PubRank

David R Bevan

Author PubWeight™ 35.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structural determinants of substrate specificity in family 1 beta-glucosidases: novel insights from the crystal structure of sorghum dhurrinase-1, a plant beta-glucosidase with strict specificity, in complex with its natural substrate. J Biol Chem 2004 1.21
2 Assessing the stability of Alzheimer's amyloid protofibrils using molecular dynamics. J Phys Chem B 2010 1.14
3 GridMAT-MD: a grid-based membrane analysis tool for use with molecular dynamics. J Comput Chem 2009 1.11
4 Abscisic acid regulates inflammation via ligand-binding domain-independent activation of peroxisome proliferator-activated receptor gamma. J Biol Chem 2010 1.10
5 Structural insights into rice BGlu1 beta-glucosidase oligosaccharide hydrolysis and transglycosylation. J Mol Biol 2008 1.10
6 Herbivore-induced and floral homoterpene volatiles are biosynthesized by a single P450 enzyme (CYP82G1) in Arabidopsis. Proc Natl Acad Sci U S A 2010 1.08
7 Study and design of stability in GH5 cellulases. Biotechnol Bioeng 2011 1.02
8 Functional genomic analysis of Arabidopsis thaliana glycoside hydrolase family 35. Phytochemistry 2007 0.97
9 Practical considerations for building GROMOS-compatible small-molecule topologies. J Chem Inf Model 2010 0.97
10 Mutational and structural analysis of aglycone specificity in maize and sorghum beta-glucosidases. J Biol Chem 2003 0.95
11 Computational modeling-based discovery of novel classes of anti-inflammatory drugs that target lanthionine synthetase C-like protein 2. PLoS One 2012 0.95
12 Perturbation of membranes by the amyloid beta-peptide--a molecular dynamics study. FEBS J 2009 0.92
13 Molecular modeling of lanthionine synthetase component C-like protein 2: a potential target for the discovery of novel type 2 diabetes prophylactics and therapeutics. J Mol Model 2010 0.89
14 Destabilizing Alzheimer's Abeta(42) protofibrils with morin: mechanistic insights from molecular dynamics simulations. Biochemistry 2010 0.89
15 A comparative molecular dynamics analysis of the amyloid beta-peptide in a lipid bilayer. Arch Biochem Biophys 2007 0.89
16 Scopolin-hydrolyzing beta-glucosidases in roots of Arabidopsis. Plant Cell Physiol 2009 0.88
17 Virtual Screening as a Technique for PPAR Modulator Discovery. PPAR Res 2009 0.88
18 Lipid composition influences the release of Alzheimer's amyloid β-peptide from membranes. Protein Sci 2011 0.88
19 Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations. Protein Cell 2010 0.86
20 Fast identification of thermostable beta-glucosidase mutants on cellobiose by a novel combinatorial selection/screening approach. Biotechnol Bioeng 2009 0.85
21 Characterization of interactions between PilA from Pseudomonas aeruginosa strain K and a model membrane. J Phys Chem B 2011 0.85
22 Maize beta-glucosidase-aggregating factor is a polyspecific jacalin-related chimeric lectin, and its lectin domain is responsible for beta-glucosidase aggregation. J Biol Chem 2007 0.84
23 The role of molecular simulations in the development of inhibitors of amyloid β-peptide aggregation for the treatment of Alzheimer's disease. ACS Chem Neurosci 2012 0.82
24 Dietary α-eleostearic acid ameliorates experimental inflammatory bowel disease in mice by activating peroxisome proliferator-activated receptor-γ. PLoS One 2011 0.82
25 Morin inhibits the early stages of amyloid β-peptide aggregation by altering tertiary and quaternary interactions to produce "off-pathway" structures. Biochemistry 2012 0.81
26 Properties of β-thioglucoside hydrolases (TGG1 and TGG2) from leaves of Arabidopsis thaliana. Plant Sci 2012 0.81
27 Comparative characterization of the Arabidopsis subfamily a1 beta-galactosidases. Phytochemistry 2009 0.81
28 Modeling the relationship between the p53 C-terminal domain and its binding partners using molecular dynamics. J Phys Chem B 2010 0.80
29 The Arabidopsis At1g45130 and At3g52840 genes encode beta-galactosidases with activity toward cell wall polysaccharides. Phytochemistry 2008 0.80
30 Molecular modeling of the effects of mutant alleles on chalcone synthase protein structure. J Mol Model 2006 0.79
31 The future of academic anesthesia departments in Canada. Can J Anaesth 2006 0.78
32 A salt-bridge controlled by ligand binding modulates the hydrolysis reaction in a GH5 endoglucanase. Protein Eng Des Sel 2012 0.78
33 Steered molecular dynamics identifies critical residues of the Nodamura virus B2 suppressor of RNAi. J Mol Model 2014 0.78
34 Comparing atomistic molecular mechanics force fields for a difficult target: a case study on the Alzheimer's amyloid β-peptide. J Biomol Struct Dyn 2013 0.77
35 Molecular docking of inhibitors into monoamine oxidase B. Biochem Biophys Res Commun 2007 0.77
36 Probing the active site chemistry of β-glucosidases along the hydrolysis reaction pathway. Biochemistry 2012 0.77
37 Deletion of the N-terminal dirigent domain in maize beta-glucosidase aggregating factor and its homolog sorghum lectin dramatically alters the sugar-specificities of their lectin domains. Plant Physiol Biochem 2010 0.76
38 Steered molecular dynamics simulations reveal important mechanisms in reversible monoamine oxidase B inhibition. Biochemistry 2011 0.76
39 Aggregation of Alzheimer's amyloid β-peptide in biological membranes: a molecular dynamics study. Biochemistry 2013 0.76
40 Pharmacophore modeling improves virtual screening for novel peroxisome proliferator-activated receptor-gamma ligands. J Comput Aided Mol Des 2015 0.76
41 Homolog of the maize beta-glucosidase aggregating factor from sorghum is a jacalin-related GalNAc-specific lectin but lacks protein aggregating activity. Glycobiology 2008 0.75
42 Correlation between protein binding strength on immobilized metal affinity chromatography and the histidine-related protein surface structure. Anal Chem 2006 0.75
43 Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity. J Med Chem 2017 0.75
44 The family 1 glycoside hydrolase from Clostridium cellulolyticum H10 is a cellodextrin glucohydrolase. Appl Biochem Biotechnol 2009 0.75
45 Determination of beta-glucosidase aggregating factor (BGAF) binding and polymerization regions on the maize beta-glucosidase isozyme Glu1. Phytochemistry 2009 0.75
46 Lysine-81 and threonine-82 on maize beta-glucosidase isozyme Glu1 are the key amino acids involved in beta-glucosidase aggregating factor binding. Biochemistry 2009 0.75
47 Effects of protein microstructure on the retention time of T4 lysozyme variants in cation exchange chromatography. Anal Chem 2009 0.75
48 Quantifying protein microstructure and electrostatic effects on the change in Gibbs free energy of binding in immobilized metal affinity chromatography. Anal Chem 2008 0.75