Published in Cytokine Growth Factor Rev on August 01, 2004
Role of platelet-derived growth factors in physiology and medicine. Genes Dev (2008) 8.89
PDGFRbeta+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival. Nat Cell Biol (2005) 4.57
The role of pericytes in blood-vessel formation and maintenance. Neuro Oncol (2005) 4.54
Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors. Nat Rev Cancer (2010) 3.48
Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells. J Clin Invest (2010) 3.09
An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA. Dev Cell (2014) 2.89
Vascular endothelial growth factor in eye disease. Prog Retin Eye Res (2008) 2.73
Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice. Proc Natl Acad Sci U S A (2008) 2.06
Small-diameter human vessel wall engineered from bone marrow-derived mesenchymal stem cells (hMSCs). FASEB J (2008) 1.97
Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function. PLoS Biol (2007) 1.92
Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer. Am J Pathol (2009) 1.81
Tie2 activation contributes to hemangiogenic regeneration after myelosuppression. Blood (2005) 1.73
Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J Cell Biol (2007) 1.71
Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing. Am J Pathol (2006) 1.70
Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development. Genes Dev (2007) 1.68
Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression. Blood (2011) 1.66
Essential role for STIM1/Orai1-mediated calcium influx in PDGF-induced smooth muscle migration. Am J Physiol Cell Physiol (2010) 1.58
The role played by perivascular cells in kidney interstitial injury. Clin Nephrol (2012) 1.49
PDGF and PDGF receptors in glioma. Ups J Med Sci (2012) 1.43
Genetic variations in angiopoietin and pericyte pathways and clinical outcome in patients with resected colorectal liver metastases. Cancer (2015) 1.42
Pericyte migration: a novel mechanism of pericyte loss in experimental diabetic retinopathy. Diabetes (2008) 1.36
Mesenchymal stem cells and neovascularization: role of platelet-derived growth factor receptors. J Cell Mol Med (2007) 1.33
Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD. Nat Rev Nephrol (2015) 1.24
A phase II study of pazopanib in patients with recurrent or metastatic invasive breast carcinoma: a trial of the Princess Margaret Hospital phase II consortium. Oncologist (2010) 1.22
Osteoclasts control osteoblast chemotaxis via PDGF-BB/PDGF receptor beta signaling. PLoS One (2008) 1.20
Wnt2 signaling is necessary and sufficient to activate the airway smooth muscle program in the lung by regulating myocardin/Mrtf-B and Fgf10 expression. Dev Biol (2011) 1.19
Mesenchymal cell survival in airway and interstitial pulmonary fibrosis. Fibrogenesis Tissue Repair (2010) 1.17
SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans. J Clin Invest (2011) 1.16
Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1). EMBO J (2007) 1.10
Relationship between interstitial cells of Cajal, fibroblast-like cells and inhibitory motor nerves in the internal anal sphincter. Cell Tissue Res (2011) 1.09
Distribution and possible role of PDGF-AA and PDGFR-alpha in the gastrointestinal tract of adult guinea pigs. Virchows Arch (2010) 1.06
Fibronectin growth factor-binding domains are required for fibroblast survival. J Invest Dermatol (2010) 1.02
Combination therapy targeting the tumor microenvironment is effective in a model of human ocular melanoma. J Transl Med (2007) 1.02
Tyrosine kinases as targets for the treatment of rheumatoid arthritis. Nat Rev Rheumatol (2009) 1.01
A review on angiogenesis and its assays. Iran J Basic Med Sci (2012) 1.00
Capillary defects and exaggerated inflammatory response in the airways of EphA2-deficient mice. Am J Pathol (2009) 1.00
The absence of platelet-derived growth factor-B in circulating cells promotes immune and inflammatory responses in atherosclerosis-prone ApoE-/- mice. Am J Pathol (2005) 0.99
Neuraminidase-1, a subunit of the cell surface elastin receptor, desialylates and functionally inactivates adjacent receptors interacting with the mitogenic growth factors PDGF-BB and IGF-2. Am J Pathol (2008) 0.99
Molecular pathogenesis of retinal and choroidal vascular diseases. Prog Retin Eye Res (2015) 0.99
The role of pericyte detachment in vascular rarefaction. J Vasc Res (2014) 0.98
Molecular mediators of angiogenesis. J Burn Care Res (2010) 0.98
Influence of morphine on pericyte-endothelial interaction: implications for antiangiogenic therapy. J Oncol (2012) 0.98
PDGF receptor-α promotes TGF-β signaling in hepatic stellate cells via transcriptional and posttranscriptional regulation of TGF-β receptors. Am J Physiol Gastrointest Liver Physiol (2014) 0.95
Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivo. Am J Pathol (2009) 0.95
Platelet-derived growth factor receptor beta is critical for zebrafish intersegmental vessel formation. PLoS One (2010) 0.94
Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions. Genes Dev (2014) 0.94
Regulation of vascular integrity. J Mol Med (Berl) (2009) 0.92
PDGF-Ralpha gene expression predicts proliferation, but PDGF-A suppresses transdifferentiation of neonatal mouse lung myofibroblasts. Respir Res (2009) 0.91
Fibronectin peptides that bind PDGF-BB enhance survival of cells and tissue under stress. J Invest Dermatol (2013) 0.91
Pericyte-endothelial crosstalk: implications and opportunities for advanced cellular therapies. Transl Res (2014) 0.90
Platelet-derived growth factor receptor alpha in glioma: a bad seed. Chin J Cancer (2011) 0.89
Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis. Kidney Int (2011) 0.88
Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration. Pflugers Arch (2012) 0.88
Implication of platelet-derived growth factor receptor alpha in prostate cancer skeletal metastasis. Chin J Cancer (2011) 0.87
Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β. Pulm Circ (2011) 0.87
Brain abnormalities and glioma-like lesions in mice overexpressing the long isoform of PDGF-A in astrocytic cells. PLoS One (2011) 0.85
A differential role for CD248 (Endosialin) in PDGF-mediated skeletal muscle angiogenesis. PLoS One (2014) 0.84
Intertwined regulation of angiogenesis and immunity by myeloid cells. Trends Immunol (2015) 0.84
Angiogenic therapy for cardiac repair based on protein delivery systems. Heart Fail Rev (2012) 0.83
The Semaphorin 4D-Plexin-B1-RhoA signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B and ANGPTL4. Angiogenesis (2013) 0.83
Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients. J Transl Med (2011) 0.83
Integral role of platelet-derived growth factor in mediating transforming growth factor-β1-dependent mesenchymal stem cell stiffening. Stem Cells Dev (2013) 0.83
Targeted treatment for advanced soft tissue sarcoma: profile of pazopanib. Onco Targets Ther (2013) 0.82
Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling. BMC Cancer (2014) 0.82
PDGFRβ expression and function in fibroblasts derived from pluripotent cells is linked to DNA demethylation. J Cell Sci (2012) 0.81
Brain and Retinal Pericytes: Origin, Function and Role. Front Cell Neurosci (2016) 0.81
Platelet-Derived Growth Factor (PDGF)/PDGF Receptors (PDGFR) Axis as Target for Antitumor and Antiangiogenic Therapy. Pharmaceuticals (Basel) (2010) 0.81
Implementing neuronal plasticity in NeuroAIDS: the experience of brain-derived neurotrophic factor and other neurotrophic factors. J Neuroimmune Pharmacol (2013) 0.81
Identification of platelet-derived growth factor D in human chronic allograft nephropathy. Hum Pathol (2008) 0.81
Sequential delivery of angiogenic growth factors improves revascularization and heart function after myocardial infarction. J Control Release (2015) 0.81
Platelet-derived growth factor C deficiency in C57BL/6 mice leads to abnormal cerebral vascularization, loss of neuroependymal integrity, and ventricular abnormalities. Am J Pathol (2012) 0.80
Critical roles for murine Reck in the regulation of vascular patterning and stabilization. Sci Rep (2015) 0.80
Platelet-derived growth factor receptor-beta, carrying the activating mutation D849N, accelerates the establishment of B16 melanoma. BMC Cancer (2007) 0.80
Receptor tyrosine kinase inhibitors AG013764 and AG013711 reduce choroidal neovascularization in rat eye. Exp Eye Res (2007) 0.80
A synthetic dsRNA, as a TLR3 pathwaysynergist, combined with sorafenib suppresses HCC in vitro and in vivo. BMC Cancer (2013) 0.79
Platelet-Derived Growth Factors in Non-GIST Soft-Tissue Sarcomas Identify a Subgroup of Patients with Wide Resection Margins and Poor Disease-Specific Survival. Sarcoma (2011) 0.79
Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development (2015) 0.78
Protrusion-localized STAT3 mRNA promotes metastasis of highly metastatic hepatocellular carcinoma cells in vitro. Acta Pharmacol Sin (2016) 0.77
Inhibition of Wnt/β-catenin signaling suppresses bleomycin-induced pulmonary fibrosis by attenuating the expression of TGF-β1 and FGF-2. Exp Mol Pathol (2016) 0.77
The platelet-derived growth factor signaling system in snapping turtle embryos, Chelydra serpentina: potential role in temperature-dependent sex determination and testis development. Gen Comp Endocrinol (2009) 0.77
Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option? Biol Res (2014) 0.76
Quantitative Phosphoproteomics Reveals a Role for Collapsin Response Mediator Protein 2 in PDGF-Induced Cell Migration. Sci Rep (2017) 0.75
Pharmacological targeting of the PDGF-CC signaling pathway for blood-brain barrier restoration in neurological disorders. Pharmacol Ther (2016) 0.75
Vasoregression: A Shared Vascular Pathology Underlying Macrovascular And Microvascular Pathologies? OMICS (2015) 0.75
Platelet derived growth factor inhibitors: A potential therapeutic approach for ocular neovascularization. Saudi J Ophthalmol (2015) 0.75
Imatinib for highly chemoresistant Kaposi sarcoma in a patient with long-term HIV control: a case report and literature review. Curr Oncol (2015) 0.75