Published in Biochim Biophys Acta on September 09, 1992
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Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes. Nature (1987) 1.93
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A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor. Anal Biochem (1997) 1.47
The insulin receptor tyrosyl kinase phosphorylates holomeric forms of the guanine nucleotide regulatory proteins Gi and Go. FEBS Lett (1987) 1.46
The GTP-binding regulatory proteins of neuroblastoma x glioma, NG108-15, and glioma, C6, cells. Immunochemical evidence of a pertussis toxin substrate that is neither Ni nor No. FEBS Lett (1986) 1.45
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Bradykinin excites rat sympathetic neurons by inhibition of M current through a mechanism involving B2 receptors and G alpha q/11. Neuron (1995) 1.35
Immunochemical evidence for a novel pertussis toxin substrate in human neutrophils. J Biol Chem (1986) 1.33
Prostaglandin E1-mediated, cyclic AMP-independent, down-regulation of Gs alpha in neuroblastoma x glioma hybrid cells. J Biol Chem (1990) 1.33
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Antibodies against the carboxyl-terminal 5-kDa peptide of the alpha subunit of transducin crossreact with the 40-kDa but not the 39-kDa guanine nucleotide binding protein from brain. Proc Natl Acad Sci U S A (1985) 1.30
The alpha subunit of Gq contributes to muscarinic inhibition of the M-type potassium current in sympathetic neurons. J Neurosci (1998) 1.30
Down-regulation of Gi sub-types by prolonged incubation of adipocytes with an A1 adenosine receptor agonist. J Biol Chem (1990) 1.29
Development of opiate receptors and GTP-binding regulatory proteins in neonatal rat brain. J Biol Chem (1987) 1.29
Antiparkinsonian agent piribedil displays antagonist properties at native, rat, and cloned, human alpha(2)-adrenoceptors: cellular and functional characterization. J Pharmacol Exp Ther (2001) 1.28
Agonist activation of transfected human M1 muscarinic acetylcholine receptors in CHO cells results in down-regulation of both the receptor and the alpha subunit of the G-protein Gq. Biochem J (1993) 1.27
Diabetes-induced alterations in the expression, functioning and phosphorylation state of the inhibitory guanine nucleotide regulatory protein Gi-2 in hepatocytes. Biochem J (1990) 1.25
Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2. Proc Natl Acad Sci U S A (1992) 1.23
Purification of heterotrimeric GTP-binding proteins from brain: identification of a novel form of Go. Biochemistry (1988) 1.22
How reproducible is bilateral forearm plethysmography? Br J Clin Pharmacol (1998) 1.21
The G protein alpha subunit has a key role in determining the specificity of coupling to, but not the activation of, G protein-gated inwardly rectifying K(+) channels. J Biol Chem (2000) 1.20
A pH-sensitive fluor, CypHer 5, used to monitor agonist-induced G protein-coupled receptor internalization in live cells. Biotechniques (2002) 1.20
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Identification of two distinct isoforms of the guanine nucleotide binding protein G0 in neuroblastoma X glioma hybrid cells: independent regulation during cyclic AMP-induced differentiation. J Neurochem (1990) 1.18
Guanine nucleotide regulation of the pertussis and cholera toxin substrates of rat glioma C6 BU1 cells. Biochim Biophys Acta (1987) 1.15
Differential effects of suramin on the coupling of receptors to individual species of pertussis-toxin-sensitive guanine-nucleotide-binding proteins. Biochem J (1988) 1.13
Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. J Biol Chem (2000) 1.13
Detection of the major pertussis toxin substrate of human leukocytes with antisera raised against synthetic peptides. FEBS Lett (1986) 1.12
Widespread distribution of Gq alpha/G11 alpha detected immunologically by an antipeptide antiserum directed against the predicted C-terminal decapeptide. FEBS Lett (1991) 1.12
Treatment of intact hepatocytes with either the phorbol ester TPA or glucagon elicits the phosphorylation and functional inactivation of the inhibitory guanine nucleotide regulatory protein Gi. FEBS Lett (1989) 1.12
Endothelial nitric oxide production and insulin sensitivity. A physiological link with implications for pathogenesis of cardiovascular disease. Circulation (1996) 1.11
GTP analogues cause release of the alpha subunit of the GTP binding protein, GO, from the plasma membrane of NG108-15 cells. Biochem Biophys Res Commun (1988) 1.10
Functional control of the delta-opiate receptor by the inhibitory guanine nucleotide-binding protein. Biochem Soc Trans (1985) 1.10
Expression of 11beta-hydroxylase and aldosterone synthase genes in the rat brain. J Mol Endocrinol (2000) 1.09
Diabetes abolishes the GTP-dependent, but not the receptor-dependent inhibitory function of the inhibitory guanine-nucleotide-binding regulatory protein (Gi) on adipocyte adenylate cyclase activity. Biochem J (1990) 1.07
Apparent cortisone reductase deficiency: a functional defect in 11beta-hydroxysteroid dehydrogenase type 1. J Clin Endocrinol Metab (1999) 1.06
Gs alpha mediates epidermal growth factor-elicited stimulation of rat cardiac adenylate cyclase. J Biol Chem (1990) 1.05
Bone density and antiepileptic drugs: a case-controlled study. Seizure (1999) 1.05
Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) Zucker rats: loss of functional Gi and abnormal Gs function. Cell Signal (1989) 1.05
Interactions of the alpha2A-adrenoceptor with multiple Gi-family G-proteins: studies with pertussis toxin-resistant G-protein mutants. Biochem J (1997) 1.04
Differential regulation of amounts of the guanine-nucleotide-binding proteins Gi and Go in neuroblastoma x glioma hybrid cells in response to dibutyryl cyclic AMP. Biochem J (1988) 1.04
Immunological analysis of glucose transporters expressed in different regions of the rat brain and central nervous system. Biochem Biophys Res Commun (1993) 1.04
G-proteins and G-protein subunits mediating cholinergic inhibition of N-type calcium currents in sympathetic neurons. Eur J Neurosci (1998) 1.03
Mistyping of the human angiotensin-converting enzyme gene polymorphism: frequency, causes and possible methods to avoid errors in typing. J Mol Endocrinol (1996) 1.03
Effects of UK 69 578: a novel atriopeptidase inhibitor. Lancet (1989) 1.03
Inverse agonist-induced up-regulation of the human beta2-adrenoceptor in transfected neuroblastoma X glioma hybrid cells. Mol Pharmacol (1996) 1.03
Characteristics of males over 50 years who present with a fracture: epidemiology and underlying risk factors. J Bone Joint Surg Br (2008) 1.02
The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein. J Biol Chem (1987) 1.02
Molecular manipulation of G-protein-coupled receptors: a new avenue into drug discovery. Curr Med Chem (2000) 1.02
β-Arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II type 1A receptor stimulation. Mol Cell Biol (2010) 1.01
Distribution of G-proteins in rat liver plasma-membrane domains and endocytic pathways. Biochem J (1989) 1.01
Enhanced pressor response to angiotensin I in normotensive men with the deletion genotype (DD) for angiotensin-converting enzyme. Hypertension (1995) 1.01
Hydrophobicity of residue351 of the G protein Gi1 alpha determines the extent of activation by the alpha 2A-adrenoceptor. Biochemistry (1998) 1.00
Immunochemical and electrophoretic characterization of the major pertussis toxin substrate of the RAW264 macrophage cell line. Biochemistry (1988) 0.99
Influence of elevated plasma levels of atrial natriuretic factor on bronchial reactivity in asthma. Am Rev Respir Dis (1991) 0.99
Agonist-induced endocytosis and recycling of the gonadotropin-releasing hormone receptor: effect of beta-arrestin on internalization kinetics. Mol Endocrinol (1998) 0.99
Gi3 does not contribute to the inhibition of adenylate cyclase when stimulation of an alpha 2-adrenergic receptor causes activation of both Gi2 and Gi3. Biochem J (1992) 0.98
Familial pattern of corticosteroids and their metabolism in adult human subjects--the Scottish Adult Twin Study. J Clin Endocrinol Metab (1999) 0.98
A genome-wide screen in 1119 relative pairs with autoimmune thyroid disease. J Clin Endocrinol Metab (2005) 0.98
GPR35 as a Novel Therapeutic Target. Front Endocrinol (Lausanne) (2011) 0.98
Real time visualization of agonist-mediated redistribution and internalization of a green fluorescent protein-tagged form of the thyrotropin-releasing hormone receptor. J Biol Chem (1998) 0.98
5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. Diabetes (2000) 0.98
Peroxidase activity in relation to iodide, 17 beta-oestradiol and thioureylene drug uptake in human polymorphoneutrophils. Biochem Pharmacol (1984) 0.98
Visualizing differences in ligand regulation of wild-type and constitutively active mutant beta(2)-adrenoceptor-green fluorescent protein fusion proteins. Mol Pharmacol (1999) 0.98