Ikuhiko Nakase

Author PubWeight™ 31.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 High-resolution multi-dimensional NMR spectroscopy of proteins in human cells. Nature 2009 2.06
2 Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans. Bioconjug Chem 2008 1.46
3 Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34+ leukaemia cells. Biochem J 2007 1.44
4 Translocation of branched-chain arginine peptides through cell membranes: flexibility in the spatial disposition of positive charges in membrane-permeable peptides. Biochemistry 2002 1.21
5 Transient focal membrane deformation induced by arginine-rich peptides leads to their direct penetration into cells. Mol Ther 2012 1.16
6 Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine. J Control Release 2006 1.14
7 Intracellular traffic and fate of protein transduction domains HIV-1 TAT peptide and octaarginine. Implications for their utilization as drug delivery vectors. Bioconjug Chem 2006 1.12
8 Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system. Biochemistry 2004 1.02
9 Acylation of octaarginine: Implication to the use of intracellular delivery vectors. J Control Release 2010 0.94
10 Structural variety of membrane permeable peptides. Curr Protein Pept Sci 2003 0.91
11 Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas). J Control Release 2009 0.91
12 Unique features of a pH-sensitive fusogenic peptide that improves the transfection efficiency of cationic liposomes. J Gene Med 2005 0.90
13 Gramicidin-based channel systems for the detection of protein-ligand interaction. Bioorg Med Chem 2004 0.89
14 Acid wash in determining cellular uptake of Fab/cell-permeating peptide conjugates. Biopolymers 2007 0.89
15 Artemisinin-transferrin conjugate retards growth of breast tumors in the rat. Anticancer Res 2009 0.88
16 Cytosolic targeting of macromolecules using a pH-dependent fusogenic peptide in combination with cationic liposomes. Bioconjug Chem 2009 0.88
17 Collagen-like cell-penetrating peptides. Angew Chem Int Ed Engl 2013 0.86
18 Effect of the attachment of a penetration accelerating sequence and the influence of hydrophobicity on octaarginine-mediated intracellular delivery. Mol Pharm 2012 0.85
19 Effects of pyrenebutyrate on the translocation of arginine-rich cell-penetrating peptides through artificial membranes: recruiting peptides to the membranes, dissipating liquid-ordered phases, and inducing curvature. Biochim Biophys Acta 2013 0.84
20 Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD. J Control Release 2009 0.84
21 Arginine carrier peptide bearing Ni(II) chelator to promote cellular uptake of histidine-tagged proteins. Bioconjug Chem 2004 0.83
22 Novel system to achieve one-pot modification of cargo molecules with oligoarginine vectors for intracellular delivery. Bioconjug Chem 2009 0.83
23 Arginine-rich peptides: methods of translocation through biological membranes. Curr Pharm Des 2013 0.83
24 Effects of cell-permeating peptide binding on the distribution of 125I-labeled Fab fragment in rats. Bioconjug Chem 2006 0.82
25 CXCR4 stimulates macropinocytosis: implications for cellular uptake of arginine-rich cell-penetrating peptides and HIV. Chem Biol 2012 0.82
26 Expressed protein ligation for the preparation of fusion proteins with cell penetrating peptides for endotoxin removal and intracellular delivery. Biochim Biophys Acta 2010 0.80
27 Distribution of immunoglobulin Fab fragment conjugated with HIV-1 REV peptide following intravenous administration in rats. Mol Pharm 2006 0.79
28 Curvature engineering: positive membrane curvature induced by epsin N-terminal peptide boosts internalization of octaarginine. ACS Chem Biol 2013 0.79
29 Identification of cellular proteins interacting with octaarginine (R8) cell-penetrating peptide by photo-crosslinking. Bioorg Med Chem Lett 2013 0.79
30 Transduction of cell-penetrating peptides into induced pluripotent stem cells. Cell Transplant 2010 0.79
31 Rev-derived peptides inhibit HIV-1 replication by antagonism of Rev and a co-receptor, CXCR4. Int J Biochem Cell Biol 2010 0.78
32 Development of a novel nanoparticle by dual modification with the pluripotential cell-penetrating peptide PepFect6 for cellular uptake, endosomal escape, and decondensation of an siRNA core complex. Biopolymers 2013 0.77
33 RNase S complex bearing arginine-rich peptide and anti-HIV activity. J Mol Recognit 2005 0.75
34 Controlling leucine-zipper partner recognition in cells through modification of a-g interactions. Chem Commun (Camb) 2014 0.75
35 Studies on the effects of arginine residues introduced to peptide ribonucleic acids (PRNA) on the complex stability with RNA. Nucleic Acids Symp Ser (Oxf) 2009 0.75
36 Enhanced target-specific accumulation of radiolabeled antibodies by conjugating arginine-rich peptides as anchoring molecules. Bioconjug Chem 2010 0.75
37 Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells. Eur J Pharmacol 2012 0.75