Published in Circ Res on June 10, 2004
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Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature (2003) 9.79
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nat Med (2007) 5.89
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Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes (2002) 3.04
Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance. J Clin Invest (2007) 2.81
In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue. J Clin Invest (2008) 2.78
Measurement of the high-molecular weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome. Diabetes Care (2006) 2.77
Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling. Nat Med (2002) 2.61
Gene expression in fibroblasts and fibrosis: involvement in cardiac hypertrophy. Circ Res (2002) 2.59
Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression. Hepatology (2003) 2.52
Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload. J Clin Invest (2009) 2.46
Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle. Cell Metab (2011) 2.42
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SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta. Nat Med (2008) 2.16
Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. J Biol Chem (2004) 2.15
G-CSF stimulates angiogenesis and promotes tumor growth: potential contribution of bone marrow-derived endothelial progenitor cells. Biochem Biophys Res Commun (2002) 2.13
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. J Exp Med (2010) 2.08
Mid-term results and costs of coronary artery bypass vs drug-eluting stents for unprotected left main coronary artery disease. Circ J (2010) 2.08
Hemizygous deficiency of Krüppel-like factor 2 augments experimental atherosclerosis. Circ Res (2008) 1.94
Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways. J Biol Chem (2006) 1.93
Association between hepatitis C virus seropositivity, carotid-artery plaque, and intima-media thickening. Lancet (2002) 1.92
Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine-endothelial cell interactions. Biochem Biophys Res Commun (2004) 1.92
The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages. Circ Res (2010) 1.92
A novel PPAR gamma gene therapy to control inflammation associated with inflammatory bowel disease in a murine model. Gastroenterology (2003) 1.91
Age and preoperative total bilirubin level can stratify prognosis after extracorporeal pulsatile left ventricular assist device implantation. Circ J (2010) 1.91
Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus. J Clin Invest (2004) 1.88
In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage. Hypertension (2002) 1.88
Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding. Cell Metab (2008) 1.86
Bone marrow-derived cells contribute to vascular inflammation but do not differentiate into smooth muscle cell lineages. Circulation (2010) 1.83
Association between serum uric acid, metabolic syndrome, and carotid atherosclerosis in Japanese individuals. Arterioscler Thromb Vasc Biol (2005) 1.82
Synthetic retinoid Am80 suppresses smooth muscle phenotypic modulation and in-stent neointima formation by inhibiting KLF5. Circ Res (2005) 1.82
Diverse contribution of bone marrow cells to neointimal hyperplasia after mechanical vascular injuries. Circ Res (2003) 1.80
Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jkappa-dependent pathway. J Biol Chem (2006) 1.78
Characterization of the mouse aortic carboxypeptidase-like protein promoter reveals activity in differentiated and dedifferentiated vascular smooth muscle cells. Circ Res (2002) 1.78
Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation. Cell Metab (2012) 1.77
PPARgamma ligand inhibits osteopontin gene expression through interference with binding of nuclear factors to A/T-rich sequence in THP-1 cells. Circ Res (2002) 1.75
DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation. Dev Cell (2006) 1.75
Electrocardiographic characteristics and SCN5A mutations in idiopathic ventricular fibrillation associated with early repolarization. Circ Arrhythm Electrophysiol (2011) 1.74
SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation. J Am Soc Nephrol (2009) 1.70
Ultrasound-microbubble-mediated intercellular adhesion molecule-1 small interfering ribonucleic acid transfection attenuates neointimal formation after arterial injury in mice. J Am Coll Cardiol (2010) 1.68
Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis. Proc Natl Acad Sci U S A (2012) 1.61
Changes in waist circumference and body mass index in relation to changes in serum uric acid in Japanese individuals. J Rheumatol (2009) 1.58
Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a beta-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c. Endocrinology (2004) 1.58
Novel risk scoring system with preoperative objective parameters gives a good prediction of 1-year mortality in patients with a left ventricular assist device. Circ J (2012) 1.56
The ATP-binding cassette transporter ABCG2 protects against pressure overload-induced cardiac hypertrophy and heart failure by promoting angiogenesis and antioxidant response. Arterioscler Thromb Vasc Biol (2011) 1.56
Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice. J Clin Invest (2011) 1.56
Relationship between the structure of SET/TAF-Ibeta/INHAT and its histone chaperone activity. Proc Natl Acad Sci U S A (2007) 1.55
Iron chelation suppresses ferritin upregulation and attenuates vascular dysfunction in the aorta of angiotensin II-infused rats. Arterioscler Thromb Vasc Biol (2005) 1.54
Fatty liver incidence and predictive variables. Hypertens Res (2010) 1.54
Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis. J Hepatol (2013) 1.52
Klf5 is involved in self-renewal of mouse embryonic stem cells. J Cell Sci (2008) 1.51
Preoperative levels of bilirubin or creatinine adjusted by age can predict their reversibility after implantation of left ventricular assist device. Circ J (2012) 1.51
Incidence and prognostic value of early repolarization pattern in the 12-lead electrocardiogram. Circulation (2011) 1.49
Role of endogenous adrenomedullin in the regulation of vascular tone and ischemic renal injury: studies on transgenic/knockout mice of adrenomedullin gene. Circ Res (2002) 1.49
Differences in body temperature variability between subjects with and without diabetes and predictive value for cardiovascular events. Circ J (2013) 1.47