Lars M Steinmetz

Author PubWeight™ 133.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A high-resolution map of transcription in the yeast genome. Proc Natl Acad Sci U S A 2006 11.81
2 Bidirectional promoters generate pervasive transcription in yeast. Nature 2009 9.29
3 Role of duplicate genes in genetic robustness against null mutations. Nature 2003 7.81
4 Evolutionary rate in the protein interaction network. Science 2002 7.75
5 Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 2012 6.22
6 High-resolution mapping of meiotic crossovers and non-crossovers in yeast. Nature 2008 6.10
7 Antisense artifacts in transcriptome microarray experiments are resolved by actinomycin D. Nucleic Acids Res 2007 5.54
8 Widespread bidirectional promoters are the major source of cryptic transcripts in yeast. Nature 2009 4.96
9 The genomic and transcriptomic landscape of a HeLa cell line. G3 (Bethesda) 2013 3.82
10 Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789. Proc Natl Acad Sci U S A 2007 3.52
11 Transcript mapping with high-density oligonucleotide tiling arrays. Bioinformatics 2006 2.94
12 Extensive variation in chromatin states across humans. Science 2013 2.83
13 Genetic analysis of variation in transcription factor binding in yeast. Nature 2010 2.69
14 Gene loops enhance transcriptional directionality. Science 2012 2.50
15 Integrative analysis of the mitochondrial proteome in yeast. PLoS Biol 2004 2.31
16 Extensive transcriptional heterogeneity revealed by isoform profiling. Nature 2013 2.14
17 Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality. Nat Struct Mol Biol 2013 2.11
18 Complex genetic interactions in a quantitative trait locus. PLoS Genet 2006 1.95
19 Gene regulation by antisense transcription. Nat Rev Genet 2013 1.90
20 Antisense expression increases gene expression variability and locus interdependency. Mol Syst Biol 2011 1.83
21 Elevated evolutionary rates in the laboratory strain of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 2005 1.83
22 Trans-acting antisense RNAs mediate transcriptional gene cosuppression in S. cerevisiae. Genes Dev 2009 1.77
23 Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast. Genetics 2008 1.68
24 Extensive degradation of RNA precursors by the exosome in wild-type cells. Mol Cell 2012 1.67
25 Dissecting the genetic basis of resistance to malaria parasites in Anopheles gambiae. Science 2009 1.63
26 Functional consequences of bidirectional promoters. Trends Genet 2011 1.61
27 Set3 HDAC mediates effects of overlapping noncoding transcription on gene induction kinetics. Cell 2012 1.61
28 easyRNASeq: a bioconductor package for processing RNA-Seq data. Bioinformatics 2012 1.55
29 High-resolution transcription atlas of the mitotic cell cycle in budding yeast. Genome Biol 2010 1.51
30 Execution of the meiotic noncoding RNA expression program and the onset of gametogenesis in yeast require the conserved exosome subunit Rrp6. Proc Natl Acad Sci U S A 2010 1.39
31 Assessing systems properties of yeast mitochondria through an interaction map of the organelle. PLoS Genet 2006 1.31
32 An efficient method for genome-wide polyadenylation site mapping and RNA quantification. Nucleic Acids Res 2013 1.30
33 RNA polymerase II collision interrupts convergent transcription. Mol Cell 2012 1.28
34 The baker's yeast diploid genome is remarkably stable in vegetative growth and meiosis. PLoS Genet 2010 1.20
35 Genome-wide allele- and strand-specific expression profiling. Mol Syst Biol 2009 1.20
36 System-wide identification of RNA-binding proteins by interactome capture. Nat Protoc 2013 1.15
37 Mosaic genome architecture of the Anopheles gambiae species complex. PLoS One 2007 1.12
38 Genotype-environment interactions reveal causal pathways that mediate genetic effects on phenotype. PLoS Genet 2013 1.09
39 Rrp6p controls mRNA poly(A) tail length and its decoration with poly(A) binding proteins. Mol Cell 2012 1.07
40 Alternative polyadenylation diversifies post-transcriptional regulation by selective RNA-protein interactions. Mol Syst Biol 2014 1.01
41 A yeast-based assay identifies drugs active against human mitochondrial disorders. Proc Natl Acad Sci U S A 2011 0.97
42 Role of histone modifications and early termination in pervasive transcription and antisense-mediated gene silencing in yeast. Nucleic Acids Res 2014 0.92
43 An evaluation of high-throughput approaches to QTL mapping in Saccharomyces cerevisiae. Genetics 2013 0.92
44 Natural single-nucleosome epi-polymorphisms in yeast. PLoS Genet 2010 0.91
45 Accumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae. RNA 2011 0.91
46 Genotyping 1000 yeast strains by next-generation sequencing. BMC Genomics 2013 0.90
47 Systematic screens for human disease genes, from yeast to human and back. Mol Biosyst 2007 0.89
48 Genome-wide survey of post-meiotic segregation during yeast recombination. Genome Biol 2011 0.89
49 Genome-wide polyadenylation site mapping. Methods Enzymol 2012 0.89
50 Re-analysis of data and its integration. FEBS Lett 2005 0.88
51 Capturing cellular machines by systematic screens of protein complexes. Trends Microbiol 2006 0.88
52 Drift and conservation of differential exon usage across tissues in primate species. Proc Natl Acad Sci U S A 2013 0.87
53 Multiple genomic changes associated with reorganization of gene regulation and adaptation in yeast. Mol Biol Evol 2013 0.83
54 Natural sequence variants of yeast environmental sensors confer cell-to-cell expression variability. Mol Syst Biol 2013 0.83
55 Genetic modifiers of chromatin acetylation antagonize the reprogramming of epi-polymorphisms. PLoS Genet 2012 0.83
56 Experimental relocation of the mitochondrial ATP9 gene to the nucleus reveals forces underlying mitochondrial genome evolution. PLoS Genet 2012 0.82
57 The role of Ctk1 kinase in termination of small non-coding RNAs. PLoS One 2013 0.82
58 Array-based genotyping in S.cerevisiae using semi-supervised clustering. Bioinformatics 2009 0.81
59 Identification of mitochondrial disease genes through integrative analysis of multiple datasets. Methods 2008 0.80
60 Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchange. Nucleic Acids Res 2011 0.79
61 Genome-wide transcriptome analysis in yeast using high-density tiling arrays. Methods Mol Biol 2011 0.77
62 Silencing of genes and alleles by RNAi in Anopheles gambiae. Methods Mol Biol 2013 0.77
63 Erratum: Modulation of mRNA and lncRNA expression dynamics by the Set2-Rpd3S pathway. Nat Commun 2017 0.75
64 High-density tiling microarray analysis of the full transcriptional activity of yeast. Methods Mol Biol 2014 0.75