PubRank

Dong-Er Zhang

Author PubWeight™ 120.66‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 UBP43 (USP18) specifically removes ISG15 from conjugated proteins. J Biol Chem 2002 3.52
2 Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proc Natl Acad Sci U S A 2008 3.13
3 UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity. EMBO J 2006 2.84
4 Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation. Mol Cell Biol 2004 2.70
5 Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection. Nat Med 2004 2.59
6 Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus. Nat Immunol 2011 2.51
7 A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis. Nat Med 2006 2.36
8 Protein ISGylation modulates the JAK-STAT signaling pathway. Genes Dev 2003 2.24
9 High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction. J Biol Chem 2003 2.24
10 The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase. J Biol Chem 2005 2.19
11 The 8;21 translocation in leukemogenesis. Oncogene 2004 2.18
12 Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochem Biophys Res Commun 2005 2.18
13 Interferon-stimulated gene 15 and the protein ISGylation system. J Interferon Cytokine Res 2010 2.14
14 RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells. Blood 2013 2.00
15 ISG15 inhibits Nedd4 ubiquitin E3 activity and enhances the innate antiviral response. J Biol Chem 2008 1.98
16 ISG15: the immunological kin of ubiquitin. Semin Cell Dev Biol 2004 1.87
17 Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling. Mol Cell Biol 2006 1.80
18 Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection. J Virol 2008 1.73
19 Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo. Blood 2006 1.66
20 Alpha interferon induces long-lasting refractoriness of JAK-STAT signaling in the mouse liver through induction of USP18/UBP43. Mol Cell Biol 2009 1.61
21 Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development. Proc Natl Acad Sci U S A 2004 1.60
22 ISG15: a ubiquitin-like enigma. Front Biosci 2005 1.58
23 ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP. Genes Dev 2007 1.57
24 Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron 2010 1.57
25 Dysregulation of protein modification by ISG15 results in brain cell injury. Genes Dev 2002 1.57
26 Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool. Blood 2011 1.54
27 SON controls cell-cycle progression by coordinated regulation of RNA splicing. Mol Cell 2011 1.52
28 Attenuation of AML1-ETO cellular dysregulation correlates with increased leukemogenic potential. Blood 2013 1.46
29 Negative effects of GM-CSF signaling in a murine model of t(8;21)-induced leukemia. Blood 2012 1.42
30 Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling. J Immunol 2005 1.42
31 RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis. Front Biosci (Landmark Ed) 2012 1.37
32 Different roles for two ubiquitin-like domains of ISG15 in protein modification. J Biol Chem 2008 1.31
33 ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway. EMBO Rep 2009 1.30
34 Acute myeloid leukemia with the 8q22;21q22 translocation: secondary mutational events and alternative t(8;21) transcripts. Blood 2007 1.29
35 ISG15, not just another ubiquitin-like protein. Biochem Biophys Res Commun 2003 1.29
36 Lipopolysaccharide activates the expression of ISG15-specific protease UBP43 via interferon regulatory factor 3. J Biol Chem 2002 1.25
37 AML1/RUNX1 phosphorylation by cyclin-dependent kinases regulates the degradation of AML1/RUNX1 by the anaphase-promoting complex. Mol Cell Biol 2006 1.18
38 MicroRNA programs in normal and aberrant stem and progenitor cells. Genome Res 2011 1.17
39 ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin. Biochem Biophys Res Commun 2005 1.17
40 The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO. Blood 2007 1.17
41 AML1/ETO oncoprotein is directed to AML1 binding regions and co-localizes with AML1 and HEB on its targets. PLoS Genet 2008 1.17
42 Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival. Blood 2008 1.16
43 Disruption of the NHR4 domain structure in AML1-ETO abrogates SON binding and promotes leukemogenesis. Proc Natl Acad Sci U S A 2008 1.14
44 The level of hepatitis B virus replication is not affected by protein ISG15 modification but is reduced by inhibition of UBP43 (USP18) expression. J Immunol 2008 1.10
45 The hematopoietic transcription factor AML1 (RUNX1) is negatively regulated by the cell cycle protein cyclin D3. Mol Cell Biol 2005 1.08
46 t(8;21)(q22;q22) Fusion proteins preferentially bind to duplicated AML1/RUNX1 DNA-binding sequences to differentially regulate gene expression. Blood 2008 1.07
47 PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential. Blood 2012 1.07
48 USP18 inhibits NF-κB and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex. J Exp Med 2013 1.02
49 Ubp43 regulates BCR-ABL leukemogenesis via the type 1 interferon receptor signaling. Blood 2007 1.02
50 Negative regulation of ISG15 E3 ligase EFP through its autoISGylation. Biochem Biophys Res Commun 2007 1.02
51 RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis. Blood 2008 1.02
52 Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages. Biochem Biophys Res Commun 2007 0.99
53 UBP43, an ISG15-specific deconjugating enzyme: expression, purification, and enzymatic assays. Methods Enzymol 2005 0.99
54 Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes. PLoS Pathog 2013 0.99
55 Evidence for annexin II-S100A10 complex and plasmin in mobilization of cytokine activity of human TrpRS. J Biol Chem 2007 0.99
56 Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10. EMBO Mol Med 2013 0.99
57 N-ethyl-N-nitrosourea-induced mutation in ubiquitin-specific peptidase 18 causes hyperactivation of IFN-αß signaling and suppresses STAT4-induced IFN-γ production, resulting in increased susceptibility to Salmonella typhimurium. J Immunol 2010 0.97
58 Expression of the runt homology domain of RUNX1 disrupts homeostasis of hematopoietic stem cells and induces progression to myelodysplastic syndrome. Blood 2012 0.97
59 Increased cerebral protein ISGylation after focal ischemia is neuroprotective. J Cereb Blood Flow Metab 2011 0.95
60 The ISG15 isopeptidase UBP43 is regulated by proteolysis via the SCFSkp2 ubiquitin ligase. J Biol Chem 2004 0.95
61 Expression of AML/Runx and ETO/MTG family members during hematopoietic differentiation of embryonic stem cells. Exp Hematol 2007 0.93
62 Combined gene expression and DNA occupancy profiling identifies potential therapeutic targets of t(8;21) AML. Blood 2012 0.92
63 Two independent mechanisms promote expression of an N-terminal truncated USP18 isoform with higher DeISGylation activity in the nucleus. J Biol Chem 2011 0.92
64 Erythrocyte membrane-cloaked polymeric nanoparticles for controlled drug loading and release. Nanomedicine (Lond) 2013 0.92
65 Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model. EMBO Mol Med 2013 0.92
66 A simple and quick method to concentrate MSCV retrovirus. Blood Cells Mol Dis 2004 0.92
67 Activation of double-stranded RNA-activated protein kinase (PKR) by interferon-stimulated gene 15 (ISG15) modification down-regulates protein translation. J Biol Chem 2012 0.91
68 RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element. EMBO J 2011 0.90
69 SON protein regulates GATA-2 through transcriptional control of the microRNA 23a~27a~24-2 cluster. J Biol Chem 2013 0.89
70 Lipid-insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles. Nanoscale 2013 0.89
71 The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner. Oncogene 2003 0.88
72 A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy. Blood 2006 0.87
73 Retinoic acid-induced protein ISGylation is dependent on interferon signal transduction. Blood Cells Mol Dis 2006 0.86
74 Ubp43 gene expression is required for normal Isg15 expression and fetal development. Reprod Biol Endocrinol 2007 0.84
75 Persistent altered fusion transcript splicing identifies RUNX1-RUNX1T1+ AML patients likely to relapse. Eur J Haematol 2009 0.83
76 Nitrosylation of ISG15 prevents the disulfide bond-mediated dimerization of ISG15 and contributes to effective ISGylation. J Biol Chem 2008 0.83
77 Usp18 promotes conventional CD11b+ dendritic cell development. J Immunol 2012 0.82
78 Phosphorylation of AML1/RUNX1 regulates its degradation and nuclear matrix association. Mol Cancer Res 2005 0.82
79 Cell type dependent regulation of multidrug resistance-1 gene expression by AML1-ETO. Blood Cells Mol Dis 2007 0.82
80 AML1-FOG2 fusion protein in myelodysplasia. Blood 2005 0.81
81 Hematopoietic cells from Ube1L-deficient mice exhibit an impaired proliferation defect under the stress of bone marrow transplantation. Blood Cells Mol Dis 2010 0.81
82 Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene. J Biol Chem 2004 0.81
83 ISG15 modulates development of the erythroid lineage. PLoS One 2011 0.80
84 Alteration of tumor spectrum by ISGylation in p53-deficient mice. Cancer Biol Ther 2009 0.80
85 The mitochondrial pathway and reactive oxygen species are critical contributors to interferon-α/β-mediated apoptosis in Ubp43-deficient hematopoietic cells. Biochem Biophys Res Commun 2012 0.79
86 Deficiency of a potential 3p21.3 tumor suppressor gene UBE1L (UBA7) does not accelerate lung cancer development in K-rasLA2 mice. Lung Cancer 2008 0.78
87 p53 alterations in myeloid leukemia. Acta Haematol 2004 0.78
88 Inability of RUNX1/AML1 to breach AML1-ETO block of embryonic stem cell definitive hematopoiesis. Blood Cells Mol Dis 2007 0.77
89 Cooperation between RUNX1-ETO9a and novel transcriptional partner KLF6 in upregulation of Alox5 in acute myeloid leukemia. PLoS Genet 2013 0.77
90 SERPINB13 is a novel RUNX1 target gene. Biochem Biophys Res Commun 2011 0.76
91 ISG15 regulates IFN-γ immunity in human mycobacterial disease. Cell Res 2012 0.76
92 Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells. Blood 2013 0.75
93 RUNX1-ETO induces a type I interferon response which negatively effects t(8;21)-induced increased self-renewal and leukemia development. Leuk Lymphoma 2013 0.75
94 Murine Herc6 Plays a Critical Role in Protein ISGylation In Vivo and Has an ISGylation-Independent Function in Seminal Vesicles. J Interferon Cytokine Res 2014 0.75