Published in J Clin Pharmacol on June 01, 2004
Role of plain abdominal radiographs in predicting type of congenital pouch colon. Pediatr Radiol (2010) 0.94
High-performance liquid chromatographic determination of rivastigmine in human plasma for application in pharmacokinetic studies. Iran J Pharm Res (2010) 0.80
The use of gastrointestinal intubation studies for controlled release development. Br J Clin Pharmacol (2009) 0.75
High performance liquid chromatographic fluorescence detection method for the quantification of rivastigmine in rat plasma and brain: application to preclinical pharmacokinetic studies in rats. J Young Pharm (2011) 0.75
Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412. Blood (2004) 3.84
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study. Blood (2008) 2.76
Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain. Blood (2005) 2.44
Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08. Clin Cancer Res (2006) 2.44
Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors. Blood (2006) 2.18
Imatinib plasma levels are correlated with clinical benefit in patients with unresectable/metastatic gastrointestinal stromal tumors. J Clin Oncol (2009) 2.16
GFR prediction using the MDRD and Cockcroft and Gault equations in patients with end-stage renal disease. Nephrol Dial Transplant (2005) 1.96
Phase I trial of imatinib in children with newly diagnosed brainstem and recurrent malignant gliomas: a Pediatric Brain Tumor Consortium report. Neuro Oncol (2007) 1.84
Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation. Blood (2005) 1.83
Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of renal dysfunction: a study by the National Cancer Institute Organ Dysfunction Working Group. J Clin Oncol (2008) 1.69
Improved renal ischemia tolerance in females influences kidney transplantation outcomes. J Clin Invest (2016) 1.51
Complete Genome Sequence of a Channel Catfish Epidemic Isolate, Aeromonas hydrophila Strain ML09-119. Genome Announc (2013) 1.42
Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study. Epilepsia (2015) 1.40
Use of the femoral artery route for placement of temporary catheters for emergency haemodialysis when all usual central venous access sites are exhausted. Nephrol Dial Transplant (2008) 1.38
Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection. BMC Med (2010) 1.26
Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. J Cell Biol (2009) 1.23
Phospholipase cbeta is critical for T cell chemotaxis. J Immunol (2007) 1.22
The relative role of PLCbeta and PI3Kgamma in platelet activation. Blood (2005) 1.09
A novel testis ubiquitin-binding protein gene arose by exon shuffling in hominoids. Genome Res (2007) 1.07
Pharmacokinetics of a rivastigmine transdermal patch formulation in healthy volunteers: relative effects of body site application. J Clin Pharmacol (2007) 1.02
Pharmacokinetics and bioavailability of the novel rivastigmine transdermal patch versus rivastigmine oral solution in healthy elderly subjects. J Clin Pharmacol (2008) 1.00
Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis. Blood (2009) 0.96
Small interfering RNA-directed knockdown of S100A4 decreases proliferation and invasiveness of osteosarcoma cells. Cancer Lett (2010) 0.92
Estimation of the absolute bioavailability of rivastigmine in patients with mild to moderate dementia of the Alzheimer's type. Clin Pharmacokinet (2002) 0.92
Pharmacokinetics of methylphenidate after oral administration of two modified-release formulations in healthy adults. Clin Pharmacokinet (2003) 0.92
A mechanism-based population pharmacokinetic model for characterizing time-dependent pharmacokinetics of midostaurin and its metabolites in human subjects. Clin Pharmacokinet (2008) 0.92
In situ axially doped n-channel silicon nanowire field-effect transistors. Nano Lett (2008) 0.92
Pharmacokinetic-pharmacodynamic comparison of a novel multiligand somatostatin analog, SOM230, with octreotide in patients with acromegaly. Clin Pharmacol Ther (2005) 0.92
Plasma exposure of imatinib and its correlation with clinical response in the Tyrosine Kinase Inhibitor Optimization and Selectivity Trial. Haematologica (2012) 0.89
Safety, tolerability, and pharmacokinetics of a single dose of pasireotide long-acting release in healthy volunteers: a single-center Phase I study. Eur J Endocrinol (2012) 0.88
Pharmacokinetic and pharmacodynamic basis for effective argatroban dosing in pediatrics. J Clin Pharmacol (2010) 0.87
A first-in-man study to evaluate the safety, tolerability, and pharmacokinetics of pasireotide (SOM230), a multireceptor-targeted somatostatin analog, in healthy volunteers. Drug Des Devel Ther (2012) 0.87
Pasireotide (SOM230), a novel multireceptor-targeted somatostatin analogue, is well tolerated when administered as a continuous 7-day subcutaneous infusion in healthy male volunteers. J Clin Pharmacol (2011) 0.86
Meclizine metabolism and pharmacokinetics: formulation on its absorption. J Clin Pharmacol (2011) 0.86
Comparison of two endogenous biomarkers of CYP3A4 activity in a drug-drug interaction study between midostaurin and rifampicin. Eur J Clin Pharmacol (2014) 0.86
Midostaurin does not prolong cardiac repolarization defined in a thorough electrocardiogram trial in healthy volunteers. Cancer Chemother Pharmacol (2012) 0.85
Detoxification of the cruciferous phytoalexin brassinin in Sclerotinia sclerotiorum requires an inducible glucosyltransferase. Phytochemistry (2004) 0.84
Formal carbene insertion into C-C bond: Rh(I)-catalyzed reaction of benzocyclobutenols with diazoesters. J Am Chem Soc (2014) 0.84
Effects of imatinib mesylate on the pharmacokinetics of paracetamol (acetaminophen) in Korean patients with chronic myelogenous leukaemia. Br J Clin Pharmacol (2011) 0.83
Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions. Cancer Chemother Pharmacol (2012) 0.83
Investigation into CYP3A4-mediated drug-drug interactions on midostaurin in healthy volunteers. Cancer Chemother Pharmacol (2013) 0.82
Side effects of oseltamivir in end-stage renal failure patients. Nephrol Dial Transplant (2010) 0.82
Silicidation of silicon nanowires by platinum. Nano Lett (2007) 0.81
High-resolution frequency measurement method with a wide-frequency range based on a quantized phase step law. IEEE Trans Ultrason Ferroelectr Freq Control (2013) 0.81
Pharmacokinetic drug interactions in children taking oxcarbazepine. Clin Pharmacol Ther (2003) 0.80
An open-label dose-escalation study of once-daily and twice-daily pasireotide in healthy volunteers: safety, tolerability, and effects on glucose, insulin, and glucagon levels. Am J Ther (2014) 0.80
Steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease not affected by co-administration of memantine: an open-label, crossover, single-centre study. Clin Drug Investig (2008) 0.80
Potential of a renin inhibitory peptide from the red seaweed Palmaria palmata as a functional food ingredient following confirmation and characterization of a hypotensive effect in spontaneously hypertensive rats. J Agric Food Chem (2014) 0.80
Influence of enzyme-inducing antiepileptic drugs on trough level of imatinib in glioblastoma patients. Curr Clin Pharmacol (2008) 0.79
In vitro dissolution and in vivo oral absorption of methylphenidate from a bimodal release formulation in healthy volunteers. Biopharm Drug Dispos (2004) 0.79
Similar rivastigmine pharmacokinetics and pharmacodynamics in Japanese and white healthy participants following the application of novel rivastigmine patch. J Clin Pharmacol (2009) 0.79
Multiple once-daily subcutaneous doses of pasireotide were well tolerated in healthy male volunteers: a randomized, double-blind, placebo-controlled, cross-over, Phase I study. Endocrine (2012) 0.78
Effects of patupilone on the pharmacokinetics and pharmacodynamics of warfarin in patients with advanced malignancies: a phase I clinical trial. Mol Cancer Ther (2011) 0.78
PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization. Blood (2006) 0.78
Kinetics of pulmonary immune cells, antibody responses and their correlations with the viral clearance of influenza A fatal infection in mice. Virol J (2014) 0.77
Tolerability and dose proportional pharmacokinetics of pasireotide administered as a single dose or two divided doses in healthy male volunteers: a single-center, open-label, ascending-dose study. Clin Ther (2012) 0.77
Metabolism of crucifer phytoalexins in Sclerotinia sclerotiorum: detoxification of strongly antifungal compounds involves glucosylation. Org Biomol Chem (2006) 0.77
Pharmacokinetics and interactions of a novel antagonist of chemokine receptor 5 (CCR5) with ritonavir in rats and monkeys: role of CYP3A and P-glycoprotein. J Pharmacol Exp Ther (2003) 0.77
Bioavailability of modified-release methylphenidate: influence of high-fat breakfast when administered intact and when capsule content sprinkled on applesauce. Biopharm Drug Dispos (2003) 0.77
Bioavailability enhancement of glucosamine hydrochloride by chitosan. Int J Pharm (2013) 0.77
Aggregation of wedge-shaped perylenetetracarboxylic diimides with a different number of hydrophobic long alkyl chains. J Colloid Interface Sci (2010) 0.76
Effect of hepatic impairment on the pharmacokinetics of pasireotide (SOM230): results from a multicenter phase I study. J Clin Pharmacol (2012) 0.76
Application of physiologically based absorption modeling to formulation development of a low solubility, low permeability weak base: mechanistic investigation of food effect. AAPS PharmSciTech (2014) 0.76
[Expression and clinical significance of CD8+natural killer T cell stimulatory receptor NKG2D in peripheral blood of lung cancer patients]. Zhongguo Fei Ai Za Zhi (2010) 0.76
Recombinant Goat VEGF164 Increases Hair Growth by Painting Process on the Skin of Shaved Mouse. Asian-Australas J Anim Sci (2014) 0.75
6-Meth-oxy-meth-oxy-7-trifluoro-methyl-1,3-benzodioxole-5-carbaldehyde. Acta Crystallogr Sect E Struct Rep Online (2012) 0.75
Traumatic brain injury management can improve in primary care centre in remote area with minimum health assistance by proper training. J Neurosci Rural Pract (2013) 0.75
Application of melt granulation technology using twin-screw extruder in development of high-dose modified-release tablet formulation. J Pharm Sci (2010) 0.75
Identification of metabolites of a substance P (neurokinin 1 receptor) antagonist in rat hepatocytes and rat plasma. Drug Metab Dispos (2002) 0.75
Design, synthesis, and evaluation of potential inhibitors of brassinin glucosyltransferase, a phytoalexin detoxifying enzyme from Sclerotinia sclerotiorum. Bioorg Med Chem (2007) 0.75
Clinical evaluation of pazopanib eye drops in healthy subjects and in subjects with neovascular age-related macular degeneration. Retina (2014) 0.75
[EFFICACY COMPARISON BETWEEN DEEP MEDIAL COLLATERAL LIGAMENT REPAIR AND CONSERVATIVE TREATMENT FOR COMPLETE MEDIAL COLLATERAL LIGAMENT RUPTURE]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2016) 0.75
Supramolecular self-assembly study of a flexible perylenetetracarboxylic diimide dimer in Langmuir and Langmuir-Blodgett films. J Colloid Interface Sci (2008) 0.75
Detection of DNA damage induced by styrene oxide in dsDNA layer-by-layer films using adriamycin as electroactive probe. Colloids Surf B Biointerfaces (2009) 0.75
Hexa-peri-hexabenzocoronene-fluorene hybrid: A platform for highly soluble, easily functionalizable HBCs with expanded graphitic core. Angew Chem Int Ed Engl (2017) 0.75
Micro-Nanostructured Polyaniline Assembled in Cellulose Matrix via Interfacial Polymerization for Applications in Nerve Regeneration. ACS Appl Mater Interfaces (2016) 0.75
A facile cation exchange-based aqueous synthesis of highly stable and biocompatible Ag₂S quantum dots emitting in the second near-infrared biological window. Dalton Trans (2014) 0.75
Mesenteric Cyst Versus Lymphangioma: A Clinical Conundrum. Am J Med Sci (2015) 0.75
[Cloning and expression pattern of erk2 gene in Inner Mongolia Cashmere goat]. Sheng Wu Gong Cheng Xue Bao (2013) 0.75
Dose-proportional pharmacokinetics of d-threo-methylphenidate after a repeated-action release dosage form. J Clin Pharmacol (2007) 0.75
Photoinduced electron and energy transfer in dyads of porphyrin dimer and perylene tetracarboxylic diimide. Chemphyschem (2008) 0.75
Metabolism of patupilone in patients with advanced solid tumor malignancies. Invest New Drugs (2012) 0.75
[Effect of BMSCs transplantation on VEGF receptor fetal liver kinase 1 after spinal cord injury in rats]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2008) 0.75
MECP2 expression in gastric cancer and its correlation with clinical pathological parameters. Medicine (Baltimore) (2017) 0.75
Highly biocompatible nanofibrous microspheres self-assembled from chitin in NaOH/urea aqueous solution as cell carriers. Angew Chem Int Ed Engl (2015) 0.75