Published in Diabetes on May 01, 2004
Oxidative stress and diabetic complications. Circ Res (2010) 9.37
Mitochondrial energy metabolism in heart failure: a question of balance. J Clin Invest (2005) 2.98
Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities. Antioxid Redox Signal (2010) 2.11
As a matter of fat. Cell Metab (2009) 1.85
Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment. Heart Fail Rev (2012) 1.61
Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3. Diabetes (2008) 1.55
Molecular mechanisms of diabetic cardiomyopathy. Diabetologia (2014) 1.53
Mitochondria in the diabetic heart. Cardiovasc Res (2010) 1.50
Rac1 is required for cardiomyocyte apoptosis during hyperglycemia. Diabetes (2009) 1.38
Diabetic cardiomyopathy: bench to bedside. Heart Fail Clin (2012) 1.19
Diabetic cardiomyopathy. Clin Sci (Lond) (2009) 1.18
Mitochondrial matrix metalloproteinase activation decreases myocyte contractility in hyperhomocysteinemia. Am J Physiol Heart Circ Physiol (2008) 1.17
NRF2, cancer and calorie restriction. Oncogene (2010) 1.17
Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes. J Biol Chem (2013) 1.15
Alterations in the diabetic myocardial proteome coupled with increased myocardial oxidative stress underlies diabetic cardiomyopathy. J Mol Cell Cardiol (2007) 1.15
The non-coding RNA gadd7 is a regulator of lipid-induced oxidative and endoplasmic reticulum stress. J Biol Chem (2009) 1.13
Mitochondrial dysfunction in diabetic cardiomyopathy. Biochim Biophys Acta (2011) 1.12
Superoxide and respiratory coupling in mitochondria of insulin-deficient diabetic rats. Endocrinology (2008) 1.11
High dietary fat selectively increases catalase expression within cardiac mitochondria. J Biol Chem (2012) 1.09
Cardiac metallothionein synthesis in streptozotocin-induced diabetic mice, and its protection against diabetes-induced cardiac injury. Am J Pathol (2005) 1.06
Suppression of autophagy is protective in high glucose-induced cardiomyocyte injury. Autophagy (2012) 1.05
MMP-9 gene ablation and TIMP-4 mitigate PAR-1-mediated cardiomyocyte dysfunction: a plausible role of dicer and miRNA. Cell Biochem Biophys (2010) 1.04
Regulation of cell physiology and pathology by protein S-glutathionylation: lessons learned from the cardiovascular system. Antioxid Redox Signal (2012) 1.03
Anti-inflammatory and anti-coagulatory activities of caffeic acid and ellagic acid in cardiac tissue of diabetic mice. Nutr Metab (Lond) (2009) 1.01
Cardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapies. Curr Pharm Des (2013) 0.99
Causes and characteristics of diabetic cardiomyopathy. Rev Diabet Stud (2006) 0.99
Regulation of mitochondrial morphology and function by O-GlcNAcylation in neonatal cardiac myocytes. Am J Physiol Regul Integr Comp Physiol (2011) 0.98
Mitochondrial morphology in metabolic diseases. Antioxid Redox Signal (2012) 0.98
Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload. J Mol Cell Cardiol (2014) 0.94
Diabetic Cardiomyopathy in OVE26 Mice Shows Mitochondrial ROS Production and Divergence Between In Vivo and In Vitro Contractility. Rev Diabet Stud (2007) 0.94
Emerging role for antioxidant therapy in protection against diabetic cardiac complications: experimental and clinical evidence for utilization of classic and new antioxidants. Curr Cardiol Rev (2008) 0.93
Emerging roles of cardiolipin remodeling in mitochondrial dysfunction associated with diabetes, obesity, and cardiovascular diseases. J Biomed Res (2010) 0.93
Particulate matter exposure exacerbates high glucose-induced cardiomyocyte dysfunction through ROS generation. PLoS One (2011) 0.92
Molecular role of GATA binding protein 4 (GATA-4) in hyperglycemia-induced reduction of cardiac contractility. Cardiovasc Diabetol (2011) 0.92
Azelnidipine protects myocardium in hyperglycemia-induced cardiac damage. Cardiovasc Diabetol (2010) 0.92
Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes. Circ Res (2016) 0.92
Reversal of mitochondrial proteomic loss in Type 1 diabetic heart with overexpression of phospholipid hydroperoxide glutathione peroxidase. Am J Physiol Regul Integr Comp Physiol (2013) 0.90
Cardioprotective effects of gallic acid in diabetes-induced myocardial dysfunction in rats. Pharmacognosy Res (2011) 0.90
Regulation of mitochondrial processes: a target for heart failure. Drug Discov Today Dis Mech (2010) 0.89
Impairment of aldehyde dehydrogenase-2 by 4-hydroxy-2-nonenal adduct formation and cardiomyocyte hypertrophy in mice fed a high-fat diet and injected with low-dose streptozotocin. Exp Biol Med (Maywood) (2014) 0.88
Upregulation of eNOS and unchanged energy metabolism in increased susceptibility of the aging type 2 diabetic GK rat heart to ischemic injury. Am J Physiol Heart Circ Physiol (2010) 0.87
Cardiac-specific overexpression of HIF-1{alpha} prevents deterioration of glycolytic pathway and cardiac remodeling in streptozotocin-induced diabetic mice. Am J Pathol (2010) 0.86
Mitochondrial targeted coenzyme Q, superoxide, and fuel selectivity in endothelial cells. PLoS One (2009) 0.85
Alterations in sarcoplasmic reticulum and mitochondrial functions in diabetic cardiomyopathy. Exp Clin Cardiol (2012) 0.84
Improvement of mechanical heart function by trimetazidine in db/db mice. Acta Pharmacol Sin (2010) 0.84
Modulation of potassium currents by angiotensin and oxidative stress in cardiac cells from the diabetic rat. J Physiol (2005) 0.84
Impaired translocation and activation of mitochondrial Akt1 mitigated mitochondrial oxidative phosphorylation Complex V activity in diabetic myocardium. J Mol Cell Cardiol (2013) 0.84
Enhanced skeletal muscle expression of extracellular superoxide dismutase mitigates streptozotocin-induced diabetic cardiomyopathy by reducing oxidative stress and aberrant cell signaling. Circ Heart Fail (2014) 0.83
Organic nitrates and nitrate resistance in diabetes: the role of vascular dysfunction and oxidative stress with emphasis on antioxidant properties of pentaerithrityl tetranitrate. Exp Diabetes Res (2010) 0.83
Identification by a differential proteomic approach of the induced stress and redox proteins by resveratrol in the normal and diabetic rat heart. J Cell Mol Med (2008) 0.81
Present Insights on Cardiomyopathy in Diabetic Patients. Curr Diabetes Rev (2016) 0.81
Electrical stimulation of cardiomyocytes activates mitochondrial matrix metalloproteinase causing electrical remodeling. Biochem Biophys Res Commun (2010) 0.80
Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy. Diabetes (2015) 0.80
Mouse Models of Oxidative Stress Indicate a Role for Modulating Healthy Aging. J Clin Exp Pathol (2012) 0.80
How exercise may amend metabolic disturbances in diabetic cardiomyopathy. Antioxid Redox Signal (2015) 0.80
Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy. Free Radic Biol Med (2015) 0.80
Mitochondrial dynamics in diabetic cardiomyopathy. Antioxid Redox Signal (2015) 0.79
No correlation between the p38 MAPK pathway and the contractile dysfunction in diabetic cardiomyocytes: hyperglycaemia-induced signalling and contractile function. Pflugers Arch (2005) 0.78
Riboflavin alleviates cardiac failure in Type I diabetic cardiomyopathy. Heart Int (2011) 0.78
Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus. Virulence (2016) 0.78
Cobalt protoporphyrin induces HO-1 expression mediated partially by FOXO1 and reduces mitochondria-derived reactive oxygen species production. PLoS One (2013) 0.78
Protective mechanisms of mitochondria and heart function in diabetes. Antioxid Redox Signal (2015) 0.78
Metabolic alterations induce oxidative stress in diabetic and failing hearts: different pathways, same outcome. Antioxid Redox Signal (2015) 0.78
Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome. J Mol Cell Cardiol (2015) 0.78
The role of CaMKII in diabetic heart dysfunction. Heart Fail Rev (2015) 0.77
Mitochondrial dysfunction and its impact on diabetic heart. Biochim Biophys Acta (2016) 0.76
Role of Serum Biomarkers in Early Detection of Diabetic Cardiomyopathy in the West Virginian Population. Int J Med Sci (2016) 0.75
Metabolic Remodeling in Diabetic Cardiomyopathy. Cardiovasc Res (2017) 0.75
Maternal Engineered Nanomaterial Exposure Disrupts Progeny Cardiac Function and Bioenergetics. Am J Physiol Heart Circ Physiol (2016) 0.75
Dihydromyricetin Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Mice. Biomed Res Int (2017) 0.75
Intravenous Administration of Lycopene, a Tomato Extract, Protects against Myocardial Ischemia-Reperfusion Injury. Nutrients (2016) 0.75
Aleglitazar, a dual peroxisome proliferator-activated receptor-α and -γ agonist, protects cardiomyocytes against the adverse effects of hyperglycaemia. Diab Vasc Dis Res (2017) 0.75
The role of Dermcidin isoform-2 in the occurrence and severity of Diabetes. Sci Rep (2017) 0.75
Open mass spectrometry search algorithm. J Proteome Res (2004) 15.25
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell (2010) 5.83
Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency. Cancer Res (2004) 2.79
BUBR1 deficiency results in abnormal megakaryopoiesis. Blood (2003) 2.31
Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3. Mol Cell (2009) 2.27
The stented elephant trunk procedure combined total arch replacement for Debakey I aortic dissection: operative result and follow-up. Interact Cardiovasc Thorac Surg (2010) 2.19
Activity-dependent modulation of limbic dopamine D3 receptors by CaMKII. Neuron (2009) 2.14
Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy. Diabetes (2006) 2.12
Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes. Am J Physiol Endocrinol Metab (2004) 2.03
Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction. Circulation (2009) 2.03
Prevalence of nonalcoholic fatty liver disease and its metabolic risk factors in women of different ages and body mass index. Menopause (2015) 1.98
Podocyte-specific overexpression of the antioxidant metallothionein reduces diabetic nephropathy. J Am Soc Nephrol (2008) 1.94
Erythropoietin ameliorates renal ischemia and reperfusion injury via inhibiting tubulointerstitial inflammation. J Surg Res (2011) 1.85
AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function. J Clin Invest (2013) 1.84
Cocaine-induced intracellular signaling and gene expression are oppositely regulated by the dopamine D1 and D3 receptors. J Neurosci (2004) 1.80
Lack of self-administration of cocaine in dopamine D1 receptor knock-out mice. J Neurosci (2007) 1.73
Metallothionein abrogates GTP cyclohydrolase I inhibition-induced cardiac contractile and morphological defects: role of mitochondrial biogenesis. Hypertension (2009) 1.72
Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin. Nature (2012) 1.69
Forest thinning and soil respiration in a ponderosa pine plantation in the Sierra Nevada. Tree Physiol (2005) 1.68
Development of late-stage diabetic nephropathy in OVE26 diabetic mice. Diabetes (2004) 1.65
Ultrastructural remodelling of Ca(2+) signalling apparatus in failing heart cells. Cardiovasc Res (2012) 1.65
Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes. Cardiovasc Res (2011) 1.64
Overexpression of metallothionein reduces diabetic cardiomyopathy. Diabetes (2002) 1.61
Control of autophagy maturation by acid sphingomyelinase in mouse coronary arterial smooth muscle cells: protective role in atherosclerosis. J Mol Med (Berl) (2014) 1.59
Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm. Cell (2013) 1.56
c-Fos facilitates the acquisition and extinction of cocaine-induced persistent changes. J Neurosci (2006) 1.55
c-fos regulates neuronal excitability and survival. Nat Genet (2002) 1.45
Comparative study of on-pump and off-pump coronary bypass surgery in patients with triple-vessel coronary artery disease. Chin Med J (Engl) (2004) 1.44
Bcl-2 enhances the formation of newborn striatal long-projection neurons in adult rat brain after a transient ischemic stroke. Neurosci Bull (2012) 1.42
Development of a rapid, simple dipstick dye immunoassay for schistosomiasis diagnosis. J Immunol Methods (2002) 1.42
Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production. Diabetes (2003) 1.41
Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy. Proc Natl Acad Sci U S A (2009) 1.40
High-fat diet-induced juvenile obesity leads to cardiomyocyte dysfunction and upregulation of Foxo3a transcription factor independent of lipotoxicity and apoptosis. J Hypertens (2006) 1.39
[Idiopathic CD4+ T-lymphocytopenia in a child with disseminated cryptococcosis]. Zhonghua Er Ke Za Zhi (2005) 1.39
Osteopontin level correlates with acute cellular renal allograft rejection. J Surg Res (2012) 1.38
lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI. FEBS J (2014) 1.36
The dopamine D1 receptor is a critical mediator for cocaine-induced gene expression. J Neurochem (2002) 1.34
Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination. Cell (2013) 1.32
Overexpression of aldehyde dehydrogenase-2 (ALDH2) transgene prevents acetaldehyde-induced cell injury in human umbilical vein endothelial cells: role of ERK and p38 mitogen-activated protein kinase. J Biol Chem (2004) 1.31
Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs. Structure (2006) 1.31
Functional integration of newly generated neurons into striatum after cerebral ischemia in the adult rat brain. Stroke (2008) 1.28
Metallothionein alleviates glutathione depletion-induced oxidative cardiomyopathy in murine hearts. Crit Care Med (2008) 1.27
Podocyte loss in aging OVE26 diabetic mice. Anat Rec (Hoboken) (2008) 1.26
Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species. J Biol Chem (2003) 1.26
Apoptotic DNA fragmentation and tissue homeostasis. Trends Cell Biol (2002) 1.25
An ultra-short dopamine pathway regulates basal ganglia output. J Neurosci (2009) 1.23
Metformin attenuates cardiac fibrosis by inhibiting the TGFbeta1-Smad3 signalling pathway. Cardiovasc Res (2010) 1.21
Waste oil derived biofuels in China bring brightness for global GHG mitigation. Bioresour Technol (2012) 1.21
Overexpression of alcohol dehydrogenase exacerbates ethanol-induced contractile defect in cardiac myocytes. Am J Physiol Heart Circ Physiol (2002) 1.20
Cardiac overexpression of alcohol dehydrogenase exacerbates cardiac contractile dysfunction, lipid peroxidation, and protein damage after chronic ethanol ingestion. Alcohol Clin Exp Res (2003) 1.20
Erythropoietin prevents the acute myocardial inflammatory response induced by ischemia/reperfusion via induction of AP-1. Cardiovasc Res (2005) 1.19
MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity. Diabetes (2005) 1.17
Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes. J Biol Chem (2013) 1.15
Increase in cerebellar neurotrophin-3 and oxidative stress markers in autism. Cerebellum (2009) 1.15
Repeated cocaine administration induces gene expression changes through the dopamine D1 receptors. Neuropsychopharmacology (2005) 1.15
Beta-cell death and proliferation after intermittent hypoxia: role of oxidative stress. Free Radic Biol Med (2008) 1.14
Gain-of-function mutations in SCN11A cause familial episodic pain. Am J Hum Genet (2013) 1.14
Effect of Gosha-jinki-gan (Chinese herbal medicine: Niu-Che-Sen-Qi-Wan) on insulin resistance in streptozotocin-induced diabetic rats. Diabetes Res Clin Pract (2003) 1.13
7-OH-DPAT and PD 128907 selectively activate the D3 dopamine receptor in a novel environment. Neuropsychopharmacology (2003) 1.13
Stress-induced changes in nucleus accumbens glutamate synaptic plasticity. J Neurophysiol (2009) 1.13
[In vivo and in vitro study on the effect of excessive fluoride on type I collagen of rats]. Wei Sheng Yan Jiu (2002) 1.12
Telocytes in the human kidney cortex. J Cell Mol Med (2012) 1.12
Metallothionein and catalase sensitize to diabetes in nonobese diabetic mice: reactive oxygen species may have a protective role in pancreatic beta-cells. Diabetes (2006) 1.11
Marginal resection for osteosarcoma with effective preoperative chemotherapy. Orthop Surg (2009) 1.11
Arabidopsis COBRA-LIKE 10, a GPI-anchored protein, mediates directional growth of pollen tubes. Plant J (2013) 1.10
Brain region-specific changes in oxidative stress and neurotrophin levels in autism spectrum disorders (ASD). Cerebellum (2011) 1.10
4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6. J Med Chem (2010) 1.08
Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes. Cell Physiol Biochem (2013) 1.08
Post-translational modification of POU domain transcription factor Oct-4 by SUMO-1. FASEB J (2007) 1.08
Life-cycle analysis on biodiesel production from microalgae: water footprint and nutrients balance. Bioresour Technol (2010) 1.08
In vivo suppression of microRNA-24 prevents the transition toward decompensated hypertrophy in aortic-constricted mice. Circ Res (2013) 1.07
Genetic analysis of six SNPs in candidate genes associated with high cross-race risk of development of thoracic aortic aneurysms and dissections in Chinese Han population. Acta Pharmacol Sin (2010) 1.07
Alterations in the renal elastin-elastase system in type 1 diabetic nephropathy identified by proteomic analysis. J Am Soc Nephrol (2004) 1.05
Ultrastructural uncoupling between T-tubules and sarcoplasmic reticulum in human heart failure. Cardiovasc Res (2013) 1.03
Potential role for Nrf2 activation in the therapeutic effect of MG132 on diabetic nephropathy in OVE26 diabetic mice. Am J Physiol Endocrinol Metab (2012) 1.03
Mutation of a single TMVI residue, Phe(282), in the beta(2)-adrenergic receptor results in structurally distinct activated receptor conformations. Biochemistry (2002) 1.02
Endonuclease G is required for early embryogenesis and normal apoptosis in mice. Proc Natl Acad Sci U S A (2003) 1.02
Therapeutic effect of MG-132 on diabetic cardiomyopathy is associated with its suppression of proteasomal activities: roles of Nrf2 and NF-κB. Am J Physiol Heart Circ Physiol (2012) 1.02
Proteomic characterization of larval and adult developmental stages in Echinococcus granulosus reveals novel insight into host-parasite interactions. J Proteomics (2013) 1.01
The protective effect of a Schistosoma japonicum Chinese strain 23 kDa plasmid DNA vaccine in pigs is enhanced with IL-12. Vaccine (2004) 1.00
Silicon nanowires for biosensing, energy storage, and conversion. Adv Mater (2013) 0.99
Ultrastructural morphometry of capillary basement membrane thickness in normal and transgenic diabetic mice. Anat Rec A Discov Mol Cell Evol Biol (2003) 0.99
Reconstitution of lysosomal NAADP-TRP-ML1 signaling pathway and its function in TRP-ML1(-/-) cells. Am J Physiol Cell Physiol (2011) 0.99
AICAR stimulates IL-6 production via p38 MAPK in cardiac fibroblasts in adult mice: a possible role for AMPK. Biochem Biophys Res Commun (2005) 0.99
FVB mouse genotype confers susceptibility to OVE26 diabetic albuminuria. Am J Physiol Renal Physiol (2010) 0.99
Application of dipstick dye immunoassay (DDIA) kit for the diagnosis of schistosomiasis mekongi. Acta Trop (2005) 0.99
Causes and characteristics of diabetic cardiomyopathy. Rev Diabet Stud (2006) 0.99
Dopamine D(1) and D(3) receptors oppositely regulate NMDA- and cocaine-induced MAPK signaling via NMDA receptor phosphorylation. J Neurochem (2007) 0.99
Genetic variation in PLCE1 is associated with gastric cancer survival in a Chinese population. J Gastroenterol (2011) 0.99
Stabilization of the μ-opioid receptor by truncated single transmembrane splice variants through a chaperone-like action. J Biol Chem (2013) 0.99
Angiotensin II plays a critical role in diabetic pulmonary fibrosis most likely via activation of NADPH oxidase-mediated nitrosative damage. Am J Physiol Endocrinol Metab (2011) 0.99