Thomas S Otis

Author PubWeight™ 36.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion. Sci Transl Med 2013 2.89
2 Holographic photolysis of caged neurotransmitters. Nat Methods 2008 2.45
3 Photochemical control of endogenous ion channels and cellular excitability. Nat Methods 2008 2.30
4 Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activity. Nat Neurosci 2005 2.25
5 Submillisecond optical reporting of membrane potential in situ using a neuronal tracer dye. J Neurosci 2009 1.54
6 The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function. Genes Dev 2012 1.48
7 Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptors. J Neurophysiol 2011 1.40
8 Contributions of the GABAA receptor alpha6 subunit to phasic and tonic inhibition revealed by a naturally occurring polymorphism in the alpha6 gene. J Neurosci 2006 1.22
9 Ethanol acts directly on extrasynaptic subtypes of GABAA receptors to increase tonic inhibition. Alcohol 2007 1.21
10 Etomidate, propofol and the neurosteroid THDOC increase the GABA efficacy of recombinant alpha4beta3delta and alpha4beta3 GABA A receptors expressed in HEK cells. Neuropharmacology 2008 1.17
11 Climbing fiber activation of metabotropic glutamate receptors on cerebellar purkinje neurons. Neuron 2002 1.17
12 Effects of climbing fiber driven inhibition on Purkinje neuron spiking. J Neurosci 2012 1.15
13 A reorganized GABAergic circuit in a model of epilepsy: evidence from optogenetic labeling and stimulation of somatostatin interneurons. J Neurosci 2013 1.13
14 Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2. Hum Mol Genet 2012 1.05
15 Excitation of cerebellar interneurons by group I metabotropic glutamate receptors. J Neurophysiol 2004 0.97
16 Alcohol- and alcohol antagonist-sensitive human GABAA receptors: tracking δ subunit incorporation into functional receptors. Mol Pharmacol 2010 0.97
17 GABAA receptors increase excitability and conduction velocity of cerebellar parallel fiber axons. J Neurophysiol 2012 0.94
18 Persistent changes in spontaneous firing of Purkinje neurons triggered by the nitric oxide signaling cascade. J Neurosci 2003 0.92
19 Two-photon compatibility and single-voxel, single-trial detection of subthreshold neuronal activity by a two-component optical voltage sensor. PLoS One 2012 0.90
20 Isolation of glutamate transport-coupled charge flux and estimation of glutamate uptake at the climbing fiber-Purkinje cell synapse. Proc Natl Acad Sci U S A 2004 0.89
21 Prolonging the postcomplex spike pause speeds eyeblink conditioning. Proc Natl Acad Sci U S A 2012 0.88
22 Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue. Nat Commun 2012 0.86
23 An ultra small array of electrodes for stimulating multiple inputs into a single neuron. J Neurosci Methods 2004 0.85
24 Expression of GFP-tagged neuronal glutamate transporters in cerebellar Purkinje neurons. Neuropharmacology 2005 0.84
25 Blessed are the pacemakers. Nat Neurosci 2006 0.82
26 Glycine transporters not only take out the garbage, they recycle. Neuron 2003 0.80
27 A reinforcing circuit action of extrasynaptic GABAA receptor modulators on cerebellar granule cell inhibition. PLoS One 2013 0.78
28 Comments on "Ethanol sensitivity of GABAergic currents in cerebellar granule neurons is not increased by a single amino acid change (R100Q) in the alpha6 GABA(A) receptor subunit". J Pharmacol Exp Ther 2008 0.78
29 Whither withered Golgi? A retrospective evaluation of reticularist and synaptic constructs. Brain Res Bull 2007 0.77
30 Glia get excited. Nat Neurosci 2008 0.76
31 Repolarization matters: mutations in the Kv4.3 potassium channel cause SCA19/22. Ann Neurol 2012 0.75
32 Golgi in retrospect: a historiographic examination of contextual influence in tracing the constructs of neuronal organization. Brain Res Rev 2010 0.75