Published in Infect Immun on July 01, 2004
The Legionella pneumophila replication vacuole: making a cosy niche inside host cells. Nat Rev Microbiol (2008) 4.09
Amoebae as training grounds for intracellular bacterial pathogens. Appl Environ Microbiol (2005) 2.59
Acquisition of the vacuolar ATPase proton pump and phagosome acidification are essential for escape of Francisella tularensis into the macrophage cytosol. Infect Immun (2008) 1.77
Legionella pneumophila glucosyltransferase inhibits host elongation factor 1A. Proc Natl Acad Sci U S A (2006) 1.48
Incomplete activation of macrophage apoptosis during intracellular replication of Legionella pneumophila. Infect Immun (2005) 1.44
Leading a sheltered life: intracellular pathogens and maintenance of vacuolar compartments. Cell Host Microbe (2009) 1.40
Exploitation of evolutionarily conserved amoeba and mammalian processes by Legionella. Trends Microbiol (2012) 1.16
Indispensable role for the eukaryotic-like ankyrin domains of the ankyrin B effector of Legionella pneumophila within macrophages and amoebae. Infect Immun (2010) 1.12
Identification of Legionella pneumophila-specific genes by genomic subtractive hybridization with Legionella micdadei and identification of lpnE, a gene required for efficient host cell entry. Infect Immun (2006) 1.05
Amoeba host-Legionella synchronization of amino acid auxotrophy and its role in bacterial adaptation and pathogenic evolution. Environ Microbiol (2013) 1.04
Maturation of the Legionella pneumophila-containing phagosome into a phagolysosome within gamma interferon-activated macrophages. Infect Immun (2005) 1.02
Host-dependent trigger of caspases and apoptosis by Legionella pneumophila. Infect Immun (2007) 1.01
Cellular microbiology and molecular ecology of Legionella-amoeba interaction. Virulence (2013) 0.99
The PmrA/PmrB two-component system of Legionella pneumophila is a global regulator required for intracellular replication within macrophages and protozoa. Infect Immun (2008) 0.97
Rapid escape of the dot/icm mutants of Legionella pneumophila into the cytosol of mammalian and protozoan cells. Infect Immun (2007) 0.97
Role for RpoS but not RelA of Legionella pneumophila in modulation of phagosome biogenesis and adaptation to the phagosomal microenvironment. Infect Immun (2006) 0.92
Molecular Characterization of Exploitation of the Polyubiquitination and Farnesylation Machineries of Dictyostelium Discoideum by the AnkB F-Box Effector of Legionella Pneumophila. Front Microbiol (2011) 0.91
Temporal and spatial trigger of post-exponential virulence-associated regulatory cascades by Legionella pneumophila after bacterial escape into the host cell cytosol. Environ Microbiol (2009) 0.90
Maintenance of vacuole integrity by bacterial pathogens. Curr Opin Microbiol (2013) 0.87
The global regulatory proteins LetA and RpoS control phospholipase A, lysophospholipase A, acyltransferase, and other hydrolytic activities of Legionella pneumophila JR32. J Bacteriol (2006) 0.86
Characterization of Legionella pneumophila pmiA, a gene essential for infectivity of protozoa and macrophages. Infect Immun (2005) 0.81
Rapid nutritional remodeling of the host cell upon attachment of Legionella pneumophila. Infect Immun (2013) 0.81
Seasonal diversity of planktonic protists in Southwestern Alberta rivers over a 1-year period as revealed by terminal restriction fragment length polymorphism and 18S rRNA gene library analyses. Appl Environ Microbiol (2012) 0.77
Selective requirement of the shikimate pathway of Legionella pneumophila for intravacuolar growth within human macrophages but not within Acanthamoeba. Infect Immun (2015) 0.75
Cytosolic Access of Intracellular Bacterial Pathogens: The Shigella Paradigm. Front Cell Infect Microbiol (2016) 0.75
The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. J Exp Med (1983) 8.82
Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae. J Clin Pathol (1980) 7.72
Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes. J Exp Med (1983) 7.65
Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol (1984) 4.88
Current views on the relationships between amoebae, legionellae and man. Isr J Med Sci (1986) 3.49
Expression of Legionella pneumophila virulence traits in response to growth conditions. Infect Immun (1998) 3.39
How the parasitic bacterium Legionella pneumophila modifies its phagosome and transforms it into rough ER: implications for conversion of plasma membrane to the ER membrane. J Cell Sci (2001) 2.83
Phenotypic modulation by Legionella pneumophila upon infection of macrophages. Infect Immun (1993) 2.79
Legionella pneumophila replication vacuoles mature into acidic, endocytic organelles. J Exp Med (2000) 2.40
Interaction of Legionella pneumophila with Acanthamoeba castellanii: uptake by coiling phagocytosis and inhibition of phagosome-lysosome fusion. Infect Immun (1996) 2.19
The phagosome containing Legionella pneumophila within the protozoan Hartmannella vermiformis is surrounded by the rough endoplasmic reticulum. Appl Environ Microbiol (1996) 2.04
The modulation of host cell apoptosis by intracellular bacterial pathogens. Trends Microbiol (2000) 1.93
Microinjection and growth of bacteria in the cytosol of mammalian host cells. Proc Natl Acad Sci U S A (2001) 1.71
Growth and killing of a Salmonella enterica serovar Typhimurium sifA mutant strain in the cytosol of different host cell lines. Microbiology (2002) 1.65
Disruption of the Salmonella-containing vacuole leads to increased replication of Salmonella enterica serovar typhimurium in the cytosol of epithelial cells. Infect Immun (2002) 1.56
Identification of macrophage-specific infectivity loci (mil) of Legionella pneumophila that are not required for infectivity of protozoa. Infect Immun (1998) 1.54
Macroautophagy is dispensable for intracellular replication of Legionella pneumophila in Dictyostelium discoideum. Mol Microbiol (2004) 1.54
Temporal pore formation-mediated egress from macrophages and alveolar epithelial cells by Legionella pneumophila. Infect Immun (2000) 1.51
Transcriptional regulation of the macrophage-induced gene (gspA) of Legionella pneumophila and phenotypic characterization of a null mutant. Mol Microbiol (1997) 1.50
Experimental transmission of legionnaires' disease by exposure to aerosols of Legionella pneumophila. Lancet (1982) 1.50
Cloning and molecular characterization of a Legionella pneumophila gene induced by intracellular infection and by various in vitro stress conditions. Mol Microbiol (1994) 1.49
Activation of caspase-3 by the Dot/Icm virulence system is essential for arrested biogenesis of the Legionella-containing phagosome. Cell Microbiol (2004) 1.48
Intracellular growth of Legionella pneumophila gives rise to a differentiated form dissimilar to stationary-phase forms. Infect Immun (2002) 1.40
Legionella pneumophila contains a type II general secretion pathway required for growth in amoebae as well as for secretion of the Msp protease. Infect Immun (1999) 1.39
Induced expression of the Legionella pneumophila gene encoding a 20-kilodalton protein during intracellular infection. Infect Immun (1998) 1.39
Type II protein secretion is a subset of the PilD-dependent processes that facilitate intracellular infection by Legionella pneumophila. Infect Immun (2001) 1.36
Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine. Infect Immun (2002) 1.35
Extracellular enzymes of Legionella pneumophila. Infect Immun (1981) 1.33
Salmonella and apoptosis: to live or let die? Microbes Infect (2001) 1.26
The mechanism of killing and exiting the protozoan host Acanthamoeba polyphaga by Legionella pneumophila. Environ Microbiol (2000) 1.20
Legionella pneumophila major acid phosphatase and its role in intracellular infection. Infect Immun (2001) 1.20
Different fates of Legionella pneumophila pmi and mil mutants within macrophages and alveolar epithelial cells. Microb Pathog (1998) 1.20
icmT is essential for pore formation-mediated egress of Legionella pneumophila from mammalian and protozoan cells. Infect Immun (2002) 1.19
Cytolytic and phospholipase C activity in Legionella species. J Gen Microbiol (1985) 1.19
Ultrastructure of pulmonary alveoli and macrophages in experimental Legionnaires' disease. J Pathol (1983) 1.17
Legionella pneumophila genes that encode lipase and phospholipase C activities. Microbiology (2002) 1.09
Legionella pneumophila induces apoptosis via the mitochondrial death pathway. Microbiology (2002) 1.04
Novel lysophospholipase A secreted by Legionella pneumophila. J Bacteriol (2001) 1.01
The C-terminus of IcmT is essential for pore formation and for intracellular trafficking of Legionella pneumophila within Acanthamoeba polyphaga. Mol Microbiol (2002) 0.97
Heterogeneity in intracellular replication and cytopathogenicity of Legionella pneumophila and Legionella micdadei in mammalian and protozoan cells. Microb Pathog (1999) 0.95
Novel phospholipase A activity secreted by Legionella species. J Bacteriol (2000) 0.92
Phospholipase A secreted by Legionella pneumophila destroys alveolar surfactant phospholipids. FEMS Microbiol Lett (2000) 0.90
How does Legionella pneumophila exit the host cell? Trends Microbiol (2002) 0.89
Macrophage apoptosis in microbial infections. Parasitology (1997) 0.86
In vitro secretion kinetics of proteins from Legionella pneumophila in comparison to proteins from non-pneumophila species. Microbiology (2001) 0.85
The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm. Cell Microbiol (2005) 3.51
Anti-apoptotic signalling by the Dot/Icm secretion system of L. pneumophila. Cell Microbiol (2006) 1.81
Molecular mimicry by an F-box effector of Legionella pneumophila hijacks a conserved polyubiquitination machinery within macrophages and protozoa. PLoS Pathog (2009) 1.68
Activation of caspase-3 by the Dot/Icm virulence system is essential for arrested biogenesis of the Legionella-containing phagosome. Cell Microbiol (2004) 1.48
Role for the Ankyrin eukaryotic-like genes of Legionella pneumophila in parasitism of protozoan hosts and human macrophages. Environ Microbiol (2008) 1.41
Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate. Neoplasia (2011) 1.34
icmT is essential for pore formation-mediated egress of Legionella pneumophila from mammalian and protozoan cells. Infect Immun (2002) 1.19
Hepatitis B virus sensitizes hepatocytes to TRAIL-induced apoptosis through Bax. J Immunol (2007) 1.17
Francisella-arthropod vector interaction and its role in patho-adaptation to infect mammals. Front Microbiol (2011) 1.07
Exploitation of host cell biology and evasion of immunity by francisella tularensis. Front Microbiol (2011) 1.05
Cell biology of the intracellular infection by Legionella pneumophila. Microbes Infect (2004) 1.04
Intracellular fate of Francisella tularensis within arthropod-derived cells. Environ Microbiol (2009) 1.01
Host-mediated post-translational prenylation of novel dot/icm-translocated effectors of legionella pneumophila. Front Microbiol (2010) 1.00
The C-terminus of IcmT is essential for pore formation and for intracellular trafficking of Legionella pneumophila within Acanthamoeba polyphaga. Mol Microbiol (2002) 0.97
Regulation of apoptosis and anti-apoptosis signalling by Francisella tularensis. Microbes Infect (2009) 0.94
Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/ENTPD1 null mice. Hepatology (2013) 0.94
High prevalence of subclinical thyroid dysfunction and the relationship between thyrotropin levels and cardiovascular risk factors in residents of the coastal area of China. Exp Clin Cardiol (2013) 0.93
Exploitation of Host Polyubiquitination Machinery through Molecular Mimicry by Eukaryotic-Like Bacterial F-Box Effectors. Front Microbiol (2010) 0.92
Acquisition of anoikis resistance reveals a synoikis-like survival style in BEL7402 hepatoma cells. Cancer Lett (2008) 0.91
Molecular characterization of the Dot/Icm-translocated AnkH and AnkJ eukaryotic-like effectors of Legionella pneumophila. Infect Immun (2009) 0.91
Molecular Characterization of Exploitation of the Polyubiquitination and Farnesylation Machineries of Dictyostelium Discoideum by the AnkB F-Box Effector of Legionella Pneumophila. Front Microbiol (2011) 0.91
Temporal and spatial trigger of post-exponential virulence-associated regulatory cascades by Legionella pneumophila after bacterial escape into the host cell cytosol. Environ Microbiol (2009) 0.90
Involvement of anoikis-resistance in the metastasis of hepatoma cells. Exp Cell Res (2008) 0.89
Deregulated NLRP3 and NLRP1 inflammasomes and their correlations with disease activity in systemic lupus erythematosus. J Rheumatol (2013) 0.89
The hepatitis B virus protein MHBs(t) sensitizes hepatoma cells to TRAIL-induced apoptosis through ERK2. Apoptosis (2007) 0.86
Aggregation formation mediated anoikis resistance of BEL7402 hepatoma cells. Folia Histochem Cytobiol (2008) 0.85
Intra-Vacuolar Proliferation of F. Novicida within H. Vermiformis. Front Microbiol (2011) 0.84
Up-regulation of Tropomyosin related kinase B contributes to resistance to detachment-induced apoptosis in hepatoma multicellular aggregations. Mol Biol Rep (2008) 0.84
Structure-function analysis of the C-terminus of IcmT of Legionella pneumophila in pore formation-mediated egress from macrophages. FEMS Microbiol Lett (2005) 0.81
Increased plasma levels of microparticles expressing CD39 and CD133 in acute liver injury. Transplantation (2013) 0.80
Upregulation of BNIP3 mediated by ERK/HIF-1α pathway induces autophagy and contributes to anoikis resistance of hepatocellular carcinoma cells. Future Oncol (2014) 0.79
Hepatitis B virus X protein modulates the apoptosis of hepatoma cell line induced by TRAIL. Sci China C Life Sci (2005) 0.78
One bacterial effector with two distinct catalytic activities by different strains. EMBO Rep (2013) 0.78
Blockade of preS2 down-regulates the apoptosis of HepG2.2.15 cells induced by TRAIL. Biochem Biophys Res Commun (2008) 0.78
Serum microRNA panel for early diagnosis of the onset of hepatocellular carcinoma. Medicine (Baltimore) (2017) 0.78
High dose of extracellular ATP switched autophagy to apoptosis in anchorage-dependent and anchorage-independent hepatoma cells. Purinergic Signal (2013) 0.77
A PCR based method to construct small interference RNA expression vectors. Mol Biol Rep (2008) 0.75
Characterizing ozone pollution in a petrochemical industrial area in Beijing, China: a case study using a chemical reaction model. Environ Monit Assess (2015) 0.75