharmacology (Berl)
|
2006
|
1.00
|
|
18
|
Extrastriatal dopamine D2 receptor density and affinity in the human brain measured by 3D PET.
|
Int J Neuropsychopharmacol
|
1999
|
0.98
|
|
19
|
11C-AC-5216: a novel PET ligand for peripheral benzodiazepine receptors in the primate brain.
|
J Nucl Med
|
2007
|
0.95
|
|
20
|
Feasibility studies of 4'-[methyl-(11)C]thiothymidine as a tumor proliferation imaging agent in mice.
|
Nucl Med Biol
|
2008
|
0.92
|
|
21
|
In vivo evaluation of P-glycoprotein and breast cancer resistance protein modulation in the brain using [(11)C]gefitinib.
|
Nucl Med Biol
|
2009
|
0.91
|
|
22
|
[(11)C]methionine positron emission tomography and survival in patients with bone and soft tissue sarcomas treated by carbon ion radiotherapy.
|
Clin Cancer Res
|
2004
|
0.89
|
|
23
|
Evaluation of 4'-[methyl-14C]thiothymidine for in vivo DNA synthesis imaging.
|
J Nucl Med
|
2006
|
0.88
|
|
24
|
Neuroimaging and physiological evidence for involvement of glutamatergic transmission in regulation of the striatal dopaminergic system.
|
J Neurosci
|
2009
|
0.87
|
|
25
|
[18F]Fluoroalkyl agents: synthesis, reactivity and application for development of PET ligands in molecular imaging.
|
Curr Top Med Chem
|
2007
|
0.87
|
|
26
|
11C-methionine-PET for evaluation of carbon ion radiotherapy in patients with pelvic recurrence of rectal cancer.
|
Mol Imaging Biol
|
2008
|
0.86
|
|
27
|
[11C]Gefitinib ([11c]Iressa): radiosynthesis, in vitro uptake, and in vivo imaging of intact murine fibrosarcoma.
|
Mol Imaging Biol
|
2009
|
0.86
|
|
28
|
Visualization of early infarction in rat brain after ischemia using a translocator protein (18 kDa) PET ligand [11C]DAC with ultra-high specific activity.
|
Neuroimage
|
2010
|
0.86
|
|
29
|
Quantitative analysis of norepinephrine transporter in the human brain using PET with (S,S)-18F-FMeNER-D2.
|
J Nucl Med
|
2008
|
0.85
|
|
30
|
An analysis of long-distance water transport in the soybean stem using H215O.
|
Plant Cell Physiol
|
2008
|
0.85
|
|
31
|
A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR) system.
|
Neurochem Int
|
2008
|
0.85
|
|
32
|
The antipsychotic sultopride is overdosed--a PET study of drug-induced receptor occupancy in comparison with sulpiride.
|
Int J Neuropsychopharmacol
|
2005
|
0.84
|
|
33
|
Microdialysis with radiometric monitoring of L-[β-11C]DOPA to assess dopaminergic metabolism: effect of inhibitors of L-amino acid decarboxylase, monoamine oxidase, and catechol-O-methyltransferase on rat striatal dialysate.
|
J Cereb Blood Flow Metab
|
2010
|
0.84
|
|
34
|
[18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR).
|
Bioorg Med Chem Lett
|
2003
|
0.83
|
|
35
|
Comparison of conventional and novel PET tracers for imaging mesothelioma in nude mice with subcutaneous and intrapleural xenografts.
|
Nucl Med Biol
|
2009
|
0.83
|
|
36
|
Development of an automated system for synthesizing 18F-labeled compounds using [18F]fluoroethyl bromide as a synthetic precursor.
|
Appl Radiat Isot
|
2002
|
0.83
|
|
37
|
Synthesis and evaluation of N-(5-fluoro-2-phenoxyphenyl)-N-(2-[(18)F]fluoromethoxy-d(2)-5-methoxybenzyl)acetamide: a deuterium-substituted radioligand for peripheral benzodiazepine receptor.
|
Bioorg Med Chem
|
2005
|
0.82
|
|
38
|
Simultaneous analysis of FDG, ClDG and Kryptofix 2.2.2 in [18F]FDG preparation by high-performance liquid chromatography with UV detection.
|
Nucl Med Biol
|
2008
|
0.82
|
|
39
|
Quantitative analysis of dopamine synthesis in human brain using positron emission tomography with L-[beta-11C]DOPA.
|
Nucl Med Commun
|
2006
|
0.81
|
|
40
|
Evaluation of N-benzyl-N-[11C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat.
|
Synapse
|
2009
|
0.81
|
|
41
|
Effects of anesthesia upon 18F-FDG uptake in rhesus monkey brains.
|
Ann Nucl Med
|
2005
|
0.81
|
|
42
|
Visualization of alpha5 subunit of GABAA/benzodiazepine receptor by 11C Ro15-4513 using positron emission tomography.
|
Synapse
|
2003
|
0.81
|
|
43
|
Evaluation of chemotherapy response in VX2 rabbit lung cancer with 18F-labeled C2A domain of synaptotagmin I.
|
J Nucl Med
|
2011
|
0.81
|
|
44
|
Carbon-11-methionine positron emission tomography imaging of chordoma.
|
Skeletal Radiol
|
2004
|
0.80
|
|
45
|
Quantitative PET analysis of the dopamine D2 receptor agonist radioligand 11C-(R)-2-CH3O-N-n-propylnorapomorphine in the human brain.
|
J Nucl Med
|
2009
|
0.80
|
|
46
|
Time course of in vivo 5-HTT transporter occupancy by fluvoxamine.
|
J Clin Psychopharmacol
|
2006
|
0.80
|
|
47
|
Quantitative analysis of dopamine transporters in human brain using [11C]PE2I and positron emission tomography: evaluation of reference tissue models.
|
Ann Nucl Med
|
2010
|
0.80
|
|
48
|
In vivo mapping of substance P receptors in brains of laboratory animals by high-resolution imaging systems.
|
Synapse
|
2007
|
0.80
|
|
49
|
[18F]FEAC and [18F]FEDAC: Two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in the brain.
|
Bioorg Med Chem Lett
|
2009
|
0.80
|
|
50
|
High-yield automated synthesis of [18F]fluoroazomycin arabinoside ([18F]FAZA) for hypoxia-specific tumor imaging.
|
Appl Radiat Isot
|
2011
|
0.79
|
|
51
|
Carbon-11-methionine PET imaging of choroidal melanoma and the time course after carbon ion beam radiotherapy.
|
Anticancer Res
|
2009
|
0.79
|
|
52
|
In vitro and ex vivo autoradiography studies on peripheral-type benzodiazepine receptor binding using [11C]AC-5216 in normal and kainic acid-lesioned rats.
|
Neurosci Lett
|
2007
|
0.79
|
|
53
|
Cation exchange separation of 61Cu2+ from natCo targets and preparation of 61Cu-DOTA-HSA as a blood pool agent.
|
Appl Radiat Isot
|
2008
|
0.79
|
|
54
|
N-(5-Fluoro-2-phenoxyphenyl)-N-(2-[(131)I]iodo-5-me thoxybenzyl)acetamide: a potent iodinated radioligand for the peripheral-type benzodiazepine receptor in brain.
|
J Med Chem
|
2007
|
0.79
|
|
55
|
In vivo monitoring of extracellular 13N-glutamine derived from blood-borne 13N-ammonia in rat striatum using microdialysis with radio-LC method.
|
J Neurosci Methods
|
2009
|
0.78
|
|
56
|
Quantitative analysis of NK1 receptor in the human brain using PET with 18F-FE-SPA-RQ.
|
J Nucl Med
|
2008
|
0.78
|
|
57
|
Selective synthesis of [2-(11)C]2-iodopropane and [1-(11)C]iodoethane using the loop method by reacting methylmagnesium bromide with [11C]carbon dioxide.
|
Appl Radiat Isot
|
2005
|
0.78
|
|
58
|
In vitro binding of [(11)C]raclopride with ultrahigh specific activity in rat brain determined by homogenate assay and autoradiography.
|
Nucl Med Biol
|
2008
|
0.78
|
|
59
|
[2-11C]isopropyl-, [1-11C]ethyl-, and [11C]methyl-labeled phenoxyphenyl acetamide derivatives as positron emission tomography ligands for the peripheral benzodiazepine receptor: radiosynthesis, uptake, and in vivo binding in brain.
|
J Med Chem
|
2006
|
0.78
|
|
60
|
Biodistribution and metabolism of the anti-influenza drug [11C]oseltamivir and its active metabolite [11C]Ro 64-0802 in mice.
|
Nucl Med Biol
|
2009
|
0.78
|
|
61
|
Measurement of dopamine D2 receptors in living human brain using [11C]raclopride with ultra-high specific radioactivity.
|
Nucl Med Biol
|
2010
|
0.78
|
|
62
|
Imaging of the translocator protein (18 kDa) in rat brain after ischemia using [11C]DAC with ultra-high specific activity.
|
Synapse
|
2010
|
0.77
|
|
63
|
Synthesis and evaluation of 3-(4-chlorobenzyl)-8-[11C]methoxy-1,2,3,4-tetrahydrochromeno[3,4-c]pyridin-5-one: a PET tracer for imaging sigma(1) receptors.
|
Nucl Med Biol
|
2002
|
0.77
|
|
64
|
Effects of endogenous agonists, glycine and D-serine, on in vivo specific binding of [11C]L-703,717, a PET radioligand for the glycine-binding site of NMDA receptors.
|
Synapse
|
2003
|
0.77
|
|
65
|
N-[18F]fluoroethylpiperidin-4-ylmethyl butyrate: a novel radiotracer for quantifying brain butyrylcholinesterase activity by positron emission tomography.
|
Bioorg Med Chem Lett
|
2004
|
0.77
|
|
66
|
Effects of smoking on the lung accumulation of [11C]McN5652.
|
Ann Nucl Med
|
2007
|
0.77
|
|
67
|
In vivo drug action of tandospirone at 5-HT1A receptor examined using positron emission tomography and neuroendocrine response.
|
Psychopharmacology (Berl)
|
2002
|
0.77
|
|
68
|
An improved 62Zn/62Cu generator based on a cation exchanger and its fully remote-controlled preparation for clinical use.
|
Nucl Med Biol
|
2006
|
0.77
|
|
69
|
Utility of small-animal positron emission tomographic imaging of rats for preclinical development of drugs acting on the serotonin transporter.
|
Int J Neuropsychopharmacol
|
2009
|
0.77
|
|
70
|
Efficient and reproducible synthesis of [1-11C]acetyl chloride using the loop method.
|
Appl Radiat Isot
|
2008
|
0.77
|
|
71
|
Quantitative analysis for estimating binding potential of the brain serotonin transporter with [11 C]McN5652.
|
J Cereb Blood Flow Metab
|
2002
|
0.76
|
|
72
|
Development of N-[11C]methylamino 4-hydroxy-2(1H)-quinolone derivatives as PET radioligands for the glycine-binding site of NMDA receptors.
|
Bioorg Med Chem
|
2009
|
0.76
|
|
73
|
Measurement of glycine binding site of N-methyl-D-asparate receptors in living human brain using 4-acetoxy derivative of L-703,717, 4-acetoxy-7-chloro-3-[3-(4-[11c] methoxybenzyl) phenyl]-2(1H)-quinolone (AcL703) with positron emission tomography.
|
Synapse
|
2007
|
0.76
|
|
74
|
Radiosynthesis of [13N]dantrolene, a positron emission tomography probe for breast cancer resistant protein, using no-carrier-added [13N]ammonia.
|
Bioorg Med Chem
|
2011
|
0.76
|
|
75
|
N-[18F] fluoroethylpiperidin-4ylmethyl acetate, a novel lipophilic acetylcholine analogue for PET measurement of brain acetylcholinesterase activity.
|
J Med Chem
|
2005
|
0.76
|
|
76
|
Syntheses and pharmacological evaluation of two potent antagonists for dopamine D4 receptors: [11C]YM-50001 and N-[2-[4-(4-Chlorophenyl)-piperizin-1-yl]ethyl]-3-[11C]methoxybenzamide.
|
Nucl Med Biol
|
2002
|
0.76
|
|
77
|
Difference in brain distributions of carbon 11-labeled 4-hydroxy-2(1H)-quinolones as PET radioligands for the glycine-binding site of the NMDA ion channel.
|
Nucl Med Biol
|
2008
|
0.76
|
|
78
|
Combining high-performance liquid chromatography-positron detection and on-line microdialysis for animal metabolism study of positron emission tomography probes.
|
J Chromatogr A
|
2008
|
0.76
|
|
79
|
Imaging of peripheral-type benzodiazepine receptor in tumor: in vitro binding and in vivo biodistribution of N-benzyl-N-[(11)C]methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide.
|
Nucl Med Biol
|
2009
|
0.76
|
|
80
|
Synthesis, in vitro and in vivo pharmacology of a C-11 labeled analog of CP-101,606, (+/-)threo-1-(4-hydroxyphenyl)-2-[4-hydroxy-4-(p-[11C]methoxyphenyl)piperidino]-1-propanol, as a PET tracer for NR2B subunit-containing NMDA receptors.
|
Nucl Med Biol
|
2002
|
0.75
|
|
81
|
Sources of carbon which decrease the specific activity of [11C]CH3I synthesized by the single pass I2 method.
|
Appl Radiat Isot
|
2005
|
0.75
|
|
82
|
Synthesis and biodistribution of 34mCl-labeled 2-chloro-2-deoxy-d-glucose: a major impurity in [18F]FDG injection.
|
Appl Radiat Isot
|
2008
|
0.75
|
|
83
|
Rapid C-carboxylation of nitro[(11)C]methane for the synthesis of ethyl nitro[2-(11)C]acetate.
|
Mol Biosyst
|
2007
|
0.75
|
|
84
|
Rapid and efficient purification of positron emission tomography probes by hydrophilic interaction chromatography.
|
J Chromatogr A
|
2009
|
0.75
|
|
85
|
Binding kinetics of 11C-N-methyl piperidyl benzilate (11C-NMPB) in a rhesus monkey brain using the cerebellum as a reference region.
|
Ann Nucl Med
|
2005
|
0.75
|
|
86
|
1-Minute quality control tests for positron emission tomography radiopharmaceuticals.
|
J Pharm Biomed Anal
|
2009
|
0.75
|
|
87
|
Comparative evaluation of two serotonin transporter ligands in the human brain: [(11)C](+)McN5652 and [(11)C]cyanoimipramine.
|
Eur J Nucl Med Mol Imaging
|
2002
|
0.75
|
|
88
|
Synthesis and brain regional distribution of [11C]NPS 1506 in mice and rat: an N-methyl-D-aspartate (NMDA) receptor antagonist.
|
Biol Pharm Bull
|
2003
|
0.75
|
|
89
|
Decomposition of an aqueous solution of [11C]Ro 15-4513: implication of hydrated electrons in the radiolysis of [11C]Ro 15-4513.
|
Nucl Med Biol
|
2003
|
0.75
|
|
90
|
Sensitive determination of specific radioactivity of positron emission tomography radiopharmaceuticals by radio high-performance liquid chromatography with fluorescence detection.
|
Nucl Med Biol
|
2008
|
0.75
|
|
91
|
Synthesis and preliminary evaluation of [18F]FEtP4A, a promising PET tracer for mapping acetylcholinesterase in vivo.
|
Nucl Med Biol
|
2002
|
0.75
|
|
92
|
Improved quality control of [18F]FDG by HPLC with UV detection.
|
Nucl Med Biol
|
2005
|
0.75
|
|
93
|
Ionic interaction of [11C]-N,alpha-dimethylbenzylamine (DMBA) in rodent brain.
|
Ann Nucl Med
|
2003
|
0.75
|
|
94
|
Blood flow dependence of the intratumoral distribution of peripheral benzodiazepine receptor binding in intact mouse fibrosarcoma.
|
Nucl Med Biol
|
2006
|
0.75
|
|
95
|
Synthesis of (11)C-labeled 2-aminoethanol via a nitroaldol reaction using nitro[(11)C]methane.
|
Bioorg Med Chem Lett
|
2009
|
0.75
|
|
96
|
Ultrafast LC method for purification and metabolite analysis of PET probes.
|
Nucl Med Biol
|
2009
|
0.75
|
|
97
|
Development and validation of a liquid chromatographic method for the analysis of positron emission tomography radiopharmaceuticals with Ru(bpy)(3)(2+)-KMnO(4) chemiluminescence detection.
|
Anal Sci
|
2007
|
0.75
|
|
98
|
A positron-emitter labeled glycine(B) site antagonist, [(11)C]L-703,717, preferentially binds to a cerebellar NMDA receptor subtype consisting of GluR epsilon3 subunit in vivo, but not in vitro.
|
Synapse
|
2002
|
0.75
|
|
99
|
Synthesis of (R,S)-[4-11C]baclofen via Michael addition of nitromethane labeled with short-lived 11C.
|
Bioorg Med Chem Lett
|
2009
|
0.75
|
|
100
|
N-[18F]fluoroethyl-4-piperidyl acetate ([18F]FEtP4A): A PET tracer for imaging brain acetylcholinesterase in vivo.
|
Bioorg Med Chem
|
2003
|
0.75
|
|
101
|
Synthesis of 11C-labelled bis(phenylalkyl)amines and their in vitro and in vivo binding properties in rodent and monkey brains.
|
Biol Pharm Bull
|
2004
|
0.75
|
|
102
|
Fully automated production of iodine-124 using a vertical beam.
|
Appl Radiat Isot
|
2010
|
0.75
|
|
103
|
Radiosyntheses of two positron emission tomography probes: [11C]Oseltamivir and its active metabolite [11C]Ro 64-0802.
|
Bioorg Med Chem Lett
|
2008
|
0.75
|
|
104
|
Quality control of PET radiopharmaceuticals by high-performance liquid chromatography with tris(2,2'-bipyridyl)ruthenium(II) electrogenerated chemiluminescence detection.
|
Biomed Chromatogr
|
2010
|
0.75
|
|
105
|
Quality control of PET radiopharmaceuticals using HPLC with electrochemical detection.
|
Nucl Med Biol
|
2006
|
0.75
|