PubRank

T Wirth

Author PubWeight™ 107.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature 1986 8.64
2 An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity. Nature 1987 4.11
3 NF-kappaB is activated and promotes cell death in focal cerebral ischemia. Nat Med 1999 2.96
4 High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors. EMBO J 1995 2.48
5 Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. Gut 2008 2.36
6 Distinct NF-kappa B/Rel transcription factors are responsible for tissue-specific and inducible gene activation. Nature 1993 2.28
7 A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus. Nat Genet 1996 2.16
8 Inducible expression and phosphorylation of coactivator BOB.1/OBF.1 in T cells. Science 1997 1.93
9 Activation of NF-kappa B via the Ikappa B kinase complex is both essential and sufficient for proinflammatory gene expression in primary endothelial cells. J Biol Chem 2001 1.92
10 Hodgkin and reed-sternberg cells represent an expansion of a single clone originating from a germinal center B-cell with functional immunoglobulin gene rearrangements but defective immunoglobulin transcription. Blood 2000 1.79
11 Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta. Gastroenterology 2000 1.56
12 Family of middle repetitive DNA sequences in the mouse genome with structural features of solitary retroviral long terminal repeats. Proc Natl Acad Sci U S A 1983 1.54
13 [Colonic stenting: an opportunity with a risk : A critical evaluation]. Chirurg 2015 1.38
14 Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation. Proc Natl Acad Sci U S A 2000 1.36
15 Oct2 transactivation from a remote enhancer position requires a B-cell-restricted activity. Mol Cell Biol 1992 1.35
16 Tumour necrosis factor related apoptosis inducing ligand (TRAIL) induces hepatic steatosis in viral hepatitis and after alcohol intake. Gut 2005 1.34
17 Structure and genomic organization of a new family of murine retrovirus-related DNA sequences (MuRRS). Nucleic Acids Res 1985 1.33
18 Two distinct mechanisms contribute to the constitutive activation of RelB in lymphoid cells. EMBO J 1994 1.30
19 Regulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1. J Biol Chem 1999 1.27
20 Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells. Blood 1998 1.25
21 Induction of pre-B cell proliferation after de novo synthesis of the pre-B cell receptor. Proc Natl Acad Sci U S A 2001 1.24
22 Regulation of BOB.1/OBF.1 stability by SIAH. EMBO J 2001 1.23
23 Transforming growth factor beta and cyclosporin A inhibit the inducible activity of the interleukin-2 gene in T cells through a noncanonical octamer-binding site. Mol Cell Biol 1993 1.19
24 Down-regulation of BOB.1/OBF.1 and Oct2 in classical Hodgkin disease but not in lymphocyte predominant Hodgkin disease correlates with immunoglobulin transcription. Blood 2001 1.15
25 The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP. Nucleic Acids Res 1994 1.13
26 Functional characterization of the murine homolog of the B cell-specific coactivator BOB.1/OBF.1. J Biol Chem 1995 1.10
27 Identification of CD36 as the first gene dependent on the B-cell differentiation factor Oct-2. Genes Dev 1995 1.06
28 Controlled ribozyme targeting demonstrates an antiapoptotic effect of carcinoembryonic antigen in HT29 colon cancer cells. Clin Cancer Res 2001 1.05
29 Evidence for mobility of a new family of mouse middle repetitive DNA elements (LTR-IS). Nucleic Acids Res 1984 1.03
30 Early age of onset in fatal familial insomnia. Two novel cases and review of the literature. J Neurol 2004 1.02
31 Lymphoid- and myeloid-specific activity of the PU.1 promoter is determined by the combinatorial action of octamer and ets transcription factors. Oncogene 1995 1.02
32 A strategy for efficient in vitro translation of cDNAs using the rabbit beta-globin leader sequence. Nucleic Acids Res 1991 1.01
33 CD40, but not lipopolysaccharide and anti-IgM stimulation of primary B lymphocytes, leads to a persistent nuclear accumulation of RelB. J Immunol 1996 1.01
34 Mitochondrial differentiation in a polymorphic land snail: evidence for Pleistocene survival within the boundaries of permafrost. J Evol Biol 2003 1.01
35 Up-regulation of BOB.1/OBF.1 expression in normal germinal center B cells and germinal center-derived lymphomas. Am J Pathol 2000 1.01
36 Truncated vesicular stomatitis virus G protein improves baculovirus transduction efficiency in vitro and in vivo. Gene Ther 2006 1.00
37 Model for estimating enteric methane emissions from United States dairy and feedlot cattle. J Anim Sci 2008 1.00
38 Failures and complications in intramedullary nailing of children's forearm fractures. J Child Orthop 2010 0.99
39 The B lymphocyte-specific coactivator BOB.1/OBF.1 is required at multiple stages of B-cell development. Mol Cell Biol 2001 0.98
40 Treatment of severely displaced proximal humeral fractures in children with retrograde elastic stable intramedullary nailing. Injury 2008 0.98
41 Evidence that a major class of mouse endogenous long terminal repeats (LTRs) resulted from recombination between exogenous retroviral LTRs and similar LTR-like elements (LTR-IS). Proc Natl Acad Sci U S A 1984 0.97
42 The BOB.1 / OBF.1 co-activator is essential for octamer-dependent transcription in B cells. Eur J Immunol 2000 0.96
43 NF-kappaB transcription factors: critical regulators of hematopoiesis and neuronal survival. Cytokine Growth Factor Rev 2000 0.96
44 Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo. Gene Ther 2003 0.96
45 [Treatment of congenital clubfoot with the Ponseti method]. Z Orthop Ihre Grenzgeb 2006 0.95
46 Differential transactivation potential of Oct1 and Oct2 is determined by additional B cell-specific activities. EMBO J 1994 0.95
47 CRISP-3, a protein with homology to plant defense proteins, is expressed in mouse B cells under the control of Oct2. Mol Cell Biol 1996 0.93
48 Gene therapy: the first approved gene-based medicines, molecular mechanisms and clinical indications. Curr Mol Pharmacol 2008 0.92
49 Novel twelve-generation kindred of fatal familial insomnia from germany representing the entire spectrum of disease expression. Am J Med Genet 1999 0.92
50 Bruton's Tyrosine Kinase is involved in innate and adaptive immunity. Histol Histopathol 2005 0.91
51 Analysis of transcriptional stimulation by recombinant Oct proteins in a cell-free system. J Biol Chem 1993 0.90
52 Magnetic resonance imaging of viral particle biodistribution in vivo. Gene Ther 2006 0.89
53 Functional differences between the Oct2 transactivation domains determine the transactivation potential of individual Oct2 isoforms. Nucleic Acids Res 1994 0.89
54 Induction of nuclear factor-kappa B during primary B cell differentiation. J Immunol 1998 0.87
55 Functional analysis of defined mutations in the immunoglobulin heavy-chain enhancer in transgenic mice. Nucleic Acids Res 1992 0.86
56 Isolation and characterization of microsatellite loci in the yellow perch (Perca flavescens), and cross- species amplification within the family Percidae. Mol Ecol 2000 0.85
57 Requirement of NEMO/IKKγ for effective expansion of KRAS-induced precancerous lesions in the pancreas. Oncogene 2012 0.85
58 VSV virotherapy improves chemotherapy by triggering apoptosis due to proteasomal degradation of Mcl-1. Gene Ther 2009 0.84
59 [Treatment of vertical talus with the Dobbs method]. Z Orthop Unfall 2011 0.83
60 Defective octamer-dependent transcription is responsible for silenced immunoglobulin transcription in Reed-Sternberg cells. Blood 2001 0.83
61 Arthroscopic reduction of the dislocated hip in infants. J Bone Joint Surg Br 2012 0.83
62 Anti-IgM antibodies down modulate mu-enhancer activity and OTF2 levels in LPS-stimulated mouse splenic B-cells. Nucleic Acids Res 1991 0.82
63 [Wound secretions in standard orthopedic surgery interventions using a new kind of closed vacuum drainage. A report of experiences]. Unfallchirurg 1991 0.82
64 The zinc-finger protein KCMF1 is overexpressed during pancreatic cancer development and downregulation of KCMF1 inhibits pancreatic cancer development in mice. Oncogene 2010 0.81
65 Increased invasion of malignant gliomas after 15-LO-1 and HSV-tk/ganciclovir combination gene therapy. Cancer Gene Ther 2012 0.80
66 No change of brain extracellular catecholamine levels after acute catechol-O-methyltransferase inhibition: a microdialysis study in anaesthetized rats. Eur J Pharmacol 1998 0.80
67 The influence of intermittent external dynamic pressure and tension forces on the healing of an epiphyseal fracture. Arch Orthop Trauma Surg 2001 0.80
68 Targeting of biotinylated compounds to its target tissue using a low-density lipoprotein receptor-avidin fusion protein. Gene Ther 2003 0.80
69 Glutamate-dependent activation of NF-kappaB during mouse cerebellum development. J Neurosci 1997 0.80
70 Identification of target genes of the lymphoid-specific transcription factor Oct2. Immunobiology 1997 0.79
71 [Diagnosis and therapy of coxitis fugax with special reference to the value of ultrasonographY-assisted diagnosis and hip joint puncture]. Z Orthop Ihre Grenzgeb 1993 0.79
72 Demethylation and the establishment of kappa allelic exclusion. Cold Spring Harb Symp Quant Biol 1999 0.79
73 [Mid-term results of idiopathic clubfeet treated with the Ponseti method]. Z Orthop Unfall 2012 0.79
74 Assessment of the treatment costs of extracorporeal shock wave therapy versus surgical treatment for shoulder diseases. Int J Technol Assess Health Care 2001 0.79
75 Novel polymer-bound chiral selenium electrophiles. Org Lett 2001 0.79
76 RelB is a key player for both kappa B-dependent transcription and demethylation in B cells. Immunobiology 1997 0.79
77 In vivo manipulation of interleukin-2 expression by a retroviral tetracycline (tet)-regulated system. Cancer Gene Ther 1999 0.78
78 [Predicting the outcome of diskectomy.]. Schmerz 1991 0.78
79 Genetic signatures in an invasive parasite of Anguilla anguilla correlate with differential stock management. J Fish Biol 2010 0.78
80 Molecular genetics of the germinal center reaction. J Cell Physiol 1998 0.78
81 The mutant plasmacytoma cell line S107 allows the identification of distinct pathways leading to NF-kappaB activation. J Biol Chem 1998 0.77
82 Analysis of promoter activity by polymerase chain reaction amplification of reporter gene mRNA. Anal Biochem 1996 0.77
83 ABF-1 is frequently silenced by promoter methylation in follicular lymphoma, diffuse large B-cell lymphoma and Burkitt's lymphoma. Leukemia 2008 0.77
84 Isolation and characterization of 12 dinucleotide microsatellites in the European eel, Anguilla anguilla L., and tests of amplification in other species of eels. Mol Ecol Resour 2008 0.77
85 Controversies in childhood osteosarcoma. Minerva Pediatr 2013 0.76
86 [Is conservative treatment of partial or complete anterior cruciate ligament rupture still justified? An analysis of the recent literature and a recommendation for arriving at a decision]. Z Orthop Ihre Grenzgeb 1992 0.76
87 Coordinate suppression of myeloma-specific genes and expression of fibroblast-specific genes in myeloma X fibroblast somatic cell hybrids. Somat Cell Mol Genet 1996 0.76
88 [Minimally invasive treatment of congenital foot deformities in infants: new findings and midterm-results]. Orthopade 2013 0.76
89 Clinical significance of apoptotic index in non-small cell lung cancer: correlation with p53, mdm2, pRb and p21WAF1/CIP1 protein expression. J Cancer Res Clin Oncol 2005 0.76
90 [Elastic stable intramedullary nailing as alternative therapy for the management of paediatric humeral shaft fractures]. Z Orthop Unfall 2009 0.76
91 [Coxitis fugax--the beginning of Perthes' disease?]. Z Orthop Ihre Grenzgeb 2006 0.75
92 [The effect of asbestos cement, UICC asbestos samples and quartz on the peritoneum of the mouse]. Pathol Microbiol (Basel) 1975 0.75
93 False-positive sonographic hip examinations in newborns with congenital varus deformity of the proximal femur. Arch Orthop Trauma Surg 1995 0.75
94 [Multi-dimensional evaluation of pain perception and its importance for the behavior of patients with chronic low back pain.]. Schmerz 1991 0.75
95 [Arthroscopic therapy of septic hip infections in childhood]. Oper Orthop Traumatol 2014 0.75
96 [Alpha-1-antitrypsin in the cord blood]. Gynakol Rundsch 1980 0.75
97 [Contribution to the study of medullary lines in reptiles: the granulocytic, lymphocytic and monocytic lines]. C R Acad Sci Hebd Seances Acad Sci D 1972 0.75
98 [Comparison of the diagnostic value of X-ray versus MRI in paediatric spine injuries]. Z Orthop Unfall 2011 0.75
99 [Participation refusal by probands in an epidemiologic long-term study--sociodemographic, clinical and psychometric findings]. Psychother Psychosom Med Psychol 1992 0.75
100 Application of differential cDNA screening techniques to the identification of unique gene expression in tumours and lymphocytes. Curr Opin Immunol 1998 0.75
101 Comprehensive comparison of various techniques for the analysis of elemental distributions in thin films. Microsc Microanal 2011 0.75
102 ICPD perspectives: institutional views. U.S., other countries increase efforts. Netw Res Triangle Park N C 1995 0.75
103 [Contribution to the study of medullary lines in reptiles. Erythrocyte and plasmocyte lines]. C R Acad Sci Hebd Seances Acad Sci D 1972 0.75
104 [An update on thrombosis prophylaxis in orthopaedic and accident surgery]. Orthopade 2004 0.75
105 [Psychometric assessment of defense mechanisms: correlation between questionnaire and expert rating. Initial study of validity]. Psychother Psychosom Med Psychol 1993 0.75
106 [Pseudarthrosis following surgically treated forearm fractures in children and adolescents]. Z Orthop Unfall 2013 0.75
107 [Results of ACL reconstruction with a periost-patella tendon-periost graft in growth age]. Z Orthop Unfall 2007 0.75
108 [Clubfoot associated with tibial and fibular hemimelia]. Z Orthop Unfall 2012 0.75
109 [Monitoring of clomiphene treatment]. Gynakol Rundsch 1980 0.75
110 [Determination of femoral head position with transinguinal ultrasound in DDH treatment]. Z Orthop Unfall 2009 0.75
111 [Acute traumatic and especially neglected traumatic hip dislocations are very rare in children]. Unfallchirurg 2012 0.75
112 [Feminizing adrenal cortex carcinoma in a 66-year-old man]. Schweiz Med Wochenschr 1977 0.75
113 Mimicry of lyme arthritis by synovial hemangioma. Rheumatol Int 2009 0.75