Published in Brain Res on May 22, 2004
Neurotrophic and neuroprotective actions of estrogen: basic mechanisms and clinical implications. Steroids (2007) 2.56
Blood serum miRNA: non-invasive biomarkers for Alzheimer's disease. Exp Neurol (2011) 1.49
Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide. J Cereb Blood Flow Metab (2010) 1.36
Estradiol suppresses NF-kappa B activation through coordinated regulation of let-7a and miR-125b in primary human macrophages. J Immunol (2010) 1.32
Mitochondrial mechanisms of estrogen neuroprotection. Biochim Biophys Acta (2009) 1.25
Estrogens and progesterone as neuroprotectants: what animal models teach us. Front Biosci (2008) 1.25
Mechanisms of gender-linked ischemic brain injury. Restor Neurol Neurosci (2009) 1.24
Progesterone increases brain-derived neuroptrophic factor expression and protects against glutamate toxicity in a mitogen-activated protein kinase- and phosphoinositide-3 kinase-dependent manner in cerebral cortical explants. J Neurosci Res (2007) 1.22
Soluble epoxide hydrolase: regulation by estrogen and role in the inflammatory response to cerebral ischemia. Front Biosci (2008) 1.11
Gender and the injured brain. Anesth Analg (2008) 1.10
Estrogen, NFkappaB, and the heat shock response. Mol Med (2008) 1.09
The efficacy of edaravone (radicut), a free radical scavenger, for cardiovascular disease. Int J Mol Sci (2013) 1.07
Acute and chronic estradiol treatments reduce memory deficits induced by transient global ischemia in female rats. Horm Behav (2005) 1.07
Postinjury estrogen treatment of chronic spinal cord injury improves locomotor function in rats. J Neurosci Res (2010) 1.06
Sex, stroke, and inflammation: the potential for estrogen-mediated immunoprotection in stroke. Horm Behav (2012) 0.99
Estrogen modulates NFκB signaling by enhancing IκBα levels and blocking p65 binding at the promoters of inflammatory genes via estrogen receptor-β. PLoS One (2012) 0.96
Activation of nuclear factor-κB in the brain after experimental subarachnoid hemorrhage and its potential role in delayed brain injury. PLoS One (2013) 0.96
Age alters cerebrovascular inflammation and effects of estrogen. Am J Physiol Heart Circ Physiol (2007) 0.95
Intracellular mechanisms of N-acylethanolamine-mediated neuroprotection in a rat model of stroke. Neuroscience (2009) 0.94
Inhibition of vascular inflammation by dehydroepiandrosterone sulfate in human aortic endothelial cells: roles of PPARalpha and NF-kappaB. Vascul Pharmacol (2007) 0.91
Neuronal estrogen receptor-alpha mediates neuroprotection by 17beta-estradiol. J Cereb Blood Flow Metab (2009) 0.89
Idiopathic cystitis in domestic cats--beyond the lower urinary tract. J Vet Intern Med (2011) 0.89
Administration of low dose estrogen attenuates persistent inflammation, promotes angiogenesis, and improves locomotor function following chronic spinal cord injury in rats. J Neurochem (2016) 0.89
The COMT Val158 Met polymorphism as an associated risk factor for Alzheimer disease and mild cognitive impairment in APOE 4 carriers. BMC Neurosci (2009) 0.88
Lauroylethanolamide and linoleoylethanolamide improve functional outcome in a rodent model for stroke. Neurosci Lett (2011) 0.88
The role of estrogen receptor subtypes in ameliorating hepatic injury following trauma-hemorrhage. J Hepatol (2007) 0.86
Inhibition of nuclear factor-κB by 6-O-acetyl shanzhiside methyl ester protects brain against injury in a rat model of ischemia and reperfusion. J Neuroinflammation (2010) 0.86
Estrogen signaling in metabolic inflammation. Mediators Inflamm (2014) 0.85
Mild Hypothermia Attenuates Intercellular Adhesion Molecule-1 Induction via Activation of Extracellular Signal-Regulated Kinase-1/2 in a Focal Cerebral Ischemia Model. Stroke Res Treat (2011) 0.85
Nuclear factor kappa B in the dorsal raphe of macaques: an anatomical link for steroids, cytokines and serotonin. J Psychiatry Neurosci (2006) 0.84
Changes in N-acylethanolamine Pathway Related Metabolites in a Rat Model of Cerebral Ischemia/Reperfusion. J Glycomics Lipidomics (2015) 0.81
Mechanisms of estrogens' dose-dependent neuroprotective and neurodamaging effects in experimental models of cerebral ischemia. Int J Mol Sci (2011) 0.81
Stroke neuroprotection: oestrogen and insulin-like growth factor-1 interactions and the role of microglia. J Neuroendocrinol (2013) 0.80
Aldose reductase inhibition ameliorates the detrimental effect of estrogen replacement therapy on neuropathology in diabetic rats subjected to transient forebrain ischemia. Brain Res (2010) 0.78
Gender differences in hepatic ischemic reperfusion injury in rats are associated with endothelial cell nitric oxide synthase-derived nitric oxide. World J Gastroenterol (2005) 0.78
Melatonin and oestrogen treatments were able to improve neuroinflammation and apoptotic processes in dentate gyrus of old ovariectomized female rats. Age (Dordr) (2014) 0.77
Shock wave induces chronic renal lesion through activation of the nuclear factor kappa B signaling pathway. World J Urol (2010) 0.77
Soluble epoxide hydrolase gene deletion improves blood flow and reduces infarct size after cerebral ischemia in reproductively senescent female mice. Front Pharmacol (2015) 0.77
The components of Huang-Lian-Jie-Du-Decoction act synergistically to exert protective effects in a rat ischemic stroke model. Oncotarget (2016) 0.76
17beta-estradiol protects male mice from cuprizone-induced demyelination and oligodendrocyte loss. Neurobiol Dis (2010) 0.76
Effects of sex steroid hormones on neuromedin S and neuromedin U2 receptor expression following experimental traumatic brain injury. Iran J Basic Med Sci (2016) 0.75
Bindarit reduces the incidence of acute aortic dissection complicated lung injury via modulating NF-κB pathway. Exp Ther Med (2017) 0.75
A roadmap for the prevention of dementia II: Leon Thal Symposium 2008. Alzheimers Dement (2009) 10.21
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. Cell (2007) 6.47
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab (2008) 6.22
Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity. Neuron (2007) 3.98
Choroidal thickness in both eyes of patients with unilateral idiopathic macular hole. Ophthalmology (2012) 2.78
Mitochondrial localization of estrogen receptor beta. Proc Natl Acad Sci U S A (2004) 2.15
Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction. Proc Natl Acad Sci U S A (2008) 1.97
Choroidal thickness in healthy Chinese subjects. Invest Ophthalmol Vis Sci (2011) 1.74
Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell (2013) 1.71
Increased beta-secretase activity and expression in rats following transient cerebral ischemia. Brain Res (2004) 1.59
Ratios of activated matrix metalloproteinase-9 to tissue inhibitor of matrix metalloproteinase-1 in wound fluids are inversely correlated with healing of pressure ulcers. Wound Repair Regen (2002) 1.51
Alternative mitochondrial electron transfer as a novel strategy for neuroprotection. J Biol Chem (2011) 1.41
Cyclic mechanical stretching of human tendon fibroblasts increases the production of prostaglandin E2 and levels of cyclooxygenase expression: a novel in vitro model study. Connect Tissue Res (2003) 1.39
Quinol-based cyclic antioxidant mechanism in estrogen neuroprotection. Proc Natl Acad Sci U S A (2003) 1.37
A broadly flavivirus cross-neutralizing monoclonal antibody that recognizes a novel epitope within the fusion loop of E protein. PLoS One (2011) 1.36
Testosterone increases neurotoxicity of glutamate in vitro and ischemia-reperfusion injury in an animal model. J Appl Physiol (1985) (2002) 1.35
De novo sequencing and analysis of root transcriptome using 454 pyrosequencing to discover putative genes associated with drought tolerance in Ammopiptanthus mongolicus. BMC Genomics (2012) 1.29
Pyruvate protects mitochondria from oxidative stress in human neuroblastoma SK-N-SH cells. Brain Res (2006) 1.28
Mitochondrial mechanisms of estrogen neuroprotection. Biochim Biophys Acta (2009) 1.25
Estrogens and progesterone as neuroprotectants: what animal models teach us. Front Biosci (2008) 1.25
Distinct intracellular calcium transients in neurites and somata integrate neuronal signals. J Neurosci (2002) 1.24
Proteolytic cleavage and nuclear translocation of fibrocystin is regulated by intracellular Ca2+ and activation of protein kinase C. J Biol Chem (2006) 1.22
Estrogens directly potentiate neuronal L-type Ca2+ channels. Proc Natl Acad Sci U S A (2008) 1.22
Cdk5 is involved in NFT-like tauopathy induced by transient cerebral ischemia in female rats. Biochim Biophys Acta (2006) 1.20
17beta-Estradiol attenuates blood-brain barrier disruption induced by cerebral ischemia-reperfusion injury in female rats. Brain Res (2005) 1.18
Differential expression profiles of microRNAs as potential biomarkers for the early diagnosis of esophageal squamous cell carcinoma. Oncol Rep (2012) 1.16
The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line. Mol Neurodegener (2009) 1.16
A method for generating uniform size-segregated pyrite particle fractions. Geochem Trans (2007) 1.16
Neuroprotective effects of an estratriene analog are estrogen receptor independent in vitro and in vivo. Brain Res (2005) 1.16
Oxidative damage to human lens epithelial cells in culture: estrogen protection of mitochondrial potential, ATP, and cell viability. Invest Ophthalmol Vis Sci (2003) 1.15
Controlled electrochemical synthesis of conductive polymer nanotube structures. J Am Chem Soc (2007) 1.14
Methylene blue as a cerebral metabolic and hemodynamic enhancer. PLoS One (2012) 1.12
Nano-embossing technology on ferroelectric thin film Pb(Zr0.3,Ti0.7)O3 for multi-bit storage application. Nanoscale Res Lett (2011) 1.12
Estrogen-like compounds for ischemic neuroprotection. Stroke (2004) 1.10
Different impacts of blood pressure variability on the progression of cerebral microbleeds and white matter lesions. Stroke (2012) 1.10
Transcriptional profiling of mammary gland in Holstein cows with extremely different milk protein and fat percentage using RNA sequencing. BMC Genomics (2014) 1.09
Novel mechanisms for estrogen-induced neuroprotection. Exp Biol Med (Maywood) (2006) 1.09
Structure-nongenomic neuroprotection relationship of estrogens and estrogen-derived compounds. Pharmacol Ther (2007) 1.09
Role of PPAR-gamma ligands in neuroprotection against glutamate-induced cytotoxicity in retinal ganglion cells. Invest Ophthalmol Vis Sci (2003) 1.09
Effects of Vesl/Homer proteins on intracellular signaling. Exp Biol Med (Maywood) (2005) 1.09
Mitochondria play a central role in estrogen-induced neuroprotection. Curr Drug Targets CNS Neurol Disord (2005) 1.08
Transient cerebral ischemia induces site-specific hyperphosphorylation of tau protein. Brain Res (2004) 1.08
Transient cerebral ischemia induces aberrant neuronal cell cycle re-entry and Alzheimer's disease-like tauopathy in female rats. J Biol Chem (2004) 1.07
Immunohistochemical localization of EGF, TGF-alpha, TGF-beta, and their receptors in rat corneas during healing of excimer laser ablation. Curr Eye Res (2006) 1.07
Biochemical and proteomics approaches to characterize topoisomerase IIalpha cysteines and DNA as targets responsible for cisplatin-induced inhibition of topoisomerase IIalpha. Mol Pharmacol (2004) 1.07
Neuroprotective effects of 17beta-estradiol and nonfeminizing estrogens against H2O2 toxicity in human neuroblastoma SK-N-SH cells. Mol Pharmacol (2006) 1.06
Evaluating uncertainty to strengthen epidemiologic data for use in human health risk assessments. Environ Health Perspect (2014) 1.06
The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity. Int J Biochem Cell Biol (2007) 1.05
Estrogen protects the inner retina from apoptosis and ischemia-induced loss of Vesl-1L/Homer 1c immunoreactive synaptic connections. Invest Ophthalmol Vis Sci (2003) 1.05
Synthesis and antitumor efficacy of daunorubicin-loaded magnetic nanoparticles. Int J Nanomedicine (2011) 1.05
Metalloprotease-mediated GH receptor proteolysis and GHBP shedding. Determination of extracellular domain stem region cleavage site. J Biol Chem (2002) 1.03
Reversing the Warburg effect as a treatment for glioblastoma. J Biol Chem (2013) 1.02
Estrogen receptor beta as a mitochondrial vulnerability factor. J Biol Chem (2009) 1.02
Combination therapy of 17beta-estradiol and recombinant tissue plasminogen activator for experimental ischemic stroke. J Pharmacol Exp Ther (2009) 1.02
Vesl/Homer proteins regulate ryanodine receptor type 2 function and intracellular calcium signaling. Cell Calcium (2003) 1.02
Mechanistic investigations on the antioxidant action of a neuroprotective estrogen derivative. Steroids (2007) 1.02
Rapid mitochondrial dysfunction mediates TNF-alpha-induced neurotoxicity. J Neurochem (2015) 1.01
Multifunctional magnetic Fe3O4 nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance. Int J Nanomedicine (2012) 1.01
Autophagy is activated and might protect neurons from degeneration after traumatic brain injury. Neurosci Bull (2008) 1.01
Neuroprotective effects of a novel non-receptor-binding estrogen analogue: in vitro and in vivo analysis. Stroke (2002) 1.01
Lipid profiling reveals tissue-specific differences for ethanolamide lipids in mice lacking fatty acid amide hydrolase. Lipids (2010) 1.00
Differential functional interaction of two Vesl/Homer protein isoforms with ryanodine receptor type 1: a novel mechanism for control of intracellular calcium signaling. Cell Calcium (2003) 1.00
A prototypical Sigma-1 receptor antagonist protects against brain ischemia. Brain Res (2007) 0.99
Neuroprotective actions of methylene blue and its derivatives. PLoS One (2012) 0.99
Comparison of intravascular ultrasound versus angiography-guided drug-eluting stent implantation: a meta-analysis of one randomised trial and ten observational studies involving 19,619 patients. EuroIntervention (2012) 0.99
Dietary activators of Sirt1. Mol Cell Endocrinol (2008) 0.98
Quantification of deficits in spatial visual function of mouse models for glaucoma. Invest Ophthalmol Vis Sci (2011) 0.97
Subcellular distribution of native estrogen receptor alpha and beta subtypes in cultured human lens epithelial cells. Exp Eye Res (2004) 0.97