Published in Clin Immunol on July 01, 2004
The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis. J Immunol (2006) 2.83
Exacerbation of murine ileitis by Toll-like receptor 4 mediated sensing of lipopolysaccharide from commensal Escherichia coli. Gut (2007) 1.85
Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2. Gut (2005) 1.84
Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of Toll-like receptor 4 to hepatic stellate cell responses. Hepatology (2009) 1.72
Role of the intestinal barrier in inflammatory bowel disease. World J Gastroenterol (2008) 1.72
Role of Toll-like receptors in gastrointestinal malignancies. Oncogene (2008) 1.69
Toll-like receptor 3 gene polymorphisms in Japanese patients with Stevens-Johnson syndrome. Br J Ophthalmol (2007) 1.53
Inflammatory bowel disease: review from the aspect of genetics. J Gastroenterol (2009) 1.51
A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis. Am J Physiol Gastrointest Liver Physiol (2009) 1.39
Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population. World J Gastroenterol (2005) 1.38
Wound healing of intestinal epithelial cells. World J Gastroenterol (2011) 1.35
Pathogen recognition receptors, cancer and inflammation in the gut. Curr Opin Pharmacol (2009) 1.14
DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population. Gut (2005) 1.12
CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations. Eur J Cancer Prev (2009) 1.07
Cellular and molecular mechanisms of intestinal fibrosis. World J Gastroenterol (2012) 1.07
Role of Toll-like receptors in health and diseases of gastrointestinal tract. World J Gastroenterol (2006) 1.06
Toll-like receptor (TLR) 4 polymorphisms are associated with a chronic course of sarcoidosis. Clin Exp Immunol (2006) 1.06
Future biologic targets for IBD: potentials and pitfalls. Nat Rev Gastroenterol Hepatol (2010) 1.06
TLR4 polymorphisms and disease susceptibility. Inflamm Res (2012) 1.05
Inflammatory bowel disease: genetic and epidemiologic considerations. World J Gastroenterol (2008) 1.03
Association between CD14 gene C-260T polymorphism and inflammatory bowel disease: a meta-analysis. PLoS One (2012) 1.00
Novel genetic markers in inflammatory bowel disease. World J Gastroenterol (2007) 0.99
Clinical significance of NOD2/CARD15 and Toll-like receptor 4 gene single nucleotide polymorphisms in inflammatory bowel disease. World J Gastroenterol (2008) 0.98
Macrophage migration inhibitory factor contributes to the development of acute dextran sulphate sodium-induced colitis in Toll-like receptor 4 knockout mice. Clin Exp Immunol (2005) 0.98
Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs. PLoS One (2010) 0.98
Polymorphisms in genes related to bacterial lipopolysaccharide/peptidoglycan signaling and gastric precancerous lesions in a population at high risk for gastric cancer. Dig Dis Sci (2006) 0.97
Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15(-) Crohn's disease patients. Eur J Hum Genet (2009) 0.96
Association of TLR4-T399I polymorphism with chronic obstructive pulmonary disease in smokers. Clin Dev Immunol (2010) 0.94
Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers. Onco Targets Ther (2013) 0.94
Intestinal microbiota, probiotics and prebiotics in inflammatory bowel disease. World J Gastroenterol (2014) 0.92
Polymorphisms of CD14 gene and TLR4 gene are not associated with ulcerative colitis in Chinese patients. Postgrad Med J (2005) 0.92
Patients with inflammatory bowel disease exhibit dysregulated responses to microbial DNA. PLoS One (2012) 0.90
Toll-like receptor 4 gene (TLR4), but not TLR2, polymorphisms modify the risk of tonsillar disease due to Streptococcus pyogenes and Haemophilus influenzae. Clin Vaccine Immunol (2010) 0.89
A TLR4-interacting peptide inhibits lipopolysaccharide-stimulated inflammatory responses, migration and invasion of colon cancer SW480 cells. Oncoimmunology (2012) 0.89
Toll-like receptor 4 gene in IBD: further evidence for genetic heterogeneity in Europe. Gut (2005) 0.87
Toll-like receptors in inflammatory bowel disease-stepping into uncharted territory. World J Gastroenterol (2008) 0.86
Association between TLR2 and TLR4 Gene Polymorphisms and the Susceptibility to Inflammatory Bowel Disease: A Meta-Analysis. PLoS One (2015) 0.85
Tolllike receptor 4 (TLR4) polymorphisms in Tunisian patients with Crohn's disease: genotype-phenotype correlation. BMC Gastroenterol (2009) 0.84
Analysis of TLR4 and TLR2 polymorphisms in inflammatory bowel disease in a Guangxi Zhuang population. World J Gastroenterol (2012) 0.83
Readressing the role of Toll-like receptor-4 alleles in inflammatory bowel disease: colitis, smoking, and seroreactivity. Dig Dis Sci (2012) 0.82
Dendritic cells and toll-like receptors 2 and 4 in the ileum of Crohn's disease patients. Dig Dis Sci (2007) 0.82
TLR4 mutations (Asp299Gly and Thr399Ile) are not associated with ankylosing spondylitis. Ann Rheum Dis (2006) 0.81
Novel susceptibility genes in inflammatory bowel disease. World J Gastroenterol (2006) 0.81
Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms: New data and a meta-analysis. BMC Gastroenterol (2014) 0.81
CARD15/NOD2, CD14 and toll-like 4 receptor gene polymorphisms in Saudi patients with Crohn's Disease. Int J Mol Sci (2012) 0.81
Differential expression of TLR2, TLR4 and JNK in mucosa of ileal pouches for ulcerative colitis. Is there a role for bacterial antigen pathway in asymptomatic patients? Int J Clin Exp Med (2011) 0.80
Bactericidal permeability increasing protein gene polymorphism is associated with inflammatory bowel diseases in the Turkish population. Saudi J Gastroenterol (2015) 0.80
Association of NOD1, CXCL16, STAT6 and TLR4 gene polymorphisms with Malaysian patients with Crohn's disease. PeerJ (2016) 0.78
Effect of RANTES gene promoter genotypes in patients with ulcerative colitis. Biomed Rep (2014) 0.78
Analysis of single nucleotide polymorphisms in Toll-like receptor 4 shows no association with ankylosing spondylitis in a Korean population. Rheumatol Int (2007) 0.77
Clustering of (auto)immune diseases with early-onset and complicated inflammatory bowel disease. Eur J Pediatr (2008) 0.77
Common NOD2/CARD15 and TLR4 Polymorphisms Are Associated with Crohn's Disease Phenotypes in Southeastern Brazilians. Dig Dis Sci (2016) 0.77
Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature. World J Gastrointest Pathophysiol (2014) 0.76
Functional Toll-Like Receptor (TLR)2 polymorphisms in the susceptibility to inflammatory bowel disease. PLoS One (2017) 0.75
Role of TLR4 rs4986790A>G and rs4986791C>T Polymorphisms in the Risk of Inflammatory Bowel Disease. Gastroenterol Res Pract (2015) 0.75
Heat-shock protein 70-2 BB genotype is associated with reduced risks of the steroid-dependent and refractory phenotypes of ulcerative colitis. Biomed Rep (2014) 0.75
Novel perspectives on non-canonical inflammasome activation. Immunotargets Ther (2015) 0.75
Bactericidal/permeability increasing protein gene polymorphism and inflammatory bowel diseases: meta-analysis of five case-control studies. Int J Colorectal Dis (2016) 0.75
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet (2011) 7.98
Evidence for two types of brown adipose tissue in humans. Nat Med (2013) 2.97
Laparoscopic versus open adrenalectomy for adrenocortical carcinoma: surgical and oncologic outcome in 152 patients. Eur Urol (2010) 2.49
Polymorphisms in melanoma differentiation-associated gene 5 link protein function to clearance of hepatitis C virus. Hepatology (2015) 2.11
Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD. Inflamm Bowel Dis (2008) 1.96
Adherence and mental side effects during hepatitis C treatment with interferon alfa and ribavirin in psychiatric risk groups. Hepatology (2003) 1.86
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies. Gastroenterology (2013) 1.83
Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease. Am J Gastroenterol (2009) 1.80
Allele 2 of the interleukin-1 receptor antagonist gene is associated with early gastric cancer. J Clin Oncol (2004) 1.70
Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status. Inflamm Bowel Dis (2008) 1.64
Crohn's disease is associated with a toll-like receptor-9 polymorphism. Gastroenterology (2004) 1.55
Bilateral primary adrenal non-Hodgkin's lymphoma and primary adrenocortical carcinoma--review of the literature preoperative differentiation of adrenal tumors. Endocr J (2008) 1.54
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. PLoS One (2007) 1.48
Intraoperative laparoscope augmentation for port placement and resection planning in minimally invasive liver resection. IEEE Trans Med Imaging (2008) 1.33
Pneumopericardium in blunt chest trauma after high-speed motor vehicle accidents. Am J Emerg Med (2005) 1.30
Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis. Am J Gastroenterol (2010) 1.20
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Am J Gastroenterol (2007) 1.18
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis. Nat Genet (2013) 1.11
Heavy-weight versus low-weight polypropylene meshes for open sublay mesh repair of incisional hernia. Eur J Med Res (2005) 1.07
Crohn's disease: an immunodeficiency? Eur J Gastroenterol Hepatol (2003) 1.06
A polymorphism of the NFKBIA gene is associated with Crohn's disease patients lacking a predisposing allele of the CARD15 gene. Int J Colorectal Dis (2003) 1.05
Endovascular aneurysm repair: Treatment of choice for abdominal aortic aneurysm coincident with horseshoe kidney? Three case reports and review of literature. J Vasc Surg (2004) 1.03
Prolonged zona glomerulosa insufficiency causing hyperkalemia in primary aldosteronism after adrenalectomy. J Clin Endocrinol Metab (2012) 0.99
NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes. Inflamm Bowel Dis (2008) 0.97
Strong overexpression of CXCR3 axis components in childhood inflammatory bowel disease. Inflamm Bowel Dis (2010) 0.95
Functional cine MRI of the abdomen for the assessment of implanted synthetic mesh in patients after incisional hernia repair: initial results. Eur Radiol (2007) 0.95
Intrathecal and systemic concentration of NT-proBNP in patients with severe traumatic brain injury. J Neurotrauma (2006) 0.94
Polymorphisms of the interleukin-18 gene in periodontitis patients. J Clin Periodontol (2005) 0.92
Cytotoxic and genotoxic effects of resin monomers in human salivary gland tissue and lymphocytes as assessed by the single cell microgel electrophoresis (Comet) assay. Biomaterials (2005) 0.92
Association of polymorphisms in the interleukin-18 gene in patients with Crohn's disease depending on the CARD15/NOD2 genotype. Inflamm Bowel Dis (2005) 0.90
rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. Am J Gastroenterol (2009) 0.90
Alterations of the CARD15/NOD2 gene and the impact on management and treatment of Crohn's disease patients. Dig Dis (2003) 0.89
Clinical management of large adrenal cystic lesions. Int Urol Nephrol (2005) 0.89
Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status. Inflamm Bowel Dis (2015) 0.89
Presence of brown adipocytes in retroperitoneal fat from patients with benign adrenal tumors: relationship with outdoor temperature. J Clin Endocrinol Metab (2013) 0.88
The angiotensin I-converting enzyme gene insertion/deletion polymorphism is linked to early gastric cancer. Cancer Epidemiol Biomarkers Prev (2005) 0.88
Dendritic cell-based vaccination of patients with advanced pancreatic carcinoma: results of a pilot study. Cancer Immunol Immunother (2011) 0.87
Preoperative serum levels of the carcinoembryonic antigen in hereditary non-polyposis colorectal cancer compared to levels in sporadic colorectal cancer. Cancer Detect Prev (2005) 0.86
Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease. Clin Immunol (2008) 0.86
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype. J Gastroenterol (2010) 0.85
Novel role of toll-like receptor 3, RIG-I and MDA5 in poly (I:C) RNA-induced mesothelial inflammation. Mol Cell Biochem (2008) 0.85
MDR1 gene polymorphism in ulcerative colitis. Gastroenterology (2004) 0.84
Cyanoacrylate glue for intra-abdominal mesh fixation of polypropylene-polyvinylidene fluoride meshes in a rabbit model. J Surg Res (2009) 0.84
Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes. Inflamm Bowel Dis (2006) 0.83
The 14-bp deletion polymorphism in the HLA-G gene displays significant differences between ulcerative colitis and Crohn's disease and is associated with ileocecal resection in Crohn's disease. Int Immunol (2007) 0.83
The LMP7-K allele of the immunoproteasome exhibits reduced transcript stability and predicts high risk of colon cancer. Cancer Res (2011) 0.82
A polymorphism of the bactericidal/permeability increasing protein (BPI) gene is associated with Crohn's disease. J Clin Gastroenterol (2005) 0.82
Role of viral induced vascular endothelial growth factor (VEGF) production in pleural effusion and malignant mesothelioma. Cell Biol Int (2008) 0.81
The -2518 promotor polymorphism in the MCP-1 gene is not associated with liver cirrhosis in chronic hepatitis C virus infection. Gastroenterology (2004) 0.81
Cell death effects of resin-based dental material compounds and mercurials in human gingival fibroblasts. Arch Toxicol (2005) 0.81
ACE inhibitor and AT1-receptor blocker attenuate the production of VEGF in mesothelial cells. Perit Dial Int (2007) 0.81
Long term outcome and quality of life after open incisional hernia repair--light versus heavy weight meshes. BMC Surg (2011) 0.81
Liposomal polychemotherapy improves adrenocortical carcinoma treatment in a preclinical rodent model. Endocr Relat Cancer (2014) 0.80
Assessment of colonic transit time using MRI: a feasibility study. Eur Radiol (2006) 0.80
The leukocyte count predicts the efficacy of treatment with azathioprine in inflammatory bowel disease. Eur J Med Res (2005) 0.80
Role of PPARG gene variants in inflammatory bowel disease. Inflamm Bowel Dis (2010) 0.80
Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2. PLoS One (2013) 0.79
Successful treatment of cervical esophageal perforation in Behcet's disease with drainage operation and infliximab. Am J Gastroenterol (2003) 0.78
Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease. J Clin Periodontol (2004) 0.78
Genetic variants and the risk of Crohn's disease: what does it mean for future disease management? Expert Opin Pharmacother (2006) 0.78
The CD14 -159C-to-T promoter polymorphism in periodontal disease. J Clin Periodontol (2004) 0.78
Analysis of IL2/IL21 gene variants in cholestatic liver diseases reveals an association with primary sclerosing cholangitis. Digestion (2011) 0.78
Effect of activation of viral receptors on the gelatinases MMP-2 and MMP-9 in human mesothelial cells. Matrix Biol (2009) 0.78
Lack of influence of somatic mutations on steroid gradients during adrenal vein sampling in aldosterone-producing adenoma patients. Eur J Endocrinol (2013) 0.77
Role of toll-like receptor 3, RIG-I, and MDA5 in the expression of mesothelial IL-8 induced by viral RNA. Appl Biochem Biotechnol (2009) 0.77
Etoricoxib--preemptive and postoperative analgesia (EPPA) in patients with laparotomy or thoracotomy--design and protocols. Trials (2010) 0.77
PAR-1 mediates the thrombin-induced mesothelial cell overproduction of VEGF and PAI-1. Int J Artif Organs (2013) 0.77
The 3020insC mutation of the NOD2/CARD15 gene in patients with periodontal disease. Eur J Oral Sci (2004) 0.77
Prevalence of the chemokine receptor CCR5-Delta32 gene mutation in periodontal disease. Clin Immunol (2003) 0.77