Published in Cytokine Growth Factor Rev on August 01, 2004
Role of platelet-derived growth factors in physiology and medicine. Genes Dev (2008) 8.89
The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease. Cell Death Differ (2009) 3.43
Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload. J Clin Invest (2009) 2.46
Transglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cells. Circ Res (2008) 2.19
Small-diameter human vessel wall engineered from bone marrow-derived mesenchymal stem cells (hMSCs). FASEB J (2008) 1.97
Redox control of the cell cycle in health and disease. Antioxid Redox Signal (2009) 1.72
Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia. Circ Res (2013) 1.68
Essential role for STIM1/Orai1-mediated calcium influx in PDGF-induced smooth muscle migration. Am J Physiol Cell Physiol (2010) 1.58
The NR4A orphan nuclear receptor NOR1 is induced by platelet-derived growth factor and mediates vascular smooth muscle cell proliferation. J Biol Chem (2006) 1.48
Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression. Breast Cancer Res (2005) 1.47
PDGFRβ signaling regulates mural cell plasticity and inhibits fat development. Dev Cell (2011) 1.45
Mesenchymal stem cells and neovascularization: role of platelet-derived growth factor receptors. J Cell Mol Med (2007) 1.33
Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle. Am J Physiol Heart Circ Physiol (2009) 1.32
Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells. Free Radic Biol Med (2008) 1.27
Wild-type LRP6 inhibits, whereas atherosclerosis-linked LRP6R611C increases PDGF-dependent vascular smooth muscle cell proliferation. Proc Natl Acad Sci U S A (2011) 1.24
MicroRNA-638 is highly expressed in human vascular smooth muscle cells and inhibits PDGF-BB-induced cell proliferation and migration through targeting orphan nuclear receptor NOR1. Cardiovasc Res (2013) 1.21
Unexpected role of the copper transporter ATP7A in PDGF-induced vascular smooth muscle cell migration. Circ Res (2010) 1.12
Bone marrow-derived MCP1 required for experimental aortic aneurysm formation and smooth muscle phenotypic modulation. J Thorac Cardiovasc Surg (2011) 1.11
Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells. Biochem J (2010) 1.07
A CXCL5- and bFGF-dependent effect of PDGF-B-activated fibroblasts in promoting trafficking and differentiation of bone marrow-derived mesenchymal stem cells. Exp Cell Res (2008) 1.05
NADPH oxidase 4 mediates monocyte priming and accelerated chemotaxis induced by metabolic stress. Arterioscler Thromb Vasc Biol (2011) 1.05
Effect of substrate stiffness and PDGF on the behavior of vascular smooth muscle cells: implications for atherosclerosis. J Cell Physiol (2010) 1.02
Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway. Hum Mol Genet (2008) 1.01
Vinpocetine suppresses pathological vascular remodeling by inhibiting vascular smooth muscle cell proliferation and migration. J Pharmacol Exp Ther (2012) 0.99
Neuraminidase-1, a subunit of the cell surface elastin receptor, desialylates and functionally inactivates adjacent receptors interacting with the mitogenic growth factors PDGF-BB and IGF-2. Am J Pathol (2008) 0.99
The absence of platelet-derived growth factor-B in circulating cells promotes immune and inflammatory responses in atherosclerosis-prone ApoE-/- mice. Am J Pathol (2005) 0.99
Sulfur dioxide inhibits vascular smooth muscle cell proliferation via suppressing the Erk/MAP kinase pathway mediated by cAMP/PKA signaling. Cell Death Dis (2014) 0.99
PDGF-induced proliferation in human arterial and venous smooth muscle cells: molecular basis for differential effects of PDGF isoforms. J Cell Biochem (2011) 0.96
Cell-cell interactions mediate the response of vascular smooth muscle cells to substrate stiffness. Biophys J (2011) 0.95
IQGAP1 links PDGF receptor-β signal to focal adhesions involved in vascular smooth muscle cell migration: role in neointimal formation after vascular injury. Am J Physiol Cell Physiol (2013) 0.92
Adipocytokines in atherothrombosis: focus on platelets and vascular smooth muscle cells. Mediators Inflamm (2010) 0.90
Dysfunctional, pro-inflammatory HDL directly upregulates monocyte PDGFRβ, chemotaxis and TNFα production. Clin Immunol (2010) 0.89
Proliferative capacity of vein graft smooth muscle cells and fibroblasts in vitro correlates with graft stenosis. J Vasc Surg (2009) 0.88
Kruppel-like factor 15 is critical for vascular inflammation. J Clin Invest (2013) 0.87
PPARgamma as a potential therapeutic target in pulmonary hypertension. Ther Adv Respir Dis (2010) 0.87
Substrate Stiffness Regulates PDGF-Induced Circular Dorsal Ruffle Formation Through MLCK. Cell Mol Bioeng (2013) 0.87
Phospholipase C signaling and calcium influx. Adv Biol Regul (2012) 0.86
Role of coronin 1B in PDGF-induced migration of vascular smooth muscle cells. Circ Res (2012) 0.85
Copper Transport Protein Antioxidant-1 Promotes Inflammatory Neovascularization via Chaperone and Transcription Factor Function. Sci Rep (2015) 0.84
Increased myosin light chain kinase expression in hypertension: Regulation by serum response factor via an insertion mutation in the promoter. Mol Biol Cell (2006) 0.84
Atherosclerosis susceptibility Loci identified in an extremely atherosclerosis-resistant mouse strain. J Am Heart Assoc (2013) 0.84
Plasma BDNF and PDGF-AA levels are associated with high TCD velocity and stroke in children with sickle cell anemia. Cytokine (2012) 0.84
Ephrin-B2 controls PDGFRβ internalization and signaling. Genes Dev (2013) 0.84
Ovarian wedge resection restores fertility in estrogen receptor beta knockout (ERbeta-/-) mice. Proc Natl Acad Sci U S A (2006) 0.84
Reduction of endoplasmic reticulum stress inhibits neointima formation after vascular injury. Sci Rep (2014) 0.84
Lycopene binding compromised PDGF-AA/-AB signaling and migration in smooth muscle cells and fibroblasts: prediction of the possible lycopene binding site within PDGF. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.84
PDGFRβ signalling regulates local inflammation and synergizes with hypercholesterolaemia to promote atherosclerosis. Nat Commun (2015) 0.83
Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease. Arterioscler Thromb Vasc Biol (2015) 0.83
PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality. Am J Physiol Cell Physiol (2011) 0.83
Tissue transglutaminase promotes PDGF/PDGFR-mediated signaling and responses in vascular smooth muscle cells. J Cell Physiol (2012) 0.83
History of discovery: platelet-derived growth factor. Arterioscler Thromb Vasc Biol (2011) 0.82
Mechanical stretch increases MMP-2 production in vascular smooth muscle cells via activation of PDGFR-β/Akt signaling pathway. PLoS One (2013) 0.82
Interaction between insulin-like growth factor-1 and atherosclerosis and vascular aging. Front Horm Res (2014) 0.81
A naturally occurring carotenoid, lutein, reduces PDGF and H₂O₂ signaling and compromised migration in cultured vascular smooth muscle cells. J Biomed Sci (2012) 0.81
Identification of platelet-derived growth factor D in human chronic allograft nephropathy. Hum Pathol (2008) 0.81
Bisdemethoxycurcumin inhibits PDGF-induced vascular smooth muscle cell motility and proliferation. Mol Nutr Food Res (2013) 0.81
Therapeutic effects of water soluble danshen extracts on atherosclerosis. Evid Based Complement Alternat Med (2013) 0.80
Disruption of platelet-derived growth factor-dependent phosphatidylinositol 3-kinase and phospholipase Cγ 1 activity abolishes vascular smooth muscle cell proliferation and migration and attenuates neointima formation in vivo. J Am Coll Cardiol (2011) 0.80
Mathematical modeling of collagen turnover in biological tissue. J Math Biol (2012) 0.80
The matricellular protein Cyr61 is a key mediator of platelet-derived growth factor-induced cell migration. J Biol Chem (2015) 0.80
A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents. Am J Respir Crit Care Med (2012) 0.79
Transglutaminase 2 promotes PDGF-mediated activation of PDGFR/Akt1 and β-catenin signaling in vascular smooth muscle cells and supports neointima formation. J Vasc Res (2015) 0.79
Novel role of copper transport protein antioxidant-1 in neointimal formation after vascular injury. Arterioscler Thromb Vasc Biol (2013) 0.79
A Novel Approach against Vascular Intimal Hyperplasia Through the Suppression of Girdin. Ann Vasc Dis (2015) 0.79
Anti-Restenotic Roles of Dihydroaustrasulfone Alcohol Involved in Inhibiting PDGF-BB-Stimulated Proliferation and Migration of Vascular Smooth Muscle Cells. Mar Drugs (2015) 0.78
Retracted Injury-induced platelet-derived growth factor receptor-alpha expression mediated by interleukin-1beta (IL-1beta) release and cooperative transactivation by NF-kappaB and ATF-4: IL-1beta facilitates HDAC-1/2 dissociation from promoter. J Biol Chem (2009) 0.78
Blockade of Ets-1 attenuates epidermal growth factor-dependent collagen loss in human carotid plaque smooth muscle cells. Am J Physiol Heart Circ Physiol (2015) 0.78
Krüppel-like factor 4 is induced by rapamycin and mediates the anti-proliferative effect of rapamycin in rat carotid arteries after balloon injury. Br J Pharmacol (2012) 0.78
Serum ADMA concentration-- an independent factor determining FMD impairment in cardiac syndrome X. Ups J Med Sci (2009) 0.78
Orai channel-mediated Ca2+ signals in vascular and airway smooth muscle. Am J Physiol Cell Physiol (2015) 0.78
Retracted Histone deacetylase-1 is enriched at the platelet-derived growth factor-D promoter in response to interleukin-1beta and forms a cytokine-inducible gene-silencing complex with NF-kappab p65 and interferon regulatory factor-1. J Biol Chem (2009) 0.78
Role of PDGFs/PDGFRs signaling pathway in myocardial fibrosis of DOCA/salt hypertensive rats. Int J Clin Exp Pathol (2013) 0.78
Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury. Int J Mol Med (2015) 0.77
Effects of external wrapping and increased blood flow on atrophy of the baboon iliac artery. J Vasc Surg (2008) 0.77
Platonin inhibited PDGF-BB-induced proliferation of rat vascular smooth muscle cells via JNK1/2-dependent signaling. Acta Pharmacol Sin (2011) 0.77
Differential regulation of human aortic smooth muscle cell proliferation by monocyte-derived macrophages from diabetic patients. PLoS One (2014) 0.77
Folic acid inhibits dedifferentiation of PDGF-BB-induced vascular smooth muscle cells by suppressing mTOR/P70S6K signaling. Am J Transl Res (2017) 0.76
Genetically modified human placenta‑derived mesenchymal stem cells with FGF‑2 and PDGF‑BB enhance neovascularization in a model of hindlimb ischemia. Mol Med Rep (2015) 0.76
Delivery as nanoparticles reduces imatinib mesylate-induced cardiotoxicity and improves anticancer activity. Int J Nanomedicine (2015) 0.76
Osteopontin, a missing link in PDGF-induced smooth muscle cell migration. Cardiovasc Res (2007) 0.76
Transcription factor cAMP response element modulator (Crem) restrains Pdgf-dependent proliferation of vascular smooth muscle cells in mice. Pflugers Arch (2014) 0.76
Immunolocalization of platelet-derived growth factor receptor-β (PDGFR-β) and pericytes in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Neuropathol Appl Neurobiol (2015) 0.76
The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway. Sci Rep (2016) 0.75
PDGF-D gene polymorphism is associated with increased cardiovascular mortality in elderly men. BMC Med Genet (2016) 0.75
The orphan nuclear receptor Nur77 inhibits low shear stress-induced carotid artery remodeling in mice. Int J Mol Med (2015) 0.75
Blockade of Urotensin II Receptor Prevents Vascular Dysfunction. Biomol Ther (Seoul) (2016) 0.75
Viscolin Inhibits In Vitro Smooth Muscle Cell Proliferation and Migration and Neointimal Hyperplasia In Vivo. PLoS One (2016) 0.75
miR-379 Inhibits Cell Proliferation, Invasion, and Migration of Vascular Smooth Muscle Cells by Targeting Insulin-Like Factor-1. Yonsei Med J (2017) 0.75
Drug- and Gene-eluting Stents for Preventing Coronary Restenosis. Chonnam Med J (2017) 0.75
Magnobovatol inhibits smooth muscle cell migration by suppressing PDGF-Rβ phosphorylation and inhibiting matrix metalloproteinase-2 expression. Int J Mol Med (2016) 0.75
Identify potential drugs for cardiovascular diseases caused by stress-induced genes in vascular smooth muscle cells. PeerJ (2016) 0.75
Scoparone interferes with STAT3-induced proliferation of vascular smooth muscle cells. Exp Mol Med (2015) 0.75
Tetrahydrobiopterin Inhibits PDGF-stimulated Migration and Proliferation in Rat Aortic Smooth Muscle Cells via the Nitric Oxide Synthase-independent Pathway. Korean J Physiol Pharmacol (2010) 0.75
Intrinsic Deregulation of Vascular Smooth Muscle and Myofibroblast Differentiation in Mesenchymal Stromal Cells from Patients with Systemic Sclerosis. PLoS One (2016) 0.75
Cytochrome P450 1B1 Contributes to the Development of Angiotensin II-Induced Aortic Aneurysm in Male Apoe(-/-) Mice. Am J Pathol (2016) 0.75
Bo-Gan-Whan regulates proliferation and migration of vascular smooth muscle cells. BMC Complement Altern Med (2016) 0.75
Transplantation of EPCs overexpressing PDGFR-β promotes vascular repair in the early phase after vascular injury. BMC Cardiovasc Disord (2016) 0.75
Inflammation and vascular smooth muscle cell dedifferentiation following carotid artery ligation. Physiol Genomics (2016) 0.75
A novel PDGF receptor inhibitor-eluting stent attenuates in-stent neointima formation in a rabbit carotid model. Mol Med Rep (2016) 0.75
Multi-omics analysis reveals regulators of the response to PDGF-BB treatment in pulmonary artery smooth muscle cells. BMC Genomics (2016) 0.75