Published in J Mol Recognit on June 30, 2004
Altered dimer interface decreases stability in an amyloidogenic protein. J Biol Chem (2008) 1.50
Systemic amyloidoses. Annu Rev Biochem (2013) 1.34
Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2. Blood (2008) 1.21
Structural insights into the role of mutations in amyloidogenesis. J Biol Chem (2008) 1.12
The critical role of the constant region in thermal stability and aggregation of amyloidogenic immunoglobulin light chain. Biochemistry (2010) 1.05
Kinetic control in protein folding for light chain amyloidosis and the differential effects of somatic mutations. J Mol Biol (2013) 1.04
Current perspectives on cardiac amyloidosis. Am J Physiol Heart Circ Physiol (2011) 1.04
Structural alterations within native amyloidogenic immunoglobulin light chains. J Mol Biol (2009) 1.01
Localization of a conformational epitope common to non-native and fibrillar immunoglobulin light chains. Biochemistry (2007) 0.98
Light chain amyloidosis - current findings and future prospects. Curr Protein Pept Sci (2009) 0.96
Differential effects on light chain amyloid formation depend on mutations and type of glycosaminoglycans. J Biol Chem (2014) 0.89
Tyrosine residues mediate fibril formation in a dynamic light chain dimer interface. J Biol Chem (2012) 0.88
Amyloid formation in light chain amyloidosis. Curr Top Med Chem (2012) 0.86
Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes. PLoS One (2015) 0.85
Inhibition of pathologic immunoglobulin-free light chain production by small interfering RNA molecules. Exp Hematol (2010) 0.84
Mutations can cause light chains to be too stable or too unstable to form amyloid fibrils. Protein Sci (2015) 0.79
Cell Damage in Light Chain Amyloidosis: FIBRIL INTERNALIZATION, TOXICITY AND CELL-MEDIATED SEEDING. J Biol Chem (2016) 0.78
Site-directed mutagenesis reveals regions implicated in the stability and fiber formation of human λ3r light chains. J Biol Chem (2014) 0.76
Epigallocatechin-3-gallate preferentially induces aggregation of amyloidogenic immunoglobulin light chains. Sci Rep (2017) 0.75
The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains. J Mol Biol (2016) 0.75
Differential recruitment efficacy of patient-derived amyloidogenic and myeloma light chain proteins by synthetic fibrils-A metric for predicting amyloid propensity. PLoS One (2017) 0.75
Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): a consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis, Tours, France, 18-22 April 2004. Am J Hematol (2005) 5.64
Toxin-antitoxin modules as bacterial metabolic stress managers. Trends Biochem Sci (2005) 2.88
Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc Natl Acad Sci U S A (2006) 2.51
Transmissibility of systemic amyloidosis by a prion-like mechanism. Proc Natl Acad Sci U S A (2002) 2.01
Prevalence and morphology of leukocyte chemotactic factor 2-associated amyloid in renal biopsies. Kidney Int (2010) 1.83
Comparative mapping of Brassica juncea and Arabidopsis thaliana using Intron Polymorphism (IP) markers: homoeologous relationships, diversification and evolution of the A, B and C Brassica genomes. BMC Genomics (2008) 1.79
Radioimmunodetection of amyloid deposits in patients with AL amyloidosis. Blood (2010) 1.76
Neutron diffraction studies of Escherichia coli dihydrofolate reductase complexed with methotrexate. Proc Natl Acad Sci U S A (2006) 1.70
Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity. Cell (2010) 1.65
Doc of prophage P1 is inhibited by its antitoxin partner Phd through fold complementation. J Biol Chem (2008) 1.62
General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold. J Biol Chem (2008) 1.60
Pseudomonas aeruginosa lectin LecB is located in the outer membrane and is involved in biofilm formation. Microbiology (2005) 1.59
Immunodiagnostic capabilities of anti-free immunoglobulin light chain monoclonal antibodies. Am J Clin Pathol (2008) 1.54
Molecular basis of gyrase poisoning by the addiction toxin CcdB. J Mol Biol (2005) 1.43
Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies. J Mol Biol (2005) 1.41
Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB. Chem Biol (2008) 1.34
Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation. Proc Natl Acad Sci U S A (2006) 1.32
Do caregiver management strategies influence patient behaviour in dementia? Int J Geriatr Psychiatry (2004) 1.28
Molecular basis for passive immunotherapy of Alzheimer's disease. Proc Natl Acad Sci U S A (2007) 1.26
New toxins homologous to ParE belonging to three-component toxin-antitoxin systems in Escherichia coli O157:H7. Mol Microbiol (2010) 1.25
Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain. Mol Cell (2009) 1.22
Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology. J Pathol (2005) 1.21
The impact of clerkships on students' specialty preferences: what do undergraduates learn for their profession? Med Educ (2008) 1.21
Leukocyte chemotactic factor 2 (LECT2)-associated renal amyloidosis: a case series. Am J Kidney Dis (2010) 1.21
Micro-imaging of amyloid in mice. Methods Enzymol (2006) 1.19
Identification of phosphorylation sites on the yeast ribonucleotide reductase inhibitor Sml1. J Biol Chem (2003) 1.17
Behavioural disturbances in dementia patients and quality of the marital relationship. Int J Geriatr Psychiatry (2003) 1.15
Intricate interactions within the ccd plasmid addiction system. J Biol Chem (2001) 1.13
Quantitative high-resolution microradiographic imaging of amyloid deposits in a novel murine model of AA amyloidosis. Amyloid (2005) 1.13
How thioredoxin can reduce a buried disulphide bond. J Mol Biol (2004) 1.12
Gender-specific phenotypic expression and screening strategies in C282Y-linked haemochromatosis: a study of 9396 French people. Br J Haematol (2002) 1.10
Noninvasive prediction of cirrhosis in C282Y-linked hemochromatosis. Hepatology (2002) 1.10
Expression of odontogenic ameloblast-associated protein (ODAM) in dental and other epithelial neoplasms. Mol Med (2008) 1.09
Cancer predisposing missense and protein truncating BARD1 mutations in non-BRCA1 or BRCA2 breast cancer families. Hum Mutat (2010) 1.09
Characterization of systemic amyloid deposits by mass spectrometry. Methods Enzymol (2006) 1.09
Gender-related differences in general practice preferences: longitudinal evidence from the Netherlands 1982-2001. Health Policy (2005) 1.09
Quantitative tomography of early-onset spontaneous AA amyloidosis in interleukin 6 transgenic mice. Comp Med (2008) 1.08
Cognitive functioning in spousal caregivers of dementia patients: findings from the prospective MAASBED study. Age Ageing (2006) 1.07
The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin. J Mol Biol (2007) 1.06
Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly. Proc Natl Acad Sci U S A (2006) 1.04
Identification of the N-terminal peptide binding site of glucose-regulated protein 94. J Biol Chem (2004) 1.04
The oxidase DsbA folds a protein with a nonconsecutive disulfide. J Biol Chem (2007) 1.04
Elicitation of allergic asthma by immunoglobulin free light chains. Proc Natl Acad Sci U S A (2005) 1.03
Ferritin structure from Mycobacterium tuberculosis: comparative study with homologues identifies extended C-terminus involved in ferroxidase activity. PLoS One (2011) 1.03
Shortage in general practice despite the feminisation of the medical workforce: a seeming paradox? A cohort study. BMC Health Serv Res (2008) 1.02
Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH. J Mol Biol (2005) 1.02
Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires. J Biol Chem (2005) 1.01
Transthyretin-derived senile systemic amyloidosis: clinicopathologic and structural considerations. Amyloid (2003) 1.00
Photochemical surface mapping of C14S-Sml1p for constrained computational modeling of protein structure. Anal Biochem (2005) 1.00
Diagnostic and therapeutic potential of amyloid-reactive IgG antibodies contained in human sera. J Immunol (2006) 0.98
The fimbrial adhesin F17-G of enterotoxigenic Escherichia coli has an immunoglobulin-like lectin domain that binds N-acetylglucosamine. Mol Microbiol (2003) 0.98
Localization of a conformational epitope common to non-native and fibrillar immunoglobulin light chains. Biochemistry (2007) 0.98
Orchestration of secretory protein folding by ER chaperones. Biochim Biophys Acta (2013) 0.98
Radioimaging of light chain amyloid with a fibril-reactive monoclonal antibody. J Nucl Med (2006) 0.97
Acoustic deposition with NIMS as a high-throughput enzyme activity assay. Anal Bioanal Chem (2012) 0.96
A prospective study of the effects of behavioral symptoms on the institutionalization of patients with dementia. Int Psychogeriatr (2005) 0.96
A molecular basis for nonsecretory myeloma. Blood (2004) 0.96
Rational decision-making about treatment and care in dementia: a contradiction in terms? Patient Educ Couns (2011) 0.96
Human plasma contains cross-reactive Abeta conformer-specific IgG antibodies. Biochemistry (2008) 0.96
Two different types of amyloid deposits--apolipoprotein A-IV and transthyretin--in a patient with systemic amyloidosis. Lab Invest (2004) 0.95
Impact of hemochromatosis screening in patients with indeterminate results: the hemochromatosis and iron overload screening study. Genet Med (2006) 0.95
Chemical basis for the affinity maturation of a camel single domain antibody. J Biol Chem (2004) 0.94
Structural determinants for activity and specificity of the bacterial toxin LlpA. PLoS Pathog (2013) 0.94
Protein structures by spallation neutron crystallography. J Synchrotron Radiat (2008) 0.94
Renal apolipoprotein A-I amyloidosis associated with a novel mutant Leu64Pro. Am J Kidney Dis (2004) 0.94
Dissecting the role of critical residues and substrate preference of a Fatty Acyl-CoA Synthetase (FadD13) of Mycobacterium tuberculosis. PLoS One (2009) 0.93
Odontogenic ameloblast-associated protein nature of the amyloid found in calcifying epithelial odontogenic tumors and unerupted tooth follicles. Amyloid (2008) 0.93
RNA-seq based SNPs in some agronomically important oleiferous lines of Brassica rapa and their use for genome-wide linkage mapping and specific-region fine mapping. BMC Genomics (2013) 0.92
Influence of the germline sequence on the thermodynamic stability and fibrillogenicity of human lambda 6 light chains. Proteins (2008) 0.92
Isolectins I-A and I-B of Griffonia (Bandeiraea) simplicifolia. Crystal structure of metal-free GS I-B(4) and molecular basis for metal binding and monosaccharide specificity. J Biol Chem (2001) 0.92
Untangle, a tool for filtering overlapping diffraction patterns from multicrystals. Acta Crystallogr D Biol Crystallogr (2004) 0.92
Vibrio cholerae ParE2 poisons DNA gyrase via a mechanism distinct from other gyrase inhibitors. J Biol Chem (2010) 0.92
Is Helicobacter pylori being treated appropriately? A study of inpatients and outpatients in a tertiary care centre. Can J Gastroenterol (2007) 0.91
Auer Rod in a Neutrophil in a Nonmalignant Condition. Turk J Haematol (2016) 0.91
Recognition of the intrinsically flexible addiction antidote MazE by a dromedary single domain antibody fragment. Structure, thermodynamics of binding, stability, and influence on interactions with DNA. J Biol Chem (2003) 0.91
Phage display and peptide mapping of an immunoglobulin light chain fibril-related conformational epitope. Biochemistry (2007) 0.91
Energetics of structural transitions of the addiction antitoxin MazE: is a programmed bacterial cell death dependent on the intrinsically flexible nature of the antitoxins? J Biol Chem (2005) 0.90
"For most of us Africans, we don't just speak": a qualitative investigation into collaborative heterogeneous PBL group learning. Adv Health Sci Educ Theory Pract (2010) 0.90
Coupling of domain swapping to kinetic stability in a thioredoxin mutant. J Mol Biol (2008) 0.90
Isolated amyloidosis presenting with lumbosacral radiculoplexopathy: description of two cases and pathogenic review. J Peripher Nerv Syst (2006) 0.90
Unreliability of immunohistochemistry for typing amyloid deposits. Arch Pathol Lab Med (2008) 0.89
Histidine hydrogen-deuterium exchange mass spectrometry for probing the microenvironment of histidine residues in dihydrofolate reductase. PLoS One (2011) 0.89
Solving the phase problem for carbohydrate-binding proteins using selenium derivatives of their ligands: a case study involving the bacterial F17-G adhesin. Acta Crystallogr D Biol Crystallogr (2003) 0.88
Anti-amyloidogenic activity of IgGs contained in normal plasma. J Clin Immunol (2010) 0.88
Senile seminal vesicle amyloid is derived from semenogelin I. J Lab Clin Med (2005) 0.87
Natural mutations in two homoeologous TT8 genes control yellow seed coat trait in allotetraploid Brassica juncea (AABB). Theor Appl Genet (2013) 0.87
QTL mapping of yield-associated traits in Brassica juncea: meta-analysis and epistatic interactions using two different crosses between east European and Indian gene pool lines. Theor Appl Genet (2012) 0.87
The structural basis for peptidomimetic inhibition of eukaryotic ribonucleotide reductase: a conformationally flexible pharmacophore. J Med Chem (2008) 0.86
Yo Jyo Hen Shi Ko (YHK) improves transaminases in nonalcoholic steatohepatitis (NASH): a randomized pilot study. Dig Dis Sci (2006) 0.86
Plant lectin-like antibacterial proteins from phytopathogens Pseudomonas syringae and Xanthomonas citri. Environ Microbiol Rep (2012) 0.86
Crystallization of CcdB in complex with a GyrA fragment. Acta Crystallogr D Biol Crystallogr (2004) 0.86
The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct. Acta Crystallogr D Biol Crystallogr (2004) 0.85
Energetic basis of uncoupling folding from binding for an intrinsically disordered protein. J Am Chem Soc (2013) 0.85
Impact of natural variation in bacterial F17G adhesins on crystallization behaviour. Acta Crystallogr D Biol Crystallogr (2005) 0.84
Inherent anti-amyloidogenic activity of human immunoglobulin gamma heavy chains. J Biol Chem (2009) 0.84
Driving forces of gyrase recognition by the addiction toxin CcdB. J Biol Chem (2009) 0.84