PubRank

Martin Widschwendter

Author PubWeight™ 95.94‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006 13.63
2 Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Res 2010 6.03
3 Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature 2010 4.01
4 A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nat Genet 2010 3.86
5 FBXW7/hCDC4 is a general tumor suppressor in human cancer. Cancer Res 2007 3.79
6 An epigenetic signature in peripheral blood predicts active ovarian cancer. PLoS One 2009 3.33
7 Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies. Bioinformatics 2011 2.91
8 hCDC4 gene mutations in endometrial cancer. Cancer Res 2002 2.36
9 DNA methylation in serum of breast cancer patients: an independent prognostic marker. Cancer Res 2003 2.14
10 Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer. Cancer Res 2006 1.99
11 Methylation changes in faecal DNA: a marker for colorectal cancer screening? Lancet 2004 1.80
12 Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip. Methods 2010 1.71
13 Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation. Genome Med 2012 1.65
14 Circulating tumor-specific DNA: a marker for monitoring efficacy of adjuvant therapy in cancer patients. Cancer Res 2005 1.62
15 Hypomethylation and hypermethylation of DNA in Wilms tumors. Oncogene 2002 1.59
16 DNA hypomethylation is prevalent even in low-grade breast cancers. Cancer Biol Ther 2004 1.53
17 Differential variability improves the identification of cancer risk markers in DNA methylation studies profiling precursor cancer lesions. Bioinformatics 2012 1.51
18 Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer. Cancer Res 2004 1.45
19 HOXA11 DNA methylation--a novel prognostic biomarker in ovarian cancer. Int J Cancer 2008 1.44
20 The dynamics and prognostic potential of DNA methylation changes at stem cell gene loci in women's cancer. PLoS Genet 2012 1.33
21 A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform. BMC Bioinformatics 2012 1.26
22 Recruitment of newly diagnosed ovarian cancer patients proved challenging in a multicentre biobanking study. J Clin Epidemiol 2010 1.18
23 Cellular network entropy as the energy potential in Waddington's differentiation landscape. Sci Rep 2013 1.12
24 Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins. Proc Natl Acad Sci U S A 2011 1.11
25 Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development. PLoS Med 2013 1.10
26 DNA methylation in serum and tumors of cervical cancer patients. Clin Cancer Res 2004 1.06
27 Prognostic DNA methylation marker in serum of cancer patients. Ann N Y Acad Sci 2004 1.06
28 Methylation status and expression of human telomerase reverse transcriptase in ovarian and cervical cancer. Gynecol Oncol 2004 1.06
29 Methylated DNA as a possible screening marker for neoplastic disease in several body fluids. Expert Rev Mol Diagn 2003 1.06
30 DNA methylation analysis in liquid-based cytology for cervical cancer screening. Int J Cancer 2009 1.04
31 Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer. Breast Cancer Res 2010 1.01
32 Underlying mechanisms of ovarian cancer risk reduction after tubal ligation. Acta Obstet Gynecol Scand 2011 0.99
33 Methylated DNA collected by tampons--a new tool to detect endometrial cancer. Cancer Epidemiol Biomarkers Prev 2004 0.99
34 Cyclin E dysregulation and chromosomal instability in endometrial cancer. Oncogene 2004 0.99
35 CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer. EMBO Mol Med 2013 0.99
36 Analysis of methylated genes in peritoneal fluids of ovarian cancer patients: a new prognostic tool. Clin Chem 2004 0.98
37 Analysis of aberrant DNA methylation and human papillomavirus DNA in cervicovaginal specimens to detect invasive cervical cancer and its precursors. Clin Cancer Res 2004 0.96
38 Loss of imprinting and aberrant methylation of IGF2 in placentas from pregnancies complicated with fetal growth restriction. Int J Mol Med 2011 0.96
39 CDH1 and CDH13 methylation in serum is an independent prognostic marker in cervical cancer patients. Int J Cancer 2004 0.95
40 Distinctive topology of age-associated epigenetic drift in the human interactome. Proc Natl Acad Sci U S A 2013 0.94
41 Toll-like receptor 9 expression in breast and ovarian cancer is associated with poorly differentiated tumors. Cancer Sci 2010 0.92
42 Detection of low molecular weight derivatives of cyclin E1 is a function of cyclin E1 protein levels in breast cancer. Cancer Res 2006 0.92
43 DNA methylation changes in sera of women in early pregnancy are similar to those in advanced breast cancer patients. Clin Chem 2004 0.91
44 Corruption of the intra-gene DNA methylation architecture is a hallmark of cancer. PLoS One 2013 0.88
45 Methylated NEUROD1 promoter is a marker for chemosensitivity in breast cancer. Clin Cancer Res 2008 0.87
46 DNA methylation markers for early detection of women's cancer: promise and challenges. Epigenomics 2014 0.87
47 Genome-scale screen for DNA methylation-based detection markers for ovarian cancer. PLoS One 2011 0.87
48 Association of serum sex steroid receptor bioactivity and sex steroid hormones with breast cancer risk in postmenopausal women. Endocr Relat Cancer 2012 0.87
49 A DNA methylation pattern similar to normal tissue is associated with better prognosis in human cervical cancer. Cancer Lett 2004 0.85
50 Pregnancy-associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer. J Pathol 2014 0.84
51 GALR1 methylation in vaginal swabs is highly accurate in identifying women with endometrial cancer. Int J Gynecol Cancer 2013 0.84
52 A prospective validation of the IOTA logistic regression models (LR1 and LR2) in comparison to subjective pattern recognition for the diagnosis of ovarian cancer. Int J Gynecol Cancer 2013 0.83
53 Development and validation of a method for profiling post-translational modification activities using protein microarrays. PLoS One 2010 0.83
54 DNA methylation of polycomb group target genes in cores taken from breast cancer centre and periphery. Breast Cancer Res Treat 2009 0.82
55 Emerging promise of epigenetics and DNA methylation for the diagnosis and management of women's cancers. Epigenomics 2010 0.82
56 Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene. Oncotarget 2014 0.82
57 Noninvasive nutritional management of ovarian cancer patients: beyond intestinal obstruction. Int J Gynecol Cancer 2012 0.80
58 Pregnancy as a tissue expander in the correction of a scar deformity. Am J Obstet Gynecol 2004 0.80
59 A randomised controlled trial comparing surgical intervention rates between two protocols for the management of asymptomatic adnexal tumours in postmenopausal women. BMJ Open 2012 0.79
60 PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer. Cancer Res 2014 0.78
61 5-methylcytosine--the fifth base of DNA: the fifth wheel on a car or a highly promising diagnostic and therapeutic target in cancer? Dis Markers 2007 0.76
62 Fooled by the film: delayed diagnosis of incarcerated small-bowel hernia after laparoscopic surgery for endometrial cancer. Int J Gynecol Cancer 2012 0.75
63 Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer. Oncology 2016 0.75