Published in Int J Oncol on July 01, 2004
Characterization of enantiomeric bile acid-induced apoptosis in colon cancer cell lines. J Biol Chem (2008) 1.01
Intestinal bile acid physiology and pathophysiology. World J Gastroenterol (2008) 0.95
Chemical and biological analysis of active free and conjugated bile acids in animal bile using HPLC-ELSD and MTT methods. Exp Ther Med (2010) 0.78
NO Photoreleaser-Deoxyadenosine and -Bile Acid Derivative Bioconjugates as Novel Potential Photochemotherapeutics. ACS Med Chem Lett (2016) 0.75
Chenodeoxycholic Acid Derivative HS-1200 Inhibits Hepatocarcinogenesis and Improves Liver Function in Diethylnitrosamine-Exposed Rats by Downregulating MTH1. Biomed Res Int (2017) 0.75
Prospective serum metabolomic profile of prostate cancer by size and extent of primary tumor. Oncotarget (2017) 0.75
K-RAS transformation in prostate epithelial cell overcomes H2O2-induced apoptosis via upregulation of gamma-glutamyltransferase-2. Toxicol In Vitro (2012) 2.03
Systemic adaptation to oxidative challenge induced by regular exercise. Free Radic Biol Med (2007) 1.74
Age-associated increase in oxidative stress and nuclear factor kappaB activation are attenuated in rat liver by regular exercise. FASEB J (2004) 1.65
Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus. J Biol Chem (2008) 1.55
Gene signatures for the prediction of response to Bacillus Calmette-Guerin immunotherapy in primary pT1 bladder cancers. Clin Cancer Res (2010) 1.52
Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippocampal cells. Eur J Pharmacol (2009) 1.48
Gefitinib induces apoptosis and decreases telomerase activity in MDA-MB-231 human breast cancer cells. Arch Pharm Res (2009) 1.47
Modulation of redox-sensitive transcription factors by calorie restriction during aging. Mech Ageing Dev (2002) 1.41
4-(6-Hydroxy-2-naphthyl)-1,3-bezendiol: a potent, new tyrosinase inhibitor. Biol Pharm Bull (2007) 1.40
Exercise and hormesis: oxidative stress-related adaptation for successful aging. Biogerontology (2005) 1.40
A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain-derived neurotrophic factor. Neurosci Lett (2010) 1.36
Modulation of PPAR in aging, inflammation, and calorie restriction. J Gerontol A Biol Sci Med Sci (2004) 1.31
Caspase-dependent and caspase-independent apoptosis induced by evodiamine in human leukemic U937 cells. Mol Cancer Ther (2006) 1.26
Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia. Int Immunopharmacol (2007) 1.19
Induction of apoptosis by withaferin A in human leukemia U937 cells through down-regulation of Akt phosphorylation. Apoptosis (2008) 1.19
The activation of NF-kappaB through Akt-induced FOXO1 phosphorylation during aging and its modulation by calorie restriction. Biogerontology (2007) 1.17
Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes. Liver Int (2009) 1.17
Sulforaphane suppresses TNF-alpha-mediated activation of NF-kappaB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3. Cancer Lett (2008) 1.17
Guggulsterone sensitizes hepatoma cells to TRAIL-induced apoptosis through the induction of CHOP-dependent DR5: involvement of ROS-dependent ER-stress. Biochem Pharmacol (2011) 1.14
Caffeic acid phenethyl ester protects mice from lethal endotoxin shock and inhibits lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 macrophages via the p38/ERK and NF-kappaB pathways. Int J Biochem Cell Biol (2008) 1.14
A four-gene signature predicts disease progression in muscle invasive bladder cancer. Mol Med (2011) 1.14
Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death. Free Radic Biol Med (2010) 1.13
Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling. Toxicol Appl Pharmacol (2009) 1.13
Mitochondrial iron accumulation with age and functional consequences. Aging Cell (2008) 1.12
Regulation of replicative senescence by insulin-like growth factor-binding protein 3 in human umbilical vein endothelial cells. Aging Cell (2007) 1.11
In vitro and in vivo anticancer effects of Lithospermum erythrorhizon extract on B16F10 murine melanoma. J Ethnopharmacol (2012) 1.11
Adaptive mechanisms to oxidative stress during aging. Mech Ageing Dev (2006) 1.10
Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells. Food Chem Toxicol (2011) 1.09
Activation of CXCR2 by extracellular matrix degradation product acetylated Pro-Gly-Pro has therapeutic effects against sepsis. Am J Respir Crit Care Med (2011) 1.08
Cilostazol is anti-inflammatory in BV2 microglial cells by inactivating nuclear factor-kappaB and inhibiting mitogen-activated protein kinases. Br J Pharmacol (2010) 1.08
Antimutagenic effects of doenjang (Korean fermented soypaste) and its active compounds. Mutat Res (2003) 1.07
Upregulation of aortic adhesion molecules during aging. J Gerontol A Biol Sci Med Sci (2006) 1.07
Peroxynitrite scavenging activity of herb extracts. Phytother Res (2002) 1.07
Dichloromethane fraction of Cimicifuga heracleifolia decreases the level of melanin synthesis by activating the ERK or AKT signaling pathway in B16F10 cells. Exp Dermatol (2008) 1.07
Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-κB in LPS-stimulated RAW264.7 cells and mouse liver. J Ginseng Res (2013) 1.06
Tetrandrine-induced cell cycle arrest and apoptosis in A549 human lung carcinoma cells. Int J Oncol (2002) 1.06
Alteration of soluble adhesion molecules during aging and their modulation by calorie restriction. FASEB J (2003) 1.05
Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. Free Radic Biol Med (2007) 1.04
Induction of apoptosis by cordycepin via reactive oxygen species generation in human leukemia cells. Toxicol In Vitro (2011) 1.03
Involvement of p21WAF1/CIP1, pRB, Bax and NF-kappaB in induction of growth arrest and apoptosis by resveratrol in human lung carcinoma A549 cells. Int J Oncol (2003) 1.03
Platycodin D induces mitotic arrest in vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells. Int J Cancer (2008) 1.02
Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells. Biomed Pharmacother (2008) 1.01
Inhibition of HIF-1 alpha and VEGF expression by the chemopreventive bioflavonoid apigenin is accompanied by Akt inhibition in human prostate carcinoma PC3-M cells. Mol Carcinog (2008) 1.01
Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion. PLoS One (2012) 1.01
Nidogen is a prosurvival and promigratory factor for adult Schwann cells. J Neurochem (2007) 1.00
Inhibitory phlorotannins from the edible brown alga Ecklonia stolonifera on total reactive oxygen species (ROS) generation. Arch Pharm Res (2004) 1.00
Molecular mechanism of PPAR in the regulation of age-related inflammation. Ageing Res Rev (2008) 0.99
Induction of apoptosis and autophagy by sodium selenite in A549 human lung carcinoma cells through generation of reactive oxygen species. Toxicol Lett (2012) 0.99
Genistein sensitizes TRAIL-resistant human gastric adenocarcinoma AGS cells through activation of caspase-3. Cancer Lett (2007) 0.99
Genome-scale analysis of resveratrol-induced gene expression profile in human ovarian cancer cells using a cDNA microarray. Int J Oncol (2003) 0.98
Differential inhibitory effects of baicalein and baicalin on LPS-induced cyclooxygenase-2 expression through inhibition of C/EBPbeta DNA-binding activity. Immunobiology (2006) 0.98
Beta-sitosterol induces anti-proliferation and apoptosis in human leukemic U937 cells through activation of caspase-3 and induction of Bax/Bcl-2 ratio. Biol Pharm Bull (2007) 0.98
Curcumin attenuates inflammatory response in IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model. Int Immunopharmacol (2010) 0.98
Resveratrol induces pro-apoptotic endoplasmic reticulum stress in human colon cancer cells. Oncol Rep (2007) 0.98
Hormetic effects of regular exercise in aging: correlation with oxidative stress. Appl Physiol Nutr Metab (2007) 0.98
Korean red ginseng extract induces apoptosis and decreases telomerase activity in human leukemia cells. J Ethnopharmacol (2008) 0.97
Aspirin induces apoptosis in vitro and inhibits tumor growth of human hepatocellular carcinoma cells in a nude mouse xenograft model. Int J Oncol (2011) 0.97
Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK. Toxicol Appl Pharmacol (2007) 0.97
Hesperetin: a potent antioxidant against peroxynitrite. Free Radic Res (2004) 0.97
Modulation of gene expression of SMP-30 by LPS and calorie restriction during aging process. Exp Gerontol (2004) 0.97
Interleukin-6 is required for the early induction of glial fibrillary acidic protein in Schwann cells during Wallerian degeneration. J Neurochem (2009) 0.97
Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis. Int J Mol Med (2007) 0.97
Anti-wrinkle and anti-inflammatory effects of active garlic components and the inhibition of MMPs via NF-κB signaling. PLoS One (2013) 0.97
Antibacterial polyketides from the jellyfish-derived fungus Paecilomyces variotii. J Nat Prod (2011) 0.96
Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: suppression of p38, JNK and NF-kappaB p65 as potential targets. Biol Pharm Bull (2006) 0.96
Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells. Cancer Lett (2008) 0.96
Anti-inflammatory action of dietary fish oil and calorie restriction. Life Sci (2006) 0.96
Resveratrol inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression in beta-amyloid-treated C6 glioma cells. Int J Mol Med (2006) 0.96
Anti-inflammatory effects of beta-lapachone in lipopolysaccharide-stimulated BV2 microglia. Int Immunopharmacol (2007) 0.96
In vitro antioxidant activity of some selected Prunus species in Korea. Arch Pharm Res (2002) 0.96
Induction of apoptosis and inhibition of telomerase activity by trichostatin A, a histone deacetylase inhibitor, in human leukemic U937 cells. Exp Mol Pathol (2006) 0.95
Induction of G2/M arrest and apoptosis by water extract of Strychni Semen in human gastric carcinoma AGS cells. Phytother Res (2008) 0.95
Suppression of apoptosis by calorie restriction in aged kidney. Exp Gerontol (2004) 0.95
Anti-inflammatory effects of cordycepin via suppression of inflammatory mediators in BV2 microglial cells. Int Immunopharmacol (2010) 0.95
Inhibition of migration and invasion of LNCaP human prostate carcinoma cells by cordycepin through inactivation of Akt. Int J Oncol (2012) 0.95
Amelioration of age-related inflammation and oxidative stress by PPARgamma activator: suppression of NF-kappaB by 2,4-thiazolidinedione. Exp Gerontol (2006) 0.95
Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells. Oncol Rep (2012) 0.95
Induction of apoptosis by aqueous extract of Cordyceps militaris through activation of caspases and inactivation of Akt in human breast cancer MDA-MB-231 Cells. J Microbiol Biotechnol (2008) 0.94
Apoptosis induction of human bladder cancer cells by sanguinarine through reactive oxygen species-mediated up-regulation of early growth response gene-1. PLoS One (2013) 0.94
Flavonoids differentially modulate nitric oxide production pathways in lipopolysaccharide-activated RAW264.7 cells. Arch Pharm Res (2005) 0.94
Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide. Biochem Biophys Res Commun (2008) 0.94
Antiproliferative effect of resveratrol in human prostate carcinoma cells. J Med Food (2003) 0.94
Induction of endothelial apoptosis by 4-hydroxyhexenal. Eur J Biochem (2004) 0.94
Partial characterization and immunostimulatory effect of a novel polysaccharide-protein complex extracted from Phellinus linteus. Biosci Biotechnol Biochem (2006) 0.94
Polyphenols isolated from Allium cepa L. induces apoptosis by suppressing IAP-1 through inhibiting PI3K/Akt signaling pathways in human leukemic cells. Food Chem Toxicol (2013) 0.93
The histone demethylase JMJD1A regulates adrenomedullin-mediated cell proliferation in hepatocellular carcinoma under hypoxia. Biochem Biophys Res Commun (2013) 0.93
Modulation of glutathione and thioredoxin systems by calorie restriction during the aging process. Exp Gerontol (2003) 0.93