Published in Kidney Int on July 01, 2004
Mechanisms of Cisplatin nephrotoxicity. Toxins (Basel) (2010) 2.99
Xenobiotic, bile acid, and cholesterol transporters: function and regulation. Pharmacol Rev (2010) 2.97
Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity. Clin Pharmacol Ther (2009) 1.94
Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions. Am J Pathol (2010) 1.76
Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2. Am J Pathol (2005) 1.73
cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects. Proc Natl Acad Sci U S A (2008) 1.62
The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity. Am J Physiol Renal Physiol (2009) 1.56
Klotho has dual protective effects on cisplatin-induced acute kidney injury. Kidney Int (2013) 1.06
Influence of Oct1/Oct2-deficiency on cisplatin-induced changes in urinary N-acetyl-beta-D-glucosaminidase. Clin Cancer Res (2010) 1.01
The association of transporter genes polymorphisms and lung cancer chemotherapy response. PLoS One (2014) 0.87
Resveratrol attenuates cisplatin renal cortical cytotoxicity by modifying oxidative stress. Toxicol In Vitro (2013) 0.83
Gender difference in Cisplatin-induced nephrotoxicity in a rat model. Nephrourol Mon (2015) 0.82
Membrane transporters as mediators of Cisplatin effects and side effects. Scientifica (Cairo) (2012) 0.81
Chloroacetaldehyde- and acrolein-induced death of human proximal tubule cells. Pediatr Nephrol (2005) 0.81
Basolateral BMP signaling in polarized epithelial cells. PLoS One (2013) 0.79
Contributions of the Epidermal Growth Factor Receptor to Acquisition of Platinum Resistance in Ovarian Cancer Cells. PLoS One (2015) 0.77
Acidic priming enhances metastatic potential of cancer cells. Pflugers Arch (2014) 0.77
Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics. Drug Metab Dispos (2016) 0.76
A new approach to reduce toxicities and to improve bioavailabilities of platinum-containing anti-cancer nanodrugs. Sci Rep (2015) 0.76
Lower blood pressure and risk of cisplatin nephrotoxicity: a retrospective cohort study. BMC Cancer (2017) 0.75
Immunohistochemical localization of OCT2 in the cochlea of various species. Laryngoscope (2015) 0.75
Conformational landscape of platinum(II)-tetraamine complexes: DFT and NBO studies. J Comput Aided Mol Des (2010) 0.75
Xenobiotic transporters and kidney injury. Adv Drug Deliv Rev (2017) 0.75
Protective effect of ginsenosides Rk3 and Rh4 on cisplatin-induced acute kidney injury in vitro and in vivo. J Ginseng Res (2016) 0.75
Premedication with intravenous magnesium has a protective effect against cisplatin-induced nephrotoxicity. Support Care Cancer (2016) 0.75
Plasma sodium stiffens vascular endothelium and reduces nitric oxide release. Proc Natl Acad Sci U S A (2007) 1.98
C-reactive protein makes human endothelium stiff and tight. Hypertension (2010) 1.91
Epithelial sodium channel stiffens the vascular endothelium in vitro and in Liddle mice. Hypertension (2013) 1.70
Human endothelium: target for aldosterone. Hypertension (2004) 1.61
High phosphate directly affects endothelial function by downregulating annexin II. Kidney Int (2012) 1.57
Loss of epidermal growth factor receptor in vascular smooth muscle cells and cardiomyocytes causes arterial hypotension and cardiac hypertrophy. Hypertension (2012) 1.54
Nuclear shuttling precedes dimerization in mineralocorticoid receptor signaling. Chem Biol (2012) 1.50
The soluble VEGF receptor sFlt1 contributes to endothelial dysfunction in CKD. J Am Soc Nephrol (2009) 1.50
Aldosterone stimulates surface expression of NHE3 in renal proximal brush borders. Pflugers Arch (2003) 1.47
Translocation of aquaporin-containing vesicles to the plasma membrane is facilitated by actomyosin relaxation. Biophys J (2007) 1.47
Ca2+ but not H2O2 modulates GRE-element activation by the human mineralocorticoid receptor in HEK cells. Mol Cell Endocrinol (2006) 1.46
Soluble plasma-derived von Willebrand factor assembles to a haemostatically active filamentous network. Thromb Haemost (2007) 1.32
Microtubule-dependent matrix metalloproteinase-2/matrix metalloproteinase-9 exocytosis: prerequisite in human melanoma cell invasion. Cancer Res (2004) 1.23
Angiotensin converting enzyme inhibition and angiotensin II AT1-receptor blockade reduce the levels of asymmetrical N(G), N(G)-dimethylarginine in human essential hypertension. Am J Hypertens (2002) 1.19
Real-time monitoring of cell elasticity reveals oscillating myosin activity. Biophys J (2010) 1.19
Aldosterone and amiloride alter ENaC abundance in vascular endothelium. Pflugers Arch (2007) 1.13
Glioblastoma cells release factors that disrupt blood-brain barrier features. Acta Neuropathol (2004) 1.12
Megalin is essential for renal proximal tubule reabsorption of (111)In-DTPA-octreotide. J Nucl Med (2005) 1.07
Differential action of steroid hormones on human endothelium. J Cell Sci (2006) 1.06
Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs. Neoplasia (2006) 1.02
Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1) in vitro and in vivo by increasing the activity of the p-glycoprotein via activation of p38. Int J Cancer (2008) 1.02
Aldosterone-induced EGFR expression: interaction between the human mineralocorticoid receptor and the human EGFR promoter. Am J Physiol Endocrinol Metab (2007) 1.01
Membrane potential depolarization decreases the stiffness of vascular endothelial cells. J Cell Sci (2011) 0.99
Nanomechanics of the endothelial glycocalyx in experimental sepsis. PLoS One (2013) 0.98
The epithelial sodium channel (ENaC): Mediator of the aldosterone response in the vascular endothelium? Steroids (2009) 0.97
Albumin induces NF-kappaB expression in human proximal tubule-derived cells (IHKE-1). Cell Physiol Biochem (2002) 0.97
Atrial natriuretic peptide and nitric oxide signaling antagonizes vasopressin-mediated water permeability in inner medullary collecting duct cells. Am J Physiol Renal Physiol (2009) 0.96
Human mineralocorticoid receptor expression renders cells responsive for nongenotropic aldosterone actions. Mol Endocrinol (2005) 0.96
Aldosterone stimulates epidermal growth factor receptor expression. J Biol Chem (2003) 0.96
Role of cellular mechanics in the function and life span of vascular endothelium. Pflugers Arch (2011) 0.96
A pathway separate from the central channel through the nuclear pore complex for inorganic ions and small macromolecules. J Biol Chem (2007) 0.96
Cyclical mechanical stretch modulates expression of collagen I and collagen III by PKC and tyrosine kinase in cardiac fibroblasts. Am J Physiol Regul Integr Comp Physiol (2007) 0.95
Dynamics of single potassium channel proteins in the plasma membrane of migrating cells. Am J Physiol Cell Physiol (2008) 0.95
The role of ENaC in vascular endothelium. Pflugers Arch (2013) 0.94
Pathogenesis of hypertension: interactions among sodium, potassium, and aldosterone. Am J Kidney Dis (2010) 0.94
Acidic environment leads to ROS-induced MAPK signaling in cancer cells. PLoS One (2011) 0.94
Long-term application of the aldosterone antagonist spironolactone prevents stiff endothelial cell syndrome. FASEB J (2013) 0.94
Implementation of an in vitro model system for investigation of reperfusion damage after renal ischemia. Cell Physiol Biochem (2009) 0.94
Exceptional mechanical and structural stability of HSV-1 unveiled with fluid atomic force microscopy. J Cell Sci (2008) 0.94
Firewall function of the endothelial glycocalyx in the regulation of sodium homeostasis. Pflugers Arch (2011) 0.93
Metabolism and cytotoxic effects of T-2 toxin and its metabolites on human cells in primary culture. Toxicology (2009) 0.92
Evidence for epidermal growth factor receptor as negative-feedback control in aldosterone-induced Na+ reabsorption. Am J Physiol Renal Physiol (2004) 0.91
Ménage à trois: aldosterone, sodium and nitric oxide in vascular endothelium. Biochim Biophys Acta (2010) 0.91
Reduced number of CFTR molecules in erythrocyte plasma membrane of cystic fibrosis patients. Mol Membr Biol (2006) 0.91
Nitric oxide release follows endothelial nanomechanics and not vice versa. Pflugers Arch (2010) 0.90
Paracellular permeability of bronchial epithelium is controlled by CFTR. Cell Physiol Biochem (2011) 0.90
Inhibition of cardiac pacemaker channel hHCN2 depends on intercalation of lipopolysaccharide into channel-containing membrane microdomains. J Physiol (2013) 0.90
Simultaneous mechanical stiffness and electrical potential measurements of living vascular endothelial cells using combined atomic force and epifluorescence microscopy. Nanotechnology (2009) 0.89
Structure-toxicity relationships for different types of dinuclear platinum complexes. J Inorg Biochem (2006) 0.89
The genome of HSV-1 translocates through the nuclear pore as a condensed rod-like structure. J Cell Sci (2005) 0.89
Human epidermal growth factor receptor-1 expression renders Chinese hamster ovary cells sensitive to alternative aldosterone signaling. J Biol Chem (2002) 0.88
Steroids dilate nuclear pores imaged with atomic force microscopy. J Cell Physiol (2005) 0.88
Vacuolar structures can be identified by AFM elasticity mapping. Ultramicroscopy (2007) 0.88
EF domains are sufficient for nongenomic mineralocorticoid receptor actions. J Biol Chem (2008) 0.88
Mineralocorticoid receptor inhibits CREB signaling by calcineurin activation. FASEB J (2010) 0.88
Nanomechanics and sodium permeability of endothelial surface layer modulated by hawthorn extract WS 1442. PLoS One (2012) 0.87
Nongenotropic aldosterone effects and the EGFR: interaction and biological relevance. Steroids (2007) 0.87
Glucocorticoids remodel nuclear envelope structure and permeability. J Cell Sci (2005) 0.86
Nebivolol decreases endothelial cell stiffness via the estrogen receptor beta: a nano-imaging study. J Hypertens (2009) 0.86
Hypoxia-induced extracellular acidosis increases p-glycoprotein activity and chemoresistance in tumors in vivo via p38 signaling pathway. Adv Exp Med Biol (2011) 0.86
Nanomechanics of vascular endothelium. Cell Tissue Res (2014) 0.86
The dermatan sulfate proteoglycan decorin modulates α2β1 integrin and the vimentin intermediate filament system during collagen synthesis. PLoS One (2012) 0.85
Role of the tumor microenvironment in the activity and expression of the p-glycoprotein in human colon carcinoma cells. Oncol Rep (2007) 0.85
Cisplatin-induced apoptosis is enhanced by hypoxia and by inhibition of mitochondria in renal collecting duct cells. Toxicol Sci (2005) 0.85
Direct aldosterone action on mouse cardiomyocytes detected with atomic force microscopy. Cell Physiol Biochem (2006) 0.85
Ochratoxin A at nanomolar concentrations: a signal modulator in renal cells. Mol Nutr Food Res (2005) 0.85
Nuclear envelope barrier leak induced by dexamethasone. J Cell Physiol (2006) 0.85
Protein uptake disturbs collagen homeostasis in proximal tubule-derived cells. Kidney Int Suppl (2003) 0.84
Imaging CFTR: a tail to tail dimer with a central pore. Cell Physiol Biochem (2004) 0.84
Prostaglandin E2 inhibits its own renal transport by downregulation of organic anion transporters rOAT1 and rOAT3. J Am Soc Nephrol (2005) 0.84
Nuclear delivery mechanism of herpes simplex virus type 1 genome. J Mol Recognit (2011) 0.84
Transient activation and delayed inhibition of Na+,K+,Cl- cotransport in ATP-treated C11-MDCK cells involve distinct P2Y receptor subtypes and signaling mechanisms. J Biol Chem (2006) 0.84
Aldosterone stimulates activity and surface expression of NHE3 in human primary proximal tubule epithelial cells (RPTEC). Cell Physiol Biochem (2006) 0.84
Activity of drug efflux transporters in tumor cells under hypoxic conditions. Adv Exp Med Biol (2008) 0.84
Shape and volume of living aldosterone-sensitive cells imaged with the atomic force microscope. Methods Mol Biol (2004) 0.84
Structural organization of the nuclear pore permeability barrier. J Control Release (2012) 0.83
Long-term effects of ochratoxin A on fibrosis and cell death in human proximal tubule or fibroblast cells in primary culture. Toxicology (2006) 0.83
Short-term regulation of basolateral organic anion uptake in proximal tubular opossum kidney cells: prostaglandin E2 acts via receptor-mediated activation of protein kinase A. J Am Soc Nephrol (2003) 0.83
Nanotopography follows force in TGF-beta1 stimulated epithelium. Nanotechnology (2010) 0.83
IADS, a decomposition product of DIDS activates a cation conductance in Xenopus oocytes and human erythrocytes: new compound for the diagnosis of cystic fibrosis. Cell Physiol Biochem (2006) 0.83
Colocalization of mineralocorticoid and EGF receptor at the plasma membrane. Biochim Biophys Acta (2010) 0.82
Cortical actin nanodynamics determines nitric oxide release in vascular endothelium. PLoS One (2012) 0.82
Role of epidermal growth factor receptor in vascular structure and function. Curr Opin Nephrol Hypertens (2014) 0.82
The electrical resistance breakdown assay determines the role of proteinases in tumor cell invasion. Am J Physiol Renal Physiol (2002) 0.82
Effects of the mycotoxin deoxynivalenol on human primary hepatocytes. Mol Nutr Food Res (2008) 0.82
Dose-dependent endothelial cell growth and stiffening by aldosterone: endothelial protection by eplerenone. J Hypertens (2007) 0.81
Non-classical actions of the mineralocorticoid receptor: misuse of EGF receptors? Mol Cell Endocrinol (2007) 0.81
Delay of acute intracellular pH recovery after acidosis decreases endothelial cell activation. J Cell Physiol (2007) 0.81
Disturbed Ca2+-signaling by chloroacetaldehyde: a possible cause for chronic ifosfamide nephrotoxicity. Kidney Int (2005) 0.81
Determination of CFTR densities in erythrocyte plasma membranes using recognition imaging. Nanotechnology (2008) 0.81
The nephrotoxin ochratoxin A induces key parameters of chronic interstitial nephropathy in renal proximal tubular cells. Cell Physiol Biochem (2005) 0.81
Impact of hypoxic and acidic extracellular conditions on cytotoxicity of chemotherapeutic drugs. Adv Exp Med Biol (2007) 0.81
Activation of cell migration with fibroblast growth factor-2 requires calcium-sensitive potassium channels. Pflugers Arch (2008) 0.81
Chloroacetaldehyde- and acrolein-induced death of human proximal tubule cells. Pediatr Nephrol (2005) 0.81