Published in JAMA on June 16, 2004
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet (2007) 5.02
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet (2009) 3.80
Genome-wide association study of PR interval. Nat Genet (2010) 3.73
Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop. Circulation (2009) 3.50
Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes. BMC Med Genet (2007) 2.93
Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association. Circulation (2017) 2.76
Polymorphism modulates symptomatic response to antiarrhythmic drug therapy in patients with lone atrial fibrillation. Heart Rhythm (2007) 2.62
Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation. Circulation (2008) 2.56
Familial aggregation in lone atrial fibrillation. Hum Genet (2005) 2.55
P wave duration and risk of longitudinal atrial fibrillation in persons ≥ 60 years old (from the Framingham Heart Study). Am J Cardiol (2011) 2.39
Atrial fibrillation: current knowledge and future directions in epidemiology and genomics. Circulation (2011) 2.36
A common polymorphism in SCN5A is associated with lone atrial fibrillation. Clin Pharmacol Ther (2007) 2.17
Atrial natriuretic peptide frameshift mutation in familial atrial fibrillation. N Engl J Med (2008) 2.14
2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. J Interv Card Electrophysiol (2012) 2.08
Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. Eur Heart J (2009) 2.06
Genetics of acquired long QT syndrome. J Clin Invest (2005) 1.96
Pharmacogenomics: challenges and opportunities. Ann Intern Med (2006) 1.96
Independent susceptibility markers for atrial fibrillation on chromosome 4q25. Circulation (2010) 1.90
European ancestry as a risk factor for atrial fibrillation in African Americans. Circulation (2010) 1.90
Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation. Heart Rhythm (2009) 1.87
Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. J Am Coll Cardiol (2014) 1.86
Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation. J Am Coll Cardiol (2012) 1.84
Status of the epidemiology of atrial fibrillation. Med Clin North Am (2008) 1.80
Prolonged signal-averaged P-wave duration as an intermediate phenotype for familial atrial fibrillation. J Am Coll Cardiol (2008) 1.77
Association between familial atrial fibrillation and risk of new-onset atrial fibrillation. JAMA (2010) 1.75
R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation. Heart Rhythm (2010) 1.71
X-linked nonsyndromic sinus node dysfunction and atrial fibrillation caused by emerin mutation. J Cardiovasc Electrophysiol (2008) 1.68
Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery. Circ Cardiovasc Genet (2009) 1.59
Lack of replication in polymorphisms reported to be associated with atrial fibrillation. Heart Rhythm (2010) 1.58
Current perceptions of the epidemiology of atrial fibrillation. Cardiol Clin (2009) 1.38
Familial aggregation of atrial fibrillation: a study in Danish twins. Circ Arrhythm Electrophysiol (2009) 1.32
Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation. J Mol Cell Cardiol (2009) 1.31
Update on anti-coagulation in atrial fibrillation. QJM (2011) 1.28
Genome-wide association studies of atrial fibrillation: past, present, and future. Cardiovasc Res (2011) 1.27
Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation. Heart Rhythm (2008) 1.27
Genetics of atrial fibrillation: rare mutations, common polymorphisms, and clinical relevance. Heart Rhythm (2007) 1.23
Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels. J Physiol (2008) 1.22
Potassium channel gene mutations rarely cause atrial fibrillation. BMC Med Genet (2006) 1.21
Lone atrial fibrillation: does it exist? J Am Coll Cardiol (2014) 1.21
Genetics of atrial fibrillation. Heart Fail Clin (2010) 1.15
A first-degree family history in lone atrial fibrillation patients. Heart Rhythm (2008) 1.14
Genetic mechanisms of atrial fibrillation: impact on response to treatment. Nat Rev Cardiol (2013) 1.11
Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke. Stroke (2014) 1.08
Atrial fibrillation in congestive heart failure. Heart Fail Clin (2010) 1.07
Atrial fibrillation: basic mechanisms, remodeling and triggers. J Interv Card Electrophysiol (2005) 1.05
Cardiovascular genomics, personalized medicine, and the National Heart, Lung, and Blood Institute: part I: the beginning of an era. Circ Cardiovasc Genet (2008) 1.05
Atrial fibrillation in the elderly: the potential contribution of reactive oxygen species. J Geriatr Cardiol (2012) 1.02
Genetics of atrial fibrillation: implications for future research directions and personalized medicine. Circ Arrhythm Electrophysiol (2010) 1.01
American Heart Association atrial fibrillation research summit: a conference report from the American Heart Association. Circulation (2011) 0.97
Novel risk factors for atrial fibrillation: useful for risk prediction and clinical decision making? Circulation (2012) 0.97
Genetics of atrial fibrillation. Cardiol Clin (2009) 0.96
Genetics of atrial fibrillation: from families to genomes. J Hum Genet (2015) 0.96
Emerging directions in the genetics of atrial fibrillation. Circ Res (2014) 0.96
Monogenic atrial fibrillation as pathophysiological paradigms. Cardiovasc Res (2010) 0.94
Contemporary management of atrial fibrillation: update on anticoagulation and invasive management strategies. Mayo Clin Proc (2009) 0.93
Atrial fibrillation: the role of common and rare genetic variants. Eur J Hum Genet (2013) 0.92
Interleukin-6 promoter polymorphisms and susceptibility to atrial fibrillation in elderly Han Chinese patients with essential hypertension. J Interferon Cytokine Res (2012) 0.92
Atrial fibrillation and heart failure parallels: lessons for atrial fibrillation prevention. Crit Pathw Cardiol (2011) 0.92
Differential impact of race and risk factors on incidence of atrial fibrillation. Am Heart J (2011) 0.91
Comparison of Atrial Fibrillation in the Young versus That in the Elderly: A Review. Cardiol Res Pract (2013) 0.90
Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis. Nat Rev Cardiol (2016) 0.89
Genetics of atrial fibrillation. Med Clin North Am (2008) 0.88
Gene-guided therapy for catheter-ablation of atrial fibrillation: are we there yet? J Interv Card Electrophysiol (2015) 0.87
The "missing" link in atrial fibrillation heritability. J Electrocardiol (2011) 0.87
Genetic polymorphisms in ZFHX3 are associated with atrial fibrillation in a Chinese Han population. PLoS One (2014) 0.86
Pro-arrhythmogenic effects of the S140G KCNQ1 mutation in human atrial fibrillation - insights from modelling. J Physiol (2012) 0.86
Korean Atrial Fibrillation (AF) Network: Genetic Variants for AF Do Not Predict Ablation Success. J Am Heart Assoc (2015) 0.85
Common variation in atrial fibrillation: navigating the path from genetic association to mechanism. Cardiovasc Res (2016) 0.85
HapMap and mapping genes for cardiovascular disease. Circ Cardiovasc Genet (2008) 0.85
High familial risk of atrial fibrillation/atrial flutter in multiplex families: a nationwide family study in Sweden. J Am Heart Assoc (2012) 0.85
Atrial arrhythmogenesis in wild-type and Scn5a+/delta murine hearts modelling LQT3 syndrome. Pflugers Arch (2009) 0.85
Lone atrial fibrillation: influence of familial disease on gender predilection. J Cardiovasc Electrophysiol (2008) 0.84
Evaluation of non-synonymous NPPA single nucleotide polymorphisms in atrial fibrillation. Europace (2010) 0.84
Novel GATA5 loss-of-function mutations underlie familial atrial fibrillation. Clinics (Sao Paulo) (2012) 0.84
A contemporary review on the genetic basis of atrial fibrillation. Methodist Debakey Cardiovasc J (2014) 0.84
New advances in the genetic basis of atrial fibrillation. J Cardiovasc Electrophysiol (2012) 0.84
A novel trafficking-defective HCN4 mutation is associated with early-onset atrial fibrillation. Heart Rhythm (2014) 0.82
Predictors for atrial fibrillation detection after cryptogenic stroke: Results from CRYSTAL AF. Neurology (2015) 0.82
Genetic polymorphisms for estimating risk of atrial fibrillation: a literature-based meta-analysis. J Intern Med (2012) 0.81
Genomics: risk and outcomes in cardiac surgery. Anesthesiol Clin (2008) 0.81
A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern. Heart Rhythm (2012) 0.81
Outcomes Associated With Familial Versus Nonfamilial Atrial Fibrillation: A Matched Nationwide Cohort Study. J Am Heart Assoc (2016) 0.81
Genomics of Atrial Fibrillation. Curr Cardiol Rep (2016) 0.80
Selective targeting of gain-of-function KCNQ1 mutations predisposing to atrial fibrillation. Circ Arrhythm Electrophysiol (2013) 0.80
Trends in the association of parental history of obesity over 60 years. Obesity (Silver Spring) (2014) 0.80
Lone AF - etiologic factors and genetic insights into pathophysiolgy. J Atr Fibrillation (2010) 0.80
Genetic variants related to height and risk of atrial fibrillation: the cardiovascular health study. Am J Epidemiol (2014) 0.80
[Genetics of atrial fibrillation: rare mutations, common variants and clinical relevance?]. Herzschrittmacherther Elektrophysiol (2006) 0.79
Atrial natriuretic Peptide single nucleotide polymorphisms in patients with nonfamilial structural atrial fibrillation. Clin Med Insights Cardiol (2013) 0.79
Molecular genetics of atrial fibrillation. Genome Med (2009) 0.79
Mutational spectrum of the NKX2-5 gene in patients with lone atrial fibrillation. Int J Med Sci (2014) 0.79
Whole blood gene expression and atrial fibrillation: the Framingham Heart Study. PLoS One (2014) 0.79
Paired-like homeodomain 2: a novel therapeutic target for atrial fibrillation? Front Genet (2014) 0.79
Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med (2008) 57.29
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 56.72
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 41.47
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79
Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation (2010) 30.07
Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 26.95
General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation (2008) 26.42
Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation (2014) 22.74
2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2013) 17.18
Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol (2002) 16.25
Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med (2006) 15.60
Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers. Stat Med (2010) 14.49
Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation (2011) 14.00
Vitamin D deficiency and risk of cardiovascular disease. Circulation (2008) 13.39
Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association's strategic Impact Goal through 2020 and beyond. Circulation (2010) 13.28
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation (2007) 12.79
Obesity and the risk of heart failure. N Engl J Med (2002) 12.58
Metabolite profiles and the risk of developing diabetes. Nat Med (2011) 12.22
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation. Stat Med (2004) 11.46
Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010. Lancet (2012) 11.32
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med (2002) 11.20
A prospective natural-history study of coronary atherosclerosis. N Engl J Med (2011) 10.66
The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA (2013) 10.43
Long-term trends in the incidence of and survival with heart failure. N Engl J Med (2002) 10.37
2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation (2013) 10.24
Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation (2015) 10.14
The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination. Am J Epidemiol (2007) 9.90
Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med (2008) 9.68
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation (2010) 9.09
Stenting and medical therapy for atherosclerotic renal-artery stenosis. N Engl J Med (2013) 8.91
2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2013) 8.90
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation (2004) 8.80
Incidence of diabetes in youth in the United States. JAMA (2007) 8.70
Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study. Arch Intern Med (2007) 8.59
Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation (2005) 8.54
Lifetime risk for developing congestive heart failure: the Framingham Heart Study. Circulation (2002) 8.49
Changes in arterial stiffness and wave reflection with advancing age in healthy men and women: the Framingham Heart Study. Hypertension (2004) 8.27
Application of new cholesterol guidelines to a population-based sample. N Engl J Med (2014) 8.22
2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2010) 7.54
Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol (2003) 7.47
Predictors of new-onset kidney disease in a community-based population. JAMA (2004) 7.45
Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. Circulation (2003) 7.40
Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study. Lancet (2009) 7.27
The burden of diabetes mellitus among US youth: prevalence estimates from the SEARCH for Diabetes in Youth Study. Pediatrics (2006) 7.19
Plasma natriuretic peptide levels and the risk of cardiovascular events and death. N Engl J Med (2004) 7.12