Published in Chem Biol on May 01, 2004
Synthesis-enabled functional group deletions reveal key underpinnings of amphotericin B ion channel and antifungal activities. Proc Natl Acad Sci U S A (2011) 1.11
Electronic tuning of site-selectivity. Nat Chem (2012) 1.09
Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity. Proc Natl Acad Sci U S A (2012) 1.03
Recent progress in the study of the interactions of amphotericin B with cholesterol and ergosterol in lipid environments. Eur Biophys J (2014) 0.91
Competitive binding of cholesterol and ergosterol to the polyene antibiotic nystatin. A fluorescence study. Biophys J (2006) 0.82
Single channel properties of lysenin measured in artificial lipid bilayers and their applications to biomolecule detection. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.76
Stereochemical Determination of Acyclic Structures Based on Carbon-Proton Spin-Coupling Constants. A Method of Configuration Analysis for Natural Products. J Org Chem (1999) 3.53
Vancomycin derivative with damaged D-Ala-D-Ala binding cleft binds to cross-linked peptidoglycan in the cell wall of Staphylococcus aureus. Biochemistry (2008) 1.53
Uncovering the protein translocon at the chloroplast inner envelope membrane. Science (2013) 1.50
GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus. Nat Cell Biol (2008) 1.33
A chemoattractant for ascidian spermatozoa is a sulfated steroid. Proc Natl Acad Sci U S A (2002) 1.13
Effects of lipid constituents on membrane-permeabilizing activity of amphidinols. Bioorg Med Chem (2007) 1.13
Recurrence of hypertrophic spinal pachymeningitis. Report of two cases and review of the literature. J Neurosurg Spine (2006) 1.12
Structures of new amphidinols with truncated polyhydroxyl chain and their membrane-permeabilizing activities. Bioorg Med Chem (2006) 1.11
Membrane-permeabilizing activities of amphidinol 3, polyene-polyhydroxy antifungal from a marine dinoflagellate. Biochim Biophys Acta (2004) 1.11
Combinatorial synthesis of the 1,5-polyol system based on cross metathesis: structure revision of amphidinol 3. Org Lett (2008) 1.10
Visualization of cargo concentration by COPII minimal machinery in a planar lipid membrane. EMBO J (2009) 1.07
Cloning of modular type I polyketide synthase genes from salinomycin producing strain of Streptomyces albus. Bioorg Med Chem (2003) 0.99
Structure of the trypanosome cyanide-insensitive alternative oxidase. Proc Natl Acad Sci U S A (2013) 0.99
Simultaneous optical and electrical recording of a single ion-channel. Jpn J Physiol (2002) 0.98
Total synthesis of the large non-ribosomal peptide polytheonamide B. Nat Chem (2010) 0.97
Automated parallel recordings of topologically identified single ion channels. Sci Rep (2013) 0.96
Mycosamine orientation of amphotericin B controlling interaction with ergosterol: sterol-dependent activity of conformation-restricted derivatives with an amino-carbonyl bridge. J Am Chem Soc (2005) 0.95
Interaction between the marine sponge cyclic peptide theonellamide A and sterols in lipid bilayers as viewed by surface plasmon resonance and solid-state (2)H nuclear magnetic resonance. Biochemistry (2013) 0.94
Three-dimensional Motion Analysis of the Ankle during Backward Walking. J Phys Ther Sci (2013) 0.93
Amphotericin B covalent dimers forming sterol-dependent ion-permeable membrane channels. J Am Chem Soc (2002) 0.92
Role of the KcsA channel cytoplasmic domain in pH-dependent gating. Biophys J (2011) 0.92
Comprehensive molecular motion capture for sphingomyelin by site-specific deuterium labeling. Biochemistry (2012) 0.91
Molecular depth profiling of multilayer structures of organic semiconductor materials by secondary ion mass spectrometry with large argon cluster ion beams. Rapid Commun Mass Spectrom (2009) 0.90
Rearrangements in the KcsA cytoplasmic domain underlie its gating. J Biol Chem (2009) 0.90
Precise and fast secondary ion mass spectrometry depth profiling of polymer materials with large Ar cluster ion beams. Rapid Commun Mass Spectrom (2009) 0.89
Water-mediated recognition of simple alkyl chains by heart-type fatty-acid-binding protein. Angew Chem Int Ed Engl (2014) 0.88
Direct interaction between amphotericin B and ergosterol in lipid bilayers as revealed by 2H NMR spectroscopy. J Am Chem Soc (2009) 0.88
Structure of membrane-bound amphidinol 3 in isotropic small bicelles. Org Lett (2008) 0.87
Large molecular assembly of amphotericin B formed in ergosterol-containing membrane evidenced by solid-state NMR of intramolecular bridged derivative. J Am Chem Soc (2006) 0.87
Cy3-3-acylcholine: a fluorescent analogue of acetylcholine for single molecule detection. Bioorg Med Chem Lett (2007) 0.86
Lysenin forms a voltage-dependent channel in artificial lipid bilayer membranes. Biochem Biophys Res Commun (2006) 0.84
NMR-based conformational analysis of sphingomyelin in bicelles. Bioorg Med Chem (2011) 0.84
3D structures of membrane-associated small molecules as determined in isotropic bicelles. Nat Prod Rep (2010) 0.84
Conformation and location of membrane-bound salinomycin-sodium complex deduced from NMR in isotropic bicelles. J Am Chem Soc (2007) 0.84
Immobilizing single lipid and channel molecules in artificial lipid bilayers with annexin A5. Langmuir (2006) 0.84
Conformation and position of membrane-bound amphotericin B deduced from NMR in SDS micelles. J Org Chem (2007) 0.83
Stereoselective synthesis of the C31-C40/C43-C52 unit of amphidinol 3. J Org Chem (2009) 0.83
Self-assembled amphotericin B is probably surrounded by ergosterol: bimolecular interactions as evidenced by solid-state NMR and CD spectra. Chemistry (2008) 0.83
Detailed description of the conformation and location of membrane-bound erythromycin a using isotropic bicelles. J Med Chem (2006) 0.83
Cholesterol markedly reduces ion permeability induced by membrane-bound amphotericin B. Biochim Biophys Acta (2002) 0.83
Direct and stereospecific interaction of amphidinol 3 with sterol in lipid bilayers. Biochemistry (2014) 0.82
Complex formation of amphotericin B in sterol-containing membranes as evidenced by surface plasmon resonance. Biochemistry (2008) 0.82
Membrane interaction of amphotericin B as single-length assembly examined by solid state NMR for uniformly 13C-enriched agent. Bioorg Med Chem (2006) 0.82
Dominant formation of a single-length channel by amphotericin B in dimyristoylphosphatidylcholine membrane evidenced by 13C-31P rotational echo double resonance. Biochemistry (2005) 0.82
Crystallization and preliminary crystallographic analysis of cyanide-insensitive alternative oxidase from Trypanosoma brucei brucei. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.81
Synthesis and structure revision of the C43-C67 part of amphidinol 3. Org Lett (2013) 0.81
Orientation of fluorinated cholesterol in lipid bilayers analyzed by 19F tensor calculation and solid-state NMR. J Am Chem Soc (2008) 0.81
Head-to-tail interaction between amphotericin B and ergosterol occurs in hydrated phospholipid membrane. Biochemistry (2011) 0.81
Sterol effect on interaction between amphidinol 3 and liposomal membrane as evidenced by surface plasmon resonance. Bioorg Med Chem Lett (2010) 0.81
Selective modification of the N-terminal structure of polytheonamide B significantly changes its cytotoxicity and activity as an ion channel. ChemMedChem (2012) 0.81
Design and synthesis of ladder-shaped tetracyclic, heptacyclic, and decacyclic ethers and evaluation of the interaction with transmembrane proteins. J Am Chem Soc (2008) 0.80
The twisted side chain of antillatoxin is important for potent toxicity: total synthesis and biological evaluation of antillatoxin and analogues. Angew Chem Int Ed Engl (2010) 0.80
Membrane permeabilizing activity of amphotericin B is affected by chain length of phosphatidylcholine added as minor constituent. Biochim Biophys Acta (2003) 0.80
Design, synthesis, and biological evaluation of fluorinated analogues of salicylihalamide. J Med Chem (2009) 0.80
Convergent synthesis and biological activity of the WXYZA'B'C' ring system of maitotoxin. Org Lett (2008) 0.80
Design and synthesis of an artificial ladder-shaped polyether that interacts with glycophorin A. Bioorg Med Chem Lett (2006) 0.80
Glycoglycerolipid from the membranes of Acholeplasma laidlawii binds to human immunodeficiency virus-1 (HIV-1) and accelerates its entry into cells. Curr Microbiol (2004) 0.79
Variability in C(3)-plant cell-wall biosynthesis in a high-CO(2) atmosphere by solid-state NMR spectroscopy. J Am Chem Soc (2010) 0.79
Conformational change of spermidine upon interaction with adenosine triphosphate in aqueous solution. Chemistry (2009) 0.79
Direct manipulation of a single potassium channel gate with an atomic force microscope probe. Small (2011) 0.79
Channels formed by amphotericin B covalent dimers exhibit rectification. J Membr Biol (2011) 0.79
Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase. Mol Microbiol (2014) 0.79
Amphotericin B covalent dimers bearing a tartarate linkage. Chem Biodivers (2004) 0.79
X-ray crystallographic and biochemical characterization of the inhibitory action of an imidazole-dioxolane compound on heme oxygenase. Biochemistry (2007) 0.79
Ergosterol increases the intermolecular distance of amphotericin B in the membrane-bound assembly as evidenced by solid-state NMR. Biochemistry (2008) 0.78
Design, synthesis and functional analysis of dansylated polytheonamide mimic: an artificial peptide ion channel. J Am Chem Soc (2012) 0.78
Amphotericin B-induced ion flux is markedly attenuated in phosphatidylglycerol membrane as evidenced by a newly devised fluorometric method. Bioorg Med Chem (2009) 0.78
Detection of Rap1A as a yessotoxin binding protein from blood cell membranes. Bioorg Med Chem Lett (2010) 0.78
Roles of integral protein in membrane permeabilization by amphidinols. Biochim Biophys Acta (2008) 0.78
Prorocentrol, a polyoxy linear carbon chain compound isolated from the toxic dinoflagellate Prorocentrum hoffmannianum. J Org Chem (2011) 0.78