Published in Gene Ther on July 01, 2004
The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance. Biomaterials (2009) 1.37
Combination of siRNA-directed Gene Silencing With Cisplatin Reverses Drug Resistance in Human Non-small Cell Lung Cancer. Mol Ther Nucleic Acids (2013) 1.03
Biophysics of cell membrane lipids in cancer drug resistance: Implications for drug transport and drug delivery with nanoparticles. Adv Drug Deliv Rev (2013) 0.90
Personalized cancer approach: using RNA interference technology. World J Surg (2011) 0.83
Reversal of multi-drug resistance by pSUPER-shRNA-mdr1 in vivo and in vitro. World J Gastroenterol (2009) 0.83
Reversing multidrug resistance by RNA interference through the suppression of MDR1 gene in human hepatoma cells. World J Gastroenterol (2006) 0.81
Role of the highly structured 5'-end region of MDR1 mRNA in P-glycoprotein expression. Biochem J (2007) 0.79
Repetitive extragenic palindromic sequences: a major component of the bacterial genome. Cell (1984) 6.45
Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport. Nature (1990) 6.41
A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria. Nature (1986) 5.77
ERIC sequences: a novel family of repetitive elements in the genomes of Escherichia coli, Salmonella typhimurium and other enterobacteria. Mol Microbiol (1991) 4.93
A DEAD-box RNA helicase in the Escherichia coli RNA degradosome. Nature (1996) 4.83
Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. typhimurium. Nature (1982) 4.71
A novel intercistronic regulatory element of prokaryotic operons. Nature (1982) 4.58
Mechanisms of mRNA decay in bacteria: a perspective. Gene (1988) 4.28
Stabilization of translationally active mRNA by prokaryotic REP sequences. Cell (1987) 4.08
The oligopeptide transport system of Bacillus subtilis plays a role in the initiation of sporulation. Mol Microbiol (1991) 3.93
The Escherichia coli ATP-binding cassette (ABC) proteins. Mol Microbiol (1998) 3.77
Osmoregulation of gene expression in Salmonella typhimurium: proU encodes an osmotically induced betaine transport system. J Bacteriol (1985) 3.67
Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria. Cell (1990) 3.39
The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression. Cell (1992) 3.00
Characterization of porin and ompR mutants of a virulent strain of Salmonella typhimurium: ompR mutants are attenuated in vivo. Infect Immun (1989) 3.00
Molecular characterization of the oligopeptide permease of Salmonella typhimurium. J Mol Biol (1987) 3.00
Salmonella typhimurium proP gene encodes a transport system for the osmoprotectant betaine. J Bacteriol (1985) 2.97
Immunocytochemical localization of the cystic fibrosis gene product CFTR. Proc Natl Acad Sci U S A (1991) 2.82
Differential mRNA stability controls relative gene expression within a polycistronic operon. Cell (1987) 2.79
RNase E, an endoribonuclease, has a general role in the chemical decay of Escherichia coli mRNA: evidence that rne and ams are the same genetic locus. Mol Microbiol (1990) 2.73
Osmotic regulation of transcription: induction of the proU betaine transport gene is dependent on accumulation of intracellular potassium. J Bacteriol (1986) 2.71
DNA supercoiling and environmental regulation of virulence gene expression in Shigella flexneri. Nature (1990) 2.67
Peptide chemotaxis in E. coli involves the Tap signal transducer and the dipeptide permease. Nature (1986) 2.66
Ribonuclease E organizes the protein interactions in the Escherichia coli RNA degradosome. Genes Dev (1998) 2.60
DNA supercoiling and the anaerobic and growth phase regulation of tonB gene expression. J Bacteriol (1988) 2.54
Nucleotide binding by membrane components of bacterial periplasmic binding protein-dependent transport systems. EMBO J (1985) 2.49
Anaerobic and leucine-dependent expression of a peptide transport gene in Salmonella typhimurium. J Bacteriol (1984) 2.46
A protein complex mediating mRNA degradation in Escherichia coli. Mol Microbiol (1994) 2.39
Two periplasmic transport proteins which interact with a common membrane receptor show extensive homology: complete nucleotide sequences. Proc Natl Acad Sci U S A (1981) 2.37
Fimbrial phase variation in Escherichia coli: dependence on integration host factor and homologies with other site-specific recombinases. J Bacteriol (1987) 2.36
The chromatin-associated protein H-NS alters DNA topology in vitro. EMBO J (1994) 2.33
Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein. Nature (1992) 2.31
Uptake of cell wall peptides by Salmonella typhimurium and Escherichia coli. J Bacteriol (1987) 2.18
Peptide transport and chemotaxis in Escherichia coli and Salmonella typhimurium: characterization of the dipeptide permease (Dpp) and the dipeptide-binding protein. Mol Microbiol (1991) 2.09
Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein. Cell (1992) 2.09
A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene. Nature (1998) 2.05
The structural basis of sequence-independent peptide binding by OppA protein. Science (1994) 2.05
mRNA degradation by processive 3'-5' exoribonucleases in vitro and the implications for prokaryotic mRNA decay in vivo. J Mol Biol (1991) 1.93
An overlap between osmotic and anaerobic stress responses: a potential role for DNA supercoiling in the coordinate regulation of gene expression. Mol Microbiol (1989) 1.93
Two genetically distinct pathways for transcriptional regulation of anaerobic gene expression in Salmonella typhimurium. J Bacteriol (1986) 1.88
Communication between multiple drug binding sites on P-glycoprotein. Mol Pharmacol (2000) 1.87
A family of closely related ATP-binding subunits from prokaryotic and eukaryotic cells. Bioessays (1988) 1.84
The genetic control of DNA supercoiling in Salmonella typhimurium. EMBO J (1984) 1.83
OmpR and EnvZ are pleiotropic regulatory proteins: positive regulation of the tripeptide permease (tppB) of Salmonella typhimurium. Mol Gen Genet (1987) 1.81
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Nature (1993) 1.79
Proline uptake through the major transport system of Salmonella typhimurium is coupled to sodium ions. J Bacteriol (1984) 1.76
TonB protein of Salmonella typhimurium. A model for signal transduction between membranes. J Mol Biol (1990) 1.76
The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. EMBO J (2000) 1.76
Periplasmic protein associated with the oligopeptide permeases of Salmonella typhimurium and Escherichia coli. J Bacteriol (1983) 1.75
Polyadenylation promotes degradation of 3'-structured RNA by the Escherichia coli mRNA degradosome in vitro. J Biol Chem (1999) 1.74
Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1alpha promoter. Gene Ther (2001) 1.72
Expression and mutational analysis of the nucleoid-associated protein H-NS of Salmonella typhimurium. Mol Microbiol (1992) 1.71
Molecular characterization of the proU loci of Salmonella typhimurium and Escherichia coli encoding osmoregulated glycine betaine transport systems. Mol Microbiol (1989) 1.67
Regulatory regions of two transport operons under nitrogen control: nucleotide sequences. Proc Natl Acad Sci U S A (1982) 1.66
Characterization and physiological roles of membrane-bound hydrogenase isoenzymes from Salmonella typhimurium. J Bacteriol (1986) 1.62
Polyphosphate kinase is a component of the Escherichia coli RNA degradosome. Mol Microbiol (1997) 1.60
Genetic characterization and molecular cloning of the tripeptide permease (tpp) genes of Salmonella typhimurium. J Bacteriol (1984) 1.59
Genetic map of the opp (Oligopeptide permease) locus of Salmonella typhimurium. J Bacteriol (1983) 1.58
Osmotic regulation of porin expression: a role for DNA supercoiling. Mol Microbiol (1989) 1.57
Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis. J Biol Chem (1997) 1.57
The chromatin-associated protein H-NS. Biochimie (1994) 1.56
Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle. EMBO J (2001) 1.54
Oligomerization of the chromatin-structuring protein H-NS. Mol Microbiol (2000) 1.50
Volume-activated chloride channels in HeLa cells are blocked by verapamil and dideoxyforskolin. Pflugers Arch (1993) 1.48
Peptide transport in bacteria. Methods Enzymol (1986) 1.47
Genetic organization of the oligopeptide permease (opp) locus of Salmonella typhimurium and Escherichia coli. J Bacteriol (1983) 1.47
DNA supercoiling in Escherichia coli: topA mutations can be suppressed by DNA amplifications involving the tolC locus. Mol Microbiol (1989) 1.47
Enteric bacteria and osmotic stress: intracellular potassium glutamate as a secondary signal of osmotic stress? FEMS Microbiol Rev (1990) 1.41
Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. Hum Mol Genet (2000) 1.39
Extensive homology between membrane-associated components of histidine and maltose transport systems of Salmonella typhimurium and Escherichia coli. J Biol Chem (1982) 1.39
Regulation of compatible solute accumulation in Salmonella typhimurium: evidence for a glycine betaine efflux system. J Gen Microbiol (1991) 1.39
Structure and function of X-Pro dipeptide repeats in the TonB proteins of Salmonella typhimurium and Escherichia coli. J Mol Biol (1990) 1.36
Sequence-imposed structural constraints in the TonB protein of E. coli. FEBS Lett (1986) 1.36
Effects of anaerobic regulatory mutations and catabolite repression on regulation of hydrogen metabolism and hydrogenase isoenzyme composition in Salmonella typhimurium. J Bacteriol (1986) 1.35
Lateral diffusion of proteins in the periplasm of Escherichia coli. J Bacteriol (1986) 1.34
A sequence-specific function for the N-terminal signal-like sequence of the TonB protein. Mol Microbiol (1993) 1.34
DNA binding is not sufficient for H-NS-mediated repression of proU expression. J Biol Chem (1997) 1.30
Protein kinase C-mediated phosphorylation of the human multidrug resistance P-glycoprotein regulates cell volume-activated chloride channels. EMBO J (1995) 1.30
The functional purification of P-glycoprotein is dependent on maintenance of a lipid-protein interface. Biochim Biophys Acta (1997) 1.29
Energy coupling to periplasmic binding protein-dependent transport systems: stoichiometry of ATP hydrolysis during transport in vivo. Proc Natl Acad Sci U S A (1989) 1.29
The crystal structures of the oligopeptide-binding protein OppA complexed with tripeptide and tetrapeptide ligands. Structure (1995) 1.28
Tamoxifen blocks chloride channels. A possible mechanism for cataract formation. J Clin Invest (1994) 1.26
Peptide uptake by Salmonella typhimurium. The periplasmic oligopeptide-binding protein. Eur J Biochem (1986) 1.26
Peptide transport in Salmonella typhimurium: molecular cloning and characterization of the oligopeptide permease genes. Mol Gen Genet (1987) 1.25
Scanning surface confocal microscopy for simultaneous topographical and fluorescence imaging: application to single virus-like particle entry into a cell. Proc Natl Acad Sci U S A (2002) 1.24
The nucleoid-associated protein StpA binds curved DNA, has a greater DNA-binding affinity than H-NS and is present in significant levels in hns mutants. Biochimie (2001) 1.23
ExbB acts as a chaperone-like protein to stabilize TonB in the cytoplasm. Mol Microbiol (1993) 1.22
Escherichia coli endoribonuclease RNase E: autoregulation of expression and site-specific cleavage of mRNA. Mol Microbiol (1993) 1.19
mRNA degradation in Escherichia coli: a novel factor which impedes the exoribonucleolytic activity of PNPase at stem-loop structures. Mol Microbiol (1994) 1.17
Na+-induced transcription of nhaA, which encodes an Na+/H+ antiporter in Escherichia coli, is positively regulated by nhaR and affected by hns. J Bacteriol (1996) 1.17
Physical map of the Salmonella typhimurium histidine transport operon: correlation with the genetic map. J Bacteriol (1981) 1.16
Role of hns in the virulence phenotype of pathogenic salmonellae. Mol Microbiol (1994) 1.15
Use of transcriptional fusions to monitor gene expression: a cautionary tale. J Bacteriol (1994) 1.13
Identification and localization of the membrane-associated, ATP-binding subunit of the oligopeptide permease of Salmonella typhimurium. Eur J Biochem (1989) 1.12
Membrane topology of the integral membrane components, OppB and OppC, of the oligopeptide permease of Salmonella typhimurium. Mol Microbiol (1992) 1.11
A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther (1997) 1.11
Isolation and characterization of lac fusions to two nitrogen-regulated promoters. Mol Gen Genet (1984) 1.11
ABCA1 expression in carotid atherosclerotic plaques. Stroke (2004) 1.10
Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis. Gene Ther (2000) 1.10
DNA twist, flexibility and transcription of the osmoregulated proU promoter of Salmonella typhimurium. EMBO J (1995) 1.08