PubRank

Michael M C Lai

Author PubWeight™ 90.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft. J Virol 2004 2.89
2 Hepatitis C virus RNA replication occurs on a detergent-resistant membrane that cofractionates with caveolin-2. J Virol 2003 2.86
3 Establishment of B-cell lymphoma cell lines persistently infected with hepatitis C virus in vivo and in vitro: the apoptotic effects of virus infection. J Virol 2003 2.60
4 Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins. Virology 2002 2.55
5 Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes. Proc Natl Acad Sci U S A 2004 2.30
6 Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts. Virology 2004 2.28
7 Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy. Hepatology 2003 2.14
8 Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B. J Virol 2005 1.86
9 Reactive oxygen species suppress hepatitis C virus RNA replication in human hepatoma cells. Hepatology 2004 1.71
10 Critical role of virion-associated cholesterol and sphingolipid in hepatitis C virus infection. J Virol 2008 1.65
11 Palmitoylation and polymerization of hepatitis C virus NS4B protein. J Virol 2006 1.59
12 Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proc Natl Acad Sci U S A 2006 1.59
13 Is avian influenza A (H7N9) virus staggering its way to humans? J Formos Med Assoc 2013 1.52
14 Hepatitis C virus triggers mitochondrial permeability transition with production of reactive oxygen species, leading to DNA damage and STAT3 activation. J Virol 2006 1.44
15 Association of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5A. J Virol 2008 1.43
16 Hepatitis C virus E2-CD81 interaction induces hypermutation of the immunoglobulin gene in B cells. J Virol 2005 1.40
17 Hepatitis C virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon and interleukin-6. J Virol 2006 1.38
18 Human monoclonal antibody to hepatitis C virus E1 glycoprotein that blocks virus attachment and viral infectivity. J Virol 2004 1.37
19 Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase. J Virol 2003 1.32
20 Ubiquitination and deubiquitination of NP protein regulates influenza A virus RNA replication. EMBO J 2010 1.30
21 Hepatitis C virus infection activates the immunologic (type II) isoform of nitric oxide synthase and thereby enhances DNA damage and mutations of cellular genes. J Virol 2004 1.30
22 The hepatitis C virus persistence: how to evade the immune system? J Biosci 2003 1.29
23 Rolling circle replication of hepatitis delta virus RNA is carried out by two different cellular RNA polymerases. J Virol 2002 1.28
24 Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy. J Virol 2011 1.27
25 High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity. Proc Natl Acad Sci U S A 2010 1.24
26 Detection of a novel unglycosylated form of hepatitis C virus E2 envelope protein that is located in the cytosol and interacts with PKR. J Virol 2002 1.22
27 Poly(C)-binding protein 2 interacts with sequences required for viral replication in the hepatitis C virus (HCV) 5' untranslated region and directs HCV RNA replication through circularizing the viral genome. J Virol 2011 1.21
28 c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair. Hepatology 2010 1.20
29 Hepatitis C virus proteins: direct link to hepatic oxidative stress, steatosis, carcinogenesis and more. Gastroenterology 2002 1.17
30 Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation. Virology 2007 1.16
31 Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes. J Immunol 2010 1.16
32 The ubiquitin-proteasome system facilitates the transfer of murine coronavirus from endosome to cytoplasm during virus entry. J Virol 2005 1.15
33 Hepatitis C virus infects T cells and affects interferon-gamma signaling in T cell lines. Virology 2006 1.14
34 Genomic but not antigenomic hepatitis delta virus RNA is preferentially exported from the nucleus immediately after synthesis and processing. J Virol 2002 1.10
35 Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A. J Virol 2010 1.09
36 Hepatitis delta virus antigen is methylated at arginine residues, and methylation regulates subcellular localization and RNA replication. J Virol 2004 1.08
37 Murine retroviral pseudotype virus containing hepatitis B virus large and small surface antigens confers specific tropism for primary human hepatocytes: a potential liver-specific targeting system. J Virol 2002 1.08
38 Polypyrimidine-tract-binding protein affects transcription but not translation of mouse hepatitis virus RNA. Virology 2002 1.08
39 Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase. Biochemistry 2003 1.06
40 Polypyrimidine-tract-binding protein is a component of the HCV RNA replication complex and necessary for RNA synthesis. J Biomed Sci 2006 1.06
41 Pooled RNAi screen identifies ubiquitin ligase Itch as crucial for influenza A virus release from the endosome during virus entry. Proc Natl Acad Sci U S A 2013 1.04
42 Hepatitis C virus (HCV)-induced immunoglobulin hypermutation reduces the affinity and neutralizing activities of antibodies against HCV envelope protein. J Virol 2008 1.03
43 The C-terminal transmembrane domain of hepatitis C virus (HCV) RNA polymerase is essential for HCV replication in vivo. J Virol 2004 1.03
44 Hepatitis C virus IRES-dependent translation is insensitive to an eIF2alpha-independent mechanism of inhibition by interferon in hepatocyte cell lines. Virology 2002 1.01
45 Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation. J Biol Chem 2002 1.00
46 Hepatitis C virus nonstructural 5B protein regulates tumor necrosis factor alpha signaling through effects on cellular IkappaB kinase. Mol Cell Biol 2006 1.00
47 Molecular pathogenesis of Gilbert's syndrome: decreased TATA-binding protein binding affinity of UGT1A1 gene promoter. Pharmacogenet Genomics 2007 1.00
48 Large hepatitis delta antigen is not a suppressor of hepatitis delta virus RNA synthesis once RNA replication is established. J Virol 2002 0.99
49 Hepatitis C virus egress and release depend on endosomal trafficking of core protein. J Virol 2010 0.98
50 Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft. J Virol 2012 0.97
51 RNA-templated replication of hepatitis delta virus: genomic and antigenomic RNAs associate with different nuclear bodies. J Virol 2006 0.97
52 SYNCRIP, a member of the heterogeneous nuclear ribonucleoprotein family, is involved in mouse hepatitis virus RNA synthesis. J Virol 2004 0.97
53 Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry. J Biol Chem 2012 0.97
54 Enzymatic characterization of the full-length and C-terminally truncated hepatitis C virus RNA polymerases: function of the last 21 amino acids of the C terminus in template binding and RNA synthesis. Biochemistry 2004 0.97
55 Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein. J Virol 2009 0.96
56 Murine coronavirus requires lipid rafts for virus entry and cell-cell fusion but not for virus release. J Virol 2005 0.96
57 Multiple type A/B heterogeneous nuclear ribonucleoproteins (hnRNPs) can replace hnRNP A1 in mouse hepatitis virus RNA synthesis. J Virol 2003 0.96
58 Treatment of HCV-related mantle-cell lymphoma with ribavirin and pegylated interferon Alfa. N Engl J Med 2003 0.95
59 Identification of RNA ligands that bind hepatitis C virus polymerase selectively and inhibit its RNA synthesis from the natural viral RNA templates. Virology 2003 0.94
60 SYNCRIP (synaptotagmin-binding, cytoplasmic RNA-interacting protein) is a host factor involved in hepatitis C virus RNA replication. Virology 2009 0.94
61 Hepatitis C virus genotype 1b core protein does not exert immunomodulatory effects on virus-induced cellular immunity. J Virol 2002 0.94
62 Modification of small hepatitis delta virus antigen by SUMO protein. J Virol 2009 0.92
63 Hepatitis C virus infection of T cells inhibits proliferation and enhances fas-mediated apoptosis by down-regulating the expression of CD44 splicing variant 6. J Infect Dis 2009 0.92
64 Hepatitis C virus causes uncoupling of mitotic checkpoint and chromosomal polyploidy through the Rb pathway. J Virol 2009 0.91
65 HCV core expression in hepatocytes protects against autoimmune liver injury and promotes liver regeneration in mice. Hepatology 2006 0.89
66 Transcription of subgenomic mRNA of hepatitis delta virus requires a modified hepatitis delta antigen that is distinct from antigenomic RNA synthesis. J Virol 2008 0.87
67 Redox modulation of the hepatitis C virus replication complex is calcium dependent. Free Radic Biol Med 2006 0.85
68 Hepatitis delta virus RNA replication. Viruses 2009 0.84
69 Proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2), a host membrane-deforming protein, is critical for membranous web formation in hepatitis C virus replication. J Virol 2011 0.83
70 Hepatitis delta virus RNA encoding the large delta antigen cannot sustain replication due to rapid accumulation of mutations associated with RNA editing. J Virol 2003 0.83
71 Hepatitis C virus core protein regulates p300/CBP co-activation function. Possible role in the regulation of NF-AT1 transcriptional activity. Virology 2004 0.83
72 Attenuation of 40S ribosomal subunit abundance differentially affects host and HCV translation and suppresses HCV replication. PLoS Pathog 2012 0.81
73 The 8ab protein of SARS-CoV is a luminal ER membrane-associated protein and induces the activation of ATF6. Virology 2009 0.81
74 Hepatitis C virus translation preferentially depends on active RNA replication. PLoS One 2012 0.80
75 Hepatitis delta virus RNA transfection for the cell culture model. Methods Mol Med 2004 0.75
76 Detection and characterization of small and large HDV antigens. Methods Mol Med 2004 0.75
77 [Hepatitis C virus replication associated with lipid rafts]. Seikagaku 2006 0.75