Published in Curr Opin Genet Dev on February 01, 2004
Ski and SnoN, potent negative regulators of TGF-beta signaling. Cell Res (2009) 2.07
Transforming growth factor-β and the hallmarks of cancer. Cell Signal (2010) 1.66
Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation. Mol Cell Biol (2007) 1.65
Transforming growth factors beta coordinate cartilage and tendon differentiation in the developing limb mesenchyme. J Biol Chem (2009) 1.35
Hepatocyte growth factor inhibits epithelial to myofibroblast transition in lung cells via Smad7. Am J Respir Cell Mol Biol (2008) 1.30
Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover. PLoS Biol (2007) 1.24
A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene. Mol Cell Biol (2005) 1.22
Transcriptional regulation of neuronal polarity and morphogenesis in the mammalian brain. Neuron (2011) 1.19
Modulation of TGF-beta signaling by proinflammatory cytokines in articular chondrocytes. Osteoarthritis Cartilage (2007) 1.16
The dynamic ubiquitin ligase duo: Cdh1-APC and Cdc20-APC regulate neuronal morphogenesis and connectivity. Curr Opin Neurobiol (2010) 1.14
Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-beta signaling by sequestration of the Smad proteins. Proc Natl Acad Sci U S A (2005) 1.14
Multiple transcription factor families regulate axon growth and regeneration. Dev Neurobiol (2011) 1.13
Dynamics of TGF-β/Smad signaling. FEBS Lett (2012) 1.12
Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex. Mol Cell Biol (2008) 1.12
A SnoN-Ccd1 pathway promotes axonal morphogenesis in the mammalian brain. J Neurosci (2009) 1.09
Requirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells. Mol Cell Biol (2005) 1.08
ING2 as a novel mediator of transforming growth factor-beta-dependent responses in epithelial cells. J Biol Chem (2008) 1.08
TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation. J Biol Chem (2007) 1.08
Smad ubiquitination regulatory factor-2 in the fibrotic kidney: regulation, target specificity, and functional implication. Am J Physiol Renal Physiol (2008) 1.04
The transcription factor Gli3 regulates differentiation of fetal CD4- CD8- double-negative thymocytes. Blood (2005) 1.04
Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics. Mol Syst Biol (2011) 1.03
Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression. Mol Cell Biol (2008) 0.99
The Smad3 linker region contains a transcriptional activation domain. Biochem J (2005) 0.99
Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression. Am J Pathol (2010) 0.99
SnoN in mammalian development, function and diseases. Curr Opin Pharmacol (2010) 0.98
To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modifications. Cell Signal (2008) 0.97
Molecular mechanisms of thoracic aortic dissection. J Surg Res (2013) 0.96
Novel functions for the anaphase-promoting complex in neurobiology. Semin Cell Dev Biol (2011) 0.94
An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal morphogenesis and positioning in the mammalian brain. Neuron (2011) 0.93
Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression. Mol Cancer (2011) 0.92
Arkadia regulates tumor metastasis by modulation of the TGF-β pathway. Cancer Res (2013) 0.91
Expression of thrombospondin-1 and Ski are prognostic factors in advanced gastric cancer. Int J Clin Oncol (2010) 0.90
Smad ubiquitination regulatory factor 2 expression is enhanced in hypertrophic scar fibroblasts from burned children. Burns (2011) 0.90
Expression and localization of Ski determine cell type-specific TGFbeta signaling effects on the cell cycle. J Cell Biol (2008) 0.87
Ski inhibits TGF-β/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes. J Cell Biochem (2012) 0.87
Transforming growth factor-β/SMAD Target gene SKIL is negatively regulated by the transcriptional cofactor complex SNON-SMAD4. J Biol Chem (2012) 0.86
Identification of a Novel Link between the Protein Kinase NDR1 and TGFβ Signaling in Epithelial Cells. PLoS One (2013) 0.86
SnoN expression is differently regulated in microsatellite unstable compared with microsatellite stable colorectal cancers. BMC Cancer (2006) 0.86
A decade of the anaphase-promoting complex in the nervous system. Genes Dev (2016) 0.86
Intercellular variation in signaling through the TGF-β pathway and its relation to cell density and cell cycle phase. Mol Cell Proteomics (2012) 0.85
Cooperative involvement of NFAT and SnoN mediates transforming growth factor-β (TGF-β) induced EMT in metastatic breast cancer (MDA-MB 231) cells. Clin Exp Metastasis (2013) 0.84
A Comprehensive Transcriptomic and Proteomic Analysis of Hydra Head Regeneration. Mol Biol Evol (2015) 0.83
A quantitative trait locus on chromosome 4 affects cycling of hematopoietic stem and progenitor cells through regulation of TGF-beta 2 responsiveness. J Immunol (2008) 0.83
Regulation of transforming growth factor beta-induced responses by protein kinase A in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol (2008) 0.83
Phosphorylation of the anaphase-promoting complex/Cdc27 is involved in TGF-beta signaling. J Biol Chem (2011) 0.83
Differential role of Sloan-Kettering Institute (Ski) protein in Nodal and transforming growth factor-beta (TGF-β)-induced Smad signaling in prostate cancer cells. Carcinogenesis (2012) 0.83
SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling. Development (2012) 0.83
The predictive value of genes of the TGF-beta1 pathway in multimodally treated squamous cell carcinoma of the esophagus. Int J Colorectal Dis (2009) 0.82
Distinct transcriptional networks in quiescent myoblasts: a role for Wnt signaling in reversible vs. irreversible arrest. PLoS One (2013) 0.81
Oxymatrine Inhibits Renal Tubular EMT Induced by High Glucose via Upregulation of SnoN and Inhibition of TGF-β1/Smad Signaling Pathway. PLoS One (2016) 0.81
SnoN facilitates ALK1-Smad1/5 signaling during embryonic angiogenesis. J Cell Biol (2013) 0.81
SnoN in regulation of embryonic development and tissue morphogenesis. FEBS Lett (2012) 0.81
SnoN oncoprotein enhances estrogen receptor-α transcriptional activity. Cell Signal (2011) 0.80
Adiponectin attenuates lung fibroblasts activation and pulmonary fibrosis induced by paraquat. PLoS One (2015) 0.80
A two-gene signature, SKI and SLAMF1, predicts time-to-treatment in previously untreated patients with chronic lymphocytic leukemia. PLoS One (2011) 0.79
Protein kinase A modulates transforming growth factor-β signaling through a direct interaction with Smad4 protein. J Biol Chem (2013) 0.79
Association of v-ErbA with Smad4 disrupts TGF-beta signaling. Mol Biol Cell (2009) 0.76
Regulation of early xenopus embryogenesis by Smad ubiquitination regulatory factor 2. Dev Dyn (2012) 0.76
SnoN upregulation ameliorates renal fibrosis in diabetic nephropathy. PLoS One (2017) 0.75
Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39. Sci Rep (2016) 0.75
Novel regulation of Ski protein stability and endosomal sorting by actin cytoskeleton dynamics in hepatocytes. J Biol Chem (2015) 0.75
Induction of Ski Protein Expression upon Luteinization in Rat Granulosa Cells. Asian-Australas J Anim Sci (2012) 0.75
The cell survival pathways of the primordial RNA-DNA complex remain conserved in the extant genomes and may function as proto-oncogenes. Eur J Microbiol Immunol (Bp) (2015) 0.75
SnoN Antagonizes the Hippo Kinase Complex to Promote TAZ Signaling during Breast Carcinogenesis. Dev Cell (2016) 0.75
TGF-β-activated kinase-1: New insights into the mechanism of TGF-β signaling and kidney disease. Kidney Res Clin Pract (2012) 0.75